公开(公告)号：KR101133243B1

公开(公告)日：2012-04-06

申请号：KR1020090103723

申请日：2009-10-29

Applicant: 국립암센터

Inventor： 이연수 ,  고성호 ,  홍성혜 ,  김인후 ,  정진숙

IPC: C12Q1/68 ,  C12N15/11 ,  G01N33/574 ,  A61K39/395

CPC classification number: G01N33/57415 ,  C12N15/113 ,  C12N2310/11 ,  C12N2310/14 ,  C12N2310/16 ,  C12N2310/531 ,  C12Q1/6886 ,  C12Q2600/136 ,  C12Q2600/156 ,  G01N33/57407 ,  G01N33/57419 ,  G01N33/57423 ,  G01N33/57426 ,  G01N33/5743

Abstract: Disclosed are a cancer marker-detecting composition comprising an agent for measuring an mRNA or protein expression level of eIF3m, a cancer diagnosis kit comprising the same, a method for detecting an eIF3m polynucleotide or protein by treating a biological specimen with the agent to detect a substance binding specifically to the agent and quantitatively comparing the substance between a subject and a normal control, and a method for the treatment and prevention of cancer comprising an agent for down-regulating the expression of an eIF3m polynucleotide or protein.