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公开(公告)号：KR1020110090283A
公开(公告)日：2011-08-10
申请号：KR1020100009975
申请日：2010-02-03
Applicant: 전북대학교산학협력단 , 유한회사한풍제약
IPC: A61K36/744 , A61K36/232 , A61K36/538 , A61P1/02
Abstract: PURPOSE: A composition containing plant extract for periodontal diseases is provided to reduce inflammation due to reduction of IL-1beta and TNF-alpha secretion. CONSTITUTION: A composition for preventing and treating periodontal diseases contains extract prepared by isolating Gardeniae Fructus, Angelicae gigantis Radix, and Nepetae Spica using eight times of purified water at 80-100°C for three hours. The extract is used by filtering at 200 meshes and compressing less than 60 degrees Celsius. The composition further contains pharmaceutically acceptable excipient, binder, lubricant, disintegrant, coating agent, emulsifier, suspension agent, and injection solution. The composition is an oral or injection formulation.
Abstract translation: 目的：提供一种含有牙周病植物提取物的组合物，用于减少由于IL-1β和TNF-α分泌减少引起的炎症。 构成：用于预防和治疗牙周病的组合物含有通过使用八次纯水在80-100℃下分离栀子，当归和荆芥来制备提取物三小时。 提取物通过200目筛过滤并压缩低于60摄氏度来使用。 组合物还含有药学上可接受的赋形剂，粘合剂，润滑剂，崩解剂，包衣剂，乳化剂，悬浮剂和注射溶液。 组合物是口服或注射制剂。
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公开(公告)号：KR101132110B1
公开(公告)日：2012-04-05
申请号：KR1020100009975
申请日：2010-02-03
Applicant: 전북대학교산학협력단 , 유한회사한풍제약
IPC: A61K36/744 , A61K36/232 , A61K36/538 , A61P1/02
Abstract: PURPOSE: A composition containing plant extract for periodontal diseases is provided to reduce inflammation due to reduction of IL-1beta and TNF-alpha secretion. CONSTITUTION: A composition for preventing and treating periodontal diseases contains extract prepared by isolating Gardeniae Fructus, Angelicae gigantis Radix, and Nepetae Spica using eight times of purified water at 80-100°C for three hours. The extract is used by filtering at 200 meshes and compressing less than 60 degrees Celsius. The composition further contains pharmaceutically acceptable excipient, binder, lubricant, disintegrant, coating agent, emulsifier, suspension agent, and injection solution. The composition is an oral or injection formulation.
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3.发明公开대추, 복분자, 애엽, 황금 및 Rg2 강화 홍삼을 유효성분으로 함유하는 골다골증 예방, 개선 또는 치료를 위한 조성물 无效一种包含ZIZYPHUS JUJUBA，RUBUS COREANUS，ARTEMISIA PRINCEPS VAR的药物。 ORIENTALIS，SCUTELLARIA BAICALENSIS和PANAX GINSENG用于治疗或预防OSTEOPOROSIS
公开(公告)号：KR1020150099043A
公开(公告)日：2015-08-31
申请号：KR1020140020515
申请日：2014-02-21
Applicant: 유한회사한풍제약
IPC: A61K36/725 , A61K36/73 , A61K36/258 , A61P19/10
CPC classification number: A61K36/725 , A23V2200/306 , A61K36/539 , A61K36/73
Abstract: 본 발명은 대추, 복분자, 애엽, 황금 및 Rg2 강화 홍삼을 유효성분으로 함유하는 골다공증 예방, 개선 또는 치료를 위한 조성물에 관한 것이다.
더욱 상세하게는, TNF-α 및 IL-1β를 감소시키고, iNOS 및 MMPs의 발현을 억제하며, 파골세포의 분화를 억제하고, 조골세포 분화인자의 발현을 증가시키며, 골다공증 유도 마우스 모델에서 골밀도를 증가시키는 효능이 있는 골다공증 예방, 개선 또는 치료를 위한 조성물에 관한 것이다.Abstract translation: 本发明涉及含有枣子，芦苇，白花蒿， 东方药，黄芩和Rg2增强人参作为预防或治疗骨质疏松症的有效成分，更具体地说涉及一种预防或治疗骨质疏松症的组合物，其具有降低TNF-α和IL-1β的作用，抑制iNOS的表达 和MMPs，抑制破骨细胞的分化，增加成骨细胞分化因子的表达，并增加骨质疏松诱导的小鼠模型中的骨密度。
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公开(公告)号：KR1020140081769A
公开(公告)日：2014-07-01
申请号：KR1020140063183
申请日：2014-05-26
Applicant: 유한회사한풍제약
IPC: A23L33/00 , A61K36/258
CPC classification number: A23L33/00
Abstract: The present invention relates to a composition which has a cell activation effect by containing a red ginseng (Panax ginseng C.A. Meyer) extract and a raspberry (Rubus coreanus Miquel) extract as effective components. Specifically, the cell activation effect includes a function which facilitates cell viability, restoration against DNA damage, hindrance of apoptosis, non-periodic DNA synthesis, DNA cut reduction rate, DNA content reduction of a low molecular weight, expression level of a p53 protein, and expression reduction of a p53 dependent protein.
Abstract translation: 本发明涉及一种含有红参（Panax ginseng C.A.Meyer）提取物和覆盆子（Rubus coreanus Miquel）提取物作为有效成分的具有细胞活化作用的组合物。 具体而言，细胞活化效果包括促进细胞活力，DNA损伤恢复，细胞凋亡阻碍，非周期性DNA合成，DNA切割减少率，低分子量的DNA含量降低，p53蛋白的表达水平的功能， 和p53依赖性蛋白的表达减少。
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公开(公告)号：KR101550285B1
公开(公告)日：2015-09-07
申请号：KR1020140063183
申请日：2014-05-26
Applicant: 유한회사한풍제약
IPC: A23L33/00 , A61K36/258
Abstract: 본발명은홍삼(C.A.Meyer) 추출물및 복분자(Miquel) 추출물을유효성분으로함유하는세포활성화효능을갖는조성물에관한것이다. 구체적으로상기세포활성화효능은, 세포생존율, DNA 상해에대한회복, 세포고사의저해, 비주기성 DNA 합성, DNA 절단감소율, 저분자량의 DNA 함량감소, p53 단백질의발현량감소및 p53 의존성단백질의발현량감소를촉진하는기능을포함하는것을기술적특징으로하고있다.
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Patent Agency Ranking
公开(公告)号：KR101550280B1
公开(公告)日：2015-09-07
申请号：KR1020140063196
申请日：2014-05-26
Applicant: 유한회사한풍제약
IPC: A23L33/00 , A61K36/258
Abstract: 본발명은홍삼(Panax ginseng C.A.Meyer) 추출물및 포도(Vitis vinifera) 추출물을유효성분으로함유하는세포활성화효능을갖는조성물에관한것이다. 구체적으로상기세포활성화효능은, 세포생존율, DNA 상해에대한회복, 세포고사의저해, 비주기성 DNA 합성, DNA 절단감소율, 저분자량의 DNA 함량감소, p53 단백질의발현량감소및 p53 의존성단백질의발현량감소를촉진하는기능을포함하는것을기술적특징으로하고있다.
Abstract translation: 本发明涉及具有含红参（人参C.A.Meyer）提取物，葡萄（葡萄）一个细胞活化效果提取物作为活性成分的组合物。 具体地，细胞活化潜能，细胞生存力，对于损伤DNA回收，抑制细胞凋亡，非周期的DNA合成，DNA裂解减少，低分子量的降低DNA含量，表达降低量，和p53蛋白的p53依赖性蛋白质的表达 并促进血量减少的功能。
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公开(公告)号：KR1020140074267A
公开(公告)日：2014-06-17
申请号：KR1020140063196
申请日：2014-05-26
Applicant: 유한회사한풍제약
IPC: A23L33/00 , A61K36/258
CPC classification number: A23L33/00
Abstract: The present invention relates to a composite having cell activation efficiency which includes a Panax ginseng C.A.Meyer extract and a Vitis vinifera extract as an active component. More specifically, the cell activation efficiency comprises functions which promote a cell survival rate, recovery for DNA injury, inhibition of cell apoptosis, aperiodicity DNA synthesis, a DNA cut reducing rate, the reduction of DNA contents of a low molecular compound, the reduction of an expression ratio of p53 protein, and the reduction of an expression ratio of p53 dependence protein.
Abstract translation: 本发明涉及一种具有细胞活化效率的复合物，其包括人参C.A.Meyer提取物和作为活性成分的葡萄提取物。 更具体地，细胞活化效率包括促进细胞存活率，DNA损伤恢复，细胞凋亡抑制，非周期性DNA合成，DNA切割降低速率，降低低分子化合物的DNA含量的功能 p53蛋白的表达率以及p53依赖性蛋白表达率的降低。
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公开(公告)号：KR101528871B1
公开(公告)日：2015-06-16
申请号：KR1020120121991
申请日：2012-10-31
Applicant: 유한회사한풍제약
IPC: A61K36/258 , A61K36/87 , A61K36/282 , A23L33/00
Abstract: 본발명은홍삼(Panax ginseng C.A.Meyer) 추출물; 포도(Vitis vinifera), 쑥(Artemisia), 복분자(Rubus coreanus Miquel)로이루어진군에서선택된 1 종이상의추출물;을유효성분으로함유하는세포활성화효능을갖는조성물에관한것이다. 구체적으로상기세포활성화효능은, 세포생존율, DNA 상해에대한회복, 세포고사의저해, 비주기성 DNA 합성, DNA 절단감소율, 저분자량의 DNA 함량감소, p53 단백질의발현량감소및 p53 의존성단백질의발현량감소를촉진하는기능을포함하는것을기술적특징으로하고있다.
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公开(公告)号：KR1020140056714A
公开(公告)日：2014-05-12
申请号：KR1020120121991
申请日：2012-10-31
Applicant: 유한회사한풍제약
IPC: A61K36/258 , A61K36/87 , A61K36/282 , A23L33/00
CPC classification number: A61K36/258 , A61K36/282 , A61K36/87
Abstract: 본발명은홍삼(Panax ginseng C.A.Meyer) 추출물; 포도(Vitis vinifera), 쑥(Artemisia), 복분자(Rubus coreanus Miquel)로이루어진군에서선택된 1 종이상의추출물;을유효성분으로함유하는세포활성화효능을갖는조성물에관한것이다. 구체적으로상기세포활성화효능은, 세포생존율, DNA 상해에대한회복, 세포고사의저해, 비주기성 DNA 합성, DNA 절단감소율, 저분자량의 DNA 함량감소, p53 단백질의발현량감소및 p53 의존성단백질의발현량감소를촉진하는기능을포함하는것을기술적특징으로하고있다.
Abstract translation: 本发明涉及一种组合物，其包含一种或多种选自以下的提取物：人参（人参CAMeyer）提取物，葡萄（Vitis vinifera），艾蒿（艾蒿）和覆盆子（Rubus coreanus Miquel）作为活性成分， 并具有细胞活化作用。 特别地，本发明的细胞活化作用促进细胞活力; DNA损伤恢复; 抑制凋亡; 非定期DNA合成; DNA缺失率降低; 降低低分子量DNA含量; 并减少p53蛋白表达和p53依赖性蛋白表达。
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公开(公告)号：KR1020110090293A
公开(公告)日：2011-08-10
申请号：KR1020100009988
申请日：2010-02-03
Applicant: 전북대학교산학협력단 , 유한회사한풍제약
IPC: A61K36/718 , A61P1/02
CPC classification number: A61K36/718 , A23V2200/312 , A61K2236/331 , Y10S514/90
Abstract: PURPOSE: A composition containing Coptis japonica(Thunb.) extract is provided to reduce damage of gingival bone and to treat periodontitis. CONSTITUTION: A method for manufacturing a composition for treating periodontitis comprises: a step of extracting 100g of Coptis japonica(Thunb.) extract with 800 ml of purified water at 80-100°C for three hours; a step of filtering the extract at 200 meshes; a step of compressing under 60°C for concentration; and a step of mixing the extract, vitamin C, and vitamin E. The composition is an oral or injection formulation. The oral formulation is a granule, tablet, capsule, and liquid.
Abstract translation: 目的：提供含有黄连（Thunb。）提取物的组合物，以减少牙龈骨的损伤并治疗牙周炎。 构成：牙周炎治疗用组合物的制造方法，其特征在于，在80-100℃下，用800ml净化水提取100g黄连（Thunb。）提取物3小时; 在200目筛过滤提取物的步骤; 在60℃下压缩浓缩的步骤; 以及混合提取物，维生素C和维生素E的步骤。组合物是口服或注射制剂。 口服制剂是颗粒，片剂，胶囊和液体。
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