公开(公告)号：BG101407A

公开(公告)日：1997-09-30

申请号：BG10140797

申请日：1997-04-11

Applicant: BASF AG

Inventor： LUBISCH WILFRIED ,  VIERLING MICHAEL ,  BEHL BERTHOLD ,  HOFMANN HANS P

IPC: A61K31/495 ,  A61P25/00 ,  A61P43/00 ,  C07D403/04

Abstract: Pyrrolyl-tetrahydrobenzoquinoxaline diodes having the formula are disclosed, as well as their tautomeric and isomeric forms, their physiologically compatible salts and their preparation. In the formula, the variables have the meanings given in the description. These new compounds are glutamate antagonists useful in the therapy of neurodegenerative diseases.

公开(公告)号：NO971674A

公开(公告)日：1997-06-11

申请号：NO971674

申请日：1997-04-11

Applicant: BASF AG

Inventor： LUBISCH WILFRIED ,  VIERLING MICHAEL ,  BEHL BERTHOLD ,  HOFMANN HANS PETER

IPC: A61K31/495 ,  A61P25/00 ,  A61P43/00 ,  C07D403/04

CPC classification number: C07D403/04

公开(公告)号：FI971528A0

公开(公告)日：1997-04-11

申请号：FI971528

申请日：1997-04-11

Applicant: BASF AG

Inventor： LUBISCH WILFRIED ,  VIERLING MICHAEL ,  BEHL BERTHOLD ,  HOFMANN HANS PETER

IPC: A61K31/495 ,  A61P25/00 ,  A61P43/00 ,  C07D403/04 ,  C07D

Abstract: PCT No. PCT/EP95/03902 Sec. 371 Date Mar. 27, 1997 Sec. 102(e) Date Mar. 27, 1997 PCT Filed Oct. 2, 1995 PCT Pub. No. WO90/11922 PCT Pub. Date Apr. 25, 1996Pyrrolyltetrahydrobenzoquinoxalinediones of the formula I I and their tautomeric and isomeric forms, and their physiologically tolerated salts, in which the variables have the meanings stated in the description, and the preparation thereof are described. The novel compounds are antagonists of the glutamate receptor subtypes and are thus suitable for controlling various diseases.

公开(公告)号：DK0785932T3

公开(公告)日：2000-05-01

申请号：DK95935894

申请日：1995-10-02

Applicant: BASF AG

Inventor： HOFMANN HANS PETER ,  BEHL BERTHOLD ,  LUBISCH WILFRIED ,  VIERLING MICHAEL

IPC: A61K31/495 ,  A61P25/00 ,  A61P43/00 ,  C07D403/04

Abstract: PCT No. PCT/EP95/03902 Sec. 371 Date Mar. 27, 1997 Sec. 102(e) Date Mar. 27, 1997 PCT Filed Oct. 2, 1995 PCT Pub. No. WO90/11922 PCT Pub. Date Apr. 25, 1996Pyrrolyltetrahydrobenzoquinoxalinediones of the formula I I and their tautomeric and isomeric forms, and their physiologically tolerated salts, in which the variables have the meanings stated in the description, and the preparation thereof are described. The novel compounds are antagonists of the glutamate receptor subtypes and are thus suitable for controlling various diseases.

公开(公告)号：CZ9701131A3

公开(公告)日：1998-03-18

申请号：CZ113197

申请日：1995-10-02

Applicant: BASF AG

Inventor： LUBISCH WILFRIED DR ,  VIERLING MICHAEL ,  BEHL BERTHOLD DR ,  HOFMANN HANS PETER DR

IPC: A61K31/495 ,  A61P25/00 ,  A61P43/00 ,  C07D403/04

CPC classification number: C07D403/04

公开(公告)号：PL319660A1

公开(公告)日：1997-08-18

申请号：PL31966095

申请日：1995-10-02

Applicant: BASF AG

Inventor： LUBISCH WILFRIED ,  VIERLING MICHAEL ,  BEHL BERTHOLD ,  HOFMANN HANS PETER

IPC: A61K31/495 ,  A61P25/00 ,  A61P43/00 ,  C07D403/04

Abstract: PCT No. PCT/EP95/03902 Sec. 371 Date Mar. 27, 1997 Sec. 102(e) Date Mar. 27, 1997 PCT Filed Oct. 2, 1995 PCT Pub. No. WO90/11922 PCT Pub. Date Apr. 25, 1996Pyrrolyltetrahydrobenzoquinoxalinediones of the formula I I and their tautomeric and isomeric forms, and their physiologically tolerated salts, in which the variables have the meanings stated in the description, and the preparation thereof are described. The novel compounds are antagonists of the glutamate receptor subtypes and are thus suitable for controlling various diseases.

公开(公告)号：ZA9508643B

公开(公告)日：1997-04-14

申请号：ZA9508643

申请日：1995-10-13

Applicant: BASF AG

Inventor： LUBISCH WILFRIED ,  VIERLING MICHAEL ,  BEHL BERTHOLD ,  HOFMANN HANS PETER

IPC: A61K31/495 ,  A61P25/00 ,  A61P43/00 ,  C07D403/04 ,  C07D ,  A61K

CPC classification number: C07D403/04

公开(公告)号：AU3803495A

公开(公告)日：1996-05-06

申请号：AU3803495

申请日：1995-10-02

Applicant: BASF AG

Inventor： LUBISCH WILFRIED ,  VIERLING MICHAEL ,  BEHL BERTHOLD ,  HOFMANN HANS PETER

IPC: A61K31/495 ,  A61P25/00 ,  A61P43/00 ,  C07D403/04

Abstract: PCT No. PCT/EP95/03902 Sec. 371 Date Mar. 27, 1997 Sec. 102(e) Date Mar. 27, 1997 PCT Filed Oct. 2, 1995 PCT Pub. No. WO90/11922 PCT Pub. Date Apr. 25, 1996Pyrrolyltetrahydrobenzoquinoxalinediones of the formula I I and their tautomeric and isomeric forms, and their physiologically tolerated salts, in which the variables have the meanings stated in the description, and the preparation thereof are described. The novel compounds are antagonists of the glutamate receptor subtypes and are thus suitable for controlling various diseases.

公开(公告)号：DE4436852A1

公开(公告)日：1996-04-18

申请号：DE4436852

申请日：1994-10-14

Applicant: BASF AG

Inventor： LUBISCH WILFRIED DR ,  VIERLING MICHAEL ,  BEHL BERTHOLD DR ,  HOFMANN HANS-PETER DR

IPC: A61K31/495 ,  A61P25/00 ,  A61P43/00 ,  C07D403/04 ,  C07D403/14

Abstract: Pyrrolyl-tetrahydrobenzoquinoxaline diones having the formula (I) are disclosed, as well as their tautomeric and isomeric forms, their physiologically compatible salts and their preparation. In the formula, the variables have the meanings given in the description. These new compounds are glutamate antagonists useful in the therapy of neurodegenerative diseases.