엉겅퀴 추출물 또는 그로부터 분리한 루테오린5―O―β―D―글루코피라노시드의 화합물을 함유한 염증성 질환 예방 또는 치료용 약학조성물 및 건강기능식품
    14.
    发明公开
    엉겅퀴 추출물 또는 그로부터 분리한 루테오린5―O―β―D―글루코피라노시드의 화합물을 함유한 염증성 질환 예방 또는 치료용 약학조성물 및 건강기능식품 无效
    包含食品和健康食品的组合物5-O-β-D-吡喃葡萄糖苷或用于预防或治疗炎症疾病的环孢菌素的提取物

    公开(公告)号:KR1020130087928A

    公开(公告)日:2013-08-07

    申请号:KR1020120009195

    申请日:2012-01-30

    Inventor: 최재수 정현아

    Abstract: PURPOSE: A pharmaceutical composition and a health food for preventing or treating inflammatory diseases are provided to suppress lipopolysaccharide-induced NO generation in RAW 264.7 macrophage and beef feet inflammation in a carrageenan-induced mouse, thereby strongly preventing inflammatory diseases and having stability as a natural medicinal material. CONSTITUTION: A pharmaceutical composition for preventing or treating inflammatory diseases contains a luteolin-5-O-beta-D-glucopyranoside compound as an active ingredient. The compound is derived from Cirsium maackii MAX. The pharmaceutical composition contains a crude extract or a non-solvent soluble extract of Cirsium maackii MAX as an active ingredient. The extract contains the luteolin-5-O-beta-D-glucopyranoside compound of chemical formula 1. A health food for preventing or treating inflammatory diseases contains the composition.

    Abstract translation: 目的:提供用于预防或治疗炎性疾病的药物组合物和保健食品,以抑制角叉菜胶诱导的小鼠中RAW 264.7巨噬细胞和牛脚炎症中的脂多糖诱导的NO产生,从而强烈地预防炎性疾病并且具有作为天然的稳定性 药材。 构成:用于预防或治疗炎性疾病的药物组合物含有作为活性成分的木犀草素-5-O-β-D-吡喃葡萄糖苷化合物。 该化合物衍生自Cirsium maackii MAX。 该药物组合物含有作为活性成分的粗提取物或不溶于水溶性的粟米镰刀菌提取物。 提取物含有化学式1的木犀草素-5-O-β-D-吡喃葡萄糖苷化合物。用于预防或治疗炎性疾病的保健食品含有该组合物。

    엉겅퀴 추출물 또는 그로부터 분리한 루테오린5―O―β―D―글루코피라노시드의 화합물을 함유한 염증성 질환 예방 또는 치료용 약학조성물 및 건강기능식품
    20.
    发明公开
    엉겅퀴 추출물 또는 그로부터 분리한 루테오린5―O―β―D―글루코피라노시드의 화합물을 함유한 염증성 질환 예방 또는 치료용 약학조성물 및 건강기능식품 无效
    包含食品和健康食品的组合物5-O-B-D-GLUCOPYRANOSIDE或用于预防或治疗炎症疾病的环孢菌素的提取物

    公开(公告)号:KR1020140016217A

    公开(公告)日:2014-02-07

    申请号:KR1020130161917

    申请日:2013-12-23

    Inventor: 최재수 정현아

    Abstract: The present invention relates to a pharmaceutical composition and a health functional food containing raw extract and non polar solvent-soluble extract of Cirsium maackii, or a compound of luteolin 5-O-β-D-glucopyranoside for preventing or treating inflammatory diseases. An active ingredient has an anti-inflammatory activity in lipopolysaccharides-induced nitrogen oxide generation of RAW 264.7 macrophage and right leg edema in carrageenan-induced mice. Thus, the Cirsium maackii extract has a strong preventive activity against the inflammatory diseases and secures the safety as a natural medicinal herb, thereby being able to be useful as the pharmaceutical composition and health functional food for preventing or treating the inflammatory diseases.

    Abstract translation: 本发明涉及药用组合物和含有生姜提取物的非极性溶剂可溶性提取物,或用于预防或治疗炎性疾病的木犀草素5-O-β-D-吡喃葡萄糖苷的化合物的保健功能食品。 活性成分在角叉菜胶诱导的小鼠中脂多糖诱导的RAW 264.7巨噬细胞和右腿水肿的氮氧化物产生中具有抗炎活性。 因此,马鞭草提取物对炎性疾病具有很强的预防作用,确保了作为天然药草的安全性,从而能够用作预防或治疗炎性疾病的药物组合物和保健功能食品。

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