公开(公告)号：EP1450161A3

公开(公告)日：2006-05-24

申请号：EP04010901.9

申请日：1993-03-24

Applicant: ABBOTT LABORATORIES

Inventor： Clark, Frederic L. ,  Clift, Gilbert ,  Hendrick, Kendall B. ,  Kanewske, William J. III. ,  Lagocki, Peter A. ,  Martin, Richard R. ,  Mitchell, James E. ,  Moore, Larry W. ,  Pennington, Charles D. ,  Walker, Edna S. ,  Smith, Jane B. ,  Tayi, Apparao ,  Vaught, James A. ,  Yost, David A. ,  Winter, Gary E. ,  Hance, Robert B. ,  Stanton, Alyn K. ,  Oleksak, Carl M. ,  Watkins, William E. III. ,  Vickstrom, Richard L. ,  Cloonan, Kevin M. ,  Wohlford Robert A. ,  Hills, David B. Jr. ,  Schrier, Paul R. ,  Rumbaugh, William

IPC: G01N35/02 ,  B65B7/00

CPC classification number: G01N21/0303 ,  B01L3/08 ,  B01L3/5025 ,  B01L3/5085 ,  B01L3/50853 ,  B01L9/06 ,  B01L2200/142 ,  B01L2200/16 ,  B01L2300/042 ,  B01L2300/043 ,  G01N21/253 ,  G01N33/5302 ,  G01N33/537 ,  G01N33/538 ,  G01N33/542 ,  G01N33/54313 ,  G01N35/0092 ,  G01N35/0099 ,  G01N35/025 ,  G01N35/026 ,  G01N35/1004 ,  G01N2001/007 ,  G01N2035/00287 ,  G01N2035/00356 ,  G01N2035/00386 ,  G01N2035/00455 ,  G01N2035/00475 ,  G01N2035/00495 ,  G01N2035/00524 ,  G01N2035/00752 ,  G01N2035/0093 ,  G01N2035/0405 ,  G01N2035/0436 ,  G01N2035/0441 ,  G01N2035/0443 ,  G01N2035/0444 ,  G01N2035/0448 ,  G01N2035/0453 ,  G01N2035/0465 ,  G01N2035/1025 ,  G01N2035/1076 ,  G01N2035/1086 ,  H01J49/04

Abstract: A method for controlling evaporation and contamination of reagents used in automated diagnostic systems is disclosed as well as an apparatus for opening and closing reagent containers contained within a reagent pack having cover and cap means for such controlling of evaporation and contamination. The method comprises (a) moving reagent packs containing reagents in closed reagent containers mounted in a reagent pack carousel to an opening and closing station, (b) forcing open the evaporatively closed reagent containers contained in the reagent pack by the opening and closing station, (c) locking in an open position the reagent containers cover and cap which is affixed to the reagent containers, (d) moving the locked open reagent containers from the opening and closing station on the reagent pack carousel to a position wherein the system has access to the reagents, (e) withdrawing reagents from the reagent containers for system use, (f) returning the reagent pack and reagent containers on the reagent pack carousel to the opening and closing station, (g) unlocking the lock open cover and cap of the reagent containers, (h) force closing the cover and cap of the reagent containers of the reagent pack, and (i) removing the reagent pack from the opening and closing station.

公开(公告)号：EP1537915A2

公开(公告)日：2005-06-08

申请号：EP05004222.5

申请日：1993-03-24

Applicant: ABBOTT LABORATORIES

Inventor： Clark, Federic L. ,  Clift, Gilbert ,  Hendrick, Kendall B. ,  Kanewske, William J. III. ,  Lagocki, Peter A. ,  Martin, Richard R. ,  Mitchell, James E. ,  Moore, Larry W. ,  Penningon, Charles D. ,  Walker, Edna S. ,  Smith, Jane B. ,  Tayi, Apparao ,  Vaught, James A. ,  Yost, David A. ,  Rumbaugh, William ,  Winter, Gary E. ,  Hance, Robert B. ,  Stanton, Alyn K. ,  Oleksak, Carl M. ,  Watkins, William E. III ,  Vickstrom, Richard L. ,  Cloonan, Kevin M. ,  Wohlford, Robert A. ,  Hills, David B. Jr. ,  Schrier, Paul R.

IPC: B01L3/00 ,  G01N35/02

CPC classification number: G01N21/0303 ,  B01L3/08 ,  B01L3/5025 ,  B01L3/5085 ,  B01L3/50853 ,  B01L9/06 ,  B01L2200/142 ,  B01L2200/16 ,  B01L2300/042 ,  B01L2300/043 ,  G01N21/253 ,  G01N33/5302 ,  G01N33/537 ,  G01N33/538 ,  G01N33/542 ,  G01N33/54313 ,  G01N35/0092 ,  G01N35/0099 ,  G01N35/025 ,  G01N35/026 ,  G01N35/1004 ,  G01N2001/007 ,  G01N2035/00287 ,  G01N2035/00356 ,  G01N2035/00386 ,  G01N2035/00455 ,  G01N2035/00475 ,  G01N2035/00495 ,  G01N2035/00524 ,  G01N2035/00752 ,  G01N2035/0093 ,  G01N2035/0405 ,  G01N2035/0436 ,  G01N2035/0441 ,  G01N2035/0443 ,  G01N2035/0444 ,  G01N2035/0448 ,  G01N2035/0453 ,  G01N2035/0465 ,  G01N2035/1025 ,  G01N2035/1076 ,  G01N2035/1086 ,  H01J49/04

Abstract: A reaction vessel suitable for multiple assay utilization within an automated, continuous and random access analytical system which allows for kitting of sample and reagents and physical transfer of the kitted reaction vessel to a process carousel is disclosed. The reaction vessel comprises multiple wells of various volume capacities, the multiple wells having openings on the same plane and depths extending from said plane. The reaction vessel has at least one cuvette, which extends substantially below the multiple wells and has an opening on the same plane as the multiple wells. The reaction vessel further comprises a transfer projection on a well bottom portion of the well on a first end portion of the reaction vessel, the cuvette projecting downward from a second end portion of the reaction vessel.

Abstract translation: 公开了一种适用于在自动化，连续和随机存取分析系统中多次测定利用的反应容器，其允许样品和试剂的起球以及将起动的反应容器物理转移到工艺转盘。 反应容器包括多个不同体积容积的孔，多个孔在同一平面上具有开口并且从所述平面延伸的深度。 反应容器具有至少一个比色皿，其大致在多个孔下方延伸，并且在与多个孔相同的平面上具有开口。 反应容器还包括在反应容器的第一端部上的井的井底部上的转移突起，反应杯从反应容器的第二端部向下突出。

公开(公告)号：EP1450163A9

公开(公告)日：2004-12-29

申请号：EP04010902.7

申请日：1993-03-24

Applicant: ABBOTT LABORATORIES

Inventor： Clark, Frederic L. ,  Clift, Gilbert ,  Hendrick, Kendall B. ,  Kanewske, William J. III. ,  Lagocki, Peter A. ,  Martin, Richard R. ,  Mitchell, James E. ,  Moore, Larry W. ,  Pennington, Charles D. ,  Walker, Edna S. ,  Smith, Jane B. ,  Tayi, Apparao ,  Vaught, James A. ,  Yost, David A. ,  Rumbaugh, William ,  Winter, Gary E. ,  Hance, Robert B. ,  Stanton, Alyn K. ,  Oleksak, Carl M. ,  Watkins, William E. III. ,  Vickstrom, Richard L. ,  Cloonan, Kevin M. ,  Wohlford Robert A. ,  Hills, David B. Jr. ,  Schrier, Paul R.

IPC: G01N35/02 ,  G01N35/10 ,  F04B53/00

CPC classification number: G01N21/0303 ,  B01L3/08 ,  B01L3/5025 ,  B01L3/5085 ,  B01L3/50853 ,  B01L9/06 ,  B01L2200/142 ,  B01L2200/16 ,  B01L2300/042 ,  B01L2300/043 ,  G01N21/253 ,  G01N33/5302 ,  G01N33/537 ,  G01N33/538 ,  G01N33/542 ,  G01N33/54313 ,  G01N35/0092 ,  G01N35/0099 ,  G01N35/025 ,  G01N35/026 ,  G01N35/1004 ,  G01N2001/007 ,  G01N2035/00287 ,  G01N2035/00356 ,  G01N2035/00386 ,  G01N2035/00455 ,  G01N2035/00475 ,  G01N2035/00495 ,  G01N2035/00524 ,  G01N2035/00752 ,  G01N2035/0093 ,  G01N2035/0405 ,  G01N2035/0436 ,  G01N2035/0441 ,  G01N2035/0443 ,  G01N2035/0444 ,  G01N2035/0448 ,  G01N2035/0453 ,  G01N2035/0465 ,  G01N2035/1025 ,  G01N2035/1076 ,  G01N2035/1086 ,  H01J49/04

Abstract: A bubble flushing aspirating and dispensing syringe having precision and volumetric accuracy, particularly for use in an automated, continuous and random access analytical system, is disclosed. The syringe comprises a piston (124) within a bore (128), the bore having seal means at a first end and a closed end (130) at a second end, wherein the piston forms an annulus (138) with the bore wall and seal means, and is capable of reciprocating therein. Fluid inlet (134) and fluid outlet (136) means are in communication with the annulus (138) and bore, the fluid inlet and fluid outlet means being located between the seal means and the bore closed end. A fluid source is in communication with the inlet means and a fluid conduit is in communication with the outlet means and an open-ended release tip. A drive means is connected to the piston for reciprocating the piston within the bore. As a result, fluid from the inlet, when connected to a fluid supply, flows through the annulus (138) around the sides of the piston and out through the fluid outlet to the open-ended tip, thereby creating a cross-flow pattern in the annulus (138) around the piston as it reciprocates in the bore to flush bubbles through the outlet.

公开(公告)号：EP1450163A8

公开(公告)日：2004-11-10

申请号：EP04010902.7

申请日：1993-03-24

Applicant: ABBOTT LABORATORIES

Inventor： Clark, Frederic L. ,  Clift, Gilbert ,  Hendrick, Kendall B. ,  Kanewske, William J. III. ,  Lagocki, Peter A. ,  Martin, Richard R. ,  Mitchell, James E. ,  Moore, Larry W. ,  Pennington, Charles D. ,  Walker, Edna S. ,  Smith, Jane B. ,  Tayi, Apparao ,  Vaught, James A. ,  Yost, David A. ,  Rumbaugh, William ,  Winter, Gary E. ,  Hance, Robert B. ,  Stanton, Alyn K. ,  Oleksak, Carl M. ,  Watkins, William E. III. ,  Vickstrom, Richard L. ,  Cloonan, Kevin M. ,  Wohlford Robert A. ,  Hills, David B. Jr. ,  Schrier, Paul R.

IPC: G01N35/02 ,  G01N35/10 ,  F04B53/00

CPC classification number: G01N21/0303 ,  B01L3/08 ,  B01L3/5025 ,  B01L3/5085 ,  B01L3/50853 ,  B01L9/06 ,  B01L2200/142 ,  B01L2200/16 ,  B01L2300/042 ,  B01L2300/043 ,  G01N21/253 ,  G01N33/5302 ,  G01N33/537 ,  G01N33/538 ,  G01N33/542 ,  G01N33/54313 ,  G01N35/0092 ,  G01N35/0099 ,  G01N35/025 ,  G01N35/026 ,  G01N35/1004 ,  G01N2001/007 ,  G01N2035/00287 ,  G01N2035/00356 ,  G01N2035/00386 ,  G01N2035/00455 ,  G01N2035/00475 ,  G01N2035/00495 ,  G01N2035/00524 ,  G01N2035/00752 ,  G01N2035/0093 ,  G01N2035/0405 ,  G01N2035/0436 ,  G01N2035/0441 ,  G01N2035/0443 ,  G01N2035/0444 ,  G01N2035/0448 ,  G01N2035/0453 ,  G01N2035/0465 ,  G01N2035/1025 ,  G01N2035/1076 ,  G01N2035/1086 ,  H01J49/04

Abstract: A bubble flushing aspirating and dispensing syringe having precision and volumetric accuracy, particularly for use in an automated, continuous and random access analytical system, is disclosed. The syringe comprises a piston (124) within a bore (128), the bore having seal means at a first end and a closed end (130) at a second end, wherein the piston forms an annulus (138) with the bore wall and seal means, and is capable of reciprocating therein. Fluid inlet (134) and fluid outlet (136) means are in communication with the annulus (138) and bore, the fluid inlet and fluid outlet means being located between the seal means and the bore closed end. A fluid source is in communication with the inlet means and a fluid conduit is in communication with the outlet means and an open-ended release tip. A drive means is connected to the piston for reciprocating the piston within the bore. As a result, fluid from the inlet, when connected to a fluid supply, flows through the annulus (138) around the sides of the piston and out through the fluid outlet to the open-ended tip, thereby creating a cross-flow pattern in the annulus (138) around the piston as it reciprocates in the bore to flush bubbles through the outlet.

Abstract translation: 公开了一种具有精确度和体积精确度的泡冲洗抽吸和分配注射器，特别用于自动化，连续和随机进入分析系统。 所述注射器包括在孔（128）内的活塞（124），所述孔在第一端具有密封装置而在第二端具有封闭端（130），其中所述活塞与所述孔壁形成环带（138），以及 密封装置，并且能够在其中往复运动。 流体入口（134）和流体出口（136）装置与环形空间（138）和孔连通，流体入口和流体出口装置位于密封装置和孔封闭端之间。 流体源与入口装置连通并且流体导管与出口装置和开放式释放末端连通。 驱动装置连接到活塞，用于使活塞在孔内往复运动。 结果，来自入口的流体在连接到流体供应源时流过环绕活塞侧面的环形空间（138）并且通过流体出口流出到开放式末端，由此在流体出口处形成交叉流动模式 当活塞在孔内往复运动时围绕活塞的环形空间（138）以通过出口冲洗气泡。

公开(公告)号：EP1443329A2

公开(公告)日：2004-08-04

申请号：EP04010960.5

申请日：1994-09-22

Applicant: Abbott Laboratories

Inventor： Clark, Frederick L. ,  Clemens, John M. ,  Hance, Robert B. ,  Hendrick, Kendall B. ,  Tayi, Apparao ,  Kanewske, William J. III ,  Lagocki, Peter A. ,  Martin, Richard R. ,  McDowell, Douglas D. ,  Merriam, Richard A. ,  Moore, Larry W. ,  Oleksak, Carl M. ,  Pennington, Charles D. ,  Raymoure, William J. ,  Rumbaugh, William D. ,  Schmidt, Linda S. ,  Schrier, Paul R. ,  Smith, Jane B. ,  Spronk, Adrian M. ,  Walker, Edna S. ,  Vaught, James A. ,  Vickstrom, Richard L. ,  Walker, Donny Ray ,  Watkins, William E. III ,  Winter, Gary E. ,  Wohlford, Robert A. ,  Clift, Gilbert ,  Cloonan, Kevin M. ,  Mitchell, James E. ,  Stanton, Alyn K. ,  Yost, David A. ,  Hills, David B.

IPC: G01N35/02 ,  G01N33/53

CPC classification number: G01N35/0092 ,  B01F11/0022 ,  B01L3/5025 ,  B29C45/00 ,  G01N21/6445 ,  G01N21/6452 ,  G01N21/76 ,  G01N33/5302 ,  G01N33/542 ,  G01N33/54313 ,  G01N35/0099 ,  G01N35/025 ,  G01N35/1004 ,  G01N35/1065 ,  G01N2001/007 ,  G01N2021/6482 ,  G01N2035/00148 ,  G01N2035/00356 ,  G01N2035/0405 ,  G01N2035/0441 ,  G01N2035/0443 ,  G01N2035/0444 ,  G01N2035/0446 ,  G01N2035/1025 ,  G01N2035/1076 ,  G01N2035/1086 ,  H01J49/04

Abstract: The present invention relates to a method for simultaneously performing at least two assays, said assays comprising a plurality of activities, for a plurality of liquid samples on a continuous analytical system, said method comprising the steps of: combining an aliquot of a first liquid sample with at least one reagent in a first reaction container to form a first assay reaction mixture for said first liquid sample; combining an aliquot of a second liquid sample with at least one reagent in a second reaction container to form a second assay reaction mixture for said second liquid sample; incubating said first and said second assay reaction mixtures at least one time; performing activities associated with each assay other than said combining and said incubating on the first and second assay reaction mixtures to complete each assay, said other activities including analyzing the incubated assay reaction mixtures; and scheduling the steps of said combining, said incubating, and said performing activities other than said combining and said incubating associated with each of the assays according to a predetermined protocol, said protocol specifying: (a) what activities are to be performed for a given assay; (b) an order in which said activities of (a) are to be performed; (c) at least one incubation period between said activities of (a), said at least one incubation period comprising a nominal period of time for the performance of an incubating step between activities of (a) and a specified window of time for varying the duration of the nominal period between activities of (a) to optimize performance; (d) how said activities of (a) are to be performed; and (e) duration of said activities of (a).

Abstract translation: 本发明涉及一种用于同时进行至少两种测定的方法，所述测定法包括多个活性，对于连续分析系统上的多个液体样品，所述方法包括以下步骤：将等分试样的第一液体样品 与第一反应容器中的至少一种试剂形成用于所述第一液体样品的第一测定反应混合物; 将第二液体样品的等分试样与第二反应容器中的至少一种试剂组合以形成用于所述第二液体样品的第二测定反应混合物; 至少一次孵育所述第一和所述第二测定反应混合物; 执行与所述组合以外的每个测定相关的活动，并且在第一和第二测定反应混合物上孵育以完成每个测定，所述其它活性包括分析培养的测定反应混合物; 并且根据预定协议安排所述组合，所述孵育和所述执行活动之外的所述组合和所述孵化与每个测定相关联的步骤，所述协议规定：（a）将对给定的 法; （b）执行（a）的活动的命令; （c）所述活动之间的至少一个潜伏期（a），所述至少一个潜伏期包括在（a）的活动与指定的时间窗口之间执行孵化步骤的标称时间段，以改变 活动之间的名义期间的持续时间（a）优化业绩; （d）如何执行（a）的活动; （e）（a）所述活动的持续时间。

公开(公告)号：EP1205756A2

公开(公告)日：2002-05-15

申请号：EP02001046.8

申请日：1994-09-22

Applicant: Abbott Laboratories

Inventor： Clark, Frederick L. ,  Clemens, John M. ,  Hance, Robert B. ,  Hendrick, Kendall B. ,  Tayi, Apparao ,  Kanewske, William J., III ,  Lagocki, Peter A. ,  Martin, Richard R. ,  McDowell, Douglas D. ,  Merriam, Richard A. ,  Moore, Larry W. ,  Oleksak, Carl M. ,  Pennington, Charles D. ,  Raymoure, William J. ,  Rumbaugh, William D. ,  Schmidt, Linda S. ,  Schrier, Paul R. ,  Smith, Jane B. ,  Spronk, Adrian M. ,  Walker, Edna S. ,  Vaught, James A. ,  Vickstrom, Richard L. ,  Walker, Donny Ray ,  Watkins, William E., III ,  Winter, Gary E. ,  Wohlford, Robert A. ,  Clift, Gilbert ,  Cloonan, Kevin M. ,  Mitchell, James E. ,  Stanton, Alyn K. ,  Yost, David A. ,  Hills, David B.

IPC: G01N35/10

CPC classification number: G01N35/0092 ,  B01F11/0022 ,  B01L3/5025 ,  B29C45/00 ,  G01N21/6445 ,  G01N21/6452 ,  G01N21/76 ,  G01N33/5302 ,  G01N33/542 ,  G01N33/54313 ,  G01N35/0099 ,  G01N35/025 ,  G01N35/1004 ,  G01N35/1065 ,  G01N2001/007 ,  G01N2021/6482 ,  G01N2035/00148 ,  G01N2035/00356 ,  G01N2035/0405 ,  G01N2035/0441 ,  G01N2035/0443 ,  G01N2035/0444 ,  G01N2035/0446 ,  G01N2035/1025 ,  G01N2035/1076 ,  G01N2035/1086 ,  H01J49/04

Abstract: The invention relates to an automated liquid level sensing system for detecting the presence of liquid in a container, said liquid level sensing system comprising: a vertically oriented, electrically conductive probe positioned above said container; means for vertically moving said probe into and out of said container; a signal source electrically connected to said probe, said signal source energizing said probe with an electrical signal and causing said probe to transmit said electrical signal; a receiving antenna positioned below said container for receiving said transmitted electrical signal; means for analyzing said received electrical signal for indications that said probe has contacted liquid in said container; means for transferring said received electrical signal from said receiving antenna to said analyzing means; and means for indicating that liquid has been detected. Further, the invention also provides for a method for automatically detecting the presence of liquid in a container, said method comprising the steps of: vertically positioning an electrically conductive probe above said container; vertically moving said probe into and out of said container; electrically connecting a signal source to said probe, said signal source energizing said probe with an electrical signal and causing said probe to transmit said electrical signal; positioning a receiving antenna below said container for receiving said transmitted electrical signal; analyzing said received electrical signal for indications that said probe has contacted liquid in said container; transferring said received electrical signal from said receiving antenna to said analyzing means; and indicating that liquid has been detected.

Abstract translation: 本发明涉及一种用于检测容器中液体存在的自动液位传感系统，所述液位传感系统包括：位于所述容器上方的垂直取向的导电探头; 垂直移动所述探针进出所述容器的装置; 信号源，其电连接到所述探针，所述信号源用电信号激励所述探针并且使所述探针传送所述电信号; 位于所述容器下方的接收天线，用于接收所述发射的电信号; 用于分析所述接收到的电信号以用于指示所述探针已经接触所述容器中的液体的装置; 用于将所述接收的电信号从所述接收天线传送到所述分析装置的装置; 以及用于指示已检测到液体的装置。 此外，本发明还提供了一种用于自动检测容器中液体存在的方法，所述方法包括以下步骤：在所述容器上方垂直放置导电探针; 垂直移动所述探针进出所述容器; 将信号源电连接到所述探头，所述信号源用电信号激励所述探头并使所述探头传送所述电信号; 将接收天线定位在所述容器下方用于接收所述传输的电信号; 分析所述接收的电信号以指示所述探针已接触所述容器中的液体; 将所述接收的电信号从所述接收天线传送到所述分析装置; 并指示已检测到液体。

公开(公告)号：EP1205756B1

公开(公告)日：2006-04-12

申请号：EP02001046.8

申请日：1994-09-22

Applicant: ABBOTT LABORATORIES

Inventor： Clark, Frederick L. ,  Clemens, John M. ,  Hance, Robert B. ,  Hendrick, Kendall B. ,  Tayi, Apparao ,  Kanewske, William J., III ,  Lagocki, Peter A. ,  Martin, Richard R. ,  McDowell, Douglas D. ,  Merriam, Richard A. ,  Moore, Larry W. ,  Oleksak, Carl M. ,  Pennington, Charles D. ,  Raymoure, William J. ,  Rumbaugh, William D. ,  Schmidt, Linda S. ,  Schrier, Paul R. ,  Smith, Jane B. ,  Spronk, Adrian M. ,  Walker, Edna S. ,  Vaught, James A. ,  Vickstrom, Richard L. ,  Walker, Donny Ray ,  Watkins, William E., III ,  Winter, Gary E. ,  Wohlford, Robert A. ,  Clift, Gilbert ,  Cloonan, Kevin M. ,  Mitchell, James E. ,  Stanton, Alyn K. ,  Yost, David A. ,  Hills, David B.

IPC: G01N35/10 ,  G01F23/284

CPC classification number: G01N35/0092 ,  B01F11/0022 ,  B01L3/5025 ,  B29C45/00 ,  G01N21/6445 ,  G01N21/6452 ,  G01N21/76 ,  G01N33/5302 ,  G01N33/542 ,  G01N33/54313 ,  G01N35/0099 ,  G01N35/025 ,  G01N35/1004 ,  G01N35/1065 ,  G01N2001/007 ,  G01N2021/6482 ,  G01N2035/00148 ,  G01N2035/00356 ,  G01N2035/0405 ,  G01N2035/0441 ,  G01N2035/0443 ,  G01N2035/0444 ,  G01N2035/0446 ,  G01N2035/1025 ,  G01N2035/1076 ,  G01N2035/1086 ,  H01J49/04

公开(公告)号：EP1028320B1

公开(公告)日：2006-03-01

申请号：EP00108051.4

申请日：1994-09-22

Applicant: ABBOTT LABORATORIES

Inventor： Clark, Frederick L. ,  Clemens, John M. ,  Hance, Robert B. ,  Hendrick, Kendall B. ,  Tayi, Apparao ,  Kanewske, William J. III ,  Lagocki, Peter A. ,  Martin, Richard R. ,  McDowell, Douglas D. ,  Merriam, Richard A. ,  Moore, Larry W. ,  Oleksak, Carl M. ,  Pennington, Charles D. ,  Raymoure, William J. ,  Rumbaugh, William D. ,  Schmidt, Linda S. ,  Schrier, Paul R. ,  Smith B., Jane ,  Spronk, Adrian M. ,  Walker, Edna S. ,  Vaught, James A. ,  Vickstrom Richard L. ,  Walker, Donny Ray ,  Watkins, William E. III ,  Winter, Gary E. ,  Wohlford, Robert A. ,  Clift, Gilbert ,  Cloonan, Kevin M. ,  Mitchell, James E. ,  Stanton, Alyn K. ,  Yost, David A. ,  Hills, David B.

IPC: G01N35/02

CPC classification number: G01N35/0092 ,  B01F11/0022 ,  B01L3/5025 ,  B29C45/00 ,  G01N21/6445 ,  G01N21/6452 ,  G01N21/76 ,  G01N33/5302 ,  G01N33/542 ,  G01N33/54313 ,  G01N35/0099 ,  G01N35/025 ,  G01N35/1004 ,  G01N35/1065 ,  G01N2001/007 ,  G01N2021/6482 ,  G01N2035/00148 ,  G01N2035/00356 ,  G01N2035/0405 ,  G01N2035/0441 ,  G01N2035/0443 ,  G01N2035/0444 ,  G01N2035/0446 ,  G01N2035/1025 ,  G01N2035/1076 ,  G01N2035/1086 ,  H01J49/04

公开(公告)号：EP1450161A8

公开(公告)日：2004-11-10

申请号：EP04010901.9

申请日：1993-03-24

Applicant: ABBOTT LABORATORIES

Inventor： Clark, Frederic L. ,  Clift, Gilbert ,  Hendrick, Kendall B. ,  Kanewske, William J. III. ,  Lagocki, Peter A. ,  Martin, Richard R. ,  Mitchell, James E. ,  Moore, Larry W. ,  Pennington, Charles D. ,  Walker, Edna S. ,  Smith, Jane B. ,  Tayi, Apparao ,  Vaught, James A. ,  Yost, David A. ,  Winter, Gary E. ,  Hance, Robert B. ,  Stanton, Alyn K. ,  Oleksak, Carl M. ,  Watkins, William E. III. ,  Vickstrom, Richard L. ,  Cloonan, Kevin M. ,  Wohlford Robert A. ,  Hills, David B. Jr. ,  Schrier, Paul R. ,  Rumbaugh, William

IPC: G01N35/02 ,  B65B7/00

CPC classification number: G01N21/0303 ,  B01L3/08 ,  B01L3/5025 ,  B01L3/5085 ,  B01L3/50853 ,  B01L9/06 ,  B01L2200/142 ,  B01L2200/16 ,  B01L2300/042 ,  B01L2300/043 ,  G01N21/253 ,  G01N33/5302 ,  G01N33/537 ,  G01N33/538 ,  G01N33/542 ,  G01N33/54313 ,  G01N35/0092 ,  G01N35/0099 ,  G01N35/025 ,  G01N35/026 ,  G01N35/1004 ,  G01N2001/007 ,  G01N2035/00287 ,  G01N2035/00356 ,  G01N2035/00386 ,  G01N2035/00455 ,  G01N2035/00475 ,  G01N2035/00495 ,  G01N2035/00524 ,  G01N2035/00752 ,  G01N2035/0093 ,  G01N2035/0405 ,  G01N2035/0436 ,  G01N2035/0441 ,  G01N2035/0443 ,  G01N2035/0444 ,  G01N2035/0448 ,  G01N2035/0453 ,  G01N2035/0465 ,  G01N2035/1025 ,  G01N2035/1076 ,  G01N2035/1086 ,  H01J49/04

Abstract: A method for controlling evaporation and contamination of reagents used in automated diagnostic systems is disclosed as well as an apparatus for opening and closing reagent containers contained within a reagent pack having cover and cap means for such controlling of evaporation and contamination. The method comprises (a) moving reagent packs containing reagents in closed reagent containers mounted in a reagent pack carousel to an opening and closing station, (b) forcing open the evaporatively closed reagent containers contained in the reagent pack by the opening and closing station, (c) locking in an open position the reagent containers cover and cap which is affixed to the reagent containers, (d) moving the locked open reagent containers from the opening and closing station on the reagent pack carousel to a position wherein the system has access to the reagents, (e) withdrawing reagents from the reagent containers for system use, (f) returning the reagent pack and reagent containers on the reagent pack carousel to the opening and closing station, (g) unlocking the lock open cover and cap of the reagent containers, (h) force closing the cover and cap of the reagent containers of the reagent pack, and (i) removing the reagent pack from the opening and closing station.

Abstract translation: 公开了一种用于控制自动诊断系统中使用的试剂的蒸发和污染的方法以及一种用于打开和关闭容纳在试剂包内的试剂容器的设备，该试剂容器具有用于控制蒸发和污染的盖和盖装置。 该方法包括：（a）将包含试剂的试剂包在安装在试剂包转盘中的封闭的试剂容器中移动到打开和关闭站，（b）通过打开和关闭站强制打开包含在试剂包中的蒸发封闭的试剂容器， （c）将试剂容器盖和盖固定在试剂容器上的锁定打开位置，（d）将锁定的打开的试剂容器从试剂容器转盘上的打开和关闭站移动到系统可以进入的位置 （e）从用于系统使用的试剂容器中取出试剂，（f）将试剂包转盘上的试剂包和试剂容器返回到打开和关闭站，（g）解锁锁定打开盖和盖 试剂容器，（h）强制关闭试剂包的试剂容器的盖子和盖子，以及（i）从开闭站取出试剂包。

公开(公告)号：EP1450162A3

公开(公告)日：2004-09-15

申请号：EP04010903.5

申请日：1993-03-24

Applicant: ABBOTT LABORATORIES

Inventor： Clark, Frederick L. ,  Clift, Gilbert ,  Hendrick, Kendall B. ,  Kanewske, William J. III. ,  Lagocki, Peter A. ,  Martin, Richard R. ,  Mitchell, James E. ,  Moore, Larry W. ,  Pennington, Charles D. ,  Walker, Edna S. ,  Smith, Jane B. ,  Tayi, Apparao ,  Vaught, James A. ,  Yost, David A. ,  Rumbaugh, William ,  Winter, Gary E. ,  Hance, Robert B. ,  Stanton, Alyn K. ,  Oleksak, Carl M. ,  Watkins, William E. III. ,  Vickstrom, Richard L. ,  Cloonan, Kevin M. ,  Wohlford Robert A. ,  Hills, David B. Jr. ,  Schrier, Paul R.

IPC: G01N35/04 ,  B65G47/14 ,  B65G47/256

CPC classification number: G01N21/0303 ,  B01L3/08 ,  B01L3/5025 ,  B01L3/5085 ,  B01L3/50853 ,  B01L9/06 ,  B01L2200/142 ,  B01L2200/16 ,  B01L2300/042 ,  B01L2300/043 ,  G01N21/253 ,  G01N33/5302 ,  G01N33/537 ,  G01N33/538 ,  G01N33/542 ,  G01N33/54313 ,  G01N35/0092 ,  G01N35/0099 ,  G01N35/025 ,  G01N35/026 ,  G01N35/1004 ,  G01N2001/007 ,  G01N2035/00287 ,  G01N2035/00356 ,  G01N2035/00386 ,  G01N2035/00455 ,  G01N2035/00475 ,  G01N2035/00495 ,  G01N2035/00524 ,  G01N2035/00752 ,  G01N2035/0093 ,  G01N2035/0405 ,  G01N2035/0436 ,  G01N2035/0441 ,  G01N2035/0443 ,  G01N2035/0444 ,  G01N2035/0448 ,  G01N2035/0453 ,  G01N2035/0465 ,  G01N2035/1025 ,  G01N2035/1076 ,  G01N2035/1086 ,  H01J49/04

Abstract: A cartridge feeder apparatus for automated diagnostic systems is disclosed. The apparatus comprises a cartridge hopper means for receiving, storing and feeding cartridges (68) to a cartridge orientation mechanism, the cartridge orientation mechanism comprised of two opposed engageable orientation means (239) for engaging and disengaging a cartridge at each end of the cartridge. The cartridge has a funnel opening at a first end and a generally flat bottom at a second end.

Abstract translation: 公开了一种用于自动诊断系统的盒式供料器设备。 该装置包括一个用于容纳，存储盒子并将盒子（68）供给盒子定位机构的盒子盒装置，盒子定位机构包括两个相对的可啮合定向装置（239），用于啮合和脱离盒子两端的盒子。 盒在第一端具有漏斗开口，在第二端具有通常平坦的底部。