Surfaced enhanced Raman spectroscopy substrates
    12.
    发明授权
    Surfaced enhanced Raman spectroscopy substrates 有权
    表面增强拉曼光谱基板

    公开(公告)号:US08427639B2

    公开(公告)日:2013-04-23

    申请号:US12437091

    申请日:2009-05-07

    CPC classification number: G01N21/658

    Abstract: Manufacturing a surface enhanced Raman spectroscopy (SERS) active structure includes exposing a substrate to produce an exposure pattern then etching the substrate based on the exposure pattern to produce a plurality of nanostructure cores having a plurality of sides extending from the substrate. Adjacent nanostructure cores are separated by core gaps. SERS active material is deposited onto the plurality of nanostructure cores producing a structure having gaps suitable for use in a SERS process.

    Abstract translation: 制造表面增强拉曼光谱(SERS)活性结构包括曝光衬底以产生曝光图案,然后基于曝光图案蚀刻衬底,以产生多个从衬底延伸的多个侧面的纳米结构芯。 相邻的纳米结构芯通过芯间隙分开。 SERS活性材料沉积到多个纳米结构芯上,产生具有适合用于SERS工艺的间隙的结构。

    Device and methods of detection of airborne agents
    13.
    发明授权
    Device and methods of detection of airborne agents 有权
    空气传播剂检测装置及方法

    公开(公告)号:US08247238B2

    公开(公告)日:2012-08-21

    申请号:US13217616

    申请日:2011-08-25

    Abstract: Provided are methods, devices and systems that utilize free-surface fluidics and SERS for analyte detection with high sensitivity and specificity. The molecules can be airborne agents, including but not limited to explosives, narcotics, hazardous chemicals, or other chemical species. The free-surface fluidic architecture is created using an open microchannel, and exhibits a large surface to volume ratio. The free-surface fluidic interface can filter interferent molecules, while concentrating airborne analyte molecules. The microchannel flow enables controlled aggregation of SERS-active probe particles in the flow, thereby enhancing the detector's sensitivity.

    Abstract translation: 提供了利用自由表面流体学和SERS用于具有高灵敏度和特异性的分析物检测的方法,装置和系统。 分子可以是空气传播剂,包括但不限于爆炸物,麻醉剂,危险化学品或其他化学物质。 自由表面流体结构使用开放的微通道产生,并且表现出大的表面与体积比。 自由表面流体界面可以过滤干扰分子,同时浓缩空气中的分析物。 微通道流动使SERS活性探针颗粒在流动中受控聚集,从而提高检测器的灵敏度。

    PLATFORM FOR CHEMICAL AND BIOLOGICAL SENSING BY SURFACE-ENHANCED RAMAN SPECTROSCOPY
    15.
    发明申请
    PLATFORM FOR CHEMICAL AND BIOLOGICAL SENSING BY SURFACE-ENHANCED RAMAN SPECTROSCOPY 有权
    通过表面增强拉曼光谱法进行化学和生物感测平台

    公开(公告)号:US20080174775A1

    公开(公告)日:2008-07-24

    申请号:US12018763

    申请日:2008-01-23

    CPC classification number: G01N21/658 Y10T428/24998

    Abstract: Methods of analysis, and compositions relating to such, to determine the presence or absence of an analyte in a sample utilizing a composite substrate which facilitates surface enhanced Raman spectroscopy through the use of ‘hot spots’ of the form ‘metal/analyte/metal’ are presented. Additionally, substrates which contain ‘hot spots’ of the form ‘metal/analyte/metal’ and substrates which facilitate the formation of ‘hot spots’ of the form ‘metal/analyte/metal’ are presented as well as methods for making these substrates.

    Abstract translation: 分析方法以及与此相关的组合物,通过使用“金属/分析物/金属”形式的“热点”来促进表面增强拉曼光谱,从而确定样品中存在或不存在分析物, 被呈现。 此外,还提出了包含“金属/分析物/金属”形式的“热点”和促进形成“金属/分析物/金属”形式的“热点”的基板的基板以及制造这些基板的方法 。

    Process of diamond growth from C.sub.70
    16.
    发明授权
    Process of diamond growth from C.sub.70 失效
    C70钻石生长过程

    公开(公告)号:US5614258A

    公开(公告)日:1997-03-25

    申请号:US391705

    申请日:1995-02-21

    CPC classification number: C30B23/00 C23C16/27 C30B25/00 C30B29/04

    Abstract: A method of growing diamond crystals in excess of 10 .mu.m in diameter from industrial diamond "seeds" having mean diameters of approximately 1.5 .mu.m is disclosed. The diamonds are grown by exposing the seed diamonds to C.sub.70 in the presence of reducing agents such as phosphorus or selenium in evacuated cells at moderate temperatures and pressures.

    Abstract translation: 公开了从具有平均直径约1.5μm的工业金刚石“种子”生长直径超过10μm的金刚石晶体的方法。 在中等温度和压力下,在真空的细胞中,在还原剂如磷或硒的存在下,将种子金刚石暴露于C70来生长钻石。

    Process for manufacture of quantum dot and quantum wire semiconductors
    17.
    发明授权
    Process for manufacture of quantum dot and quantum wire semiconductors 失效
    量子点和量子线半导体的制造工艺

    公开(公告)号:US5202290A

    公开(公告)日:1993-04-13

    申请号:US801404

    申请日:1991-12-02

    Inventor: Martin Moskovits

    Abstract: Quantum dot and quantum wire semiconductors in the nanosize range are produced by a process which utilizes a microporous aluminum oxide surface layer on an aluminum metal substrate as a template for the semiconducting material. The microporous surface layer is prepared by anodizing an aluminum substrate in an acid bath. Then a metal capable of forming a semiconductor compound is electrodeposited into the surface micropores, the oxide is partially or wholly etched away, and the deposited metal is reacted with a liquid or gaseous reagent to convert it chemically to a semiconducting compound. By the process of the invention, there are produced quantum dot or quantum wire semiconductors in the form of an array of substantially mutually parallel, substantially uniform-sized rods of semiconductor material protruding from an electrically conductive substrate, each rod having a diameter less than 100 nanometers.

    Abstract translation: 在纳米尺度范围内的量子点和量子线半导体是通过利用铝金属衬底上的微孔氧化铝表面层作为半导体材料的模板的方法产生的。 微孔表面层通过在酸浴中阳极氧化铝基材来制备。 然后将能够形成半导体化合物的金属电沉积到表面微孔中,氧化物被部分或全部蚀刻掉,并且沉积的金属与液体或气态试剂反应,以将其化学转化为半导体化合物。 通过本发明的方法,产生量子点或量子线半导体,其形式为基本上相互平行的,基本上均匀尺寸的半导体材料棒,从导电基底突出,每个棒的直径小于100 纳米。

    Highly Efficient Plamonic Devices, Molecule Detection Systems, and Methods of Making the Same
    18.
    发明申请
    Highly Efficient Plamonic Devices, Molecule Detection Systems, and Methods of Making the Same 审中-公开
    高效率Plamonic器件,分子检测系统及其制作方法

    公开(公告)号:US20120081703A1

    公开(公告)日:2012-04-05

    申请号:US13273105

    申请日:2011-10-13

    CPC classification number: G01N21/658

    Abstract: A plasmonic device has a plurality of nanostructures extending from a substrate. Each of the plurality of nanostructures preferably includes a core, a coating of intermediate material covering at least a portion of the core, and a coating of a plasmonic material. Devices are preferably manufactured using lithography to create the cores, and Plasma Enhanced Chemical Vapor Deposition (PECVD) to deposit the intermediate and/or plasmonic materials. Cores can be arranged in any suitable pattern, including one-dimensional or two-dimensional patterns. Devices can be used in airborne analyte detectors, in handheld roadside controlled substance detectors, in genome sequencing device, and in refraction detectors.

    Abstract translation: 等离子体激元器件具有从衬底延伸的多个纳米结构。 多个纳米结构中的每一个优选地包括芯,覆盖芯的至少一部分的中间材料的涂层和等离子体激元材料的涂层。 器件优选使用光刻制造以产生芯,以及等离子体增强化学气相沉积(PECVD)以沉积中间和/或等离子体激元材料。 芯可以以任何合适的图案布置,包括一维或二维图案。 设备可用于机载分析物检测器,手持路旁控制物质检测器,基因组测序装置和折射检测器中。

    Device and methods of detection of airborne agents
    19.
    发明授权
    Device and methods of detection of airborne agents 有权
    空气传播剂检测装置及方法

    公开(公告)号:US08017408B2

    公开(公告)日:2011-09-13

    申请号:US12597742

    申请日:2008-04-25

    Abstract: Provided are methods, devices and systems that utilize free-surface fluidics and SERS for analyte detection with high sensitivity and specificity. The molecules can be airborne agents, including but not limited to explosives, narcotics, hazardous chemicals, or other chemical species. The free-surface fluidic architecture is created using an open microchannel, and exhibits a large surface to volume ratio. The free-surface fluidic interface can filter interferent molecules, while concentrating airborne analyte molecules. The microchannel flow enables controlled aggregation of SERS-active probe particles in the flow, thereby enhancing the detector's sensitivity.

    Abstract translation: 提供了利用自由表面流体学和SERS用于具有高灵敏度和特异性的分析物检测的方法,装置和系统。 分子可以是空气传播剂,包括但不限于爆炸物,麻醉剂,危险化学品或其他化学物质。 自由表面流体结构使用开放的微通道产生,并且表现出大的表面与体积比。 自由表面流体界面可以过滤干扰分子,同时浓缩空气中的分析物。 微通道流动使SERS活性探针颗粒在流动中受控聚集,从而提高检测器的灵敏度。

    Platform for chemical and biological sensing by surface-enhanced Raman spectroscopy
    20.
    发明授权
    Platform for chemical and biological sensing by surface-enhanced Raman spectroscopy 有权
    通过表面增强拉曼光谱技术进行化学和生物传感平台

    公开(公告)号:US07898658B2

    公开(公告)日:2011-03-01

    申请号:US12018763

    申请日:2008-01-23

    CPC classification number: G01N21/658 Y10T428/24998

    Abstract: Methods of analysis, and compositions relating to such, to determine the presence or absence of an analyte in a sample utilizing a composite substrate which facilitates surface enhanced Raman spectroscopy through the use of ‘hot spots’ of the form ‘metal/analyte/metal’ are presented. Additionally, substrates which contain ‘hot spots’ of the form ‘metal/analyte/metal’ and substrates which facilitate the formation of ‘hot spots’ of the form ‘metal/analyte/metal’ are presented as well as methods for making these substrates.

    Abstract translation: 分析方法以及与此相关的组合物,通过使用“金属/分析物/金属”形式的“热点”来促进表面增强拉曼光谱,从而确定样品中存在或不存在分析物, 被呈现。 此外,还提出了包含“金属/分析物/金属”形式的“热点”和促进形成“金属/分析物/金属”形式的“热点”的基板的基板以及制造这些基板的方法 。

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