公开(公告)号：WO1992019150A1

公开(公告)日：1992-11-12

申请号：PCT/US1992003620

申请日：1992-04-29

Applicant: INNERSPACE, INC.

Inventor： INNERSPACE, INC. ,  FRUGARD, Gary, G. ,  BECKMAN, Ronald, B. ,  BOBO, Donald, E.

IPC: A61B05/00

CPC classification number: A61B5/14542 ,  A61B5/1473 ,  A61B5/6848

Abstract: A probe (10) adapted for direct insertion into the tissue of a patient, includes a needle (21) having walls defining an interior lumen (38) and a closed tip with a generally conical configuration. At least one sensor (14) capable of measuring a particular physiological parameter is disposed in the lumen. At least one window (41) is formed in the needle wall (36) along a path between the tissue and the sensor. A filler material (52) disposed along the path inhibits the passage of air or blood while facilitating transmission of the particular physiological parameter of interest such as oxygen, carbon dioxide, pH, and pressure.

Abstract translation: 适于直接插入患者组织的探针（10）包括具有限定内腔（38）的壁和具有大致圆锥形构造的封闭尖端的针（21）。 能够测量特定生理参数的至少一个传感器（14）设置在内腔中。 至少一个窗口（41）沿着组织和传感器之间的路径在针壁（36）中形成。 沿着路径设置的填充材料（52）抑制空气或血液的通过，同时促进感兴趣的特定生理参数如氧气，二氧化碳，pH和压力的传递。

公开(公告)号：WO1992016142A1

公开(公告)日：1992-10-01

申请号：PCT/US1992001894

申请日：1992-03-05

Applicant: VITAL SIGNALS, INC.

Inventor： VITAL SIGNALS, INC. ,  DIAB, Mohamed, K. ,  KIANI-AZARBAYJANY, Esmaiel

IPC: A61B05/00

CPC classification number: A61B5/6826 ,  A61B5/02427 ,  A61B5/6829 ,  A61B5/6838 ,  A61B2562/08 ,  H05K1/189

Abstract: An optical probe (100) which is particularly suited to reduce noise in measruements taken on an easily compressible material, such as a finger, a toe, a forehead, an earlobe, or a lip. The probe includes a base (110) having an aperture (120) which leads to a chamber (122). The base is placed adjacent a portion of the material, the chamber being placed directly adjacent any easily compressible portion of the material. A photodetector (126) is located within the chamber and does not contact the material. A light emitting diode (LED) (130) is affixed to the material, opposite the photodetector and above the chamber. The material which is supported by the aperture and therefore rests above or has intruded into the chamber is inhibited from compression since nothing comes in contact with this portion of the material, even when the material moves. Thus, light from the LED is directed through a stabilized portion of the material, such that the optical path length through which light travels is stabilized.

Abstract translation: 一种光学探针（100），其特别适用于减少在容易压缩的材料（例如手指，脚趾，前额，耳垂或唇部）上的测量中的噪音。 探针包括具有通向腔室（122）的孔（120）的底座（110）。 基部放置在材料的一部分附近，该腔被直接放置在材料的任何容易压缩的部分附近。 光电检测器（126）位于室内并且不接触材料。 发光二极管（LED）（130）被固定到材料上，与光电检测器相对并且在室上方。 被孔支撑并且因此搁置在腔室中或已经入侵到腔室中的材料被抑制，因为即使当材料移动时也不会与材料的这一部分接触。 因此，来自LED的光被引导通过材料的稳定部分，使得光行进的光路长度稳定。

公开(公告)号：WO1992014397A1

公开(公告)日：1992-09-03

申请号：PCT/DE1991000975

申请日：1991-12-14

Applicant: HAUCK, Peter

IPC: A61B05/00

CPC classification number: H04N21/478 ,  A61B5/0002 ,  A61B5/022 ,  H04N5/44513

Abstract: The invention calls for a TV set (1) to be equipped and modified for the display of data indicating the functioning of the human body, at least one measurement device (2) for the measurement of such data, in particular a measurement device for monitoring the functioning of the cardiovascular system, being associated with the TV set (1) and the data from the measurement device being transmitted to the TV set (1) and optionally displayed on the screen (3) of the TV set (1).

公开(公告)号：WO1992011802A1

公开(公告)日：1992-07-23

申请号：PCT/US1991009605

申请日：1991-12-18

Applicant: SMITHS INDUSTRIES MEDICAL SYSTEMS, INC.

Inventor： SMITHS INDUSTRIES MEDICAL SYSTEMS, INC. ,  HOLLISTER, William, H.

IPC: A61B05/00

CPC classification number: A61M5/3216 ,  A61B5/15003 ,  A61B5/150389 ,  A61B5/150496 ,  A61B5/150572 ,  A61B5/150671 ,  A61B5/150732 ,  A61B5/154 ,  A61M2005/3109

Abstract: To be used with a double-ended needle assembly and to prevent the accidental pricking of a user, or others, in a first embodiment of the present invention, a contain holder (2) mated with the needle assembly has a protective housing (18) integrally and flexibly connected thereto. To prevent a contaminated needle (22) from posing a risk to the user and others, the housing (18), connected to the container holder (2), is pivoted into alignment with the contaminated needle (22) such that the needle is retained by at least one locking mechanism (44, 46) integral of the housing (18). The container holder (2), along with the contaminated needle assembly, can then be disposed of. If the container holder (2) were to be reused, a second embodiment of the present invention provides for the connection of a protective housing (18) to the hub (62) of a double-ended needle assembly (64). For this embodiment, after use, the contaminated needle assembly (64) after having been properly retained in the protective housing (18) is removed from the reusable container housing (2) and disposed of.

公开(公告)号：WO1992011801A1

公开(公告)日：1992-07-23

申请号：PCT/SE1991000535

申请日：1991-08-13

Applicant: ÖBERG, Åke ,  LINDBERG, Lars-Göran ,  AXELSSON, Robert ,  SVENSON, Jan

IPC: A61B05/00

CPC classification number: A61B5/6876 ,  A61B5/0084 ,  A61B5/14532 ,  A61B5/1459 ,  A61B5/6884

Abstract: The invention relates to method and sensor for detecting specific parameters of a blood flow in a blood vessel in a living organism by detecting optical properties of the flowing blood, depending on said specific parameter, by using at least one optical plastic or glass fibre. The detection is effected according to the invention in a peripheral layer of blood plasma closest to the wall of the blood vessel the optical fiber being disposed adjacent said wall at the outside or inside surface thereof. The sensor comprises means (10) for applying one or more optical plastic or glass fibres (14, 15) to the outside surface of the wall of the blood vessel (11).

Abstract translation: 本发明涉及通过使用至少一种光学塑料或玻璃纤维，根据所述具体参数检测流动的血液的光学特性来检测活体中的血管中血流的特定参数的方法和传感器。 根据本发明，在最靠近血管壁的血浆的外周层中进行检测，该光纤在其外表面或内表面邻近所述壁设置。 传感器包括用于将一个或多个光学塑料或玻璃纤维（14,15）施加到血管（11）的壁的外表面的装置（10）。

公开(公告)号：WO1992010971A1

公开(公告)日：1992-07-09

申请号：PCT/US1991009732

申请日：1991-12-20

Applicant: BALLARD MEDICAL PRODUCTS

Inventor： BALLARD MEDICAL PRODUCTS ,  STRICKLAND, Richard, D.

IPC: A61B05/00

CPC classification number: A61M16/0463 ,  A61M1/0058 ,  A61M1/0084 ,  A61M16/0404 ,  A61M16/0459 ,  A61M16/0486 ,  A61M25/0068 ,  A61M25/01 ,  A61M2016/0027 ,  A61M2025/1052 ,  A61M2205/32 ,  A61M2210/0618 ,  A61M2210/0625 ,  A61M2210/1039 ,  A61M2230/005

Abstract: An outer catheter so sized and configured so as to extend from a point below the first bifurcation of the trachea through the upper respiratory system of the patient is disposed about an inner catheter having a tip secured in the opening at the distal end thereof with an outer lateral periphery larger in diameter than the outer surface of the inner catheter. A passageway is formed between said outer catheter and said inner catheter. A connector hub assembly, connected to the proximal end of the outer catheter and couplable to a supply of oxygen, allows for oxygen insufflation to take place during the bronchoalveolar lavage procedure. The proximal surface of the tip between the outer lateral periphery and the outer surface of the inner catheter is capable of sealingly engaging the distal end of the outer catheter. In this condition the pair of catheters can be advanced through the upper respiratory system of the patient without contaminating the outer surface of the inner catheter. Thereafter the inner catheter is advanced relative to the outer catheter into a wedging position in a bronchiole of the patient. In one embodiment, the inner catheter is provided with a selectively inflatable cuff by which to engage the walls of a bronchiole of the patient.

公开(公告)号：WO1992010132A1

公开(公告)日：1992-06-25

申请号：PCT/US1991008511

申请日：1991-11-14

Applicant: LUXTRON CORPORATION

Inventor： LUXTRON CORPORATION ,  JENSEN, Earl, M. ,  SUN, Mei, H. ,  VECHT, David, L. ,  MELEN, Robert, E.

IPC: A61B05/00

CPC classification number: G01K11/3213

Abstract: A luminescence-based integrated optical (11) and electronic system (29, 37, 51, 55, 59) for measuring temperature or some other parameter from the decay time of a luminescent sensor (25) is disclosed. A high bandwidth, low noise amplifier (31) applies a detected decaying luminescent signal to a digital system (29, 37, 51) that acquires that signal and processes it in order to determine its decay time characteristics that are related to temperature or another parameter being measured. The digital signal processing includes use of a digital curve-fitting technique. A preferred luminescent material for temperature measurement is a chromium-doped yttrium gallium garnet material. The entire optical and electronic portions of the measuring system can be accommodated on a small single circuit card (131).

公开(公告)号：WO1992003965A1

公开(公告)日：1992-03-19

申请号：PCT/CA1991000305

申请日：1991-08-28

Applicant: CADELL, Theodore, E. ,  MacHATTIE, Donald, B.

IPC: A61B05/00

CPC classification number: A61B5/6843 ,  A61B5/14552

Abstract: A finger receptor is used with a non-invasive monitoring device to determine non-invasively the concentration of known constituents in blood or tissue. The receptor has a channel for receiving a finger of a user. The channel has a light entrance and a light exit so that light can be passed from a light source through a finger located in the channel in a direction generally normal to the finger. Extraneous light is excluded and the finger is held in position by a spring-mounted roller. The receptor has sensing means to determine when a finger has been properly positioned in the channel. Previous devices are not capable of achieving repeatable results to a sufficient degree to replace invasive methods of testing.

Abstract translation: 手指受体与非侵入性监测装置一起使用以非侵入性地确定血液或组织中已知成分的浓度。 受体具有用于接收用户手指的通道。 通道具有光入射和光出射，使得光可以从光源通过位于通道中的手指沿着通常垂直于手指的方向通过。 外部光被排除，手指通过弹簧安装的滚轮固定在位。 受体具有感测装置，用于确定手指何时在通道中被正确定位。 以前的设备不能够在足够的程度上实现可重复的结果来代替侵入性测试方法。

公开(公告)号：WO1991018548A1

公开(公告)日：1991-12-12

申请号：PCT/DK1991000152

申请日：1991-06-06

Applicant: CLIFT, Vaughan

IPC: A61B05/00

CPC classification number: A61B5/1459 ,  A61B5/14532 ,  A61B5/6848 ,  G01N21/1702 ,  G01N21/314 ,  G01N21/35 ,  G01N21/552 ,  G01N21/553

Abstract: The concentration of a substance, especially glucose, in the blood is measured in vivo by applying to the skin two wavelengths of infrared light and measuring the difference in the absorption of the two wavelengths, preferably in the range of 3-10 mu m, one being a sample wavelength at which the substance shows a specific absorption and the other being a reference wavelength at which the substance shows no specific absorption. Simultaneously the concentrations of interfering components are measured in the same way and the result for the substance is corrected with regard to the measured concentrations of interfering components. Infrared light is transmitted through optical fibres (10, 10a) to a detector having two chambers (15, 15a), a sample wavelength to one chamber (15) and a reference wavelength to the other (15a), and a transducer (14) between the chambers measures the difference in the pressures induced in the respective chambers when the tissue beneath the chambers is heated by absorption of the infrared light transmitted to it.

Abstract translation: 血液中物质，特别是葡萄糖的浓度通过向皮肤施加两个波长的红外光并测量两个波长的吸收差，优选在3-10μm范围内，一个 是物质显示特定吸收的样品波长，另一个是物质不显示特定吸收的参考波长。 同时，以相同的方式测量干扰成分的浓度，并且对于测量的干扰成分的浓度校正该物质的结果。 红外光通过光纤（10,10a）传输到具有两个腔室（15,15a）的检测器，一个腔室（15）的样品波长和另一个腔室（15a）的参考波长的探测器和一个换能器（14） 在室之间，当通过吸收传递到其的红外光的吸收来加热腔室下面的组织时，两个室之间的压力差异可以测量各个腔室中的压力差。

公开(公告)号：WO1991012766A1

公开(公告)日：1991-09-05

申请号：PCT/US1991001239

申请日：1991-02-22

Applicant: THE GENERAL HOSPITAL CORPORATION

Inventor： THE GENERAL HOSPITAL CORPORATION ,  ANDERSON, Richard, Rox ,  GREEN, Howard, A. ,  NISHIOKA, Norman, S. ,  BUA, Dominic

IPC: A61B05/00

CPC classification number: A61B5/445 ,  A61B5/0071 ,  A61B18/20 ,  A61F2/105

Abstract: A method for distinguishing between a full thickness and a partial thickness skin burn in a patient having a skin burn. The method includes administering a fluorescent compound, which is excited by infrared light, to the patient to cause the compound to enter one or more capillaries below and adjacent the skin burn. The compound is then excited with infrared light, and the amount of fluorescence of the compound caused by the infrared light detected at the skin burn and at unburned skin adjacent the skin burn. The ratio of fluorescence detected at the skin burn and at the unburned skin is an indication of the thickness of the skin burn, e.g., a ratio of less than 0.4 indicates a full thickness skin burn.