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    DOCUMENT/IMAGE SEARCHING METHOD AND PROGRAM, AND DOCUMENT/IMAGE RECORDING AND SEARCHING DEVICE
    172.
    发明公开
    DOCUMENT/IMAGE SEARCHING METHOD AND PROGRAM, AND DOCUMENT/IMAGE RECORDING AND SEARCHING DEVICE 审中-公开
    DOKUMENT / / BILDSUCHVERFAHREN UND-PROGRMM，UND DOKUMENT / BILDAUFZEICHNUNGS- UND -SUCHEINRICHTUNG

    公开(公告)号：EP1914680A1

    公开(公告)日：2008-04-23

    申请号：EP06713810.7

    申请日：2006-02-15

    Applicant: Osaka Prefecture University Public Corporation

    Inventor： KISE, Koichi c/o Osaka Prefecture University Public Corporation ,  NAKAI, Tomohiro c/o Osaka Prefecture University Public Corporation ,  IWAMURA, Masakazu c/o Osaka Prefecture University Public Corporation

    IPC: G06T1/00 ,  G06F17/30

    CPC classification number: G06F17/30247 ,  G06K9/00442 ,  G06K9/4671 ,  G06K2209/01

    Abstract: A document/ image retrieval method for retrieving a document/image corresponding to a captured digital image from a database by comparing features calculated based on feature points of the captured digital image with features preliminarily calculated based on feature points of each of document/images stored in the database, the method comprising: extracting the feature points from the captured digital image; defining a local set of feature points for each of the extracted feature points; selecting feature points from the defined local set to define a feature point subset of the local set; determining invariant values as values characterizing the defined subset for combinations of the feature points in the subset, the invariant values being invariant to a geometric transformation; calculating a feature by combining the determined invariant values; and performing a voting process on the document/images in the database based on the preliminarily calculated features of the document/images; whereby the document/image corresponding to the captured digital image is retrieved from the database.

    Abstract translation: 一种文件/图像检索方法，用于通过将基于所捕获的数字图像的特征点计算的特征与基于存储在每个文档/图像的特征点预先计算的特征相比较来从数据库中检索与捕获的数字图像相对应的文档/图像 所述数据库，所述方法包括：从所捕获的数字图像中提取所述特征点; 为每个提取的特征点定义一组局部特征点; 从定义的本地集合中选择特征点以定义本地集合的特征点子集; 将不变值确定为表征所述子集中特征点的组合的所定义子集的值，所述不变值对于几何变换是不变的; 通过组合所确定的不变值来计算特征; 并且基于所述文档/图像的预先计算的特征，对所述数据库中的所述文档/图像执行投票处理; 从而从数据库中检索对应于所捕获的数字图像的文档/图像。

    NEUTRON DETECTOR AND NEUTRON IMAGE SENSOR
    173.
    发明公开
    NEUTRON DETECTOR AND NEUTRON IMAGE SENSOR 审中-公开
    NEUTRONENDETEKTOR UND NEUTRONENBILDSENSOR

    公开(公告)号：EP1862822A1

    公开(公告)日：2007-12-05

    申请号：EP06728616.1

    申请日：2006-03-03

    Applicant: Japan Science and Technology Agency ,  OSAKA PREFECTURAL GOVERNMENT ,  Osaka Prefecture University Public Corporation

    Inventor： SATOH, Kazuo ,  YOTSUYA, Tsutomu ,  ISHIDA, Takekazu ,  MIKI, Shigehito

    IPC: G01T3/04 ,  G01T1/26 ,  H01L39/00

    CPC classification number: G01T3/00 ,  G01T1/1606 ,  G01T3/08

    Abstract: An object of the present invention is to provide a neutron detector and a neutron imaging sensor which allow setting of sensitivity and time resolution through simple modification in the apparatus construction. A neutron detector includes a plurality of neutron detecting element sections, each the neutron detecting element section having; a superconducting element including a substrate having at least one of surfaces thereof formed of a dielectric material, a strip line of the superconducting material formed on the surface and electrodes formed at opposed ends of the strip line, resistance determining sections for determining generation of heat resulting from a nuclear reaction between a superconducting element in the strip line and neutrons, through detection of change in a resistance value of said strip line, heat dissipation setting sections provided on a back side portion of the substrate opposite to the surface having the strip line formed thereon, the heat dissipation setting sections setting dissipation characteristics of the heat resulting from the nuclear reaction, and the heat dissipation characteristics being differentiated from each other between/among the neutron detecting element sections.

    Abstract translation: 本发明的目的是提供一种中子检测器和中子成像传感器，其允许通过设备结构中的简单修改来设置灵敏度和时间分辨率。 中子检测器包括多个中子检测元件部分，每个中子检测元件部分具有： 超导元件，其包括具有由介电材料形成的表面中的至少一个的基板，形成在表面上的超导材料的带状线和形成在带状线的相对端的电极，用于确定产生的热量的电阻确定部 从带状线路中的超导元件与中子之间的核反应，通过检测所述带状线的电阻值的变化，设置在与形成有带状线的表面相对的基板的背侧部分上的散热设定部 散热设定部设定由核反应产生的热量的耗散特性，并且散热特性在中子检测元件部之间/之间彼此不同。

    NON-PEPTIDIC GAPDH AGGREGATION INHIBITOR
    177.
    发明公开
    NON-PEPTIDIC GAPDH AGGREGATION INHIBITOR 审中-公开
    非肽GAPDH聚合抑制剂

    公开(公告)号：EP3305762A1

    公开(公告)日：2018-04-11

    申请号：EP16807502.6

    申请日：2016-06-08

    Applicant: Osaka Prefecture University Public Corporation

    Inventor： NAKAJIMA Hidemitsu

    IPC: C07C323/57 ,  A61K31/164 ,  A61P9/10 ,  A61P25/00 ,  A61P25/14 ,  A61P25/16 ,  A61P25/28 ,  A61P43/00

    CPC classification number: A61K31/16 ,  A61K31/10 ,  A61K31/164 ,  A61P25/16 ,  A61P25/28 ,  C07C323/57

    Abstract: [Problem] Provided is a non-peptide compound which can be used as a GAPDH aggregation inhibitor. [Solution] Provided is a GAPDH aggregation inhibitor including as an active ingredient a compound represented by the chemical formula 1 wherein R 1 , R 2 , and R 3 are each independently a hydrogen atom, a halogen atom, or an aliphatic hydrocarbon group having a carbon number of from 1 to 10, a polysulfurized derivative thereof, or a pharmaceutically acceptable salt thereof. The present compound has a GAPDH aggregation inhibitory activity to suppress intracerebral aggregation of various proteins involved in cerebral neurodegenerative diseases, thereby contributing to improvement in various brain neurological diseases associated with aggregation of these proteins such as Alzheimer's disease, Parkinson's disease, and cerebral infarction, and prevention of advanced seriousness of these diseases.

    Abstract translation: [问题]提供了可用作GAPDH聚集抑制剂的非肽化合物。 本发明提供一种GAPDH聚集抑制剂，其包含以下化学式1表示的化合物作为活性成分，其中R 1，R 2和R 3各自独立地为氢原子，卤素原子或碳数为 1至10，其多硫化衍生物或其药学上可接受的盐。 本化合物具有GAPDH聚集抑制活性，可抑制脑神经变性疾病中所涉及的各种蛋白质的脑内聚集，有助于改善与阿兹海默症，帕金森病，脑梗塞等这些蛋白质的聚集相关的各种脑神经疾病， 预防这些疾病的严重性。

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