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公开(公告)号：KR1020100104343A
公开(公告)日：2010-09-29
申请号：KR1020090022704
申请日：2009-03-17
Applicant: (주)아모레퍼시픽
IPC: A61K31/353 , A61K8/49 , A61P17/10 , A61Q19/08
Abstract: PURPOSE: A composition for relieving skin irritation is provided to suppress expression of inflammatory intermediate factor. CONSTITUTION: A composition for relieving skin irritation contains a compound of chemical formula 1, isomer or pharmaceutically acceptable salt thereof as an active ingredient. The composition is used for relieving skin irritation including skin dryness, inflammation, erythema, or itchness. The skin irritation by an external skin ingredient is skin irritation by retinoid or surfactant. The retinoid is retinol, retinal or retinoic acid. An external use skin formulation for treating dermatitis contains the composition.
Abstract translation: 目的：提供缓解皮肤刺激的组合物，以抑制炎性中间因子的表达。 构成：用于缓解皮肤刺激的组合物含有化学式1化合物，其异构体或其药学上可接受的盐作为活性成分。 该组合物用于缓解皮肤刺激，包括皮肤干燥，炎症，红斑或瘙痒。 外用皮肤成分引起的皮肤刺激是类视黄醇或表面活性剂引起的皮肤刺激。 类视色素是视黄醇，视黄醛或视黄酸。 用于治疗皮炎的外用皮肤制剂含有该组合物。
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12.发明授权바닐로이드 수용체 길항제로 작용하는 신규 화합물, 이의 이성질체 또는 이의 약제학적으로 허용 가능한 염 및 이를 포함하는 약학 조성물 有权其新颖的化合物异构体或其药学上可接受的盐作为包含它们的泛脲受体拮抗剂和药物组合物
公开(公告)号：KR101645537B1
公开(公告)日：2016-08-05
申请号：KR1020090108632
申请日：2009-11-11
Applicant: (주)아모레퍼시픽
IPC: C07D323/04 , A61K31/357
Abstract: 본발명은바닐로이드수용체(Vanilloid Receptor 1; VR1; TRPV1) 길항제로작용하는신규화합물, 이의이성질체또는이의약제학적으로허용가능한염; 및이를포함하는약학조성물에관한것이다. 본발명은통증, 편두통(migraine), 관절통(arthralgia), 신경통(neuralgia), 신경장해(neuropathies), 신경손상(nerve injury), 피부질환(skin disorder), 비뇨방광과민증(urinary bladder hypersensitiveness), 과민성대장증후군(irritable bowel syndrome), 절박배변(fecal urgency), 호흡기질환(respiratory disorder), 위-십이지장궤양(stomach-duodenal ulcer), 염증질병(inflammatory diseases), 귓병(ear disease), 심장병(heart disease) 등과같은질병의예방또는치료용약학조성물을제공한다.
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公开(公告)号：KR1020120027436A
公开(公告)日：2012-03-21
申请号：KR1020117031696
申请日：2010-06-18
Applicant: (주)아모레퍼시픽
CPC classification number: A61Q19/005 , A61K8/97 , A61K36/49
Abstract: PURPOSE: A cosmetic composition containing nutshell extract is provided to suppress proteinase-activated receptor-2(PAR-2) and to relieve itching. CONSTITUTION: A cosmetic composition for relieving or suppressing itching contains nutshell extract as an active ingredient. The composition prevents or relieves itching caused by inflammatory dermatitis, atopic dermatitis, miliaria, frostbite, contact dermatitis, seborrheic dermatitis, or pruritus. A cosmetic composition improving skin barrier function contains the nutshell extract as an active ingredient. The extract is prepared using water, low alcohol of C1-4, 1,3-butylene glycol, or mixture thereof.
Abstract translation: 目的：提供含有坚果壳提取物的化妆品组合物，以抑制蛋白酶激活的受体-2（PAR-2）并缓解瘙痒。 构成：用于缓解或抑制瘙痒的化妆品组合物含有坚果壳提取物作为活性成分。 该组合物预防或缓解由炎症性皮炎，特应性皮炎，睫毛膏，冻伤，接触性皮炎，脂溢性皮炎或瘙痒引起的瘙痒。 改善皮肤屏障功能的化妆品组合物含有坚果壳提取物作为活性成分。 提取物是使用C 1-4，1,3-丁二醇或其混合物的水，低级醇制备的。
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14.发明公开바닐로이드 수용체 길항제로 작용하는 신규 화합물, 이의 이성질체 또는 이의 약제학적으로 허용 가능한 염 및 이를 포함하는 약학 조성물 有权新型化合物，异构体或其药学上可接受的盐作为VANULLOID受体拮抗剂和含有其的药物组合物
公开(公告)号：KR1020100053470A
公开(公告)日：2010-05-20
申请号：KR1020090108632
申请日：2009-11-11
Applicant: (주)아모레퍼시픽
IPC: C07D323/04 , A61K31/357
Abstract: PURPOSE: A novel compound which functions as a vanilloid receptor 1(VR1) antagonist is provided to prevent or treat disease related to hair growth, rhinitis, and pancreatitis. CONSTITUTION: A vanilloid receptor antagonist compound is denoted by chemical formula I. A pharmaceutical composition contains the compound, isomer, or pharmaceutically acceptable salt thereof. The composition is used for preventing or treating arthritis disease, neuropathy, HIV related neuropathy, nerve injury, neurodegeneration, cerebral apoplexy, urinary incontinence, cough, neuropathy/allergy/inflammation skin disease, atopic dermatitis, psoriasis, pruritus, the prurigo, acouesthesia, aliasing, bregma anaphylaxis, effluvium, or alopecia.
Abstract translation: 目的：提供作为香草素受体1（VR1）拮抗剂起作用的新型化合物，以预防或治疗与毛发生长，鼻炎和胰腺炎有关的疾病。 构成：香草素受体拮抗剂化合物由化学式I表示。药物组合物含有化合物，异构体或其药学上可接受的盐。 该组合物用于预防或治疗关节炎疾病，神经病，HIV相关神经病，神经损伤，神经变性，脑中风，尿失禁，咳嗽，神经病变/过敏/炎症皮肤病，特应性皮炎，牛皮癣，瘙痒，瘙痒症，麻醉， 混叠，原发性过敏性反应，流出或脱发。
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Patent Agency Ranking15.发明授权바닐로이드 수용체 길항제로 작용하는 신규 화합물, 이의 이성질체 또는 이의 약제학적으로 허용 가능한 염, 및 이를 포함하는 약학 조성물 有权其新型化合物异构体或其药学上可接受的盐作为VANILLOID受体拮抗剂和含有该抗体的药物组合物
公开(公告)号：KR101621444B1
公开(公告)日：2016-05-19
申请号：KR1020117002414
申请日：2009-07-02
Applicant: (주)아모레퍼시픽
Inventor： 우병영 , 김선영 , 김연준 , 신송석 , 김진관 , 이기화 , 김동현 , 임경민 , 모주현 , 정연수 , 최진규 , 고현주 , 이정오 , 김혁 , 윤정훈 , 리,푸난 , 김지숙 , 서영거
IPC: C07D263/36 , C07D277/22 , A61K31/421 , A61P25/00
CPC classification number: C07D263/42 , C07D263/34 , C07D263/38 , C07D263/48 , C07D277/42 , C07D277/56 , C07D307/52 , C07D307/68 , C07D333/38 , C07D413/04 , C07D413/12
Abstract: 본발명은바닐로이드수용체(Vanilloid Receptor 1; VR1; TRPV1) 길항제로작용하는신규화합물, 이의이성질체또는이의약제학적으로허용가능한염; 및이를포함하는약학조성물에관한것이다. 본발명은통증, 편두통(migraine), 관절통(arthralgia), 신경통(neuralgia), 신경장해(neuropathies), 신경손상(nerve injury), 피부질환(skin disorder), 비뇨방광과민증(urinary bladder hypersensitiveness), 과민성대장증후군(irritable bowel syndrome), 절박배변(fecal urgency), 호흡기질환(respiratory disorder), 피부, 눈또는점막자극(irritation of skin, eye or mucous membrane), 위-십이지장궤양(stomach-duodenal ulcer), 염증질병(inflammatory diseases), 귓병(ear disease), 심장병(heartdisease) 등과같은질병의예방또는치료용약학조성물을제공한다.
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公开(公告)号：KR1020170048161A
公开(公告)日：2017-05-08
申请号：KR1020160130607
申请日：2016-10-10
Applicant: (주)아모레퍼시픽
Abstract: 본명세서는 HLB (Hydrophile-Lipophile Balance)가 1~9인올레산에스테르계유화제를포함하는분사형화장료조성물에관하여기술한다. 상기조성물은분사각이넓고분사되는입자의크기가미세하며균일할수 있다.
Abstract translation: 本说明书描述了包含亲水亲油平衡值（HLB）为1至9的油酸酯基润滑剂的喷雾型化妆品组合物。 该组合物具有宽广的喷射角度并且喷射颗粒的尺寸精细且均匀。
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公开(公告)号：KR101115120B1
公开(公告)日：2012-02-24
申请号：KR1020090054598
申请日：2009-06-18
Applicant: (주)아모레퍼시픽
Abstract: 본 발명은 율피 추출물을 유효 성분으로 함유하는 모발용 화장료 조성물에 관한 것이다. 본 발명에 따른 모발용 화장료 조성물은 율피 추출물을 통해 민감성, 자극성 및/또는 반응성 두피를 안정화시키고, 두피의 가려움, 열감 및/또는 염증을 효과적으로 개선시켜, 두피를 건강하게 유지할 수 있다.
율피, 모발용 화장료 조성물-
18.发明公开바닐로이드 수용체 길항제로 작용하는 신규 화합물, 이의 이성질체 또는 이의 약제학적으로 허용 가능한 염, 및 이를 포함하는 약학 조성물 有权新型化合物，异构体或其药学上可接受的盐作为VANILLOID受体拮抗剂和含有其的药物组合物
公开(公告)号：KR1020110029160A
公开(公告)日：2011-03-22
申请号：KR1020117002414
申请日：2009-07-02
Applicant: (주)아모레퍼시픽
Inventor： 우병영 , 김선영 , 김연준 , 신송석 , 김진관 , 이기화 , 김동현 , 임경민 , 모주현 , 정연수 , 최진규 , 고현주 , 이정오 , 김혁 , 윤정훈 , 리,푸난 , 김지숙 , 서영거
IPC: C07D263/36 , C07D277/22 , A61K31/421 , A61P25/00
CPC classification number: C07D263/42 , C07D263/34 , C07D263/38 , C07D263/48 , C07D277/42 , C07D277/56 , C07D307/52 , C07D307/68 , C07D333/38 , C07D413/04 , C07D413/12
Abstract: PURPOSE: A compound is provided to treat heart diseases, pain, and hair growth-associated diseases. CONSTITUTION: A pharmaceutical composition for preventing and treating pharmacological stimulation and/or abnormal expression of vaniloid receptor 1(VR1) contains a compound of chemical formula I, II, III, or IV, isomer thereof, or pharmaceutically acceptable salt and pharmaceutically acceptable carrier. The pharmaceutical composition is applied to rat, mouse, livestock, and human. The pharmaceutical composition is used by rectal, intravenous, intramuscular, or subcutaneous administration.
Abstract translation: 目的：提供化合物治疗心脏病，疼痛和毛发生长相关疾病。 构成：用于预防和治疗紫杉醇受体1（VR1）的药理学刺激和/或异常表达的药物组合物含有化学式I，II，III或IV的化合物，其异构体或其药学上可接受的盐和药学上可接受的载体。 药物组合物适用于大鼠，小鼠，家畜和人类。 药物组合物通过直肠，静脉内，肌肉内或皮下给药使用。
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公开(公告)号：KR1020100136308A
公开(公告)日：2010-12-28
申请号：KR1020090054598
申请日：2009-06-18
Applicant: (주)아모레퍼시픽
CPC classification number: A61K8/97 , A61K36/15 , A61K36/16 , A61K36/49 , A61K36/82 , A61Q5/02 , A61Q5/12 , A61Q7/00 , Y10S514/881 , Y10S514/886
Abstract: PURPOSE: A cosmetic composition containing Chestnut Inner Bark extract for hair care is provided to stabilize sensitive, irritative, and/or reactive scalp. CONSTITUTION: A cosmetic composition for hair care contains Chestnut Inner Bark extract as an active ingredient. The composition further contains green tea extract, pine needle extract, or ginkgo leaf extract as active ingredient. The active ingredient is contained in 0.01-10.0 weight% based on total weight. The composition is manufactured in the form of hair tonic, hair essence, hair serum, hair treatment, hair conditioner, hair shampoo, or hair lotion.
Abstract translation: 目的：提供含有用于头发护理的栗子内皮提取物的化妆品组合物以稳定敏感，刺激性和/或反应性头皮。 构成：用于护发的化妆品组合物含有栗子内皮提取物作为活性成分。 该组合物还含有绿茶提取物，松针提取物或银杏叶提取物作为活性成分。 活性成分以总重量计为0.01-10.0重量％。 该组合物以头发补品，头发精华，头发血清，头发处理，护发素，洗发剂或洗发剂的形式制造。
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