公开(公告)号：KR101933622B1

公开(公告)日：2018-12-28

申请号：KR1020120112094

申请日：2012-10-09

Applicant: 삼성전자주식회사

Inventor： 강현주 ,  용예령 ,  이묘용

IPC: G01N33/52 ,  G01N33/58

Abstract: 시료 중 소포를 모니터링하기 위한 조성물, 키트 및 이를 이용한 시료 중 소포를 모니터링하는 방법에 의하면, 프로세스 모니터링이 가능하고, 내부 대조군으로 이용가능하며, 시료의 품질 관리에 이용가능하고, 소포의 위치를 추적할 수 있다.

公开(公告)号：KR1020150043937A

公开(公告)日：2015-04-23

申请号：KR1020130122962

申请日：2013-10-15

Applicant: 삼성전자주식회사

Inventor： 용예령 ,  강현주 ,  김가희 ,  박경희 ,  박종면

IPC: G01N33/574 ,  G01N33/53 ,  C12Q1/68 ,  C12N15/11 ,  G01N33/58

CPC classification number: C07K16/303 ,  C07K16/2896 ,  G01N33/57438 ,  C12Q1/6834 ,  C12Q1/6886 ,  C12Q2563/161 ,  C12Q2600/178 ,  G01N33/5308 ,  G01N33/586 ,  G01N2033/57461

Abstract: TMED2, CD43, 또는그 조합에특이적으로결합하는물질을포함하는개체의간암진단용조성물, 개체의간암진단하는방법및 개체의간암진단에필요한정보를얻는방법을제공한다.

Abstract translation: 本发明提供一种用于诊断对象的肝癌的组合物，其包含与TMED2，CD43或其组合特异性结合的材料，用于诊断对象的肝癌的方法以及用于获得用于诊断肝癌的所需信息的方法 物体。

公开(公告)号：KR1020140079255A

公开(公告)日：2014-06-26

申请号：KR1020130041965

申请日：2013-04-17

Applicant: 삼성전자주식회사

Inventor： 박경희 ,  용예령 ,  강현주 ,  김가희 ,  박동현 ,  이묘용

IPC: G01N33/574 ,  C12Q1/68 ,  C12N15/11 ,  G01N33/53

CPC classification number: G01N33/57415 ,  C12N15/11 ,  C12Q1/6886 ,  C12Q2600/178 ,  G01N33/5308 ,  G01N2033/57403

Abstract: A breast cancer can be diagnosed early with a minimum invasive method and high convenience of a patient using a composition and a kit for diagnosing the breast cancer including: one or more micro RNAs which are selected from a group comprising hsa-miR-126, hsa-miR-23a, hsa-miR-24, hsa-miR-19b, hsa-miR-103, hsa-miR-142-3p, hsa-miR-144, hsa-miR-15a, hsa-miR-185, hsa-miR-93, and hsa-miR-30c contained in a vesicle; or polynucleotide which is in the same or in complementary relations with a fragment of the micro RNA. Also, the breast cancer can be diagnosed using a method for diagnosing the breast cancer and a method for obtaining information required for the diagnosis of the breast cancer using the composition and the kit.

Abstract translation: 可以使用组合物和用于诊断乳腺癌的试剂盒的最小侵入性方法和患者的高度方便性来早期诊断乳腺癌，包括：一种或多种选自包含hsa-miR-126，hsa的微RNA -miR-23a，hsa-miR-24，hsa-miR-19b，hsa-miR-103，hsa-miR-142-3p，hsa-miR-144，hsa-miR-15a，hsa-miR-185，hsa -miR-93和hsa-miR-30c; 或与微RNA片段相同或互补关系的多核苷酸。 此外，可以使用用于诊断乳腺癌的方法诊断乳腺癌，以及使用该组合物和试剂盒获得乳腺癌诊断所需的信息的方法。

公开(公告)号：KR1020140045844A

公开(公告)日：2014-04-17

申请号：KR1020120112094

申请日：2012-10-09

Applicant: 삼성전자주식회사

Inventor： 강현주 ,  용예령 ,  이묘용

IPC: G01N33/52 ,  G01N33/58

CPC classification number: G01N21/6486 ,  G01N21/64 ,  G01N21/6428 ,  G01N33/582

Abstract: According to a composition for monitoring vesicles in samples, a kit and a method for monitoring vesicles in samples using the same, a monitoring of the process can be performed, and the composition can be used as an internal control group and for quality assurance of samples, and track vesicles. [Reference numerals] (AA,EE) Sample-1; (BB,FF) Sample -2; (CC,GG) Sample -3; (DD,HH) Sample -4

Abstract translation: 根据用于监测样品中的囊泡的组合物，试剂盒和使用其的样品中的囊泡的方法，可以进行该过程的监测，并且该组合物可以用作内部对照组并用于样品的质量保证 ，跟踪小泡。 （标号）（AA，EE）Sample-1; （BB，FF）样品-2; （CC，GG）样品-3; （DD，HH）样品-4

公开(公告)号：KR1020140036857A

公开(公告)日：2014-03-26

申请号：KR1020120103503

申请日：2012-09-18

Applicant: 삼성전자주식회사

Inventor： 강현주 ,  용예령 ,  이묘용

IPC: G01N33/52 ,  G01N33/58 ,  G01N33/68

CPC classification number: G01N21/6486 ,  G01N33/582

Abstract: The present invention relates to a composition and a kit for detecting a vesicle and a method for analyzing a vesicle using the same. According to the composition, the kit, and the method, detection deviation due to the kind of a detection target or external protein contamination can be reduced by directly detecting microvesicles. Moreover, microvesicles can be quickly and effectively detected through a simple process. In addition, surface protein of microvesicles can be quickly and effectively identified through a simple process and ligands combined with microvesicles can be screened.

Abstract translation: 本发明涉及一种用于检测囊泡的组合物和试剂盒，以及使用其的囊泡分析方法。 根据组合物，试剂盒和方法，可以通过直接检测微泡来减少由于检测对象的种类或外部蛋白质污染引起的检测偏差。 此外，可以通过简单的过程快速有效地检测微泡。 此外，微泡的表面蛋白可以通过简单的方法快速有效地鉴定，并且可以筛选与微泡结合的配体。

公开(公告)号：KR1020130080307A

公开(公告)日：2013-07-12

申请号：KR1020120001145

申请日：2012-01-04

Applicant: 삼성전자주식회사

Inventor： 박종면 ,  김명순 ,  용예령

IPC: C12Q1/68 ,  C12Q1/02 ,  B01D17/038

CPC classification number: B01L3/502753 ,  B01L3/502738 ,  B01L7/52 ,  B01L2300/0806 ,  B01L2300/0864 ,  B01L2300/1811 ,  B01L2300/1827 ,  B01L2300/1861 ,  B01L2300/1872 ,  B01L2400/0677 ,  C12N1/08 ,  C12Q1/6844

Abstract: PURPOSE: A microfluidic device is provided to efficiently isolate a target material from two or more materials with different density and to efficiently amplify nucleic acids in an emulsion. CONSTITUTION: A microfluidic device comprises: a disk-shaped rotational body; first chambers which are separately arranged from the center of the body in a centrifugal force direction; a second chamber (20) with upper outlet parts (24a) and a lower outlet part (26a) which is separated from the upper outlet parts in a centrifugal force direction; and third chambers (30) which are linked to the upper outlet parts and the lower outlet part of the second chamber for communication by fluids. The microfluidic device is able to control the flow of a fluid for isolating a target material from two or more materials with different density using a centrifugal force and torque.

Abstract translation: 目的：提供微流体装置以有效地从不同密度的两种或多种材料中分离靶物质，并有效地扩增乳剂中的核酸。 构成：微流体装置包括：盘状转动体; 在离心力方向上与主体的中心分开设置的第一室; 具有上部出口部分（24a）和下部出口部分（26a）的第二室（20），其在离心力方向上与上部出口部分分离; 和第三室（30），其连接到第二室的上部出口部分和下部出口部分，用于与流体连通。 微流体装置能够使用离心力和扭矩来控制用于将目标材料与两种或更多种具有不同密度的材料隔离的流体的流动。