公开(公告)号：WO1989005115A1

公开(公告)日：1989-06-15

申请号：PCT/US1988004339

申请日：1988-12-05

Applicant: GENERAL ELECTRIC COMPANY

Inventor： GENERAL ELECTRIC COMPANY ,  ROEMER, Peter, Bernard ,  EDELSTEIN, William, Alan ,  HAYES, Cecil, Edward

IPC: A61B05/05

CPC classification number: G01R33/3415

Abstract: A method for simultaneously receiving a different NMR response signal from each of a plurality of closely-spaced surface coils, first provides an array of a plurality of the surface coils, each positioned so as to have substantially no interaction with all adjacent surface coils. A different NMR response signal is received from an associated portion of the sample enclosed within an imaging volume defined by the array. Each different NMR response signal is used to construct a different one of a like plurality of NMR images of the sample, with the plurality of different images then being combined, on a point-by-point basis, to produce a single composite NMR image of a total sample portion from which NMR response signal contribution was received by any of the array of surface coils. Interactions between non-adjacent surface coils are minimized by coupling each onto an associated preamplifier. A nuclear magnetic resonance (NMR) signal acquisition apparatus includes a cylindrical array of overlapping coils. Coupling of currents between coils due to re-radiation of received signals, in particular noise currents, is reduced by presenting a high impedance to each coil, thereby reducing the current circulating in each coil. A PREDAMP circuit is disclosed which utilizes the input impedance of a preamplifier, transformed through a quarter-wavelength transmission line segment, to achieve the high input impedance for the coil. As a result, multiple images, each with a high signal-to-noise ratio (SNR), can be simultaneously obtained. A method is disclosed for combining the multiple images into a composite image with optimum SNR, taking into account the phase shifts between images resulting from the spatial orientation of the coils.

Abstract translation: 同时从多个紧密间隔的表面线圈中的每一个接收不同的NMR响应信号的方法首先提供多个表面线圈的阵列，每个表面线圈定位成与所有相邻的表面线圈基本上没有相互作用。 从包含在由阵列定义的成像体积内的样品的相关部分接收不同的NMR响应信号。 每个不同的NMR响应信号用于构建样品的相同多个NMR图像中的不同的一个，然后在逐点的基础上组合多个不同的图像，以产生单个的NMR图像 通过表面线圈阵列中的任何阵列接收到NMR响应信号贡献的总样本部分。 通过将每个相邻的前置放大器相耦合，使非相邻表面线圈之间的相互作用最小化。 核磁共振（NMR）信号采集装置包括重叠线圈的圆柱形阵列。 由于接收信号的再辐射特别是噪声电流，线圈之间的电流耦合通过对每个线圈呈现高阻抗而减小，从而减少在每个线圈中循环的电流。 公开了一种PREDAMP电路，其利用通过四分之一波长传输线段转换的前置放大器的输入阻抗来实现线圈的高输入阻抗。 结果，可以同时获得具有高信噪比（SNR）的多个图像。 公开了一种用于将多个图像组合成具有最佳SNR的合成图像的方法，其考虑了由线圈的空间取向产生的图像之间的相移。

公开(公告)号：WO1988007835A1

公开(公告)日：1988-10-20

申请号：PCT/US1988001069

申请日：1988-04-08

Applicant: BIOMAGNETIC TECHNOLOGIES, INC.

Inventor： BIOMAGNETIC TECHNOLOGIES, INC. ,  CRUM, Duane, B. ,  WESLEY, Ronald, C. ,  GREENBLATT, Richard, E. ,  TOUSSAINT, Robert, M. ,  HIRSCHKOFF, Eugène, C.

IPC: A61B05/05

CPC classification number: F17C3/085 ,  A61B5/04005 ,  F17C2203/0391 ,  F17C2203/0631 ,  F17C2203/0663 ,  F17C2209/228 ,  F17C2221/017 ,  F17C2223/0161 ,  F17C2270/0509 ,  F17C2270/0536 ,  G01R33/0358

Abstract: Apparatus (12) for performing sensitive magnetic measurements using cryogenically cooled instrumentation (72), wherein the instrumentation (72) is separated from the bubbles present in a cryogenic cooling fluid. In one embodiment, the magnetic measurement instrumentation (72) is placed in a tail piece (31) joined by heat conducting bolts (64) to a dewar (30) containing a cryogenic fluid, and heat from the instrumentation is conducted to the cryogenic fluid heat sink by metallic strips (70) reaching to the bolts (64). The cryogenic fluid does not contact the instrumentation (72) directly, resulting in a significantly reduced level of noise in the instrumentation (72). The tail piece (31) may also be evacuated to avoid pressure and temperature variations that may cause noise and affect the magnetic instrumentation (72).

公开(公告)号：WO1986002819A1

公开(公告)日：1986-05-22

申请号：PCT/GB1985000521

申请日：1985-11-15

Applicant: SUTTON, John, Andrew

IPC: A61B05/05

CPC classification number: A61B5/0535

Abstract: Apparatus for monitoring body functions comprises oscillator means (1) for generating a very high frequency oscillation, an oscillator driven constant current generating source (2), at least one pair of current driven electrodes (4) for attachment to the body of a patient, at least two pairs of voltage sensing electrodes (5) for attachment to the body of the patient, tuner/voltage amplifier means (6) tuned to the frequency of the generator means (1), converter means (7) for measuring impedance changes between pairs of voltage sensing electrodes (5), impedance indicator means (8), isolating circuit means (9) for receiving signals from the impedance converter (7), filter means (10) for excluding electronic or biological fluctuations from the equipment or the subject and a impedance offset control, and recorder means (11 or 12) for recording process and analysing the subject signals, the subject signals being received by the recorder means (11 or 12) as separate signals. Methods of producing a record of the function and volume of a hollow visceral organ are also described.

公开(公告)号：WO1983003746A1

公开(公告)日：1983-11-10

申请号：PCT/SE1983000148

申请日：1983-04-20

Applicant: KAROLINSKA INSTITUTET ,  TEDNER, Bo

Inventor： KAROLINSKA INSTITUTET

IPC: A61B05/05

CPC classification number: A61B5/4869 ,  A61B5/0535 ,  A61B5/0537 ,  A61B5/103 ,  A61B5/6824 ,  A61B5/6829

Abstract: Two high-frequency partial alternating currents of constant and equal size, 100 mu A, but with highly different frequencies, 1,5 and, respectively, 150 kHz, are delivered by means of a constant current source (K) to tape electrodes (E1 and, respectively, E2) about two places of peripherally remote relationship on the patient, for example one wrist and the diametrically opposed ankle. The voltage drop between two additional electrodes (E3 and, respectively, E4) located each near one the firstmentioned electrodes is measured by a detector (D) and divided into its two voltage components of different frequency, which components are proportional to the impedance of the body for the respective frequencies. The analogous component values are fed via an A/D-converter to a microprocessor (MD), which comprises a memory (M) for the measuring values received. To the microprocessor also information on the patient's weight and length are fed by setting devices (V, L). A first measurement is carried out and the result thereof is stored in the memory of the microprocessor. A second measurement is carried out, and a calculation of the change in the fluid balance relative to the first measurement now is carried out by the microprocessor according to an empirically constructed formula where DELTA V = change in fluid weight, k = a proportionality constant, S = body surface, based on patient's weight and length, Z1 and Z2 = impedance at 1,5 kHz and, respectively, 150 kHz at the second measuring occasion, Z1i 2i

Abstract translation: 恒定和相等尺寸的两个高频部分交流电流（100μA），但是具有高度不同的频率（1,5和150KHz）通过恒定电流源（K）传送到带状电极（E1 和E2）分别围绕患者的两个外围远程关系的位置，例如一个手腕和直径相对的脚踝。 通过检测器（D）测量位于第一个电极附近的两个附加电极（E3和分别为E4）之间的电压降，并分成其两个不同频率的电压分量，该分量与 身体各自的频率。 类似的组件值通过A / D转换器馈送到微处理器（MD），微处理器（MD）包括用于所接收的测量值的存储器（M）。 对于微处理器，还通过设置设备（V，L）馈送关于患者体重和长度的信息。 执行第一测量并将其结果存储在微处理器的存储器中。 进行第二次测量，并且现在通过微处理器根据经验构造的公式执行流体平衡相对于第一测量的变化的计算，其中DELTA V =流体重量的变化，k = a 比例常数，S =身体表面，基于患者的体重和长度，Z1和Z2 = 1,5kHz处的阻抗，在第二测量时刻分别为150kHz，Z1i和Z> 2i <=第一次相应的阻抗 测量时间（初始值），并显示在连接到微处理器的数字指示器（R）上。

公开(公告)号：WO1980000913A1

公开(公告)日：1980-05-15

申请号：PCT/US1979000975

申请日：1979-11-13

Applicant: ALLOCCA J

IPC: A61B05/05

CPC classification number: A61B5/0265 ,  A61B5/022 ,  A61B5/031 ,  A61B5/05

Abstract: Method and apparatus for noninvasive monitoring of the intracranial pressure of mammals. The method preferably consists of occluding the jugular vein (20) at a selected location so as to interrupt the flow of blood temporarily and then determining the rate of change of blood flow within the jugular vein upstream of such location over a predetermined period of time following its occlusion. Means (27) controlled by the operation of a computer (73) may be utilized for automatically occluding the jugular and for inducing detectable electrical signals representative of the flow of blood within the jugular.

Abstract translation: 用于非侵入性监测哺乳动物颅内压的方法和装置。 该方法优选地包括在选定位置闭塞颈静脉（20），以暂时中断血液流动，然后在预定的时间段内确定在该位置上游的颈静脉内血流变化的速率 其闭塞。 通过计算机（73）的操作控制的装置（27）可用于自动闭塞颈静脉，并用于诱导代表颈内血液流动的可检测的电信号。