公开(公告)号：CZ113197A3

公开(公告)日：1998-03-18

申请号：CZ113197

申请日：1995-10-02

Applicant: BASF AG

Inventor： LUBISCH WILFRIED DR ,  VIERLING MICHAEL ,  BEHL BERTHOLD DR ,  HOFMANN HANS PETER DR

IPC: A61K31/495 ,  A61P25/00 ,  A61P43/00 ,  C07D403/04

Abstract: PCT No. PCT/EP95/03902 Sec. 371 Date Mar. 27, 1997 Sec. 102(e) Date Mar. 27, 1997 PCT Filed Oct. 2, 1995 PCT Pub. No. WO90/11922 PCT Pub. Date Apr. 25, 1996Pyrrolyltetrahydrobenzoquinoxalinediones of the formula I I and their tautomeric and isomeric forms, and their physiologically tolerated salts, in which the variables have the meanings stated in the description, and the preparation thereof are described. The novel compounds are antagonists of the glutamate receptor subtypes and are thus suitable for controlling various diseases.

公开(公告)号：NO971674D0

公开(公告)日：1997-04-11

申请号：NO971674

申请日：1997-04-11

Applicant: BASF AG

Inventor： LUBISCH WILFRIED ,  VIERLING MICHAEL ,  BEHL BERTHOLD ,  HOFMANN HANS PETER

IPC: A61K31/495 ,  A61P25/00 ,  A61P43/00 ,  C07D403/04

Abstract: PCT No. PCT/EP95/03902 Sec. 371 Date Mar. 27, 1997 Sec. 102(e) Date Mar. 27, 1997 PCT Filed Oct. 2, 1995 PCT Pub. No. WO90/11922 PCT Pub. Date Apr. 25, 1996Pyrrolyltetrahydrobenzoquinoxalinediones of the formula I I and their tautomeric and isomeric forms, and their physiologically tolerated salts, in which the variables have the meanings stated in the description, and the preparation thereof are described. The novel compounds are antagonists of the glutamate receptor subtypes and are thus suitable for controlling various diseases.

公开(公告)号：NO971674L

公开(公告)日：1997-06-11

申请号：NO971674

申请日：1997-04-11

Applicant: BASF AG

Inventor： LUBISCH WILFRIED ,  VIERLING MICHAEL ,  BEHL BERTHOLD ,  HOFMANN HANS PETER

IPC: A61K31/495 ,  A61P25/00 ,  A61P43/00 ,  C07D403/04

Abstract: PCT No. PCT/EP95/03902 Sec. 371 Date Mar. 27, 1997 Sec. 102(e) Date Mar. 27, 1997 PCT Filed Oct. 2, 1995 PCT Pub. No. WO90/11922 PCT Pub. Date Apr. 25, 1996Pyrrolyltetrahydrobenzoquinoxalinediones of the formula I I and their tautomeric and isomeric forms, and their physiologically tolerated salts, in which the variables have the meanings stated in the description, and the preparation thereof are described. The novel compounds are antagonists of the glutamate receptor subtypes and are thus suitable for controlling various diseases.

公开(公告)号：ZA958643B

公开(公告)日：1997-04-14

申请号：ZA958643

申请日：1995-10-13

Applicant: BASF AG

Inventor： LUBISCH WILFRIED ,  VIERLING MICHAEL ,  BEHL BERTHOLD ,  HOFMANN HANS PETER

IPC: A61K31/495 ,  A61P25/00 ,  A61P43/00 ,  C07D403/04 ,  C07D ,  A61K

Abstract: PCT No. PCT/EP95/03902 Sec. 371 Date Mar. 27, 1997 Sec. 102(e) Date Mar. 27, 1997 PCT Filed Oct. 2, 1995 PCT Pub. No. WO90/11922 PCT Pub. Date Apr. 25, 1996Pyrrolyltetrahydrobenzoquinoxalinediones of the formula I I and their tautomeric and isomeric forms, and their physiologically tolerated salts, in which the variables have the meanings stated in the description, and the preparation thereof are described. The novel compounds are antagonists of the glutamate receptor subtypes and are thus suitable for controlling various diseases.

公开(公告)号：FI971528A

公开(公告)日：1997-04-11

申请号：FI971528

申请日：1997-04-11

Applicant: BASF AG

Inventor： LUBISCH WILFRIED ,  VIERLING MICHAEL ,  BEHL BERTHOLD ,  HOFMANN HANS PETER

IPC: A61K31/495 ,  A61P25/00 ,  A61P43/00 ,  C07D403/04 ,  C07D

Abstract: PCT No. PCT/EP95/03902 Sec. 371 Date Mar. 27, 1997 Sec. 102(e) Date Mar. 27, 1997 PCT Filed Oct. 2, 1995 PCT Pub. No. WO90/11922 PCT Pub. Date Apr. 25, 1996Pyrrolyltetrahydrobenzoquinoxalinediones of the formula I I and their tautomeric and isomeric forms, and their physiologically tolerated salts, in which the variables have the meanings stated in the description, and the preparation thereof are described. The novel compounds are antagonists of the glutamate receptor subtypes and are thus suitable for controlling various diseases.

公开(公告)号：AT188214T

公开(公告)日：2000-01-15

申请号：AT95935894

申请日：1995-10-02

Applicant: BASF AG

Inventor： LUBISCH WILFRIED ,  VIERLING MICHAEL ,  BEHL BERTHOLD ,  HOFMANN HANS PETER

IPC: A61K31/495 ,  A61P25/00 ,  A61P43/00 ,  C07D403/04 ,  C07D241/00 ,  C07D207/00

Abstract: PCT No. PCT/EP95/03902 Sec. 371 Date Mar. 27, 1997 Sec. 102(e) Date Mar. 27, 1997 PCT Filed Oct. 2, 1995 PCT Pub. No. WO90/11922 PCT Pub. Date Apr. 25, 1996Pyrrolyltetrahydrobenzoquinoxalinediones of the formula I I and their tautomeric and isomeric forms, and their physiologically tolerated salts, in which the variables have the meanings stated in the description, and the preparation thereof are described. The novel compounds are antagonists of the glutamate receptor subtypes and are thus suitable for controlling various diseases.

公开(公告)号：BR9509337A

公开(公告)日：1998-01-27

申请号：BR9509337

申请日：1995-10-02

Applicant: BASF AG

Inventor： LUBISCH WILFRIED ,  VIERLING MICHAEL ,  BEHL BERTHOLD ,  HOFMANN HANS PETER

IPC: A61K31/495 ,  A61P25/00 ,  A61P43/00 ,  C07D403/04

Abstract: PCT No. PCT/EP95/03902 Sec. 371 Date Mar. 27, 1997 Sec. 102(e) Date Mar. 27, 1997 PCT Filed Oct. 2, 1995 PCT Pub. No. WO90/11922 PCT Pub. Date Apr. 25, 1996Pyrrolyltetrahydrobenzoquinoxalinediones of the formula I I and their tautomeric and isomeric forms, and their physiologically tolerated salts, in which the variables have the meanings stated in the description, and the preparation thereof are described. The novel compounds are antagonists of the glutamate receptor subtypes and are thus suitable for controlling various diseases.

公开(公告)号：MX9702659A

公开(公告)日：1997-06-28

申请号：MX9702659

申请日：1995-10-02

Applicant: BASF AG

Inventor： LUBISCH WILFRIED ,  VIERLING MICHAEL ,  BEHL BERTHOLD ,  HOFMANN HANS PETER

IPC: A61K31/495 ,  A61P25/00 ,  A61P43/00 ,  C07D403/04 ,  C07D241/00 ,  C07D207/00

Abstract: Se describen pirroliltetrahidrobenzoquinoxalindionas de la formula I y sus formas tautoméricas e isoméricas, y sus sales fisiologicamente toleradas, en donde las variables tienen los significados establecidos en la descripcion, y la preparacion de las mismas. Los compuestos novedosos son adecuados para controlar enfermedades.

公开(公告)号：CA2201527A1

公开(公告)日：1996-04-25

申请号：CA2201527

申请日：1995-10-02

Applicant: BASF AG

Inventor： LUBISCH WILFRIED ,  HOFMANN HANS PETER ,  BEHL BERTHOLD ,  VIERLING MICHAEL

IPC: A61K31/495 ,  A61P25/00 ,  A61P43/00 ,  C07D403/04 ,  C07D401/14 ,  C07D403/14

Abstract: Pyrrolyl-tetrahydrobenzoquinoxaline diones having the formula (I) are disclosed, as well as their tautomeric and isomeric forms, their physiologically compatible salts and their preparation. In the formula, the variables have the meanings given in the description. These new compounds are glutamate antagonists useful in the therapy of neurodegenerative diseases.

公开(公告)号：DE59507539D1

公开(公告)日：2000-02-03

申请号：DE59507539

申请日：1995-10-02

Applicant: BASF AG

Inventor： LUBISCH WILFRIED ,  VIERLING MICHAEL ,  BEHL BERTHOLD ,  HOFMANN HANS

IPC: A61K31/495 ,  A61P25/00 ,  A61P43/00 ,  C07D403/04

Abstract: PCT No. PCT/EP95/03902 Sec. 371 Date Mar. 27, 1997 Sec. 102(e) Date Mar. 27, 1997 PCT Filed Oct. 2, 1995 PCT Pub. No. WO90/11922 PCT Pub. Date Apr. 25, 1996Pyrrolyltetrahydrobenzoquinoxalinediones of the formula I I and their tautomeric and isomeric forms, and their physiologically tolerated salts, in which the variables have the meanings stated in the description, and the preparation thereof are described. The novel compounds are antagonists of the glutamate receptor subtypes and are thus suitable for controlling various diseases.