公开(公告)号：CA1102324A

公开(公告)日：1981-06-02

申请号：CA306732

申请日：1978-07-04

Applicant: BASF AG

Inventor： GUTSCHE KLAUS ,  SCHARWAECHTER PETER ,  KOHLMANN WILHELM ,  KROEMER GERHARD

IPC: A61K31/505 ,  A61K31/535 ,  A61P31/04 ,  A61P33/02 ,  C07D239/48 ,  C07D239/49 ,  C07D403/12 ,  C07D413/12

Abstract: of the disclosure: 5-Benzyl-2,4-diaminopyrimi-dines, in which the 2-amino group is substituted, and which may or may not be substituted in the phenyl ring, and their physiologically acceptable addition salts with acids, processes for their manufacture, drugs containing these compounds, and the use of the said compounds in infectious diseases.

公开(公告)号：CA1098820A

公开(公告)日：1981-04-07

申请号：CA308681

申请日：1978-08-03

Applicant: BASF AG

Inventor： POMMER ERNST-HEINRICH ,  SCHARWAECHTER PETER ,  GUTSCHE KLAUS ,  HARTLEBEN YORK

IPC: A01N43/50 ,  C07D233/60 ,  C07D521/00 ,  A01N9/22

Abstract: The present invention relates to a process for combatting fungi on plants, wherein the plants or their loci are treated with a fungicidally effective amount of a .beta.-imidazolyl alcohol of the formula where R1 denotes fluorine, chlorine, bromine, iodine or methoxy and R2, R3 and R4 denote hydrogen, fluorine, chlorine or bromine, or a salt thereof.

公开(公告)号：CA978944A

公开(公告)日：1975-12-02

申请号：CA187357

申请日：1973-12-04

Applicant: BASF AG

Inventor： PETERSEN HARRO ,  SCHARWAECHTER PETER

IPC: C07F9/38 ,  A01N57/18 ,  A01N57/36 ,  C07F9/40 ,  C07F9/6512 ,  C07F9/653 ,  C07F9/6533 ,  C07F9/6571 ,  C07F9/6574 ,  C08K5/5353 ,  D06M13/288

公开(公告)号：AU544076B2

公开(公告)日：1985-05-16

申请号：AU6835581

申请日：1981-03-13

Applicant: BASF AG

Inventor： SCHARWAECHTER PETER ,  GUTSCHE KLAUS ,  HEBERLE WOLFGANG ,  WESENBERG WALTER ,  KOHLMANN FRIEDRICH-WILHELM

IPC: A61K31/41 ,  A61K31/4196 ,  A61P17/00 ,  A61P31/04 ,  A61P31/10 ,  C07D249/08 ,  C07D521/00

公开(公告)号：NO147483C

公开(公告)日：1983-04-20

申请号：NO780743

申请日：1978-03-03

Applicant: BASF AG

Inventor： SCHARWAECHTER PETER ,  GUTSCHE KLAUS ,  KOHLMANN FRIEDRICH-WILHELM

IPC: A61K31/505 ,  A61P31/04 ,  C07D239/48 ,  C07D239/49

Abstract: 2-Acylamino-4-amino-5-benzylpyrimidines substituted in the phenyl ring of the benzyl radical, their production and their use as sulfonamide potentiators, as well as agents containing the same, are disclosed. The compounds 4-amino-2-formamido-5-(3,4,5-trimethoxybenzyl)-pyrimidine and 4-amino-2-acetamido-5-(3,4,5-trimethoxybenzyl)-pyrimidine are examples of the subject pyrimidines.

公开(公告)号：NO814138L

公开(公告)日：1982-06-07

申请号：NO814138

申请日：1981-12-03

Applicant: BASF AG

Inventor： SCHARWAECHTER PETER ,  GUTSCHE KLAUS ,  KOHLMANN FRIEDRICH-WILHELM ,  BECK HINRICH

IPC: A61K31/505 ,  A61K31/63 ,  A61K31/635 ,  A61P31/04 ,  C07D239/48 ,  C07D239/49 ,  C07D

Abstract: 2-Carbamic acid esters of 2,4-diamino-5-(3',4',5'-trimethoxybenzyl)-pyrimidine (trimethoprim), a process for their preparation, and drugs containing these compounds, which, as pro-drugs of trimethoprim, have valuable antibacterial properties and potentiate the antibacterial action of sulfonamides.

公开(公告)号：FI813845L

公开(公告)日：1982-06-05

申请号：FI813845

申请日：1981-12-01

Applicant: BASF AG

Inventor： SCHARWAECHTER PETER ,  GUTSCHE KLAUS ,  KOHLMANN FRIEDRICH-WILHELM ,  BECK HINDRICK

IPC: A61K31/505 ,  A61K31/63 ,  A61K31/635 ,  A61P31/04 ,  C07D239/48 ,  C07D239/49 ,  C07D

Abstract: 2-Carbamic acid esters of 2,4-diamino-5-(3',4',5'-trimethoxybenzyl)-pyrimidine (trimethoprim), a process for their preparation, and drugs containing these compounds, which, as pro-drugs of trimethoprim, have valuable antibacterial properties and potentiate the antibacterial action of sulfonamides.

公开(公告)号：NO810878L

公开(公告)日：1981-09-16

申请号：NO810878

申请日：1981-03-13

Applicant: BASF AG

Inventor： SCHARWAECHTER PETER ,  GUTSCHE KLAUS ,  HEBERLE WOLFGANG ,  WESENBERG WALTER ,  KOHLMANN FRIEDRICH-WILHELM

IPC: A61K31/41 ,  A61K31/4196 ,  A61P17/00 ,  A61P31/04 ,  A61P31/10 ,  C07D249/08 ,  C07D521/00 ,  C07D

公开(公告)号：AU3790378A

公开(公告)日：1980-01-17

申请号：AU3790378

申请日：1978-07-10

Applicant: BASF AG

Inventor： SCHARWAECHTER PETER ,  GUTSCHE KLAUS ,  KOHLMANN WILHELM

IPC: A61K31/505 ,  C07D239/48 ,  C07D239/49 ,  C07D401/12 ,  C07D403/12 ,  C07D405/12 ,  C07D413/12 ,  A61K31/535 ,  A61K31/55

公开(公告)号：AU3764378A

公开(公告)日：1980-01-03

申请号：AU3764378

申请日：1978-06-30

Applicant: BASF AG

Inventor： SCHARWAECHTER PETER ,  GUTSCHE KLAUS ,  KOHLMANN WILHELM ,  KROEMER GERD

IPC: A61K31/505 ,  A61P31/04 ,  A61P33/02 ,  C07D239/48 ,  C07D239/49 ,  A61K31/63 ,  A61K31/635

Abstract: Unsubstituted or substituted 5-phenyl- and 5-benzyl-4-amino-pyrimidine-2-imidoacid esters, their preparation, drugs containing these compounds, and their use in infectious diseases.