소포 중 폴리뉴클레오티드 및 인테그린 단백질의 용도
    1.
    发明公开
    소포 중 폴리뉴클레오티드 및 인테그린 단백질의 용도 审中-实审
    多聚核苷酸和蛋白质内的蛋白质的使用

    公开(公告)号:KR1020150007878A

    公开(公告)日:2015-01-21

    申请号:KR1020130082465

    申请日:2013-07-12

    Abstract: The present invention relates to a composition and a kit for diagnosing breast cancer, wherein microRNA or a polynucleotide which is the same as or is complementary to the fragment thereof and an integrin protein or a material specifically bonding to the fragment thereof which are contained in a vesicle are included. The present invention also relates to a method for diagnosing breast cancer using the same and obtaining information needed to diagnose breast cancer. Breast cancer can be diagnosed early in a minimally invasive manner, and patient convenience can be improved.

    Abstract translation: 本发明涉及用于诊断乳腺癌的组合物和试剂盒,其中微RNA或与其片段相同或互补的多核苷酸和整合素蛋白质或与其片段特异性结合的材料,其包含在 包括囊泡。 本发明还涉及使用该乳腺癌诊断乳腺癌并获得诊断乳腺癌所需的信息的方法。 可以以微创方式早期诊断乳腺癌,并且可以改善患者的便利性。

    2 이상의 히드록시를 갖는 기 또는 쌍성이온성 기를 포함하는 중합체 및 그의 용도
    2.
    发明公开
    2 이상의 히드록시를 갖는 기 또는 쌍성이온성 기를 포함하는 중합체 및 그의 용도 审中-实审
    包含至少两个或两个或两个以上的组的聚合物及其用途

    公开(公告)号:KR1020130009557A

    公开(公告)日:2013-01-23

    申请号:KR1020110115926

    申请日:2011-11-08

    CPC classification number: C08F220/28 C08F220/56 C08F2220/282 G01N33/54353

    Abstract: PURPOSE: A polymer including zwitterionic group or a group having at least two hydroxy groups and a use thereof are provided to specifically combine with specific biomolecules. CONSTITUTION: A polymer comprises one or more recurring units selected from chemical formula M1 and one or more recurring units selected from chemical formula M2. Here, R1, R3, R4 and R6 are respectively indicate single bond or substituted or non-substituted C1-6 alkyl, R2 and R5 are respectively indicate H, halo or substituted or non-substituted C1-6 alkyl. A1 and A2 are respectively indicate-NH-, and -O- or -O - (CO) -. X and Y are respectively selected from radical having two or more hydroxy, zwitterionic, PEG and a material which specifically unites with the biomolecule.

    Abstract translation: 目的:提供包含两性离子基团或具有至少两个羟基的基团的聚合物及其用途,以特异性地与特定的生物分子组合。 构成:聚合物包含一个或多个选自化学式M1的重复单元和一个或多个选自化学式M2的重复单元。 这里,R 1,R 3,R 4和R 6分别表示单键或取代或未取代的C 1-6烷基,R 2和R 5分别表示H,卤素或取代或未取代的C 1-6烷基。 A1和A2分别表示-NH-和-O-或-O - (CO) - 。 X和Y分别选自具有两个或多个羟基,两性离子,PEG和与生物分子特异性结合的材料的基团。

    소포 중 폴리뉴클레오티드를 포함하는 유방암 진단용 조성물 및 키트, 및 이를 이용한 유방암 진단 방법
    4.
    发明公开
    소포 중 폴리뉴클레오티드를 포함하는 유방암 진단용 조성물 및 키트, 및 이를 이용한 유방암 진단 방법 审中-实审
    用于诊断包括在囊内的多核苷酸的乳腺癌的组合物和试剂盒,以及用于诊断使用其的乳腺癌的方法

    公开(公告)号:KR1020140079255A

    公开(公告)日:2014-06-26

    申请号:KR1020130041965

    申请日:2013-04-17

    Abstract: A breast cancer can be diagnosed early with a minimum invasive method and high convenience of a patient using a composition and a kit for diagnosing the breast cancer including: one or more micro RNAs which are selected from a group comprising hsa-miR-126, hsa-miR-23a, hsa-miR-24, hsa-miR-19b, hsa-miR-103, hsa-miR-142-3p, hsa-miR-144, hsa-miR-15a, hsa-miR-185, hsa-miR-93, and hsa-miR-30c contained in a vesicle; or polynucleotide which is in the same or in complementary relations with a fragment of the micro RNA. Also, the breast cancer can be diagnosed using a method for diagnosing the breast cancer and a method for obtaining information required for the diagnosis of the breast cancer using the composition and the kit.

    Abstract translation: 可以使用组合物和用于诊断乳腺癌的试剂盒的最小侵入性方法和患者的高度方便性来早期诊断乳腺癌,包括:一种或多种选自包含hsa-miR-126,hsa的微RNA -miR-23a,hsa-miR-24,hsa-miR-19b,hsa-miR-103,hsa-miR-142-3p,hsa-miR-144,hsa-miR-15a,hsa-miR-185,hsa -miR-93和hsa-miR-30c; 或与微RNA片段相同或互补关系的多核苷酸。 此外,可以使用用于诊断乳腺癌的方法诊断乳腺癌,以及使用该组合物和试剂盒获得乳腺癌诊断所需的信息的方法。

    시료 중 소포를 안정화시키는 방법
    10.
    发明公开
    시료 중 소포를 안정화시키는 방법 审中-实审
    用于在样品中稳定VESICLE的方法

    公开(公告)号:KR1020150052667A

    公开(公告)日:2015-05-14

    申请号:KR1020130134363

    申请日:2013-11-06

    CPC classification number: G01N1/405 G01N2015/0065 Y10T436/25375

    Abstract: 시료중 소포를안정화시키는방법및 이에사용되는조성물을제공한다. 이에의하면, 시료중 소포를안정화시켜소포의수득률을증가시키고소포의막 또는표면단백질의상태를유지할수 있다.

    Abstract translation: 本发明提供一种用于稳定样品中囊泡的方法和用于其中的组合物,其中所述方法包括以下步骤:将包含囊泡的样品与螯合剂混合以稳定囊泡; 并从样品中分离囊泡。 因此,本发明稳定了样品中的囊泡,以增加囊泡的产量并保持蛋白质在膜或膜囊表面上的状态。

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