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    METHOD OF AND APPARATUS FOR GENERATING SIGNAL FOR INTRODUCTION OF CHEMICAL REACTIVE COMPONENT INTO CHEMICAL ANALYSIS APPARATUS
    12.
    发明专利
    METHOD OF AND APPARATUS FOR GENERATING SIGNAL FOR INTRODUCTION OF CHEMICAL REACTIVE COMPONENT INTO CHEMICAL ANALYSIS APPARATUS 失效

    公开(公告)号：JPS52149195A

    公开(公告)日：1977-12-12

    申请号：JP6341077

    申请日：1977-06-01

    Applicant: BECKMAN INSTRUMENTS INC

    Inventor： ROBAATO JIEI ANDAASON

    IPC: G01N21/76 ,  G01N21/64 ,  G01N21/78 ,  G01N31/00 ,  G01N33/53 ,  G01N33/536 ,  G01N33/58 ,  G01N35/00

    Abstract: A system for chemically analyzing antigens or antibodies by initiating an antigen-antibody reaction in a reaction zone and measuring the light scattered by a precipitate produced by the reaction to determine the antigen or antibody concentration. In order to signal the start of the reaction, a fluorescent tagging substance is included with at least the last antigen or antibody reaction component introduced into the reaction zone. The fluorescent tagging substance does not enter into the antigen-antibody reaction and is selected to emit light in a bandwidth spectrally separated from the light scattered by the precipitate. The reaction zone is monitored for the presence of the tagging substance, and when the substance is detected a trigger signal is generated to signal the start of the reaction. By including a tagging substance with each component of the reaction and by monitoring the reaction zone for the presence of each tagging substance, a trigger signal is generated only if each reaction component is present.

    15.
    发明专利
    失效

    公开(公告)号：JPS5814200B2

    公开(公告)日：1983-03-17

    申请号：JP5020678

    申请日：1978-04-28

    Applicant: BECKMAN INSTRUMENTS INC

    Inventor： KENESU JEI PIEERE ,  KEAAKONGU TSUNGU

    IPC: G01N33/535 ,  C12Q1/32 ,  C12Q1/54 ,  G01N31/00 ,  G01N33/66

    Abstract: The range of linearity of the kinetic method for the determination of glucose concentrations using a reagent of the type comprising a buffer, a pyridine coenzyme, and glucose dehydrogenase, is significantly increased when the buffer employed in the reagent has a pH of from about 7.9 to about 9.0.

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