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公开(公告)号：ES2784011T3
公开(公告)日：2020-09-21
申请号：ES07008752
申请日：2003-10-16
Applicant: STRECK INC
Inventor： RYAN WAYNE L
Abstract: El uso para estabilizar dentro de un tubo una muestra de células de sangre completa, epiteliales o del líquido cefalorraquídeo extraídas al interior del tubo para su análisis posterior en no más de 2 partes de una mezcla de un anticoagulante y un fijador por 100 partes de la muestra de anticoagulante y el fijador de la muestra, en el que el fijador (26) es seleccionado entre el grupo que consiste en diazolidinil urea e imidazolidinil urea y el anticoagulante comprende ácido etilendiaminatetraacético o sales del mismo.
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公开(公告)号：CA3027953A1
公开(公告)日：2017-12-21
申请号：CA3027953
申请日：2017-06-15
Applicant: STRECK INC
Inventor： TORRES MARIA , HANSON NANCY , LECHNER JOEL , COSSETTE STEPHANIE , SCHEER CATHY , KREIFELS MATTHEW , MORROW STACEY , CONNELLY CHRIS , PORTER LAURA R , FOWLER RANDY
IPC: C12Q1/68
Abstract: Assays and methods for detecting resistance to beta-lactam antibiotics including detection of multiple ß-lactamase family specific gene targets by polymerase chain reaction or microarray. One or more kits including primers and/or probes for identification of ß-lactamase genes selected from the group consisting of one or more of the following:MOX-like, FOX-like, ACC-like, ACT/MIR-like, CMY-2-like, DHA-like, CTX-M-14-like, CTX-M-15-like, VIM-like, NDM-like, IMP-like, KPC-like, and OXA-48-like, OXA-51 -like, OXA-143-like, OXA-58-like, OXA-23-like, OXA-24/40-like, TEM-like, and SHV-like. A kit may also include one or more primers and/or probes for the identification a non-beta lactamase gene family which confers antibiotic resistance, such as the MCR-1 gene.
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公开(公告)号：CA2716337C
公开(公告)日：2017-11-14
申请号：CA2716337
申请日：2009-02-19
Applicant: STRECK INC
Inventor： TERMAAT JOEL R , VILJOEN HENDRIK J , WHITNEY SCOTT E
Abstract: A thermocycler apparatus and method for rapidly performing the PCR process employs at least two thermoelectric modules which are in substantial spatial opposition with an interior space present between opposing modules. One or multiple sample vessels are placed in between the modules such that the vessels are subjected to temperature cycling by the modules. The sample vessels have a minimal internal dimension that is substantially perpendicular to the modules that facilitates rapid temperature cycling. In embodiments of the invention the sample vessels may be deformable between a) a shape having a wide mouth to facilitate filling and removing of sample fluids from the vessel, and b) a shape which is thinner for conforming to the sample cavity or interior space between the thermoelectric modules of the thermocycler for more rapid heat transfer.
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公开(公告)号：DE202013012535U1
公开(公告)日：2017-08-28
申请号：DE202013012535
申请日：2013-02-13
Applicant: STRECK INC
IPC: C12N15/10
Abstract: Probensammelbehälter, enthaltend: eine Blutprobe oder Blutplasmaprobe; mindestens eine zirkulierende, zellfreie, erste Nukleinsäure, die DNA oder RNA ist; eine Schutzmittelzusammensetzung, welche ein Konservierungsmittel, ausgewählt aus Diazolidinylharnstoff, Imidazolidinylharnstoff, Dimethoylol-5,5-dimethylhydantoin, Dimethylolharnstoff, 2-Brom-2.-nitropropan-1,3-diol, Oxazolidinen, Natriumhydroxymethylglycinat, 5-Hydroxymethoxymethyl-1-1aza-3,7-dioxabicyclo[3.3.0]octan, 5-Hydroxymethyl-1-1aza-3,7-dioxabicyclo[3.3.0]octan, 5-Hydroxypoly[methylenoxy]-methyl-1-1aza-3,7dioxabicyclo[3.3.0]octan, quaternärem Adamantin oder einer Kombination davon; ein Anticoagulans und ein Quentsch-Mittel enthält; ein Reaktionsprodukt, das durch die Probe und die Schutzmittelzusammensetzung gebildet wird, welches: (i) inert für die Nukleinsäure der biologischen Probe; und (ii) frei von Aldehyd ist; sodass die Nukleinsäuren darin dann für eine Polymerase-Kettenreaktion und DNA-Sequenzierung ohne Einfrieren der Probe für mindestens 7 Tage geeignet sind und die DNA frei von Aldehyd-induzierter (i) Nukleinsäure-Protein-Vernetzung, (ii) intramolekularen und/oder intermolekularen Nukleinsäure-Nukleinsäure-Vernetzungen oder sowohl (i) als auch (ii) ist, durch Quentschen von sämtlichem freien Formaldehyd, das vorhanden sein kann, mit dem Quentsch-Mittel aus der Schutzmittelzusammensetzung.
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公开(公告)号：DK2228453T3
公开(公告)日：2017-02-27
申请号：DK10000518
申请日：2010-01-20
Applicant: STRECK INC
Inventor： FERNANDO M ROHAN , CHAO-WEI CHEN KATE
IPC: C12Q1/68
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Patent Agency Ranking
公开(公告)号：CA2835654A1
公开(公告)日：2012-12-06
申请号：CA2835654
申请日：2012-05-31
Applicant: STRECK INC
Inventor： TERMAAT JOEL R , WHITNEY SCOTT E , VILJOEN HENDRIK J , KREIFELS MATTHEW R
Abstract: A thermocycling device (10) and method of operating in which at least one first temperature sensor (1060) monitors a first temperature condition within the sample holder (64) and is adapted to provide a first electrical signal corresponding with the first temperature condition. In addition, at least one second temperature sensor (87) monitors a second temperature condition of a component external of the sample holder and is adapted to provide a second signal corresponding with the second temperature condition. At least one control device is adapted to interface with a power supply (1010) to control the delivery of power to a first thermal cycling element (60) and a second thermal cycling element (62), (both of which may sandwich a sample holder) and optionally an air mover (54); adapted to be in signaling communication with the first temperature sensor and the second temperature sensor; is configured for analysis of signals from the first temperature sensor and the second temperature sensor and; is configured such that, based upon such analysis, the at least one control device alters the power that is delivered to one or more of the first thermal cycling element and second thermal cycling element, and/or the air mover. The device Is controllably operated to account for thermal inertia effects.
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公开(公告)号：CA2780536A1
公开(公告)日：2011-05-12
申请号：CA2780536
申请日：2010-11-08
Applicant: STRECK INC
Inventor： RYAN WAYNE L , FERNANDO M ROHAN
Abstract: A method for preserving and processing nucleic acids located within a blood sample is disclosed, wherein a blood sample containing nucleic acids is treated to reduce both blood cell lysis and nuclease activity within the blood sample. The treatment of the sample aids in increasing the integrity and amount of cellular nucleic acids that can be identified and tested while avoiding contamination of the isolated nucleic acids with cell -free nucleic acids. The preferred compositions for preserving and processing contain diazolidinyl urea (DU), EDTA, aurintricarboxylic acid (ATA), glyceraldehyde and sodium floride.
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公开(公告)号：CA2538968A1
公开(公告)日：2006-09-10
申请号：CA2538968
申请日：2006-03-08
Applicant: STRECK INC
Inventor： HUNSLEY BRADFORD A , RYAN WAYNE L
Abstract: Improvements in blood collection and testing. In one aspect, an improved method of manufacturing a blood collection tube, particularly illustrated for use in sedimentation rate testing, including providing an elongated glass tube with an open first end for receiving a venipuncture blood sample of at least 1 ml, formed with a closed end opposite the first end; an d applying to a substantial portion of the receptacle a containment barrier. The improvements also perta in to resulting blood collection tubes, additives for blood collection tubes that permit reliable sedimentation test data after 8 hours from the blood draw, and methods of administering health care using the aforenoted tubes, additives or both.
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公开(公告)号：CA3124698A1
公开(公告)日：2020-07-02
申请号：CA3124698
申请日：2019-12-27
Applicant: STRECK INC
Inventor： SOBANSKY MATTHEW
Abstract: Provided herein are methods of preparing a protein sample for proteomic analysis. In exemplary embodiments, the method comprises (a) contacting a blood sample comprising proteins with a protective agent comprising an anticoagulant (AC) and an aldehyde releaser (AR), to obtain a mixture, optionally, wherein the blood sample is added to a blood collection tube (BCT) comprising the protective agent, and (b) isolating a fraction comprising proteins or a source of proteins from the mixture to yield a protein sample or a source of a protein sample, wherein steps of the method are carried out in the absence of exogenous proteolytic enzyme inhibitors, wherein the protein sample is suitable for proteomic analysis. Preferably, the protective agent consists of essentially (i) about 300 g/l to about 700 g/l imidazolidinyl urea; (ii) about 20 g/l to about 60 g/l glycine; and (iii) about 60 g/l to about 100 g/l EDTA; and the the protein sample is analysed via mass spectrometry-based proteomic methods.
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公开(公告)号：DK2626438T3
公开(公告)日：2020-06-29
申请号：DK13166264
申请日：2010-01-20
Applicant: STRECK INC
Inventor： FERNANDO ROHAN , CHAO-WEI CHEN KATE
IPC: C12Q1/6806
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