公开(公告)号：US12290637B2

公开(公告)日：2025-05-06

申请号：US18061564

申请日：2022-12-05

Applicant: STAMFORD DEVICES LIMITED

Inventor： Ronan MacLoughlin ,  Shaun Porter ,  Conor Duffy ,  John Power

IPC: A61M16/14 ,  A61M11/00 ,  A61M11/02 ,  A61M16/00 ,  A61M16/06 ,  A61M16/16

Abstract: A gas therapy system (1) has a flow line (3, 2), a coupler (6) to a gas source, and an aerosol generator (4) for aerosol delivery, and a patient interface such as a nasal interface (2). A controller (10) is configured to modulate gas flow and aerosol delivery in real time. The controller changes gas flow rate and dynamically reduces aerosol delivery during upper gas flow rates such as 60 LPM, and activates aerosol delivery during lower gas flow rates of for example 10 LPM. The control may also include sensors to detect breathing, so that there is a bias towards increased aerosol delivery during inhalation in addition to during lower level gas flow.

公开(公告)号：US11833310B2

公开(公告)日：2023-12-05

申请号：US16750507

申请日：2020-01-23

Applicant: Stamford Devices Limited

Inventor： Ronan MacLoughlin ,  Niall Smith

IPC: A61M16/08 ,  A61M16/06 ,  A61M16/16 ,  A61M16/20 ,  A61M11/00 ,  A61M15/08 ,  A61M16/14 ,  A61M16/10 ,  A61M16/00

CPC classification number: A61M16/16 ,  A61M11/00 ,  A61M15/08 ,  A61M16/0666 ,  A61M16/0833 ,  A61M16/0866 ,  A61M16/0875 ,  A61M16/1095 ,  A61M16/14 ,  A61M16/202 ,  A61M2016/0018 ,  A61M2016/0027 ,  A61M2016/0033 ,  A61M2016/0036 ,  A61M2205/33 ,  A61M2205/3334

Abstract: A high flow nasal therapy system (1) has a gas supply (2), a nebulizer (12), and a nasal interface (7). There are two branches (11, 10) and a valve (6) linked with the controller, the branches including a first branch (11) for delivery of aerosol and a second branch (10) for delivery of non-aerosolized gas. The controller controls delivery into the branches (11, 10), in which flow is unidirectional in the first and second branches, from the gas supply towards the nasal interface. The first branch (11) includes the nebulizer (12) and a line configured to store a bolus of aerosol during flow through the second branch (10). The valve (6) comprises a Y-junction between the gas inlet on one side and the branches on the other side.

公开(公告)号：US11534570B2

公开(公告)日：2022-12-27

申请号：US16621560

申请日：2018-07-03

Applicant: STAMFORD DEVICES LIMITED

Inventor： Ronan MacLoughlin ,  Shaun Porter ,  Conor Duffy ,  John Power

IPC: A61M16/14 ,  A61M16/00 ,  A61M16/06 ,  A61M11/00 ,  A61M16/16

Abstract: A gas therapy system (1) has a flow line (3, 2), a coupler (6) to a gas source, and an aerosol generator (4) for aerosol delivery, and a patient interface such as a nasal interface (2). A controller (10) is configured to modulate gas flow and aerosol delivery in real time. The controller changes gas flow rate and dynamically reduces aerosol delivery during upper gas flow rates such as 60 LPM, and activates aerosol delivery during lower gas flow rates of for example 10 LPM. The control may also include sensors to detect breathing, so that there is a bias towards increased aerosol delivery during inhalation in addition to during lower level gas flow.

公开(公告)号：US12138382B2

公开(公告)日：2024-11-12

申请号：US17371412

申请日：2021-07-09

Applicant: Stamford Devices Limited

Inventor： John Power ,  Ronan MacLoughlin ,  Michael Casey ,  Conor Duffy ,  Aidan Duffy

IPC: A61M11/04 ,  A61M11/00 ,  A61M15/00 ,  B67D7/02 ,  G07F7/06 ,  G07F13/02 ,  G07F17/00 ,  G16H20/13 ,  G16H40/63

Abstract: A dispensing apparatus is for use by users to take a chamber, fill the chamber with an aerosolized vaccine or other medicament, and dispose of used chambers. A display provides instructions to encourage prompt inhalation by the user from a dispensed and filled chamber. The apparatus allows very fast administration of vaccines to large numbers of people. The aerosol dispenser apparatus detects the chamber is in correct position and delivers a pre-determined dose of aerosol. Once the dose is delivered a visual and/or audible indicator informs the user that the chamber is filled and that they can take the inhalation. The single dose aerosol chamber is optimized for efficient administration of an aerosol.

公开(公告)号：US10518288B2

公开(公告)日：2019-12-31

申请号：US15578923

申请日：2016-06-10

Applicant: Stamford Devices Limited

Inventor： Ronan MacLoughlin ,  Conor Duffy ,  Brendan Hogan ,  Patrick Martin Kelly

IPC: B05B17/00 ,  A61M11/00

Abstract: A method for aerosolising a liquid comprises the steps of: —providing an aperture plate having at least 100 outlet holes per mm2; delivering liquid to the aperture plate; and vibrating the aperture plate to produce an aerosol. The viscosity of the liquid is in the range of from 1 to 15 cP and the surface tension of the liquid is in the range of from 72 to 0.5 mN/m. The output rate of the generated aerosol is greater than 0.01 mL/min.