19.
    发明专利
    未知

    公开(公告)号:DE3002543A1

    公开(公告)日:1981-07-30

    申请号:DE3002543

    申请日:1980-01-25

    Applicant: BASF AG

    Abstract: 4-Tert.-butoxyphenylglycinonitrile (I) I and a process for the preparation of D-(-)-4-hydroxyphenylglycine (IIa) and L-(+)-4-hydroxyphenylglycine (IIb) wherein compound I is reacted in a conventional manner, in alcoholic solution and in the presence of a carbonyl compound, with about the equimolar amount of L-(+)-tartaric acid or D-(-)-tartaric acid and the D-(-)-I-L-(+)-tartrate or L-(+)-I-D-(-)-tartrate thereby obtained in crystalline form is converted to IIa or IIb respectively in aqueous acid solution at 20 DEG -110 DEG C. by splitting off the L-(+)-tartaric acid or D-(-)-tartaric acid, hydrolyzing the nitrile group and hydrolytically splitting off the tert.-butyl group.

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