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公开(公告)号:US20160299067A1
公开(公告)日:2016-10-13
申请号:US15183969
申请日:2016-06-16
Applicant: BacterioScan LTD.
Inventor: Amnon Weichselbaum
CPC classification number: G01N21/51 , B01L3/50 , B01L3/508 , B01L2300/04 , B01L2300/0809 , C12Q1/04 , C12Q1/06 , C12Q1/10 , C12Q1/18 , G01N21/03 , G01N21/49 , G01N33/4875 , G01N33/493 , G01N2015/0693 , G01N2021/0346 , G01N2021/0389 , G01N2021/513
Abstract: A method for detecting and counting particles suspended in fluids, such as bacteria suspended in urine, utilizing dynamic features of the suspended particles and employing light scattering measurements. The disclosed method is suitable for determining the susceptibility of bacteria to antibiotics. A cuvette for detecting bacteria in fluids, which is especially suited for the light scattering measurements, is provided.
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公开(公告)号:GB2432660A
公开(公告)日:2007-05-30
申请号:GB0615692
申请日:2006-08-08
Applicant: BACTERIOSCAN LTD
Inventor: WEICHSELBAUM AMNON , ZERDA JAIME DE LA
Abstract: A method for detecting and counting particles 12 suspended in fluids, such as bacteria suspended in urine, utilizing dynamic features of the suspended particles and employing light scattering measurements. The disclosed method is suitable for determining the susceptibility of bacteria to antibiotics. A cuvette 14 for detecting bacteria in fluids, which is especially suited for the light scattering measurements, is provided.
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公开(公告)号:US20200372976A1
公开(公告)日:2020-11-26
申请号:US16947655
申请日:2020-08-11
Applicant: BacterioScan LTD
Inventor: Dana A. Marshall , Theodore S. McMinn , Dan Vadim Regelman
Abstract: An optical measurement instrument is an integrated instrument that includes an optical cavity with a light source, a sample cuvette, and an optical sensor. The instrument can be used for taking measurements of organism concentration in one or more samples. Preferably, the instrument holds multiple, individually-loaded, independent fluid samples and determines bacteria concentration via a forward-scattering signal. The instrument can incorporate onboard incubation to promote bacterial growth in the samples such that, once a certain bacterial concentration is achieved, the higher concentration sample can be used with a mass spectrometer to identify the type of bacteria. The instrument and mass spectrometer can be a part of a network for medical diagnostic testing data where data is stored in a manner that is inherently untainted by patient identifiable information.
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16.
公开(公告)号:US20200290036A1
公开(公告)日:2020-09-17
申请号:US16887792
申请日:2020-05-29
Applicant: BacterioScan LTD
Inventor: Dana A. Marshall , Theodore S. McMinn , Dan Vadim Regelman
Abstract: The present invention is a cuvette assembly for use in optically measuring at least one characteristic of particles within a plurality of liquid samples. The cuvette assembly comprises a main body having internal walls and external walls, and a plurality of cuvettes within the main body at least partially being defined by the internal walls. Each of the plurality of cuvettes has a liquid-input chamber for receiving a respective one of the plurality of liquid samples, a filter, and an optical chamber for receiving a respective filtered liquid sample caused by passing the respective one of the plurality of liquid samples through the filter. Each of the optical chambers includes an entry window for allowing transmission of an input light beam through the filtered liquid sample and an exit window for transmitting a forward scatter signal caused by the particles within the filtered liquid sample.
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17.
公开(公告)号:US10233481B2
公开(公告)日:2019-03-19
申请号:US14959054
申请日:2015-12-04
Applicant: BacterioScan LTD
Inventor: Dana A. Marshall , Theodore S. McMinn , Dan Vadim Regelman
Abstract: An optical measurement instrument is an integrated instrument that includes an optical cavity with a light source, a sample cuvette, and an optical sensor. The light source and sensor are on a bench that is on a translational or rotational mechanical platform such that optical beam can be moved to multiple sample containers. The instrument can be used for taking measurements of organism concentration in multiple samples as a production tool for microbiology. Preferably, the instrument holds multiple, individually-loaded, independent fluid samples and determines bacteria concentration via a forward-scattering signal. The instrument can incorporate onboard incubation to promote bacterial growth in the samples during the test. In another aspect, the instrument can be a part of a network for medical diagnostic testing data where data is stored in a manner that is inherently untainted by patient identifiable information.
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公开(公告)号:US10006857B2
公开(公告)日:2018-06-26
申请号:US15005321
申请日:2016-01-25
Applicant: BacterioScan LTD
Inventor: Dana A. Marshall , Dan Vadim Regelman
CPC classification number: G01N21/51 , G01N21/0303 , G01N2021/513 , G01N2201/0231 , G01N2201/0415
Abstract: An instrument determines a concentration of bacteria in a plurality of fluid samples, and comprises a housing, a rotatable platform, a plurality of fluid containers, a light source, a sensor, and a motor. The rotatable platform is within the housing. The fluid containers are located on the rotatable platform. Each fluid container holds a corresponding one of the plurality of fluid samples, and has an input window and an output window. The light source provides an input beam for transmission into the input windows of the fluid containers and through the corresponding fluid samples. The input beam creates a forward-scatter signal associated with the concentration of bacteria. The motor rotates the rotatable platform so that the input beam sequentially passes through each fluid sample. A sensor within the housing detects the forward-scatter signal exiting from the output window associated with the fluid sample receiving the input beam.
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19.
公开(公告)号:US10668466B2
公开(公告)日:2020-06-02
申请号:US16050105
申请日:2018-07-31
Applicant: BacterioScan LTD
Inventor: Dana A. Marshall , Theodore S. McMinn , Dan Vadim Regelman
Abstract: The present invention is a cuvette assembly for use in optically measuring at least one characteristic of particles within a plurality of liquid samples. The cuvette assembly comprises a main body having internal walls and external walls, and a plurality of cuvettes within the main body at least partially being defined by the internal walls. Each of the plurality of cuvettes has a liquid-input chamber for receiving a respective one of the plurality of liquid samples, a filter, and an optical chamber for receiving a respective filtered liquid sample caused by passing the respective one of the plurality of liquid samples through the filter. Each of the optical chambers includes an entry window for allowing transmission of an input light beam through the filtered liquid sample and an exit window for transmitting a forward scatter signal caused by the particles within the filtered liquid sample.
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公开(公告)号:US20180313753A1
公开(公告)日:2018-11-01
申请号:US16013643
申请日:2018-06-20
Applicant: BacterioScan LTD
Inventor: Dana A. Marshall , Dan Vadim Regelman
CPC classification number: G01N21/51 , G01N21/0303 , G01N2021/513 , G01N2201/0231 , G01N2201/0415
Abstract: An instrument determines a concentration of bacteria in a plurality of fluid samples, and comprises a housing, a rotatable platform, a plurality of fluid containers, a light source, a sensor, and a motor. The rotatable platform is within the housing. The fluid containers are located on the rotatable platform. Each fluid container holds a corresponding one of the plurality of fluid samples, and has an input window and an output window. The light source provides an input beam for transmission into the input windows of the fluid containers and through the corresponding fluid samples. The input beam creates a forward-scatter signal associated with the concentration of bacteria. The motor rotates the rotatable platform so that the input beam sequentially passes through each fluid sample. A sensor within the housing detects the forward-scatter signal exiting from the output window associated with the fluid sample receiving the input beam.
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