Abstract:
가스 하이드레이트의 상평형 측정을 연속적으로 수행할 수 있는 방법을 개시한다. 상기 상평형 측정 방법에서는 결정 표면에 걸리는 하중에 따라 공진 주파수가 달라지는 압전성 결정을 포함하는 센서의 압전성 결정 표면에 물 또는 수용액을 가하고, 이 센서를 가압 체임버에 넣은 후, 상평형 측정 대상 기체를 밀폐한 가압 체임버에 도입하고, 상기 가압 체임버 속의 상기 기체 압력과 상기 체임버의 온도 중 적어도 하나를 조절하면서 상기 기체와 물 또는 수용액이 상기 압전성 결정의 표면에 가스 하이드레이트를 형성하도록 한다. 이어서 상기 체임버의 온도를 높이면서 상기 압전성 결정의 공진 주파수의 변화를 직접 또는 간접적으로 감지함으로써 상기 가스 하이드레이트가 해리하는 첫번째 상평형점을 측정한 뒤, 상기 체임버에 상기 기체를 다시 가압하고 온도를 낮추어 가스 하이드레이트의 재형성을 촉진한다. 이어서 재형성된 가스 하이드레이트를 승온하여 해리시킴으로써 두번째 상평형점을 측정한다.
Abstract:
PURPOSE: A biosensor using the aggregation of magnetic nanoparticles and a detecting method using the same are provided to quickly and sensitively detect a target material. CONSTITUTION: A biosensor comprises: a substrate(100) with a receptor(200) which specifically reacts with a target material(300); a first magnetic nanoparticle(400) with the same receptor; a magnetic field supply unit which applies a magnetic field to the first magnetic nanoparticle; and a second magnetic particle(600) which aggregates with the first magnetic nanoparticle. The target material is an enzyme substrate, a ligand, an antigen, an antibody, a nucleotide, an amino acid, a peptide, a protein, a nucleic acid, lipid, carbohydrate, an organic compound, or an inorganic compound. The first and second magnetic nanoparticles are independently a ferromagnetic or paramagnetic nanoparticle.
Abstract:
PURPOSE: A method for measuring continuous phase equilibrium of gas hydrate using memory effect is provided to use a small amount of water drops or mixed solution drops, thereby reducing time in which a gas hydrate specimen reaches to phase equilibrium. CONSTITUTION: A method for measuring continuous phase equilibrium of gas hydrate using memory effect is as follows. Water or a solution is added on a piezoelectric crystal surface of a sensor including the piezoelectric crystal surface in which a resonant frequency becomes different according to a load being applied and the sensor is put into a pressure chamber. A gas is pressurized after closing a pressure chamber and the gas and the water or the solution form the gas hydrate on the piezoelectric crystal surface while controlling at least one of gas pressure or chamber temperature in the inside of the pressure chamber. A resonant frequency change of the piezoelectric crystal surface is directly or indirectly sensed while increasing the chamber temperature so that first phase equilibrium in which the gas hydrate is dissociated is measured. [Reference numerals] (AA) Resonant frequency(MHz); (BB) Water(fluid type); (CC) Gas-hydrate(solid type); (DD) Inspection time; (EE) 1hr
Abstract:
PURPOSE: A mass reinforcing method of gold nano-particles due to light irradiation, a biosensor, and biomolecule combining detection method using the same are provided to reinforce mass of the gold nano-particles by using an optical irradiation method. CONSTITUTION: A mass reinforcing method of gold nano-particles due to light irradiation comprises the following steps: irradiating a mixture including gold nano-particles(13) and reinforcing metal component(15) with light; and increasing the mass of the gold nano-particles by reducing thereof on the surface of the gold nano-particles. The light is ultraviolet ray. The metal reinforcing component is metallic ion. A bio molecular combining detection method comprises the following steps: reacting target bio molecular with bio sensors which detect physical property changes according to bondage of the target bio molecular; combining the gold nano-particle to the target bio molecular; dipping the bio sensor into a mixture which includes the metal reinforcing components and irradiating light; and detecting physical property change of the gold nano-particles.
Abstract:
A sensor and a method for detecting antigen-antibody reaction are provided to identify the binding of a fluorescence-unlabeled protein such as the binding of the antigen-antibody. A sensor for detecting antigen-antibody reaction is characterized in that a porous thin film is coated on a quartz crystal microbalance, wherein the porous thin film is a sol-gel porous thin film and includes an antigen or an antibody, or a protein non-specific binding inhibitor. To detect the protein binding, a porous thin film is coated on a microbalance, wherein the porous thin film has a specific protein binding portion. To detect the antigen-antibody reaction, weight change before and after the antigen-antibody reaction is detected by using the microbalance. Further, the antigen-antibody has non-fluorescence property.