Abstract:
PURPOSE: A pharmaceutical composition containing peptide fragments derived from CD166(ALCAM) is provided to suppress leukemia extravasation or treating inflammatory diseases. CONSTITUTION: A pharmaceutical composition for preventing or treating inflammatory diseases contains peptides having amino acids of sequence numbers 1-3 as an active ingredient and pharmaceutically acceptable carrier. The inflammatory diseases are caused by hypersensitive reaction. A pharmaceutical composition for suppressing cancer metastasis contains the peptides as an active ingredient and pharmaceutically acceptable carrier.
Abstract:
PURPOSE: A pharmaceutical composition containing allergin-1-derived peptide fragments is provided to suppress leukocyte extravasation and mast cell degranulation and to prevent or treat inflammatory diseases and allergy. CONSTITUTION: A pharmaceutical composition for preventing or treating inflammatory diseases contains peptides having an amino acid of sequence number 1 or peptides having an amino acid of sequence number 2 as an active ingredient and pharmaceutically acceptable carrier.
Abstract:
본 발명은 막횡단 단백질의 일종인 allergin-1에서 유래한 펩타이드 단편, 즉 서열번호 1의 아미노산 서열로 구성된 펩타이드 또는 서열번호 2의 아미노산 서열로 구성된 펩타이드를 유효성분으로 포함하는 염증 질환 또는 알레르기의 예방 또는 치료용 약학 조성물을 제공한다.