Abstract:
PURPOSE: A novel compound isolated from Aspergillus sp. KMD901 is provided to be used as a anticancer agent. CONSTITUTION: An Aspergillus sp. strain(deposit number KCCM 11047P) is derived from marine deposit soil. A composition for preventing or treating cancer contains Aspergillus sp. strain, culture material of the strain, dried material or concentrate of the culture material, organic solvent extract which is obtained from the culture using ethyl acetate, alcohol of C1-C4, methylene chloride, ether, or chloroform, or fraction. A composition for preventing or treating cancer contains acetylaranotin of chemical formula 1, acetylapoaranotin of chemical formula 2, dehydro-deoxyapoaranotin of chemical formula 3 or pharmaceutically acceptable salt thereof as an active ingredient.
Abstract:
PURPOSE: A composition containing Lycoris aurea extract, fraction thereof, or compound isolated from the same for preventing or treating dementia is provided to apply in a single method and in a cocktail method with conventional therapeutic agent such as tacrine, donepezil, and rivastigmine. CONSTITUTION: A composition for preventing or treating dementia contains Lycoris aurea extract as an active ingredient. The Lycoris aurea extract is isolated using water or low alcohol of C1-C4. The Lycoris aurea extract is also an acetic acid ethyl fraction, butanol fraction, or mixture thereof. The composition for preventing or treating dementia contains lycoricidine of chemical formula 1, lycoricidinol of chemical formula 2, or pharmaceutically acceptable salt as an active ingredient. The dementia is Alzheimer's disease. A health food for preventing or treating dementia contains the composition.