Abstract:
A microassay card (10) includes an upper layer (12) containing wells (14) for receiving a liquid sample (16). A second layer (20) of the card (10), beneath the first layer (12), includes a supporting surface (223) bound to a reactive species (114). A third layer (26) includes a superabsorbent support (26) impregnated with an indicator (228). Typically, the indicator (228) is a substrate (228) for an enzyme (16), such as a reduced dye precursor and a source of hydrogen peroxide necessary for the action of the enzyme (116), upon the substrate to cause a spectral change in the absorbent layer (26). By selecting the structure of the first (12) and second (20) layers, the card (10) can be formatted for a displacement assay or a competitive assay. The microassay card (10) of the present invention is particularly useful for drug testing.
Abstract:
Liquid light tube (guide) end cap assembly (155, 156) particularly useful in a system (10) for the clinical analyses of liquid biological samples for directing wavelengths of light. The assembly (155, 156) comprises a light guide (155) having projecting at one end portion thereof a quartz member (157) and a housing (156) for containing the end portion of the light guide (155) and the quartz member (157), thereby forming an aperture (159) between the quartz member (157) and the housing (156), the aperture (159) having a depth of between about 0.002 and 0.007 inches.
Abstract in simplified Chinese:本发明之萤光测定设备使用激励光源,大致同时的测定试料室内之多个试料,或同一试料之多个点。在激励光之照射位置具备有旋转试料台2,在上述之旋转试料台2,于圆周上形成有多个之穿通孔2a,试料设置部3可以插入到该穿通孔2a。使试料台2对激励光之照射位置进行相对移动,即使不更换试料室1内之试料,亦可以进行多个试料之萤光测定。
Abstract:
Die Erfindung betrifft Träger (20) mit mehreren Kapillaren (1), die in einer Ebene angeordnet sind und mechanisch am Träger (20) befestigt sind, wobei der Abstand benachbarter Kapillaren etwa 2,25mm oder ein ganzzahliges Vielfaches davon beträgt. Zumindest ein erstes freies Ende (11) jeder Kapillare (1) steht über den Träger (20) derart hervor, dass die freien Enden der Kapillaren (1) gleichzeitig in Kavitäten einer Mikrotiterplatte eingeführt werden können.
Abstract:
Polymeric fibers may be tested for optical properties; such as transparency in a manner that provides reproducible test results. A holder be used that is configured to hold polymeric fibers in a stacked, single file manner in which the polymeric fibers are held closely together. The fibers may be tested using an optical apparatus employing an integrating sphere.
Abstract:
Devices, systems, methods (as depicted in figure 1a), and compositions of matter can track and/or identify a library of elements, particularly for use with fluids, particulates, cells, and the like. Signals from one or more semiconductor nanocrystals may be combined to define spectral codes. Separation of signal wavelengths within dedicated wavelength ranges or windows facilitates differentiation of spectral codes, while calibration signals within the spectral codes can avoid ambiguity. Modeling based on prior testing can help derive libraries of acceptable codes.
Abstract:
Improved devices, systems (14), and methods for sensing and/or identifying signals from within a signal detection region are well-suited for identification of spectral codes. Large numbers of independently identifiable spectral codes can be generated by quite small bodies (12a, 12b), and a plurality of such bodies or probes (12a, 12b) may be present within a detection region. Simultaneously imaging of identifiable spectra (60) from throughout the detection region allows the probes (12a, 12b) to be identified. As the identifiable spectra can be treated as being generated from a point source within a much larger detection field, a prism, diffractive grading, holographic transmissive grading, or the like (56) can spectrally disperse the images of the labels across a sensor surface. A CCD (18) can identify the relative wavelengths of signals making up the spectra. Absolute signal wavelengths may be determined by determining positions of the labels, by an internal wavelength reference within the spectra (60), or the like.
Abstract:
Spectrophotometric apparatus and methodology suitable for continuous and long-term use. The apparatus includes a monochromator (13) providing pre-dispersed monochromatic light to the optical inputs of a pair of fiber optic cables (34-37) and a translator (43) for alternatively positioning the fiber optic cables (34-37) at the same location with respect to the monochromator output. One of the cables (61) conducts light to a sample under study while the other cable (35b) provides a reference for light intensity measurements. The methodology includes the steps of performing two scans through the monochromator output for each measurement on the sample. The fiber optic cables are moved between scans so that the cable employed in the latter scan occupies the former position of the cable employed in prior scan.