Abstract:
Die Erfindung betrifft eine Probenanalysevorrichtung zum Bestimmen von Proben in einer Probenmatrix mit mehreren Probevolumen, insbesondere in einer Mikrotiterplatte, mit einer Aufnahmeeinrichtung mit einer Aufnahme für eine Probenmatrix, die mehrere Probevolumen aufweist, einer ersten Messeinrichtung, die konfiguriert ist, Proben in der Probenmatrix, wenn diese in der Aufnahme angeordnet ist, mittels einer Nass- oder Feuchtmessung zu bestimmen, einer zweiten Messeinrichtung, die konfiguriert ist, weitere Proben in der Probenmatrix, die von den Proben verschieden sind, oder in einer anderen Probenmatrix, wenn diese in der Aufnahme angeordnet ist, mittels einer Trockenmessung zu bestimmen, und einer Verlagerungseinrichtung, die an die Aufnahmeeinrichtung koppelt und konfiguriert ist, die Aufnahmeeinrichtung zwischen einer Ladestellung und mehreren Messstellungen zu verlagern, derart, dass die Aufnahme in verschiedene Messstellungen verlagerbar ist, die entweder der ersten oder der zweiten Messeinrichtung zugeordnet sind. Weiterhin ist ein Verfahren zum Bestimmen von Proben in einer oder mehreren Probenmatrizen geschaffen, die jeweils mit mehreren Probevolumen gebildet sind.
Abstract:
A fluorometry device suitable for determining the concentration of species in a biological sample (622), the device comprising: a light source (605) adapted to provide an excitation beam; a plurality of optical devices (610), each optical device comprising an emission filter (660), an excitation filter (641), and a beam splitter (645), each optical device configured to receive the source beam to produce an excitation beam configured to impinge on an array of samples so as to form an emission beam; means for moving (615, 640) each of the plurality of optical devices into the excitation beam; a detector (625) configured to receive the emission beam and generate a data signal that includes information representative of a concentration of DNA in each sample of the plurality of samples.
Abstract:
The invention relates to a method for determining an analyte in a water sample by means of a mobile water analysis arrangement (10), comprising a mobile base unit (14) and an exchangeable single-use test element (16), inserted in the base unit (14). The single-use test element (16) comprises: a sample line (20) with an inlet opening (22) for accommodating the water sample, a measuring section (28) forming the measuring run for determining an analyte in the water sample and a first reagent section (23) lying behind the measuring section (28) and a reagent (24), arranged in the sample line (20) in the reagent section (23). The base unit (14) comprises: a test element housing for housing the inserted test element (16) and a measuring device (30), the measuring run of which is formed by the test element measuring section (28). The method comprises the following method steps: inserting the test element (16) in the test element housing on the base unit (14), pumping the water sample on from the inlet opening (22) to the measuring section (28), firstly analysing the water sample in the measuring section (28) by means of the measuring device (30), then pumping on the water sample from the measuring section (28) into the first reagent section (23), then pumping the water sample back from the first reagent section (23) to the measuring section (28) with a second analysis of the water sample in the measuring section (28) by means of the measuring device (30). By means of said method it is possible to determine a so-called sample blind value with an automatic mobile water analysis arrangement before the analysis of the water sample or to carry out a standard addition.
Abstract:
A fluorometry device for determining concentration of spectrally distinguishable species in a biological sample, the device comprising: a light source adapted to provide a source beam;a plurality of sample wells; a plurality of optical devices comprising an excitation filter adapted to filter the source beam, an emission filter adapted to filter fluorescent emission light from the samples, and a beamsplitter to separate the source beam from the fluorescent emission light, wherein each of the plurality of optical devices is coupled to a movable platform, wherein the excitation filter, the emission filter, and the beamsplitter provide a first narrow wavelength range for excitation and a second narrow wavelength range for emission; a detector adapted to receive the fluorescent emission light emitted from the samples; and an optical element positioned to collimate the emission light and to reduce non-uniformities in the emission light prior to the emission light impinging the beamsplitter and/or positioned to collimate the excitation light and to reduce non-uniformities in the excitation light prior to the excitation light impinging the beamsplitter.
Abstract:
The invention relates to an optical instrument which is particularly suited for DNA PCR monitoring. The instrument comprises a plurality of spaced-apart reaction ingredient containers (1b), a light source (11) adapted to direct an excitation beam (22) toward the plurality of containers (1b), a Fresnel lens (3) disposed along an excitation beam path between the light source (11) and the plurality of containers (1b) and a detector (10) disposed along an excitation beam path and arranged to receive emission beams (26) emitted from the Fresnel lens (3) which is also disposed along an emission beam path between the plurality of containers (1b) and the detector (10).
Abstract:
A portable system and method for measuring the concentration of multiple chemical or biological substances where an onsite analysis of such substances is needed. The new and original handheld sensor system uses a disposable optical test element and a spectroscopic detector that measures the test element response to specific analytes through a change in light absorbance, luminescence, and other forms of light-based response. In this way, reflection light intensities indicative of the test element response can be used to measure the concentration of the target analytes. The sensor system is also capable of being interfaced to an information processing unit or computer so that analytical data can be manipulated or stored electronically.
Abstract:
Die Erfindung betrifft eine Haltestruktur (1), die zum Zusammenwirken mit einem optischen Sensormodul (2) und einem an der Haltestruktur befestigen Smartphone (3) eingerichtet ist, um ein optisches Analysesystem zu bilden. Die Erfindung betrifft außerdem ein optisches Sensormodul (2) für eine solche Haltestruktur sowie ein Set aus einer derartigen Haltestruktur und einem derartigen Sensormodul.