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11.发明公开인동등, 우방자 및 황금 추출물을 유효성분으로 하는 염증, 통증 및 가래의 예방, 개선 또는 치료를 위한 조성물 无效LONICERAE CAULIS的组成，ARCTII FRUCTUS SEMEN和SCUTELLARIAE RADIX提取物用于治疗炎症，疼痛和SPUTUM
公开(公告)号：KR1020150051635A
公开(公告)日：2015-05-13
申请号：KR1020130133363
申请日：2013-11-05
Applicant: 유한회사한풍제약
IPC: A61K36/35 , A61K36/28 , A61K36/539 , A61P29/00
Abstract: 본발명은염증, 통증및 가래의예방, 개선또는치료를위한조성물에관한것으로, 상세하게는인동등, 우방자및 황금추출물을유효성분으로함유하는염증, 통증및 가래의예방, 개선또는치료를위한조성물에관한것이다. 본발명은인동등 3~15 중량부, 우방자 1~5 중량부의혼합추출물분말과황금 4~20 중량부의추출물분말을 1:1 ~ 1:3 중량비로혼합한것을기술적특징으로하고있다. 본발명은소염효능, 과민통, 이질통및 포르말린유도성통증을진통하는효능과, 거담효능을보유하고있다. 본발명은염증동물모델, 과민통동물모델과, 이질통동물모델및 거담동물모델을이용하여실험한결과에기반한, 염증, 통증및 가래의예방, 개선또는치료를위한조성물에관한것이다.
Abstract translation: 本发明涉及用于预防，缓解或治疗炎症，疼痛和痰液的组合物，更具体地说，涉及含有金银花，琵琶果实和黄芩提取物的组合物，作为预防，缓解或治疗炎症的活性成分， 疼痛和痰。 本发明包含作为技术特征的混合提取物粉末，其由3-15重量份金银花和1-5重量份的水果组成，并且提取粉末由4-20重量份的黄芩组成， 比例为1：1至1：3。 本发明具有减轻炎症，痛觉过敏，异常性疼痛，福尔马林引起的疼痛和排出痰的作用。 本发明涉及基于使用关于炎症，痛觉过敏，异常性疼痛和痰的动物模型的实验结果来预防，缓解或治疗炎症，疼痛和痰的组合物。
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公开(公告)号：KR101550285B1
公开(公告)日：2015-09-07
申请号：KR1020140063183
申请日：2014-05-26
Applicant: 유한회사한풍제약
IPC: A23L33/00 , A61K36/258
Abstract: 본발명은홍삼(C.A.Meyer) 추출물및 복분자(Miquel) 추출물을유효성분으로함유하는세포활성화효능을갖는조성물에관한것이다. 구체적으로상기세포활성화효능은, 세포생존율, DNA 상해에대한회복, 세포고사의저해, 비주기성 DNA 합성, DNA 절단감소율, 저분자량의 DNA 함량감소, p53 단백질의발현량감소및 p53 의존성단백질의발현량감소를촉진하는기능을포함하는것을기술적특징으로하고있다.
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公开(公告)号：KR101550280B1
公开(公告)日：2015-09-07
申请号：KR1020140063196
申请日：2014-05-26
Applicant: 유한회사한풍제약
IPC: A23L33/00 , A61K36/258
Abstract: 본발명은홍삼(Panax ginseng C.A.Meyer) 추출물및 포도(Vitis vinifera) 추출물을유효성분으로함유하는세포활성화효능을갖는조성물에관한것이다. 구체적으로상기세포활성화효능은, 세포생존율, DNA 상해에대한회복, 세포고사의저해, 비주기성 DNA 합성, DNA 절단감소율, 저분자량의 DNA 함량감소, p53 단백질의발현량감소및 p53 의존성단백질의발현량감소를촉진하는기능을포함하는것을기술적특징으로하고있다.
Abstract translation: 本发明涉及具有含红参（人参C.A.Meyer）提取物，葡萄（葡萄）一个细胞活化效果提取物作为活性成分的组合物。 具体地，细胞活化潜能，细胞生存力，对于损伤DNA回收，抑制细胞凋亡，非周期的DNA合成，DNA裂解减少，低分子量的降低DNA含量，表达降低量，和p53蛋白的p53依赖性蛋白质的表达 并促进血量减少的功能。
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公开(公告)号：KR1020140074267A
公开(公告)日：2014-06-17
申请号：KR1020140063196
申请日：2014-05-26
Applicant: 유한회사한풍제약
IPC: A23L33/00 , A61K36/258
CPC classification number: A23L33/00
Abstract: The present invention relates to a composite having cell activation efficiency which includes a Panax ginseng C.A.Meyer extract and a Vitis vinifera extract as an active component. More specifically, the cell activation efficiency comprises functions which promote a cell survival rate, recovery for DNA injury, inhibition of cell apoptosis, aperiodicity DNA synthesis, a DNA cut reducing rate, the reduction of DNA contents of a low molecular compound, the reduction of an expression ratio of p53 protein, and the reduction of an expression ratio of p53 dependence protein.
Abstract translation: 本发明涉及一种具有细胞活化效率的复合物，其包括人参C.A.Meyer提取物和作为活性成分的葡萄提取物。 更具体地，细胞活化效率包括促进细胞存活率，DNA损伤恢复，细胞凋亡抑制，非周期性DNA合成，DNA切割降低速率，降低低分子化合物的DNA含量的功能 p53蛋白的表达率以及p53依赖性蛋白表达率的降低。
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Patent Agency Ranking16.发明授权
公开(公告)号：KR101319866B1
公开(公告)日：2013-10-18
申请号：KR1020130034232
申请日：2013-03-29
Applicant: 유한회사한풍제약
IPC: A61K36/25 , A61K36/732 , A61K36/232 , A61K36/906
CPC classification number: A61K36/25 , A23L33/105 , A23V2002/00 , A61K36/232 , A61K36/31 , A61K36/732 , A61K36/78 , A61K36/9068 , A61K2236/00 , A61K2236/39 , A61K2300/00 , A23V2200/30 , A23V2200/306 , A23V2200/316 , A23V2250/21
Abstract: PURPOSE: A composition for osteoarthritis and rheumatoid arthritis prevention and treatment is provided to have no toxic in the rat of chondrocyte and macrophage and prevent the expression of pro-inflammatory cytokines. CONSTITUTION: A composition for osteoarthritis and rheumatoid arthritis prevention and treatment is made after mixing 150 parts by weight of kalopanax pictus, 650-750 parts by weight of quince, 50-150 parts by weight of angelica sinensis, 50-150 parts by weight of ginger, 50-150 parts by weight of raphanus sativus, 150-250 parts by weight of saururus chinensis or dried mixed extracts from the ingredients above. And the extracts are active ingredients to the composition. The composition has a function for preventing inflammatory cytokine and matrix metalloproteinase (MMPs), inflammation and pain and normalizing the structure of joint and enhancing the activity of chondrogenesis factor.
Abstract translation: 目的：提供一种用于骨关节炎和类风湿关节炎预防和治疗的组合物，用于在软骨细胞和巨噬细胞大鼠中无毒性，并预防促炎细胞因子的表达。 构成：在将150重量份的kalopanax pictus，650-750重量份的茜素，50-150重量份当归，50-150重量份的当归，混合后，进行骨关节炎和类风湿关节炎的预防和治疗组合物 姜，50-150重量份的红萝卜，150-250重量份的中华葫芦或上述成分的干混合提取物。 提取物是组合物的活性成分。 该组合物具有预防炎性细胞因子和基质金属蛋白酶（MMPs），炎症和疼痛并使关节结构正常化并增强软骨形成因子活性的功能。
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公开(公告)号：KR101758639B1
公开(公告)日：2017-07-17
申请号：KR1020160038720
申请日：2016-03-30
Applicant: 유한회사한풍제약
IPC: A61K36/355 , A61K36/28 , A61K36/539 , A23L1/30
Abstract: 본발명은인동등, 우방자및 황금을유효성분으로하는호흡기질환의예방, 개선또는치료를위한조성물에관한것이다. 특히, 염증, 통증, 가래, 발열및 기관지수축을예방, 개선또는치료를위한조성물에관한것이다. 본발명에따른조성물은인동등 3~15 중량부, 우방자 1~5 중량부의혼합추출물분말과황금 4~20 중량부의추출물분말을 1:1 ~ 1:3 중량비로혼합한것을유효성분으로포함하는것을기술적특징으로하고있다.
Abstract translation: 本发明涉及用于预防，改善或治疗呼吸系统疾病如呼吸器官炎症，溃疡和金的组合物。 具体而言，本发明涉及用于预防，改善或治疗炎症，疼痛，痰，发热和支气管收缩的组合物。 根据本发明的组合物通过将3至15重量份的马铃薯粉末，1至5重量份的混合粉末和4至20重量份的提取物粉末以1：1至1：3的重量比混合， 作为技术特点。
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18.发明公开대추, 복분자, 애엽, 황금 및 Rg2 강화 홍삼을 유효성분으로 함유하는 골다골증 예방, 개선 또는 치료를 위한 조성물 无效一种包含ZIZYPHUS JUJUBA，RUBUS COREANUS，ARTEMISIA PRINCEPS VAR的药物。 ORIENTALIS，SCUTELLARIA BAICALENSIS和PANAX GINSENG用于治疗或预防OSTEOPOROSIS
公开(公告)号：KR1020150099043A
公开(公告)日：2015-08-31
申请号：KR1020140020515
申请日：2014-02-21
Applicant: 유한회사한풍제약
IPC: A61K36/725 , A61K36/73 , A61K36/258 , A61P19/10
CPC classification number: A61K36/725 , A23V2200/306 , A61K36/539 , A61K36/73
Abstract: 본 발명은 대추, 복분자, 애엽, 황금 및 Rg2 강화 홍삼을 유효성분으로 함유하는 골다공증 예방, 개선 또는 치료를 위한 조성물에 관한 것이다.
더욱 상세하게는, TNF-α 및 IL-1β를 감소시키고, iNOS 및 MMPs의 발현을 억제하며, 파골세포의 분화를 억제하고, 조골세포 분화인자의 발현을 증가시키며, 골다공증 유도 마우스 모델에서 골밀도를 증가시키는 효능이 있는 골다공증 예방, 개선 또는 치료를 위한 조성물에 관한 것이다.Abstract translation: 本发明涉及含有枣子，芦苇，白花蒿， 东方药，黄芩和Rg2增强人参作为预防或治疗骨质疏松症的有效成分，更具体地说涉及一种预防或治疗骨质疏松症的组合物，其具有降低TNF-α和IL-1β的作用，抑制iNOS的表达 和MMPs，抑制破骨细胞的分化，增加成骨细胞分化因子的表达，并增加骨质疏松诱导的小鼠模型中的骨密度。
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公开(公告)号：KR1020140081769A
公开(公告)日：2014-07-01
申请号：KR1020140063183
申请日：2014-05-26
Applicant: 유한회사한풍제약
IPC: A23L33/00 , A61K36/258
CPC classification number: A23L33/00
Abstract: The present invention relates to a composition which has a cell activation effect by containing a red ginseng (Panax ginseng C.A. Meyer) extract and a raspberry (Rubus coreanus Miquel) extract as effective components. Specifically, the cell activation effect includes a function which facilitates cell viability, restoration against DNA damage, hindrance of apoptosis, non-periodic DNA synthesis, DNA cut reduction rate, DNA content reduction of a low molecular weight, expression level of a p53 protein, and expression reduction of a p53 dependent protein.
Abstract translation: 本发明涉及一种含有红参（Panax ginseng C.A.Meyer）提取物和覆盆子（Rubus coreanus Miquel）提取物作为有效成分的具有细胞活化作用的组合物。 具体而言，细胞活化效果包括促进细胞活力，DNA损伤恢复，细胞凋亡阻碍，非周期性DNA合成，DNA切割减少率，低分子量的DNA含量降低，p53蛋白的表达水平的功能， 和p53依赖性蛋白的表达减少。
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公开(公告)号：KR100407764B1
公开(公告)日：2003-12-01
申请号：KR1020010017455
申请日：2001-04-02
Applicant: 유한회사한풍제약
IPC: C07K1/12
Abstract: PURPOSE: A method for producing silk-thread peptide is provided, thereby rapidly and cheaply producing the silk-thread peptide, which has a molecular weight of 500-10000 and 100% solubility at pH 4 to 9, in higher yield. CONSTITUTION: The method for producing silk-thread peptide comprises the steps of: inserting 1 part by weight of silk-thread protein into a solution containing 3 to 7 parts by weight of potassium chloride, 1.5 to 3.5 parts by volume(v/w) of ethanol, and 3 to 7 parts by volume(v/w) of water, and heating the solution at 85 to 95 deg. C for 1 to 3 hours to dissolve the silk-thread protein; dialyzing the silk-thread dissolved solution at 20 to 65 deg. C for 25 to 60 hours to remove salts; and adding 0.1 to 3.0%(w/v) of bromelain into 0.1 to 10.0%(w/v) of the silk-thread protein solution and reacting them at 25 to 30 deg. C for 1 to 5 hours.
Abstract translation: 目的：提供一种生产丝线肽的方法，由此以较高的收率快速和便宜地生产具有500-10000的分子量和在pH 4至9的100％溶解度的丝线肽。 构成：丝线肽的生产方法包括以下步骤：将1重量份丝线蛋白质加入含有3至7重量份氯化钾，1.5至3.5体积份（v / w） 的乙醇和3至7体积份（v / w）的水，并将溶液在85至95℃加热。 加热1至3小时以溶解丝线蛋白质; 在20至65℃下透析丝线溶解的溶液。 C 25-60小时以除去盐; 并将0.1-3.0％（w / v）菠萝蛋白酶加入0.1-10.0％（w / v）丝线蛋白质溶液中并在25-30℃下使它们反应。 C 1至5小时。
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