公开(公告)号：WO2009131269A1

公开(公告)日：2009-10-29

申请号：PCT/KR2008/002793

申请日：2008-05-19

Applicant: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY ,  LEE, Yong Bok ,  KIM, Chang Ho ,  PARK, Dong Jin

Inventor： LEE, Yong Bok ,  KIM, Chang Ho ,  PARK, Dong Jin

IPC: F02B39/14

CPC classification number: F01D25/22 ,  F02B39/14 ,  F02C6/12 ,  F05D2220/40 ,  F05D2240/52 ,  F16C17/024 ,  F16C17/042

Abstract: The present invention relates to an oil-free turbocharger assembly using an airfoil bearing that may be useful in high speed conditions. The assembly can be cooled easily. A heat-proof coating can also be easily applied to the turbo charger's rotating shaft. In one embodiment, an oil-free turbocharger assembly has a constant distance between a journal portion and a rotating shaft so that the mass of the rotating body can be minimized and the rotating body assembly can have a small moment of inertia. The turbocharger in some embodiments of the invention may be cooled by a refrigerant which improves cooling efficiency. Each part of the rotating body assembly in some embodiments may be individually treated with a heat-proof process so that productivity can be improved.

Abstract translation: 本发明涉及一种使用可在高速条件下使用的翼型轴承的无油涡轮增压器组件。 组件可以轻松冷却。 耐热涂层也可以很容易地应用于涡轮增压器的旋转轴。 在一个实施例中，无油涡轮增压器组件在轴颈部分和旋转轴之间具有恒定的距离，使得旋转体的质量可以最小化并且旋转体组件可以具有小的惯性矩。 本发明的一些实施例中的涡轮增压器可以通过提高冷却效率的制冷剂来冷却。 在一些实施例中，旋转体组件的每个部分可以用耐热处理单独处理，从而可以提高生产率。

公开(公告)号：WO2009104840A2

公开(公告)日：2009-08-27

申请号：PCT/KR2008/003692

申请日：2008-06-26

Applicant: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY ,  CHOI, Won Kook ,  IE, Sang Yub ,  PARK, Dong Hee ,  KIM, Ji Hwan ,  LEE, Dong Soo ,  PARK, In Seok ,  SON, Dong Ik

Inventor： CHOI, Won Kook ,  IE, Sang Yub ,  PARK, Dong Hee ,  KIM, Ji Hwan ,  LEE, Dong Soo ,  PARK, In Seok ,  SON, Dong Ik

IPC: H01L33/00 ,  H01L41/04 ,  H01L41/09 ,  H01L41/113 ,  H01L51/00

CPC classification number: H05K3/027 ,  B06B1/0688 ,  B82Y30/00 ,  G06F3/016 ,  G06F3/0414 ,  H01L27/20 ,  H01L27/3225 ,  H01L41/0478 ,  H01L41/29 ,  H01L51/0042 ,  H01L51/426 ,  H01L51/52 ,  H01L2251/5338 ,  H04R1/04 ,  H04R17/005 ,  H04R31/00 ,  H04R2499/15 ,  H05K1/028 ,  H05K2201/015 ,  H05K2201/0326 ,  H05K2201/0329

Abstract: The present invention relates to an integrated, composite hybrid electric device in which various devices are formed as a single unit on one flexible substrate, and a fabrication method thereof. More particularly, the present invention a hybrid electric device in which a display device, a vibration-generating (or vibration-sensing) device, and a non-volatile memory device are formed on a single flexible piezoelectric polymer substrate into a single unit by using a flexible piezoelectric polymer substrate whose both surfaces are thinly deposited with a patterned transparent oxidation electrode, and a fabrication method thereof.

Abstract translation: 本发明涉及一种集成的复合混合电气装置及其制造方法，其中各种装置在一个柔性基板上形成为单个单元。 更具体地说，本发明是一种混合电动装置，其中通过使用在单个柔性压电聚合物基板上将显示装置，振动产生（或振动感测）装置和非易失性存储装置形成为单个装置 一种柔性压电聚合物基材及其制造方法，它们的两个表面均薄片地沉积有图案化的透明氧化电极。

公开(公告)号：WO2009102088A1

公开(公告)日：2009-08-20

申请号：PCT/KR2008/001492

申请日：2008-03-17

Applicant: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY ,  CHOI, Jun Ho ,  KANG, Sung Chul ,  LEE, Woo Sub ,  KIM, Mun Sang

Inventor： CHOI, Jun Ho ,  KANG, Sung Chul ,  LEE, Woo Sub ,  KIM, Mun Sang

IPC: B25J17/00

CPC classification number: B25J17/00 ,  Y10T74/20329 ,  Y10T74/20341

Abstract: The present invention relates to a device for generating stiffness and a method for controlling stiffness, which can generate stiffness by using elastic members and can control the stiffness, and a joint of a robot manipulator to which the device and method can be applied. The device for generating stiffness includes a rotating shaft; a plurality of elastic members fixed to the rotating shaft; upper and lower circular plates that are disposed so as to be spaced from each other with the elastic members interposed therebetween, are independently driven with respect to the rotating shaft by power generating units thereof, respectively, and respectively have slits of which the number is equal to the number of the elastic members; and a plurality of moving members that are inserted into the slits formed in the upper and lower circular plates, re¬ spectively, and are connected to the elastic members so as to move.

Abstract translation: 本发明涉及一种用于产生刚度的装置和一种用于控制刚度的方法，其可以通过使用弹性构件产生刚度并且可以控制刚度，以及可以应用该装置和方法的机器人操纵器的关节。 用于产生刚度的装置包括旋转轴; 固定在所述旋转轴上的多个弹性部件; 分别通过其间的弹性构件彼此间隔设置的上下圆板分别通过其发电单元相对于旋转轴被驱动，并且分别具有数量相等的狭缝 到弹性构件的数量; 以及多个移动构件，其被插入形成在上下圆形板中的狭缝中，并且连接到弹性构件以便移动。

公开(公告)号：WO2009096616A1

公开(公告)日：2009-08-06

申请号：PCT/KR2008/000603

申请日：2008-01-31

Applicant: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY ,  LEE, Changjoon Justin ,  KANG, Sang-Soo ,  HAN, Kyung-Suk ,  ROH, Eun-Joo ,  PARK, Jae-Yong

Inventor： LEE, Changjoon Justin ,  KANG, Sang-Soo ,  HAN, Kyung-Suk ,  ROH, Eun-Joo ,  PARK, Jae-Yong

IPC: A61K31/522

CPC classification number: A61K31/522

Abstract: An agent for inhibiting the activity of inositol-1,4,5-triphospate receptor subtype 3 (IP 3 R3), containing caffeine and/or its analogs, and/or their pharmaceutically acceptable salts, as an active ingredient, is provided. A composition for preventing and/or treating a disease associated with Ca 2+ release through IP 3 R3, containing the IP 3 R3 inhibiting agent, is also provided.

Abstract translation: 提供了用于抑制含有咖啡因和/或其类似物的肌醇-1,4,5-三磷酸受体亚型3（IP3R3）和/或其药学上可接受的盐作为活性成分的活性的药剂。 还提供了用于预防和/或治疗与包含IP3R3抑制剂的IP3R3释放相关的疾病的组合物。

公开(公告)号：WO2009072832A3

公开(公告)日：2009-06-11

申请号：PCT/KR2008/007197

申请日：2008-12-05

Applicant: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY ,  PARK, Sang Whan ,  LEE, Dong Yun ,  HAN, Jae Ho ,  YOON, Sung Ho ,  CHO, Gyung Sun

Inventor： PARK, Sang Whan ,  LEE, Dong Yun ,  HAN, Jae Ho ,  YOON, Sung Ho ,  CHO, Gyung Sun

IPC: C04B35/56

Abstract: The present invention relates to an economical manufacturing method of a machinable Cr 2 AlC sintered material, and particularly to a process of preparing a Cr 2 AlC sintered material, the process comprising (a) preparing chromium carbide powder comprising 95 vol % or more of Cr 7 C 3 and Cr 3 C 2 crystalline phase by conducting reduction of low-priced Cr 2 O 3 powder with a carbon source powder and (b) hot-pressing a powder mixture of the chromium carbide and Al powder. In the present invention, low-priced Cr 2 O 3 is used as a raw material, thus remarkably lowering the manufacture cost as compared to the conventional process. Moreover, Cr 2 AlC sintered material prepared according to the present invention is similar to or even better than the Cr 2 AlC fabricated by a conventional process in thermal, mechanical and electrical properties and machinability, and is thus capable of widening the applications of Cr 2 AlC sintered material as a structural material in industry.

公开(公告)号：WO2009066876A2

公开(公告)日：2009-05-28

申请号：PCT/KR2008/006275

申请日：2008-10-23

Applicant: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY ,  YANG, Hyun Ok ,  KWON, Hak Cheol ,  PARK, Hyun-Bong ,  YOO, Ji-Hye

Inventor： YANG, Hyun Ok ,  KWON, Hak Cheol ,  PARK, Hyun-Bong ,  YOO, Ji-Hye

IPC: C12N1/20

CPC classification number: C12R1/66 ,  A23L29/065 ,  A23L33/10 ,  A23L33/135 ,  C12N1/14 ,  C12N1/20 ,  C12P17/182 ,  C12P17/185 ,  C12P39/00 ,  C12R1/01

Abstract: The present invention relates to a co-culture method of Sphingomonas sp. bacterial strain and Aspergillus sp. fungus strain, in which the novel Sphingomonas sp. bacterial strain KMK-001 is cultured in a liquid medium and the novel Aspergillus sp. strain KMC-901 separately cultured in another liquid medium is added to the above culture solution, a novel glionitrin biosynthesized therefrom and a pharmaceutical composition comprising the said glionitrin or its pharmaceutically acceptable salt as an active ingredient. The glionitrin herein has strong cytotoxic effect on cancer cells and has antibiotic effect on 10 pathogenic bacteria including the novel Sphingomonas sp. bacterial strain KMK-001, so that it can be effectively applied in antibiotics or anti-cancer agents.

Abstract translation: 本发明涉及鞘氨醇单胞菌（Sphingomonas sp。）的共培养方法。 细菌菌株和曲霉菌属。 真菌菌株，其中新型鞘氨醇单胞菌属 将细菌菌株KMK-001在液体培养基中培养，并将新型曲霉属菌株 在另一种液体培养基中分别培养的菌株KMC-901加入到上述培养液中，由其生物合成新的glionitrin以及包含所述glionitrin或其药学上可接受的盐作为活性成分的药物组合物。 本发明的glionitrin对癌细胞具有强烈的细胞毒性作用，并且对包括新型鞘氨醇单胞菌属在内的10种致病菌具有抗生素作用。 细菌菌株KMK-001，因此可以有效应用于抗生素或抗癌药物。

公开(公告)号：WO2009054606A1

公开(公告)日：2009-04-30

申请号：PCT/KR2008/004842

申请日：2008-08-20

Applicant: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY ,  KIM, Su-Nam ,  UM, Byung Hun ,  KIM, Chul Young ,  LEE, Woo Jung ,  PARK, Yeon-Suk ,  KANG, Suk Woo

Inventor： KIM, Su-Nam ,  UM, Byung Hun ,  KIM, Chul Young ,  LEE, Woo Jung ,  PARK, Yeon-Suk ,  KANG, Suk Woo

IPC: A61K36/73

CPC classification number: A61K36/73

Abstract: The present invention relates to a composition containing Pentaphylloides fruticosa extract as an active ingredient. Pentaphylloides fruticosa extract of the present invention extracted by using water, alcohol or a mixture thereof as a solvent inhibits the activity of AP-1 (activator protein-1), a MMP-I transcription factor, inhibits type I collagenase, a skin matrix decomposing enzyme, but increases collagen, a major component of skin, so that it can be effectively used as a preparation for skin external application including cosmetics owing to its wrinkle and elasticity improving effects. In addition, Pentaphylloides fruticosa extract of the present invention has radical scavenging effect, so that it can also be effectively used as an antioxidative agent.

Abstract translation: 本发明涉及含有五倍体叶提取物作为活性成分的组合物。 通过使用水，醇或其混合物作为溶剂提取的本发明五倍体提取物抑制AP-1（活化蛋白-1），MMP-1转录因子的活性，抑制I型胶原酶，分解皮肤基质 酶，但是增加皮肤的主要成分的胶原蛋白，因此由于其皱纹和弹性改善效果，其可以有效地用作皮肤外用的制剂，包括化妆品。 此外，本发明的五倍子提取物具有自由基清除作用，因此也可有效地用作抗氧化剂。

公开(公告)号：WO2008146989A1

公开(公告)日：2008-12-04

申请号：PCT/KR2007/004945

申请日：2007-10-10

Applicant: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY ,  NHO, Chu Won ,  KANG, Kyung Su ,  LEE, Saet Byoul ,  DULAMJAV, Batsuren ,  JIGJIDSUREN, Tunsag

Inventor： NHO, Chu Won ,  KANG, Kyung Su ,  LEE, Saet Byoul ,  DULAMJAV, Batsuren ,  JIGJIDSUREN, Tunsag

IPC: A61K31/343

CPC classification number: A61K36/75 ,  A61K31/343

Abstract: The present invention relates to a pharmaceutical composition for the prevention and treatment of cancer comprising daurinol as an active ingredient, more precisely a pharmaceutical composition for the prevention and treatment of cancer comprising daurinol isolated from the medicinal plant of Mongolia, Haplophyllum dauricum or Haplophyllum cappadocicum, as an active ingredient. Daurinol can selectively block the S phase of cancer cell cycle to disturb the cycle and induce apoptosis stepwise, resulting in anticancer effect. Therefore, daurinol of the present invention can be used as a positive control chemical in the research and development field of cancer biology especially for cancer therapy and prevention. Daurinol also can be a promising candidate for a novel cell cycle blocker and a novel apoptosis inducer which could be effectively used for the prevention and treatment of cancer in the end.

Abstract translation: 本发明涉及一种用于预防和治疗癌症的药物组合物，其包含戴尼醇作为活性成分，更确切地说，涉及一种用于预防和治疗癌症的药物组合物，其包含从蒙古药用植物，Haplophyllum dauricum或Haplophyllum cappadocicum分离的多萝醇， 作为活性成分。 Daurinol可以选择性阻断癌细胞周期的S期，从而扰乱周期并逐步诱导凋亡，从而产生抗癌作用。 因此，本发明的daurinol可以用作癌症生物学研究和开发领域的阳性对照化学品，特别是用于癌症治疗和预防。 Daurinol也可能是新型细胞周期阻滞剂和新型细胞凋亡诱导因子的有希望的候选者，可以有效地用于预防和治疗癌症。

公开(公告)号：WO2008093919A1

公开(公告)日：2008-08-07

申请号：PCT/KR2007/003197

申请日：2007-07-02

Applicant: DONGBU HITEK CO., LTD. ,  KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY ,  PAE, Ae Nim ,  CHO, Yong Seo ,  CHOO, Hyunah ,  KIM, Hye-jung ,  KOH, Hun Yeong ,  PARK, Woo-Kyu ,  KONG, Jae Yang ,  CHAE, Myeong Yun ,  CHO, Insun ,  HWANG, Bong Woon ,  LEE, Dong Ha

Inventor： PAE, Ae Nim ,  CHO, Yong Seo ,  CHOO, Hyunah ,  KIM, Hye-jung ,  KOH, Hun Yeong ,  PARK, Woo-Kyu ,  KONG, Jae Yang ,  CHAE, Myeong Yun ,  CHO, Insun ,  HWANG, Bong Woon ,  LEE, Dong Ha

IPC: A61K31/18 ,  A61P25/28

CPC classification number: A61K31/18

Abstract: The present invention relates to N-benzyl-N-(2-dimethylamino-ethyl)-benzenesulfonamide compounds useful for the treatment of central nervous system (CNS) disorders.

Abstract translation: 本发明涉及可用于治疗中枢神经系统（CNS）病症的N-苄基-N-（2-二甲基氨基 - 乙基） - 苯磺酰胺化合物。

公开(公告)号：WO2008050933A1

公开(公告)日：2008-05-02

申请号：PCT/KR2006/005356

申请日：2006-12-08

Applicant: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY ,  LEE, Jaeyoung ,  NAM, Suk-Woo ,  LIM, Tae Hoon ,  OH, In Hwan ,  YOON, Sung Pil ,  HONG, Seong Ahn ,  HAN, Jonghee ,  KIM, Hyoung-Juhn ,  CHO, Eun Ae ,  HAHM, Hyung Chul ,  KIM, Yeong Cheon

Inventor： LEE, Jaeyoung ,  NAM, Suk-Woo ,  LIM, Tae Hoon ,  OH, In Hwan ,  YOON, Sung Pil ,  HONG, Seong Ahn ,  HAN, Jonghee ,  KIM, Hyoung-Juhn ,  CHO, Eun Ae ,  HAHM, Hyung Chul ,  KIM, Yeong Cheon

IPC: H01M12/08

CPC classification number: H01M16/006 ,  H01M8/04559 ,  H01M8/0494 ,  H01M8/04947 ,  H01M8/04955 ,  Y02E60/50

Abstract: Disclosed are an apparatus for portable fuel cell and an operation method thereof, wherein stabilization state after initial operation can be determined using OCV.

Abstract translation: 公开了便携式燃料电池的装置及其操作方法，其中可以使用OCV来确定初始操作之后的稳定状态。