公开(公告)号：AT240932T

公开(公告)日：2003-06-15

申请号：AT99118428

申请日：1999-09-17

Applicant: BASF AG

Inventor： STUERMER RAINER ,  KLATT MARTIN JOCHEN ,  BOERMER ARMIN ,  HOLZ JENS ,  VOSS GUDRUN

IPC: B01J31/24 ,  C07B53/00 ,  C07B61/00 ,  C07C67/297 ,  C07C67/31 ,  C07C69/67 ,  C07C69/675 ,  C07C69/732

Abstract: Enantiomerically pure beta -hydroxyesters (I) are prepared by asymmetric hydrogenation of a beta -hydroxyester (II) over a ruthenium complex catalyst (III) containing an optically active bidentate bis-phospholane ligand. Preparation of enantiomerically pure beta -hydroxyesters (I) involves reacting a beta -hydroxyester (II) with hydrogen in presence of a ruthenium complex catalyst of formula (III): LRuX2 (III) X = halo, acetate, allyl, methallyl, 2-phenylallyl, perchlorate, trifluoroacetate, tetrafluoroborate, hexafluoroantimonate, hexafluorophosphate, hexafluoroarsenate or trichloroacetate; L = bidentate bis-phospholane ligand of formula (A) : Y = bridging group providing 1-5C between the two P atoms; R1 = H, 1-6C alkyl, aryl, alkaryl or Si(R2)3; R2 = alkyl or aryl; m = 0 and R3 = OR4; or m = 1 and R3 = H; R4 = as R1.

公开(公告)号：AT228139T

公开(公告)日：2002-12-15

申请号：AT99926460

申请日：1999-05-28

Applicant: BASF AG

Inventor： STUERMER RAINER ,  BOERNER ARMIN ,  HOLZ JENS ,  VOSS GUDRUN

IPC: B01J31/24 ,  C07B53/00 ,  C07B61/00 ,  C07C45/50 ,  C07C51/36 ,  C07C55/02 ,  C07C67/303 ,  C07C69/34 ,  C07C231/12 ,  C07C233/47 ,  C07F9/6568 ,  C07F15/00 ,  C07M7/00

Abstract: Phospolanes and diphospholanes of the general formula Iwhere: is H, C 1 -C 6 -aryl, alkylaryl, SiR 3 , R is alkyl or aryl, A is H, C 1 -C 6 -alkyl, aryl, Cl orB is a linker with 1-5 C atoms between the two P atoms, and their use as catalyst in asymmetric synthesis.

公开(公告)号：DE59803583D1

公开(公告)日：2002-05-16

申请号：DE59803583

申请日：1998-05-29

Applicant: BASF AG ,  MAX PLANCK GESELLSCHAFT

Inventor： STUERMER DR ,  BOERNER DR ,  HOLZ DR ,  VOSS GUDRUN

IPC: B01J31/22 ,  B01J31/24 ,  C07B53/00 ,  C07C45/50 ,  C07F9/6568 ,  C07F15/00

Abstract: Phospholane and diphospholane compounds of formula (I) are new. R , R = independently 1-6C alkyl, aryl or alkylaryl (R may also be H); Either A has the same meanings as R , or is a group of formula (i), where B is a 1-5C bridging group. Also claimed are metal complexes of (I) whose metal atom is selected from Rh, Ru, Ir, Pd, Pt or Ni. Also claimed is a method for asymmetric hydrogenation of a starting compound, which comprises reacting it with hydrogen in the presence of the metal complex at 1 - 2 bar.

公开(公告)号：CA2333888A1

公开(公告)日：1999-12-09

申请号：CA2333888

申请日：1999-05-28

Applicant: BASF AG

Inventor： HOLZ JENS ,  STURMER RAINER ,  BORNER ARMIN ,  VOSS GUDRUN

IPC: B01J31/24 ,  C07B53/00 ,  C07B61/00 ,  C07C45/50 ,  C07C51/36 ,  C07C55/02 ,  C07C67/303 ,  C07C69/34 ,  C07C231/12 ,  C07C233/47 ,  C07F9/6568 ,  C07F15/00

Abstract: The invention relates to phospholanes and diphospholanes of general formula (I), whereby R represents H, C1-C6-alkyl, aryl, alkyl aryl, SiR23, R2 represents alkyl or aryl, A represents H, C1-C6-alkyl, aryl, Cl, or (a), and B represents a binding link with 1-5 C-atoms between both P-atoms. The inventi on also relates to the use of said phospholanes and diphospholanes as a catalys t in asymmetric synthesis.

公开(公告)号：DE19725796A1

公开(公告)日：1998-12-24

申请号：DE19725796

申请日：1997-06-18

Applicant: BASF AG ,  MAX PLANCK GESELLSCHAFT

Inventor： STUERMER RAINER DR ,  BOERNER ARMIN DR ,  HOLZ JENS DR ,  VOSS GUDRUN

IPC: B01J31/22 ,  B01J31/24 ,  C07B53/00 ,  C07C45/50 ,  C07F9/6568 ,  C07F15/00 ,  C07C233/47 ,  C07C231/12 ,  C07C69/34 ,  C07C67/303

Abstract: Phospholane and diphospholane compounds of formula (I) are new. R , R = independently 1-6C alkyl, aryl or alkylaryl (R may also be H); Either A has the same meanings as R , or is a group of formula (i), where B is a 1-5C bridging group. Also claimed are metal complexes of (I) whose metal atom is selected from Rh, Ru, Ir, Pd, Pt or Ni. Also claimed is a method for asymmetric hydrogenation of a starting compound, which comprises reacting it with hydrogen in the presence of the metal complex at 1 - 2 bar.