公开(公告)号：WO2014017915A3

公开(公告)日：2014-06-12

申请号：PCT/NL2013050562

申请日：2013-07-26

Applicant: UNIV UTRECHT HOLDING BV ,  STICHTING TECH WETENSCHAPP

Inventor： PIETERS ROELOF JAN ,  MARTIN NATHANIEL ISAAC ,  BRANDERHORST HILBERT MARINUS ,  KOOIJ RAYMOND

IPC: C07D211/46 ,  A61K31/445 ,  A61P3/00

CPC classification number: C07D211/46 ,  Y02P20/55

Abstract: The invention relates to novel urea and guanidinium derivatives of deoxynojirimycin and related iminosugars, wherein the ring nitrogen in the iminosugars is derivatised, methods for the preparation urea and guanidinium derivatives of deoxynojirimycin, (protected) intermediates and the use of the urea and guanidinium derivatives of deoxynojirimycin in the modification of the activity of glycosidases and their use as a pharmaceutical. Where in is a 5, 6, 7 or 8-membered (saturated) nitrogen-containing cyclic compound; wherein X is O or NR7; wherein R1 is H or a straight or branched alkyl, cycloalkyl, alkenyl, alkynyl, alkoxyalkyl or aminoalkyl containing 1 -20 carbon atoms, an aryl, alkylaryl, heteroaryl, heteroalkyl, alkoxy(het)aryl containing 5-12 ring atoms, wherein R1 is optionally substituted with one o more -OH, -COOH, -CI, -F, -CF3, -OCF3, -O-C(=O)N-(alkyl)2; wherein R2 is H or a straight or branched alkyl, cycloalkyl, alkenyl, alkynyl, alkoxyalkyl or aminoalkyl containing 1 -12 carbon atoms, an aryl, alkylaryl, heteroaryl, heteroalkyl, alkoxy(het)aryl containing 5-12 ring atoms, wherein R1 is optionally substituted with one o more -OH, -COOH, -CI, -F, -CF3, -OCF3, -O-C(=O)N-(alkyl)2; wherein R3, R4, R5, R6 are independently H or a hydroxyl protecting group, wherein R7 is H, C1-C6 alkyl;

Abstract translation: 本发明涉及脱氧野尻霉素及相关亚氨基二糖的新型尿素和胍衍生物，其中亚氨基糖内的环氮被衍生化，制备脱氧野尻霉素的尿素和胍衍生物（被保护的）中间体的方法和使用尿素和胍衍生物 脱氧野尻霉素对糖苷酶活性的修饰及其用作药物。 其中in是5,6,7或8元（饱和）含氮环状化合物; 其中X是O或NR7; 其中R 1为H或含有1〜20个碳原子的直链或支链烷基，环烷基，烯基，炔基，烷氧基烷基或氨基烷基，芳基，烷基芳基，杂芳基，杂烷基，含有5-12个环原子的烷氧基（het） 任选被一个或多个-OH，-COOH，-CI，-F，-CF 3，-OCF 3，-OC（= O）N-（烷基）2取代; 其中R2是H或含有1-12个碳原子的直链或支链烷基，环烷基，烯基，炔基，烷氧基烷基或氨基烷基，芳基，烷基芳基，杂芳基，杂烷基，含有5-12个环原子的烷氧基（het） 任选被一个或多个-OH，-COOH，-CI，-F，-CF 3，-OCF 3，-OC（= O）N-（烷基）2取代; 其中R 3，R 4，R 5，R 6独立地是H或羟基保护基，其中R 7是H，C 1 -C 6烷基;

公开(公告)号：WO2009150526A3

公开(公告)日：2010-02-25

申请号：PCT/IB2009005935

申请日：2009-06-15

Applicant: UNIV LEIDEN ,  STICHTING TECH WETENSCHAPP ,  SPAINK HERMAN PIETER ,  SCHMIDT THOMAS ,  ORRIT MICHEL ALAIN GASTON JULI ,  KULZER FLORIAN MARKUS

Inventor： SPAINK HERMAN PIETER ,  SCHMIDT THOMAS ,  ORRIT MICHEL ALAIN GASTON JULIEN ,  KULZER FLORIAN MARKUS

IPC: G01N15/14 ,  G01N21/17

CPC classification number: G01N15/1468 ,  G01N15/1434 ,  G01N21/171 ,  G01N2015/1452 ,  G01N2021/1712

Abstract: A photothermal system for performing high throughput single particle detection, the system comprising: a first optical path for directing a probe laser beam (PB) and a heating laser beam (MHB) towards a target or sample area (62); and a second optical path for directing the probe laser beam from the sample to a detector for detecting phase changes (?F) induced in the probe beam (PB) by the photothermal effect due to local heating of the sample by the heating beam (MHB), wherein the first optical path includes one or more optical elements (60a, 60b) arranged to define a detection volume of more than 10 femtolitres.

Abstract translation: 一种用于执行高通量单粒子检测的光热系统，所述系统包括：用于将探针激光束（PB）和加热激光束（MHB）引向目标或样品区域（62）的第一光路; 以及第二光路，用于将探针激光束从样品引导到检测器，用于通过由加热束（MHB）对样品的局部加热的光热效应检测在探针束（PB）中感应的相变（ΔF） ），其中所述第一光路包括布置成限定超过10毫伏的检测体积的一个或多个光学元件（60a，60b）。

公开(公告)号：WO2006088370A3

公开(公告)日：2006-10-12

申请号：PCT/NL2006050029

申请日：2006-02-16

Applicant: STICHTING TECH WETENSCHAPP ,  DEBIJE MICHAEL G ,  BASTIAANSEN CEES W M ,  BROER DICK J ,  ESCUTI MICHAEL J ,  SANCHEZ CARLOS

Inventor： DEBIJE MICHAEL G ,  BASTIAANSEN CEES W M ,  BROER DICK J ,  ESCUTI MICHAEL J ,  SANCHEZ CARLOS

IPC: F24J2/06 ,  G02B6/00 ,  H01L31/055

CPC classification number: G02B6/001 ,  H01L31/055 ,  Y02E10/52

Abstract: A first aspect of the invention relates to a luminescent object comprising an aligned polymer that contains an oriented photoluminescent material, said aligned polymer having a pretilt angle of 10-90º. The luminescent object according to the present invention may advantageously be employed in luminescent solar concentrator systems as it enables highly efficient transportation of radiation emitted by the photoluminescent material following exposure to incident solar light. Another aspect of the invention concerns a photovoltaic device comprising an electromagnetic radiation collection medium containing the aforementioned luminescent object and a photovoltaic cell capable of converting optical radiation to electrical energy which is optically coupled to the luminescent object. Further aspects of the invention include a fluorescent light activated display and a room lighting system comprising the aforementioned luminescent object.

Abstract translation: 本发明的第一方面涉及一种发光物体，其包含含有定向光致发光材料的对准聚合物，所述对准的聚合物具有10-90°的预倾角。 根据本发明的发光物体可以有利地用于发光太阳能集中器系统中，因为它能够在暴露于入射的太阳光之后高效地传输由光致发光材料发射的辐射。 本发明的另一方面涉及一种光伏器件，其包括含有上述发光物体的电磁辐射收集介质和能够将光辐射转换成与发光物体光耦合的电能的光伏电池。 本发明的其它方面包括荧光灯活化显示器和包括上述发光物体的室内照明系统。

公开(公告)号：WO2006088369A3

公开(公告)日：2006-10-12

申请号：PCT/NL2006050028

申请日：2006-02-16

Applicant: STICHTING TECH WETENSCHAPP ,  DEBIJE MICHAEL G ,  BASTIAANSEN CEES W M ,  BROER DICK J ,  ESCUTI MICHAEL J ,  SANCHEZ CARLOS

Inventor： DEBIJE MICHAEL G ,  BASTIAANSEN CEES W M ,  BROER DICK J ,  ESCUTI MICHAEL J ,  SANCHEZ CARLOS

IPC: F24J2/06 ,  G02B6/00 ,  H01L31/055

CPC classification number: G02B6/001 ,  H01L31/055 ,  Y02E10/52

Abstract: A first aspect of the invention relates to a luminescent object comprising: a. a luminescent layer or core containing a photoluminescent material; and b. a wavelength-selective mirror; wherein the luminescent layer or luminescent core is optically coupled to the wavelength-selective mirror, said wavelength-selective mirror being at least 50% transparent to light absorbed by the photoluminescent material and at least 50% reflective to radiation that is emitted by the photoluminescent material. The luminescent object according to the present invention may advantageously be employed in luminescent solar concentrator systems as it enables highly efficient transportation of radiation emitted by the photoluminescent material fo llowing exposure to incident solar light. Another aspect of the invention concerns a photovoltaic device comprising an electromagnetic radiation collection medium containing the aforementioned luminescent object and a photovoltaic cell capable of converting optical radiation to electrical energy which is optically coupled to the luminescent object. Further aspects of the invention include a fluorescent light activated display and a room lighting system comprising the aforementioned luminescent object.

Abstract translation: 本发明的第一方面涉及一种发光物体，包括：a。 包含光致发光材料的发光层或芯; 和b。 波长选择镜; 其中所述发光层或发光芯光学耦合到所述波长选择镜，所述波长选择镜对于由所述光致发光材料吸收的光具有至少50％的透明度，并且至少50％反射到由所述光致发光材料发射的辐射 。 根据本发明的发光物体可以有利地用于发光太阳能集中器系统中，因为它能够高效地传输由曝光于入射太阳光的光致发光材料发射的辐射。 本发明的另一方面涉及一种光伏器件，其包括含有上述发光物体的电磁辐射收集介质和能够将光辐射转换成与发光物体光耦合的电能的光伏电池。 本发明的其它方面包括荧光灯活化显示器和包括上述发光物体的室内照明系统。

公开(公告)号：WO2006068481A2

公开(公告)日：2006-06-29

申请号：PCT/NL2005050058

申请日：2005-12-01

Applicant: STICHTING TECH WETENSCHAPP ,  SCHOUTEN ALEXANDER ,  VAN KAN JOHANNES ARNOLDUS LAUR

Inventor： SCHOUTEN ALEXANDER ,  VAN KAN JOHANNES ARNOLDUS LAUR

CPC classification number: A01N63/04 ,  C07K14/37 ,  G01N33/5097

Abstract: The present invention relates to necrosis and ethylene inducing proteins from Botrytis species and their use. Provided are also methods for determining the susceptibility of a plant's tissue to a necrosis and ethylene inducing protein and methods for selecting plants being resistant to one or more of these proteins and to Botrytis infection.

Abstract translation: 本发明涉及来自Botrytis物种的坏死和诱导乙烯的蛋白质及其用途。 还提供了用于确定植物组织对坏死和乙烯诱导蛋白的易感性的方法以及用于选择对这些蛋白质中的一种或多种和葡萄孢属感染具有抗性的植物的方法。

公开(公告)号：WO2004013642A3

公开(公告)日：2004-10-21

申请号：PCT/NL0300464

申请日：2003-06-23

Applicant: STICHTING TECH WETENSCHAPP ,  STEENNIS EVERT FREDERIK ,  WOUTERS PETRUS ARNOLDUS ANTONI ,  VAN DER WIELEN PETRUS CAROLINA ,  VEEN JEROEN

Inventor： STEENNIS EVERT FREDERIK ,  WOUTERS PETRUS ARNOLDUS ANTONI ,  VAN DER WIELEN PETRUS CAROLINA ,  VEEN JEROEN

IPC: H04B3/56 ,  G01R31/12 ,  G01R31/08

CPC classification number: H04B3/56 ,  H04B2203/5483 ,  H04B2203/5487

Abstract: The invention relates to a method for inputting an information signal into a power cable which is connected to a voltage supply and which comprises at least one or more conductors, a dielectric provided around the conductors and a conductive earth sheath arranged wholly or partially around the dielectric, the method comprising of inputting a pulse-like information signal at a first position via the earth sheath in order to produce a corresponding pulse-like information signal which is propagated to a second position in the dielectric of the power cable.

Abstract translation: 本发明涉及一种用于将信息信号输入到连接到电压源的电力电缆中的方法，该电力电缆包括至少一个或多个导体，围绕导体设置的电介质和全​​部或局部围绕电介质布置的导电接地护套 该方法包括通过接地护套在第一位置输入脉冲状信息信号，以便产生相应的脉冲状信息信号，其传播到电力电缆的电介质中的第二位置。

公开(公告)号：WO0186254A3

公开(公告)日：2002-04-11

申请号：PCT/NL0100365

申请日：2001-05-14

Applicant: STICHTING TECH WETENSCHAPP ,  CHMELA EMIL ,  BLOM MARKO THEODOOR ,  HEYDEN FRANCISCUS HERMANUS JOH ,  DEN BERG ALBERT VAN ,  GARDENIERS JOHANNES GERARDUS E ,  TIJSSEN ROBERT

Inventor： CHMELA EMIL ,  BLOM MARKO THEODOOR ,  VAN DER HEYDEN FRANCISCUS HERM ,  VAN DEN BERG ALBERT ,  GARDENIERS JOHANNES GERARDUS E ,  TIJSSEN ROBERT

IPC: A61B5/00 ,  G01N11/08

CPC classification number: A61B5/14532 ,  G01N11/08

Abstract: The present invention relates to a device suitable for measuring the viscosity of a fluid, which device comprises on all sides surrounded channels, and a membrane suitably connected to the channels for differential pressure measurement. According to the invention, the first channel is located in a first plane and the secondchannel in a second plane, which first plane and second plane are oriented substantially parallel in relation to each other, and the membrane is located in a plane substantially parallel to the first plane. This facilitates the device to be filled with liquid without the danger of the retention of air bubbles. The device can be used as an independent viscosity meter, but may also be integrated with one or more separation techniques for particles and (polymer) molecules.

Abstract translation: 本发明涉及一种适用于测量流体粘度的装置，该装置包括在所有侧面包围的通道上，以及适于连接到通道用于差压测量的膜。 根据本发明，第一通道位于第一平面中，第二通道位于第二平面中，该第二平面中的第一平面和第二平面相对于彼此基本上平行取向，并且膜位于基本平行于 第一架飞机 这样便于装置充满液体而不会留下气泡的危险。 该装置可以用作独立的粘度计，但也可以与用于颗粒和（聚合物）分子的一种或多种分离技术相结合。

公开(公告)号：WO0137252A3

公开(公告)日：2002-01-24

申请号：PCT/NL0000847

申请日：2000-11-20

Applicant: STICHTING TECH WETENSCHAPP ,  TIJDEMAN HENDRIK ,  EERDEN FREDERICUS JOSEPH MARIE ,  TILLEMA HEDZER GIDO

Inventor： TIJDEMAN HENDRIK ,  VAN DER EERDEN FREDERICUS JOSE ,  TILLEMA HEDZER GIDO

IPC: G10K11/172

CPC classification number: G10K11/172

Abstract: Method for designing a sound-absorbent wall (1) having cavity structures, wherein each cavity structure comprises a primary cavity (2) in a sound-absorbent surface (8) of the wall (1). The method comprises the steps for determination of an absorption spectrum of the sound-absorbent wall (1) as a function of design parameters, which, for each cavity structure, consist of a surface porosity OMEGA of the sound-absorbent surface (8), the primary length of the primary cavity (2) and the primary crosssection of the primary cavity (2), variation of at least one of the design parameters and selection of values of the design parameters where the absorption spectrum meets a desired absorption spectrum. In one embodiment, by means of which the absorption spectrum becomes more broadband, each cavity structure further comprises a secondary cavity (3) and the design parameters further comprise the secondary length of the secondary cavity (3) and the secondary crosssection of the secondary cavity (3).

Abstract translation: 一种用于设计具有空腔结构的吸音墙（1）的方法，其中每个空腔结构包括在所述壁（1）的吸声表面（8）中的主空腔（2）。 该方法包括以下步骤：根据设计参数确定吸音壁（1）的吸收光谱，每个空腔结构由吸声表面（8）的表面孔隙度OMEGA组成， 主空腔（2）的主要长度和主空腔（2）的主要横截面，设计参数中的至少一个的变化和设计参数的值的选择，其中吸收光谱满足期望的吸收光谱。 在一个实施例中，借助于此吸收光谱变得更宽带，每个空腔结构还包括二次空腔（3），并且设计参数还包括次级空腔（3）的次级长度和次级空腔的次级横截面 （3）。

公开(公告)号：WO0160945A2

公开(公告)日：2001-08-23

申请号：PCT/EP0101838

申请日：2001-02-16

Applicant: STICHTING TECH WETENSCHAPP ,  DORENBOS PIETER ,  EIJK CAREL WILHELM EDUARD VAN ,  GUEDEL HANS ULRICH ,  KRAEMER KARL WILHELM ,  LOEF EDGAR VALENTIJN DIEUWER V

Inventor： DORENBOS PIETER ,  VAN EIJK CAREL WILHELM EDUARD ,  GUEDEL HANS-ULRICH ,  KRAEMER KARL WILHELM ,  VAN LOEF EDGAR VALENTIJN DIEUW

IPC: G01T1/20 ,  C01F17/00 ,  C09K11/00 ,  C09K11/08 ,  C09K11/77 ,  C09K11/85 ,  C30B29/12 ,  G01T1/202

CPC classification number: G01T1/2023 ,  C01F17/0056 ,  C01F17/0068 ,  C09K11/7772

Abstract: The invention concerns an inorganic scintillator material of general composition M>1-x x 3

Abstract translation: 本发明涉及通用组合物M> 1-x x xBr 3的无机闪烁体材料，其中：M选自La，Gd，Y中的镧系元素或镧系元素混合物，特别是镧系元素或 由La，Gd组成的组的镧系元素混合物; x是M与铈的摩尔取代度，x不小于0.01mol％且严格小于100mol％。 本发明还涉及用于生长这种单晶闪烁体材料的方法，以及其用于工业和医疗目的的闪烁检测器的组分或在石油工业中的用途。

公开(公告)号：WO0138902A2

公开(公告)日：2001-05-31

申请号：PCT/NL0000861

申请日：2000-11-24

Applicant: UNIV DELFT TECH ,  STICHTING TECH WETENSCHAPP ,  JONGTH RENE DE ,  YAROVOY ALEXANDER ,  SCHUKIN ALEXANDER

Inventor： DE JONGTH RENE ,  YAROVOY ALEXANDER ,  SCHUKIN ALEXANDER

IPC: G01S7/03 ,  G01S13/88 ,  G01V3/12

CPC classification number: G01V3/12

Abstract: Ground penetrating radar system for detecting objects (17) on or below a ground surface (18), comprising at least one transmit antenna (13) having a first foot print (14) at the ground surface, at least one receive antenna (15) having a second foot print (16) at the ground surface, and processing means (11, 12) connected to the at least one transmit antenna (13) and the at least one receive antenna (15), in which the first (14) and second (16) foot print have different dimensions. The transmit antenna (13) and receive antenna (15) are adapted to improve the detection capability of the ground penetrating radar system (10).

Abstract translation: 用于在地表面（18）上或下方检测物体（17）的地面穿透雷达系统，包括在地面具有第一脚印（14）的至少一个发射天线（13），至少一个接收天线（15） 在地面上具有第二脚印（16）以及连接到所述至少一个发射天线（13）和所述至少一个接收天线（15）的处理装置（11,12），其中所述第一（14） 和第二（16）英尺印有不同的尺寸。 发射天线（13）和接收天线（15）适于提高地面穿透雷达系统（10）的检测能力。