公开(公告)号：KR101213445B1

公开(公告)日：2012-12-18

申请号：KR1020110003653

申请日：2011-01-13

Applicant: 강원대학교산학협력단

Inventor： 한장희 ,  김민서 ,  조혜정

IPC: A61K38/07 ,  A61K38/06 ,  A61P35/00 ,  A61P29/00

Abstract: 본발명은막횡단단백질의일종인 CD166(ALCAM)에서유래한펩타이드단편, 즉서열번호 1 내지 3의아미노산서열로구성된펩타이드로이루어진군으로부터선택된펩타이드를유효성분으로포함하는염증질환예방또는치료용약학조성물; 및암전이억제용약학조성물을제공한다.

公开(公告)号：KR1020120082262A

公开(公告)日：2012-07-23

申请号：KR1020110003653

申请日：2011-01-13

Applicant: 강원대학교산학협력단

Inventor： 한장희 ,  김민서 ,  조혜정

IPC: A61K38/07 ,  A61K38/06 ,  A61P35/00 ,  A61P29/00

CPC classification number: A61K38/06 ,  A61K38/07 ,  Y10S514/886

Abstract: PURPOSE: A pharmaceutical composition containing peptide fragments derived from CD166(ALCAM) is provided to suppress leukemia extravasation or treating inflammatory diseases. CONSTITUTION: A pharmaceutical composition for preventing or treating inflammatory diseases contains peptides having amino acids of sequence numbers 1-3 as an active ingredient and pharmaceutically acceptable carrier. The inflammatory diseases are caused by hypersensitive reaction. A pharmaceutical composition for suppressing cancer metastasis contains the peptides as an active ingredient and pharmaceutically acceptable carrier.

Abstract translation: 目的：提供含有衍生自CD166（ALCAM）的肽片段的药物组合物，以抑制白血病外渗或治疗炎性疾病。 构成：用于预防或治疗炎性疾病的药物组合物含有具有序列号1-3的氨基酸作为活性成分的肽和药学上可接受的载体。 炎性疾病是由过敏反应引起的。 用于抑制癌症转移的药物组合物含有肽作为活性成分和药学上可接受的载体。

公开(公告)号：KR1020120082259A

公开(公告)日：2012-07-23

申请号：KR1020110003648

申请日：2011-01-13

Applicant: 강원대학교산학협력단

Inventor： 한장희 ,  이한수 ,  정두일 ,  최종선 ,  김민서

IPC: A61K38/07 ,  A61K38/06 ,  A61P35/00

CPC classification number: A61K38/06 ,  A61K38/07 ,  Y10S514/886

Abstract: PURPOSE: A pharmaceutical composition containing peptide fragments derived from CD47 is provided to prevent or treat inflammatory diseases and to suppress cancer cell proliferation and/or metastasis. CONSTITUTION: A pharmaceutical composition for preventing or treating inflammatory diseases contains peptides having amino acids of sequence numbers 1-3 as an active ingredient and pharmaceutically acceptable carrier. A pharmaceutical composition for suppressing cancer growth or metastasis contains the peptides as an active ingredient. The peptide has an amino acid sequence of sequence number 3.

Abstract translation: 目的：提供含有衍生自CD47的肽片段的药物组合物，用于预防或治疗炎性疾病并抑制癌细胞增殖和/或转移。 构成：用于预防或治疗炎性疾病的药物组合物含有具有序列号1-3的氨基酸作为活性成分的肽和药学上可接受的载体。 用于抑制癌症生长或转移的药物组合物含有肽作为活性成分。 该肽具有序列号3的氨基酸序列。