公开(公告)号：US20230166284A1

公开(公告)日：2023-06-01

申请号：US18161462

申请日：2023-01-30

Applicant: STAMFORD DEVICES LIMITED

Inventor： Michael AHERNE ,  Colga COYE ,  Philip SCANLON

IPC: B05B17/00

CPC classification number: B05B17/0646

Abstract: An aperture plate (1) is attached at its rim (203) to a support washer (3) by adhesive. Anchor grooves (204) having a zig-zag pattern in plan are machined in the lower surface of the rim (203 of the aperture plate before application of the adhesive. The grooves (204) extend out to the edge of the aperture plate (1). The anchor grooves have a depth in the range of 10 μm to 40 μm, and a width in the range of 20 μm to 150 μm, and an angular pitch in the range of 2.5° to 12.5°. Excellent bonding strength is achieved for long term reliable attachment in an environment of high frequency vibration and moisture and chemical corrosion.

公开(公告)号：US20230133932A1

公开(公告)日：2023-05-04

申请号：US18061564

申请日：2022-12-05

Applicant: STAMFORD DEVICES LIMITED

Inventor： Ronan MACLOUGHLIN ,  Shaun PORTER ,  Conor DUFFY ,  John POWER

IPC: A61M16/14 ,  A61M16/00 ,  A61M16/06 ,  A61M11/00

Abstract: A gas therapy system (1) has a flow line (3, 2), a coupler (6) to a gas source, and an aerosol generator (4) for aerosol delivery, and a patient interface such as a nasal interface (2). A controller (10) is configured to modulate gas flow and aerosol delivery in real time. The controller changes gas flow rate and dynamically reduces aerosol delivery during upper gas flow rates such as 60 LPM, and activates aerosol delivery during lower gas flow rates of for example 10 LPM. The control may also include sensors to detect breathing, so that there is a bias towards increased aerosol delivery during inhalation in addition to during lower level gas flow.

公开(公告)号：US11534570B2

公开(公告)日：2022-12-27

申请号：US16621560

申请日：2018-07-03

Applicant: STAMFORD DEVICES LIMITED

Inventor： Ronan MacLoughlin ,  Shaun Porter ,  Conor Duffy ,  John Power

IPC: A61M16/14 ,  A61M16/00 ,  A61M16/06 ,  A61M11/00 ,  A61M16/16

Abstract: A gas therapy system (1) has a flow line (3, 2), a coupler (6) to a gas source, and an aerosol generator (4) for aerosol delivery, and a patient interface such as a nasal interface (2). A controller (10) is configured to modulate gas flow and aerosol delivery in real time. The controller changes gas flow rate and dynamically reduces aerosol delivery during upper gas flow rates such as 60 LPM, and activates aerosol delivery during lower gas flow rates of for example 10 LPM. The control may also include sensors to detect breathing, so that there is a bias towards increased aerosol delivery during inhalation in addition to during lower level gas flow.

公开(公告)号：US11433189B2

公开(公告)日：2022-09-06

申请号：US16853039

申请日：2020-04-20

Applicant: Stamford Devices Limited

Inventor： Patrick Power

IPC: A61M11/02 ,  A61M11/00 ,  A61M11/06 ,  A61M16/16 ,  A61M16/00

Abstract: An aerosol delivery system has a nebulizer and a humidifier providing a gas flow to the nebulizer. A controller varies humidity level of the gas flow to the nebulizer so that if the nebulizer is not operating it has about 100% humidity and it is operating the value is less to allow for the humidification effect of the nebulizer. The control may be achieved by dynamically varying proportions of flow through a dry branch and a humidification branch.

公开(公告)号：US20220016365A1

公开(公告)日：2022-01-20

申请号：US17371412

申请日：2021-07-09

Applicant: Stamford Devices Limited

Inventor： John POWER ,  Ronan MacLOUGHLIN ,  Michael CASEY ,  Conor DUFFY ,  Aidan DUFFY

IPC: A61M15/00

Abstract: A dispensing apparatus is for use by users to take a chamber, fill the chamber with an aerosolized vaccine or other medicament, and dispose of used chambers. A display provides instructions to encourage prompt inhalation by the user from a dispensed and filled chamber. The apparatus allows very fast administration of vaccines to large numbers of people. The aerosol dispenser apparatus detects the chamber is in correct position and delivers a pre-determined dose of aerosol. Once the dose is delivered a visual and/or audible indicator informs the user that the chamber is filled and that they can take the inhalation. The single dose aerosol chamber is optimized for efficient administration of an aerosol.

公开(公告)号：US20220008672A1

公开(公告)日：2022-01-13

申请号：US17293203

申请日：2018-12-06

Applicant: STAMFORD DEVICES LIMITED

Inventor： Stefan KERN

IPC: A61M16/08 ,  A61M16/04

Abstract: A coupling part with integrated aerosol generator for use in a breathing circuit, comprising a housing (10) enclosing a cavity (V), having a first opening at a first end prepared for direct or indirect connection to a ventilator, a second opening at a second end, which is suitable for direct or indirect connection to a patient line or an endotracheal tube, wherein an aerosol generator (20) is integrated in one side of the housing and is suitable for delivering an aerosolised liquid, in particular a medicament.

公开(公告)号：US20210308387A1

公开(公告)日：2021-10-07

申请号：US17350562

申请日：2021-06-17

Applicant: Stamford Devices Limited

Inventor： Joseph GREHAN ,  Niall Smith

IPC: A61M11/00 ,  G01N29/22 ,  G01N29/42 ,  B05B17/00 ,  B05B17/06 ,  B06B1/02 ,  B05B15/14 ,  G16H20/10 ,  G16H20/13

Abstract: A nebulizer has an aperture plate, a mounting, an actuator, and an aperture plate drive circuit (2-4). A controller measures an electrical drive parameter at each of a plurality of measuring points, each measuring point having a drive frequency; and based on the values of the parameter at the measuring points makes a determination of optimum drive frequency and also an end-of-dose prediction. The controller performs a short scan at regular sub-second intervals at which drive current is measured at two measuring points with different drive frequencies. According to drive parameter measurements at these points the controller determines if a full scan sweeping across a larger number of measuring points should be performed. The full scan provides the optimum drive frequency for the device and also an end of dose indication.

公开(公告)号：US20200276607A1

公开(公告)日：2020-09-03

申请号：US16756204

申请日：2018-11-27

Applicant: STAMFORD DEVICES LIMITED

Inventor： Michael AHERNE ,  Colga COYE ,  Philip SCANLON

IPC: B05B17/00

Abstract: An aperture plate (1) is attached at its rim (203) to a support washer (3) by adhesive. Anchor grooves (204) having a zig-zag pattern in plan are machined in the lower surface of the rim (203 of the aperture plate before application of the adhesive. The grooves (204) extend out to the edge of the aperture plate (1). The anchor grooves have a depth in the range of 10 μm to 40 μm, and a width in the range of 20 μm to 150 μm, and an angular pitch in the range of 2.5° to 12.5°. Excellent bonding strength is achieved for long term reliable attachment in an environment of high frequency vibration and moisture and chemical corrosion.

公开(公告)号：US10399109B2

公开(公告)日：2019-09-03

申请号：US15476461

申请日：2017-03-31

Applicant: Stamford Devices Limited

Inventor： Brendan Hogan ,  Kieran Hyland ,  Anthony Redmond

IPC: A61M11/00 ,  A61M15/00 ,  B05B17/00

Abstract: An aerosol generator (100) has a vibratable plate (1) with apertures therein and an annular piezo (2) which causes movement of the vibratable plate (1). An annular support member (3) supports the piezo (2) and the vibratable plate (1). A first electrical power conducting pin (10) engages directly with a first, top, surface of the piezo (2). A second electrical power conducting pin (11) indirectly conducts electrical power to a second surface of the piezo (2), by contacting an extension tab (103) of the support member (20), also on its top side. There is a film of cured epoxy adhesive on the tab (103), providing excellent gripping force between the pin (11) and the support (3). The aerosol generator (100) avoids need for soldered joints for electrical contact, and the pins are conveniently mounted parallel to each on the on the same lateral and top side of the piezo and support member. The pins may have multi-point tips (50) for particularly effective electrical contact.

公开(公告)号：US20190210044A1

公开(公告)日：2019-07-11

申请号：US16358338

申请日：2019-03-19

Applicant: Stamford Devices Limited

Inventor： Brendan Hogan ,  Hong Xu

IPC: B05B1/02 ,  B05B17/06 ,  B05B17/00 ,  C25D7/04 ,  C25D1/08

CPC classification number: B05B1/02 ,  A61M11/005 ,  A61M15/0085 ,  A61M2207/00 ,  B05B17/0638 ,  B05B17/0653 ,  C25D1/08 ,  C25D7/04

Abstract: An aperture plate is manufactured by plating metal around a mask of resist columns having a desired size, pitch, and profile, which yields a wafer about 60 μm thickness. This is approximately the full desired target aperture plate thickness. The plating is continued so that the metal overlies the top surfaces of the columns until the desired apertures are achieved. This needs only one masking/plating cycle to achieve the desired plate thickness. Also, the plate has passageways formed beneath the apertures, formed as an integral part of the method, by mask material removal. These are suitable for entrainment of aerosolized droplets exiting the apertures.