Abstract:
PURPOSE: An asymmetric processing apparatus and method and a material processed using the same are provided to improve room-temperature formability of extruded-rolled materials by arranging a slip system to easily induce shear transformation at room temperature. CONSTITUTION: An asymmetric processing method comprises a step of pushing out a material through dies(230) with an extrusion hole having an asymmetric shape in the planar direction of the material to induce internal shear transformation along the thickness of the material and extrude the material(250), thereby obtaining an extruded material(260) and a step of pushing the extruded material between first and second rolls(101,102) with difference diameters to induce shear transformation on the extruded material and roll the extruded material, thereby obtaining a rolled material. The extrusion hole of the dies includes a tapered portion(234) varying in width in the extrusion direction of the extruded material.
Abstract:
PURPOSE: An asymmetrical rolling device and method and a rolled material sheet produced using the same are provided to prevent slip of a work piece and reduce bending of the work piece by applying asymmetrical shear stress, caused by a different between the diameters of rolls on both sides, while the rolls are operated at the same rotational linear velocity. CONSTITUTION: In an asymmetrical rolling method, a work piece(104) is rolled through first and second rolls(101,102) with first and second sides(104a,104b) contacting the first and second rolls. The second roll has a diameter greater than that of the first roll and a rotational angular speed different from that of the first roll. The work piece is rolled between third and fourth rolls(201,202) with the first and second sides contacting the third and fourth rolls. The fourth roll has a diameter greater than that of the third roll and a rotational angular speed different from that of the third roll. Therefore, different shear stresses are applied to the first and second sides of the work piece.
Abstract:
PURPOSE: A peptide which binds to cyclodextrin and a method for preparing the same are provided to form a complex by being conjugated with a specific protein. CONSTITUTION: A peptide which binds to cyclodextrin has LPVRPWT(CD-01), LPLTPLP(CD-02), LPPQTLI(CD-03), or NQDVPLF(CD-04). The peptide introduces a functional group or ligand to cyclodextrin by being conjugated to cyclodextrin. A method for detecting the peptide comprises: a step of searching a phage-peptide library; a step of adding the phage-peptide library to cyclodextrin polymer beads and biopanning; and a step of detecting a base sequence of a peptide with high frequency.
Abstract:
비대칭 압출방법, 이를 이용하여 압출된 압출재, 비대칭 압출용 다이스 및 비대칭 압출장치가 제공된다. 비대칭 압출방법에 의하면, 피압출재의 압출 방향을 기준으로 비대칭적 형상의 압출 구멍을 갖는 다이스를 통해서 상기 피압출재를 밀어내어 상기 피압출재에 전단변형을 유도하면서 상기 피압출재를 압출하여 판재 형상의 압출재를 형성한다.
Abstract:
본 발명은 기능성 작용기를 물질의 표면에 도입하는 방법에 관한 것이다. 본 발명에 따르면, 기능성 작용기를 갖는 화합물을 지질과 혼합하여 물질의 표면에 도입하는 방법이 제공된다. 본 발명에 따른 방법은 예를 들면, 기능성 작용기를 갖는 화합물을 지질과 혼합하여 리포솜을 형성하는 단계; 및 상기 리포솜을 상기 물질의 표면에 도입하는 단계를 포함한다. 본 발명에 따라 기능성 작용기를 물질의 표면에 도입하는 방법은 종래의 화학적인 표면 처리 방법에 비해 공정이 간편하고 시간이 단축될 뿐만 아니라 물질의 표면에 수용체를 고정함에 있어서 효율 및 재현성이 높은 효과가 있다. 또한 여러 시약을 사용할 필요가 없고 간단하여 화학 비전공자 들도 쉽게 활용할 수 있다. 기능성 작용기, 지질, 표면 화학, 수용체
Abstract:
PURPOSE: A detecting method of various analytes(A,B,C) for a biosensor is provided to simplify the manufacturing process of a biosensor chip, and to improve the profitability of the biosensor. CONSTITUTION: A detecting method of various analytes for a biosensor comprises the following steps: dividing a sample containing the various analytes into multiple fractions; and inserting each fraction to a biosensor chip including plural receptors for the various analytes and successively detecting each analyte. The dividing process is performed by the chromatography or the electrophoresis and isoelectric focusing.
Abstract:
본 고안은 수정결정 미소저울(QCM) 바이오센서 장치에 관한 것으로서, 더욱 상세하게는 간편한 방법으로 수용체 분자를 센서 칩 표면에 고정시킬 수 있고 기상 또는 액상의 시험 대상물을 용이하게 센서와 접촉시킬 수 있으면서 안정된 신호를 얻을 수 있는, 수정결정 미소저울(QCM) 바이오센서 장치에 관한 것이다. 본 고안에 의하면, QCM을 사용한 바이오센서 칩이 회로에 연결된 상태로 우물형 셀 (batch type cell)과 흐름형 셀 (flow type cell)의 상호 교체가 가능하여, 용이하게 정지상태의 시험 대상물과 흐름상태의 시험 대상물 모두의 측정을 가능하게 한다. 또한 본 고안에 의하면, 온도를 비롯한 주위 환경에 민감한 오실레이터 회로와 바이오센서 칩을 수용한 셀을 각각 독립된 체임버(chamber)에 격리시킨 구조를 채택하여 신호의 안정성을 높이게 된다. 수정결정 미소저울(QCM), 흐름형, 우물형, 바이오센서
Abstract:
A sensor for a QCM(Quarts Crystal Microbalance) system is provided to easily fix a receptor molecule on a surface by easily contacting a test object in the liquid phase or vapor phase with the sensor. A sensor for a QCM(Quarts Crystal Microbalance) system includes a sensor structure(100), a housing(200), and a pair of connecting wires(300). The sensor structure is made of several layers laminating on a circular quarts crystal substrate. The sensor housing has a receiving space for the sensor structure and safely receives the sensor structure in the receiving space. A metal thin film layer is formed on each plane of the sensor structure. The connecting wires are electrically connected to the metal thin film layer and are elongated outside the sensor housing. In a self assembly monomolecular layer of the sensor structure, anyone type of groups of a carboxyl group or an amino group is mixed with a hydroxy group at a side being far from the metal thin film layer.