公开(公告)号：WO1994007407A1

公开(公告)日：1994-04-14

申请号：PCT/US1992008196

申请日：1992-09-25

Applicant: SAFETY TECHNOLOGY PARTNERS, LTD. ,  PHILLIPS, Mary, F. ,  HAWTHORNE, Jeffrey, S.

Inventor： SAFETY TECHNOLOGY PARTNERS, LTD.

IPC: A61B05/00

CPC classification number: G01N33/98

Abstract: A monitor device (102) which measures ethanol levels expelled through a subject's skin to monitor blood alcohol level with a gas content sensor (218) at regular or random intervals. The device differentiates between a positive reading caused by an external, interferant, gas and a positive reading caused by consumption of alcohol. The device has a temperature sensor (220) which monitors the skin temperature of the subject prior to performing the alcohol test to provide an indication of a barrier being placed between the device and the subject's skin or if the device has been removed from the subject. The device measures the distance from the subject's skin by means of a distance sensor (222) thereby preventing the subject from moving the device far enough away to provide an inaccurate indication of the amount of alcohol in the subject's blood and providing another tamper indication if the device is removed.

Abstract translation: 一种监测装置（102），其测量通过受试者的皮肤排出的乙醇水平，以用气体含量传感器（218）以规则或随机的间隔监测血液酒精含量。 该装置区分由外部，干扰物，气体和由酒精消耗引起的正面读数引起的正面读数。 该装置具有温度传感器（220），其在进行酒精测试之前监测受试者的皮肤温度，以提供放置在装置与被检者皮肤之间的障碍物的指示，或者该装置是否已经从被检体中移出。 该装置通过距离传感器（222）测量与受检者皮肤的距离，从而防止受试者移动设备足够远，以提供对象血液中酒精量的不精确指示，并提供另一个擅动指示，如果 设备被删除。

公开(公告)号：WO1994004072A1

公开(公告)日：1994-03-03

申请号：PCT/US1993007969

申请日：1993-08-23

Applicant: BRILL, Peter, L.

IPC: A61B05/00

CPC classification number: G06F19/3481 ,  A61B10/00 ,  G06F19/00 ,  G16H10/20 ,  G16H50/30

Abstract: A method and apparatus for measuring a patient's psychotherapy progress is provided. Initial patient mental health is measured by administering a questionnaire measuring three psychological variables. The three psychological variable measures are combined into a mental health index (69). Following a number of sessions of psychotherapy, the patient's subsequent psychological condition is again measured using the three psychological variables. Patient session records (42) are stored in a large database (20). Patient progress can thus be compared versus patient initial psychlological condition, typical patient outcomes as stored in the database (20), and patient improvement as a function of a number of sessions of psychotherapy can be determined. The system further provides a case manager with a measure of the effectiveness of continued psychotherapy sessions, and a basis of comparison of various psychotherapy providers.

Abstract translation: 提供了一种用于测量患者心理治疗进展的方法和装置。 初始患者的心理健康状况是通过管理一个测量三个心理变量的问卷进行测量的。 三项心理变量指标合并为精神卫生指标（69）。 经过多次心理治疗，患者随后的心理状况再次用三个心理变量来衡量。 患者会话记录（42）存储在大数据库（20）中。 因此，患者进展可以与患者初始心理状况，存储在数据库中的典型患者结果（20）进行比较，并且可以确定患者改善作为心理治疗的次数的函数。 该系统进一步向病例管理员提供持续心理治疗会话的有效性的量度，以及各种心理治疗提供者的比较基础。

公开(公告)号：WO1994003104A1

公开(公告)日：1994-02-17

申请号：PCT/US1993006967

申请日：1993-07-23

Applicant: SAPIDYNE, INC.

Inventor： SAPIDYNE, INC. ,  LACKIE, Steve, J.

IPC: A61B05/00

CPC classification number: G01N21/645 ,  G01N21/0303 ,  G01N21/6428 ,  G01N21/75 ,  G01N33/54313 ,  Y10S435/808 ,  Y10S436/805

Abstract: A system (30) for assaying a fluid sample. The system (30) comprising a lens (33) capable of focussing both excitation and fluorescent radiation, a fluid-flow conducting conduit (42) being provided in the lens (33) extending transversely of the optical axis of and through the focal region of the latter. At least one mechanical screen (38A, 38B) is disposed adjacent the focal region in the conduit (42) to arrest passage of beads (40) as a function of bead diameter. The beads (40) are precoated with at least a moiety of a ligand/conjugated complex and preferably transparent to both the excitation and fluorescent radiation.

Abstract translation: 一种用于测定流体样品的系统（30）。 所述系统（30）包括能够聚焦激发和荧光辐射的透镜（33），设置在所述透镜（33）中的流体导流导管（42）横向延伸穿过所述透镜 后者。 至少一个机械筛（38A，38B）设置在导管（42）中的焦点区域附近，以阻止珠（40）的通过作为珠直径的函数。 珠（40）预先涂覆有配体/共轭复合物的至少一部分，并且优选对激发和荧光辐射两者是透明的。

公开(公告)号：WO1993025141A1

公开(公告)日：1993-12-23

申请号：PCT/US1993005573

申请日：1993-06-07

Applicant: UNIVERSITY OF WASHINGTON

Inventor： UNIVERSITY OF WASHINGTON ,  HOCHMAN, Daryl ,  HAGLUND, Michael, M.

IPC: A61B05/00

CPC classification number: A61B5/0059 ,  A61B5/14553 ,  A61B5/4047 ,  A61B5/4064 ,  A61B5/4076 ,  A61B5/4094 ,  A61B90/36 ,  G06F19/00 ,  G06F19/321 ,  G16H15/00 ,  G16H40/63 ,  G16H50/20

Abstract: The present invention provides a method and apparatus for imaging margins, grade and dimensions of solid tumor tissue located in an area of interest, comprising illuminating the area of interest with high intensity, emr (electromagnetic radiation) containing the wave length of emr absorbed by a dye, obtaining a video signal of the area of interest as an averaged control image and processing the averaged control image into the averaged control frame, administering the dye by bolus injection into a vein circulating to the area of interest, obtaining a series of video images of the area of interest over time as subsequent images and processing each subsequent image as a subsequent frame, comparing each subsequent frame with the processed averaged control frame to obtain a series of difference images, and comparing each difference image for initial evidence of changed absorption within the area of interest which is the outline of solid tumor tissue, whereby tumor tissue is characterized by faster absorption of emr as a result of increased vascularity of solid tumor tissue and inability to clear the dye as fast as normal tissue.

Abstract translation: 本发明提供了一种用于对位于感兴趣区域中的实体肿瘤组织的边缘，等级和尺寸进行成像的方法和装置，包括以高强度照射所述感兴趣区域，所述emr（电磁辐射）包含由a 获得感兴趣区域的视频信号作为平均的控制图像，并将平均的控制图像处理到平均的控制帧中，通过快速喷射将染料施用到循环到感兴趣区域的静脉中，获得一系列视频图像 作为后续图像的感兴趣区域，并且将每个后续图像作为后续帧处理，将每个后续帧与经处理的平均控制帧进行比较以获得一系列差异图像，并将每个差异图像与变化吸收的初始证据进行比较 感兴趣的区域是实体肿瘤组织的轮廓，其中肿瘤组织的特征在于 由于固体肿瘤组织的血管分布增加，不能像正常组织一样快地清除染料，emr的吸收更快。

公开(公告)号：WO1993020747A1

公开(公告)日：1993-10-28

申请号：PCT/US1993003759

申请日：1993-04-21

Applicant: ST. JUDE MEDICAL, INC. ,  ROSAR, George, C. ,  BACHOFER, Ken, W. ,  POKORNEY, James, L. ,  GRAF, James, E.

Inventor： ST. JUDE MEDICAL, INC.

IPC: A61B05/00

CPC classification number: A61B18/1492 ,  A61B18/1206 ,  A61B18/1233 ,  A61B90/39 ,  A61B2017/00292 ,  A61B2018/00083 ,  A61B2018/00107 ,  A61B2018/00642 ,  A61B2018/00755 ,  A61B2018/00761 ,  A61B2018/00875 ,  A61B2018/1213 ,  A61B2018/124 ,  A61B2018/1286 ,  A61B2018/144

Abstract: A guide wire (15) for supporting monopolar arcing for cutting tissue and for ablating occlusions includes a flexible metal wire (302) including a distal end, an electrically insulating coating (306) extending along the wire, and an electrically and thermally insulating tip (310) having a distal end and attached to the wire, the wire extending through the electrically and thermally insulating tip and forming an electrode (312) at the distal ends of the wire and the tip. An electrosurgical apparatus for cutting tissue and for ablating occlusions includes a pulse generator (5, 6) having a variable output impedance for selectively generating a train of pulses of electrical energy for application to a guide wire (15) having an attached electrode. The pulse generator senses the load impedance and adjusts the output impedance to match the load impedance. The generator measures the relative electrical energy produced by an arc in response to a pulse, compares the relative electrical energy to a predetermined value to determine an energy difference, and adjusts the energy of a subsequent pulse to reduce the energy difference toward zero.

Abstract translation: 用于支撑用于切割组织并用于消融闭塞的单极电弧的导丝（15）包括柔性金属线（302），其包括远端，沿着线延伸的电绝缘涂层（306）和电绝热尖端 310），其具有远端并且附接到所述线，所述线延伸穿过所述电绝热顶端并在所述线的末端和所述尖端处形成电极（312）。 用于切割组织和用于消融闭塞的电外科设备包括具有可变输出阻抗的脉冲发生器（5,6），用于选择性地产生用于施加到具有附接电极的导线（15）的电能脉冲串。 脉冲发生器检测负载阻抗，并调整输出阻抗以匹配负载阻抗。 发电机响应于脉冲测量由电弧产生的相对电能，将相对电能与预定值进行比较以确定能量差，并且调整后续脉冲的能量以将能量差向零减小。

公开(公告)号：WO1993019663A1

公开(公告)日：1993-10-14

申请号：PCT/US1993002890

申请日：1993-03-25

Applicant: BOSTON SCIENTIFIC CORPORATION

Inventor： BOSTON SCIENTIFIC CORPORATION ,  ABELE, John, E.

IPC: A61B05/00

CPC classification number: A61B6/12 ,  A61M25/09 ,  A61M2025/09166 ,  A61M2025/09175 ,  A61M2205/32

Abstract: A calibrated guidewire for use in determining the magnitude of arterial occlusions in the body and a method of using the guidwire. The guidewire includes a flexible sleeve (9) having a distal end and a hemispherical tip (3) having a flat inner surface (4). A multifilar flexible coil (7) is disposed between the distal end of the sleeve and the tip. The coil has a uniform outer diameter and is formed by two sets of different wires (7a and 7b), one of which is radiotransparent and the other of which is radiopaque. The spacing between each of the sets is identical and is defined by the widths of each of the sets to provide regularly spaced radiotransparent areas of indicia that are observable as a fluoroscopic image to enable the user measure of the magnitude of an occlusion in a tubular structure in the body. The multifilar construction extends the entire length of the coil between the sleeve and the tip.

Abstract translation: 用于确定体内动脉闭塞的大小的校准导丝和使用该导丝的方法。 导丝包括具有远端的柔性套筒（9）和具有平坦内表面（4）的半球形尖端（3）。 多针柔性线圈（7）设置在套筒的远端和尖端之间。 线圈具有均匀的外径，并且由两组不同的线（7a和7b）形成，其中之一是无线电透射，另一组是不透射线的。 每个组之间的间隔是相同的，并且由每个组的宽度限定，以提供可视为荧光透视图像的标记的规则间隔的无线电透射区域，以使得用户可以测量管状结构中的闭塞量 在身上。 多针结构在套筒和尖端之间延伸线圈的整个长度。

公开(公告)号：WO1993018703A1

公开(公告)日：1993-09-30

申请号：PCT/US1993002323

申请日：1993-03-12

Applicant: MISSANELLI, John, S. ,  NAPONIC, Mearl, A.

IPC: A61B05/00

CPC classification number: A61B5/1464 ,  A61B5/14542

Abstract: An oximeter probe (5) is introduced through the vaginal canal (4) and applied to the scalp (9) or other readily accessible part of the fetus (1) while still in utero. The fetal oxygenation is monitored during the entire labor and delivery period to obtain instantaneous indications of any peripartum fetal distress. The probe comprises a clamping device which can be easily manipulated within the narrow confines of the partially dilated cervix (3).

Abstract translation: 将血氧计探针（5）通过阴道（4）引入并施用于头皮（9）或胎儿（1）的其他容易接近的部分，同时仍然在子宫内。 在整个劳动和交付期间监测胎儿氧合，以获得任何围产期胎儿窘迫的即时适应症。 该探头包括夹紧装置，其能够容易地在部分扩张的子宫颈（3）的狭窄范围内操作。

公开(公告)号：WO1993012710A1

公开(公告)日：1993-07-08

申请号：PCT/GB1992002392

申请日：1992-12-23

Applicant: MEDICINA LTD ,  WEBB, Andrew, Roy

Inventor： MEDICINA LTD

IPC: A61B05/00

CPC classification number: A61B5/14539 ,  A61B5/0071 ,  A61B5/0084 ,  A61B5/1459

Abstract: A gastric probe comprises a light source (23) connected by a first fibreoptic connector (22) to a light dispersing member (21), said member being disposed in a body of liquid contained in a gas permeable container (20), said liquid containing a compound adapted to fluoresce upon excitation by said light source, the intensity of the fluorescence being dependent on the concentration of gas within said liquid, a second fibreoptic connector (29) extending from a location within the container to a detector adapted to produce a signal indicative of the concentration of gas in said liquid.

Abstract translation: 胃探头包括通过第一光纤连接器（22）连接到光分散构件（21）的光源（23），所述构件设置在容纳在透气容器（20）中的液体体中，所述液体包含 适于在由所述光源激发时发荧光的化合物，所述荧光的强度取决于所述液体内的气体的浓度;第二光纤连接器（29），其从所述容器内的位置延伸到适于产生信号的检测器 表示所述液体中气体的浓度。

公开(公告)号：WO1992021281A1

公开(公告)日：1992-12-10

申请号：PCT/US1992004297

申请日：1992-05-21

Applicant: SUSI, Roger, E.

IPC: A61B05/00

CPC classification number: A61B5/6826 ,  A61B5/02427 ,  A61B5/0424 ,  A61B5/055 ,  A61B5/14552 ,  A61B5/6838 ,  G01R33/28

Abstract: An apparatus for remotely indicating characteristics of a patient, such as blood oxygen saturation or the like, while the patient is undergoing MRI, includes a probe (18) having first and second hinged portions (22, 24) for fitting on opposite sides of a body portion, such as a finger (20) or a toe. One embodiment provides for a remotely located light source, a photodetector (60) and a pair of fiberoptic cables (38, 82), one fiberoptic cable (38) carrying light from the source to the probe (18), and the other fiberoptic cable (82) carrying light after having passed through the patient (20) to a photodetector (60) at the remote location (12). The characteristics of the patient are determined by the light having passed through the body portion of a patient, the signals transmitted by the fiberoptic cables being insensitive to MRI magnetic fields.

Abstract translation: 一种用于在患者正在进行MRI的情况下远程指示患者的特征（例如血氧饱和度等）的装置包括具有第一和第二铰接部分（22,24）的探针，所述第一和第二铰接部分（22,24）用于安装在患者的相对侧上 身体部分，例如手指（20）或脚趾。 一个实施例提供了远程定位的光源，光电检测器（60）和一对光纤电缆（38,82），一个光纤电缆（38），其承载来自光源到探针（18）的光，以及另一光纤电缆 （82）在通过所述患者（20）之后携带光线到所述远程位置（12）处的光电检测器（60）。 患者的特征由穿过患者身体部分的光确定，由光纤电缆传输的信号对MRI磁场不敏感。

公开(公告)号：WO1992019151A1

公开(公告)日：1992-11-12

申请号：PCT/US1992003896

申请日：1992-05-06

Applicant: TARGET THERAPEUTICS, INC.

Inventor： TARGET THERAPEUTICS, INC. ,  SEPETKA, Ivan

IPC: A61B05/00

CPC classification number: A61M25/09 ,  A61M25/0054 ,  A61M2025/09091 ,  A61M2025/09166 ,  A61M2025/09175

Abstract: A catheter guide wire (10) comprising: a flexible, torqueable proximal wire section (13), a more flexible intermediate section (14) with a flexible polymer tube covering (19), and a most flexible distal end section (15). A helical ribbon coil (22) is wrapped about the intermediate core segment between the wire core and the polymer tube covering to increase radiopacity and improve torque transmission while retaining flexibility.

Abstract translation: 导管导丝（10），包括：柔性的，可扭转的近侧线段（13），具有柔性聚合物管覆盖物（19）的更灵活的中间部分（14）和最柔性的远端部分（15）。 螺旋带状线圈（22）围绕线芯和聚合物管覆盖物之间的中间纤芯段缠绕以增加不透射线性并且在保持柔性的同时提高扭矩传递。