公开(公告)号：CA2290505A1

公开(公告)日：1998-11-19

申请号：CA2290505

申请日：1998-05-14

Applicant: AURORA BIOSCIENCES CORP

Inventor： SHUMATE CHRISTOPHER BENTLEY ,  STYLLI CHARI ,  COASSIN PETER J ,  BECKEY SAMUEL S

IPC: G01N21/64 ,  A61K45/00 ,  B01J19/00 ,  B01L3/02 ,  B01L9/00 ,  C12M1/00 ,  C40B60/14 ,  G01N35/00 ,  G01N35/02 ,  G01N35/04 ,  G01N35/10 ,  G01N37/00 ,  G06F17/00

Abstract: The present invention provides for systems and methods that utilize automated and integratable workstations for identifying chemicals having useful activity. The present invention is also directed to chemical entities and information (e.g., chemical or biological activities of chemicals) generated or discovered by operation of workstations of the present invention. The present invention includes automated workstations that are programmably controlled to minimize processing times at each workstation and that can be integrated to minimize the processing time of the liquid samples from the start to finish of the process.

公开(公告)号：CA2262739C

公开(公告)日：2003-11-04

申请号：CA2262739

申请日：1998-05-29

Applicant: AURORA BIOSCIENCES CORP

Inventor： PHAM ANDREW A ,  HAROOTUNIAN ALEC TATE ,  COASSIN PETER J ,  MENDLEIN JOHN D ,  TSIEN ROGER Y

IPC: G01N21/64 ,  B01L3/00 ,  B01L9/00 ,  C08G61/08 ,  C40B60/14 ,  G01N21/03 ,  G01N33/483 ,  G01N33/52

Abstract: The invention provides for multi-well plates and platforms that comprise a layer of having low fluorescence and high transmittance. These multi-well plates and platforms are particularly well suited for fluorescent measuremen ts.

公开(公告)号：CA2290505C

公开(公告)日：2007-07-24

申请号：CA2290505

申请日：1998-05-14

Applicant: AURORA BIOSCIENCES CORP

Inventor： COASSIN PETER J ,  STYLLI CHARI ,  BECKEY SAMUEL S ,  SHUMATE CHRISTOPHER BENTLEY

IPC: G01N21/64 ,  G01N35/00 ,  A61K45/00 ,  B01J19/00 ,  B01L3/02 ,  B01L9/00 ,  C12M1/00 ,  C40B60/14 ,  G01N35/02 ,  G01N35/04 ,  G01N35/10 ,  G01N37/00 ,  G06F17/00

Abstract: The present invention provides for systems and methods that utilize automate d and integratable workstations for identifying chemicals having useful activity. The present invention is also directed to chemical entities and information (e.g., chemical or biological activities of chemicals) generated or discovered by operation of workstations of the present invention. The present invention includes automated workstations that are programmably controlled to minimize processing times a t each workstation and that can be integrated to minimize the processing time of the liquid samples from the start to finish of the proces s.

公开(公告)号：AU743507B2

公开(公告)日：2002-01-24

申请号：AU7478398

申请日：1998-05-14

Applicant: AURORA BIOSCIENCES CORP

Inventor： STYLLI CHARI ,  BECKEY SAMUEL S ,  SHUMATE CHRISTOPHER BENTLEY ,  COASSIN PETER J

IPC: G01N21/64 ,  A61K45/00 ,  B01J19/00 ,  B01L3/02 ,  B01L9/00 ,  C12M1/00 ,  C40B60/14 ,  G01N35/00 ,  G01N35/02 ,  G01N35/04 ,  G01N35/10 ,  G01N37/00 ,  G06F17/00

Abstract: A high throughput chemical handling system includes a chemical storage module, a transport module, and one or more liquid handling modules. The transport module may implement parallel chemical transport, and the system may include a plurality of asynchronously operable liquid handling modules coupled to the parallel transport module.

公开(公告)号：CA2289174A1

公开(公告)日：2000-05-09

申请号：CA2289174

申请日：1999-11-09

Applicant: AURORA BIOSCIENCES CORP

Inventor： SASAKI GLENN ,  COASSIN PETER J ,  MERE LORA ,  CUBITT ANDREW B ,  PHAM ANDREW A ,  HAROOTUNIAN ALEC

IPC: B01L3/00 ,  G01N35/00 ,  G01N33/50 ,  C12Q1/00 ,  G01N1/00 ,  G01N21/59 ,  G01N21/63 ,  G01N31/22

Abstract: The present invention provides liquid barriers that can reduce the evaporation of a liquid sample and incompatible with living cells. The liquid barriers of the present invention replace the need for mechanical barriers, such as lids and covers, for use with assay containers, such as multi-well platforms. The use of such liquid barriers rather than mechanical barriers reduces the need for robotics in automated screening procedures and thus allows for higher throughput in such procedures.

公开(公告)号：AU7709198A

公开(公告)日：1998-12-21

申请号：AU7709198

申请日：1998-05-29

Applicant: AURORA BIOSCIENCES CORP

Inventor： PHAM ANDREW A ,  COASSIN PETER J ,  HAROOTUNIAN ALEC TATE ,  MENDLEIN JOHN D ,  TSIEN ROGER Y

IPC: G01N21/64 ,  B01L3/00 ,  B01L9/00 ,  C08G61/08 ,  C40B60/14 ,  G01N21/03 ,  G01N33/483 ,  G01N33/52

Abstract: The invention provides for multi-well plates and platforms that comprise a layer of having low fluorescence and high transmittance. These multi-well plates and platforms are particularly well suited for fluorescent measurements.

公开(公告)号：CA2262739A1

公开(公告)日：1998-12-10

申请号：CA2262739

申请日：1998-05-29

Applicant: AURORA BIOSCIENCES CORP

Inventor： TSIEN ROGER Y ,  MENDLEIN JOHN D ,  PHAM ANDREW A ,  HAROOTUNIAN ALEC TATE ,  COASSIN PETER J

IPC: G01N21/64 ,  B01L3/00 ,  B01L9/00 ,  C08G61/08 ,  C40B60/14 ,  G01N21/03 ,  G01N33/483 ,  G01N33/52

Abstract: The invention provides for multi-well plates and platforms that comprise a layer of having low fluorescence and high transmittance. These multi-well plates and platforms are particularly well suited for fluorescent measurements.