公开(公告)号：WO1993010705A1

公开(公告)日：1993-06-10

申请号：PCT/US1991008941

申请日：1991-11-27

Applicant: INNERSPACE, INC.

Inventor： INNERSPACE, INC. ,  BECKMAN, Bruce

IPC: A61B05/02

CPC classification number: A61B5/14553 ,  A61B5/031

Abstract: A catheter assembly for measuring a fluid pressure in a body cavity includes an optical converter (39) responsive to an electrical power source for energizing a light-emitting diode (45) which has drift characteristics which vary in response to temperature. An optical sensor (72) is adapted to receive the light from the light-emitting diode and to provide a measurement signal indicative of the fluid pressure in the cavity. This measurement signal has undesirable characteristics related to the thermal drift characteristics of the diode. A detection circuit (93, 109) detects the measurement signal and provides an output signal indicative of fluid pressure in the cavity. A special filter (63) is included in this detection circuit which has optical characteristics that substantially offset the undesirable characteristics of the measurement signal, so that the output signal is substantially independent of the temperature of the diode. A power conversion (36) circuit enables the assembly to be energized by an excitation voltage which is provided in several different forms by various monitors.

Abstract translation: 用于测量体腔内的流体压力的导管组件包括响应于电源的光学转换器（39），用于激励具有随温度变化的漂移特性的发光二极管（45）。 光学传感器（72）适于接收来自发光二极管的光并提供指示空腔中的流体压力的测量信号。 该测量信号具有与二极管的热漂移特性相关的不期望的特性。 检测电路（93,109）检测测量信号，并提供指示空腔中的流体压力的输出信号。 该检测电路中包括一个特殊的滤波器（63），其具有基本上抵消测量信号的不良特性的光学特性，使得输出信号基本上与二极管的温度无关。 电源转换（36）电路使得组件能够被各种监视器以几种不同形式提供的激励电压激励。

公开(公告)号：WO1996004846A1

公开(公告)日：1996-02-22

申请号：PCT/US1995010014

申请日：1995-08-07

Applicant: INNERSPACE, INC.

Inventor： INNERSPACE, INC. ,  BOBO, Donald, E.

IPC: A61B05/103

CPC classification number: A61B5/031 ,  A61B5/0215 ,  A61B5/035 ,  A61M2025/0003

Abstract: A gas column pressure-measuring catheter (12) which is insertable into a mammalian body for purposes of transmitting pressure changes from a location within the mammalian body to a pressure sensor (14) which is either incorporated into, or connected to, the catheter (12). In a preferred embodiment, the gas column pressure-measuring catheter (12) comprises an elongate catheter body (20) having a gas-filled lumen (22) extending longitudinally therethrough, and a gas-filled membrane-walled chamber (38, 40) positioned on the catheter body in communication with the gas-filled lumen such that pressure changes exerted against the outer surface of the membrane-walled chamber will result in the transmission of pressure changes through the gas-filled catheter lumen (22). The gas-filled membrane-walled chamber may be located on the side wall of the catheter body (20) or on the distal end of the catheter body (20).

Abstract translation: 一种气体柱压力测量导管（12），其可插入到哺乳动物体内，用于将压力变化从哺乳动物体内的位置传递到压力传感器（14），所述压力传感器（14）被并入或连接到导管 12）。 在优选实施例中，气柱压力测量导管（12）包括细长的导管主体（20），其具有纵向穿过其中延伸的气体填充腔（22）和气体充填膜壁室（38,40） 定位在与气体填充的内腔连通的导管主体上，使得对膜壁室的外表面施加的压力变化将导致压力变化通过充气导管腔（22）传递。 充气的膜壁室可以位于导管主体（20）的侧壁上或导管主体（20）的远端上。

公开(公告)号：WO1992019150A1

公开(公告)日：1992-11-12

申请号：PCT/US1992003620

申请日：1992-04-29

Applicant: INNERSPACE, INC.

Inventor： INNERSPACE, INC. ,  FRUGARD, Gary, G. ,  BECKMAN, Ronald, B. ,  BOBO, Donald, E.

IPC: A61B05/00

CPC classification number: A61B5/14542 ,  A61B5/1473 ,  A61B5/6848

Abstract: A probe (10) adapted for direct insertion into the tissue of a patient, includes a needle (21) having walls defining an interior lumen (38) and a closed tip with a generally conical configuration. At least one sensor (14) capable of measuring a particular physiological parameter is disposed in the lumen. At least one window (41) is formed in the needle wall (36) along a path between the tissue and the sensor. A filler material (52) disposed along the path inhibits the passage of air or blood while facilitating transmission of the particular physiological parameter of interest such as oxygen, carbon dioxide, pH, and pressure.

Abstract translation: 适于直接插入患者组织的探针（10）包括具有限定内腔（38）的壁和具有大致圆锥形构造的封闭尖端的针（21）。 能够测量特定生理参数的至少一个传感器（14）设置在内腔中。 至少一个窗口（41）沿着组织和传感器之间的路径在针壁（36）中形成。 沿着路径设置的填充材料（52）抑制空气或血液的通过，同时促进感兴趣的特定生理参数如氧气，二氧化碳，pH和压力的传递。

公开(公告)号：WO1992005441A1

公开(公告)日：1992-04-02

申请号：PCT/US1991006716

申请日：1991-09-17

Applicant: INNERSPACE, INC.

Inventor： INNERSPACE, INC. ,  OVIATT, Henry, W., Jr. ,  REICH, Cary, J. ,  MOREHEAD, Steven, R. ,  LUSK, James, R.

IPC: G01N33/00

CPC classification number: G01N21/7703 ,  G01N21/6428 ,  G01N2021/6432 ,  G01N2021/6434 ,  G01N2021/772 ,  G01N2021/773 ,  G01N2021/7786

Abstract: A dye matrix is provided for use in an optical sensor. In the preferred embodiment sufficient of a gas-sensitive organometallic aromatic-containing fluorescent dye is dissolved in an organosilane polymer permeable to the gas to measure concentrations of oxygen or other gases in bodily tissue. The polymer contains sufficient aromatic substituents to prevent the dye from crystallizing and sufficient crosslinker to prevent an increase in turbidity in the dye matrix in an aqueous environment for up to 72 hours. A reference fluorescent dye can also be dissolved in the dye matrix to aid in screening out the "noise" introduced by muscle movement when the sensor is used in a tissue probe, such as a tissue oxygen probe.

Abstract translation: 提供用于光学传感器的染料基质。 在优选的实施方案中，足够的气敏有机金属芳族化合物的荧光染料溶解在可渗透气体的有机硅烷聚合物中，以测量身体组织中的氧气或其它气体的浓度。 聚合物含有足够的芳族取代基以防止染料结晶和充分的交联剂，以防止染料基质在水性环境中的浊度增加达72小时。 参考荧光染料也可以溶解在染料基质中，以帮助筛选当组织探针如组织氧探针中使用传感器时由肌肉运动引入的“噪音”。

公开(公告)号：WO1996010357A1

公开(公告)日：1996-04-11

申请号：PCT/US1995012132

申请日：1995-09-25

Applicant: INNERSPACE, INC. ,  BOBO, Donald, E., Jr. ,  DOUPE, Thomas, H.

Inventor： INNERSPACE, INC.

IPC: A61B05/00

CPC classification number: A61B5/02233 ,  A61B5/021

Abstract: An improved blood pressure monitoring pad assembly (40, 100) and method of use are disclosed herein. In accordance with a first feature of the pad assembly (40, 100) a release mechanism (66, 144) is used to prevent the pad assembly (40, 100) from detaching from the skin as the bladder is pressurized. In accordance with a second feature, the pad assembly (40, 100) includes a flexible cover (44) movably connected with a flexible base assembly (42). In accordance with a third feature, the pad assembly (40, 100) incorporates a biflex member (124).

Abstract translation: 本文公开了一种改进的血压监测垫组件（40,100）及其使用方法。 根据衬垫组件（40,100）的第一特征，使用释放机构（66,144）来防止衬垫组件（40,100）在气囊被加压时从皮肤脱离。 根据第二特征，垫组件（40,100）包括与柔性基座组件（42）可移动地连接的柔性盖（44）。 根据第三特征，衬垫组件（40,100）包括双股架构件（124）。