公开(公告)号：AU776205B2

公开(公告)日：2004-09-02

申请号：AU4758100

申请日：2000-05-19

Applicant: BASF AG

Inventor： PELZER STEFAN ,  HUBER PETRA ,  SUESSMUTH RODERICH ,  RECKTENWALD JUERGEN ,  HECKMANN DOROTHEE ,  WOHLLEBEN WOLFGANG

IPC: C12N15/09 ,  C07H17/00 ,  C12N1/15 ,  C12N1/19 ,  C12N1/21 ,  C12N5/10 ,  C12N9/14 ,  C12N15/52 ,  C12N15/55 ,  C12P21/02 ,  C07K9/00

Abstract: The invention relates to a process halogenation, which comprises halogenating a chemical compound in the presence of a halogenase, where the halogenase is(a) encoded by the sequence specified in SEQ ID NO: 1 or a sequence derived therefrom on the basis of the degeneracy of the genetic code, or is(b) encoded by a nucleic acid sequence which codes for a functional fragment of (a) or(c) by a sequence which hybridizes with (a) or (b) under standard conditions, or is(d) encoded by a sequence which has more than 30% identity or more than 60% similarity with the sequence specified under (a).

公开(公告)号：NO20020379A

公开(公告)日：2002-03-19

申请号：NO20020379

申请日：2002-01-24

Applicant: BASF AG

Inventor： HAUER BERNHARD ,  WOHLLEBEN WOLFGANG ,  SCHMID ROLF D ,  ENZELBERGER MARKUS ,  ZOCHER FRANK

IPC: C12N9/14 ,  C12N1/20 ,  C12N15/31 ,  C12P7/02 ,  C12P41/00 ,  C12Q1/02 ,  C12Q1/34 ,  C12R1/465 ,  C12N

CPC classification number: C12Q1/34 ,  C12N9/14 ,  C12P7/02 ,  C12P41/00

公开(公告)号：DE19935113A1

公开(公告)日：2001-02-01

申请号：DE19935113

申请日：1999-07-27

Applicant: BASF AG

Inventor： ZOCHER FRANK ,  ENZELBERGER MARKUS ,  SCHMID ROLF D ,  WOHLLEBEN WOLFGANG ,  HAUER BERNHARD

IPC: C12N1/20 ,  C12N9/14 ,  C12N15/31 ,  C12P7/02 ,  C12P41/00 ,  C12Q1/02 ,  C12Q1/34 ,  C12R1/465

Abstract: The invention relates to epoxide hydrolases from bacteria of the genus Streptomyces sp., to a novel method for the enzymatic separation of epoxide-enantiomer mixtures, to a novel assay method for epoxide hydrolase activity, to a screening method for detecting epoxide hydrolase activity and to the use of bacteria of the genus Streptomyces sp. and the epoxide hydrolases obtained from them for an enantio-selective epoxide hydrolysis.

公开(公告)号：CA2329992A1

公开(公告)日：1999-11-04

申请号：CA2329992

申请日：1999-04-13

Applicant: BASF AG

Inventor： WOHLLEBEN WOLFGANG ,  FISCHER PETER ,  HAUER BERNHARD ,  LUTZ-WAHL SABINE ,  SCHERR OLIVER ,  SCHMID ROLF D ,  SCHMIDT-DANNERT CLAUDIA

IPC: C07C403/16 ,  C12P1/06 ,  C12P7/02 ,  C12P7/26 ,  C12R1/465

Abstract: The invention relates to a method for oxidising substituted trimethylcyclohexenyl compounds in the presence of microorganisms of the actinomycetal order and to the use of microorganisms in oxidation reactions.

公开(公告)号：CA2380185C

公开(公告)日：2011-09-13

申请号：CA2380185

申请日：2000-07-26

Applicant: BASF AG

Inventor： ZOCHER FRANK ,  ENZELBERGER MARKUS ,  SCHMID ROLF D ,  WOHLLEBEN WOLFGANG ,  HAUER BERNHARD

IPC: C12N9/14 ,  C12N1/20 ,  C12N15/31 ,  C12P7/02 ,  C12P41/00 ,  C12Q1/02 ,  C12Q1/34 ,  C12R1/465

Abstract: The invention relates to epoxide hydrolases from bacteria of the genus Streptomyces sp., to a novel method for the enzymatic separation of epoxide-enantiomer mixtures, to a novel assay method for epoxide hydrolase activity, to a screening method for detecting epoxide hydrolase activity and to the use of bacteria of the genus Streptomyces sp. and the epoxide hydrolases obtained from them for an enantio-selective epoxide hydrolysis.

公开(公告)号：CA2380185A1

公开(公告)日：2001-02-01

申请号：CA2380185

申请日：2000-07-26

Applicant: BASF AG

Inventor： ZOCHER FRANK ,  SCHMID ROLF D ,  WOHLLEBEN WOLFGANG ,  ENZELBERGER MARKUS ,  HAUER BERNHARD

IPC: C12N1/20 ,  C12N9/14 ,  C12N15/31 ,  C12P7/02 ,  C12P41/00 ,  C12Q1/02 ,  C12Q1/34 ,  C12R1/465

Abstract: The invention relates to epoxide hydrolases from bacteria of the genus Streptomyces sp., to a novel method for the enzymatic separation of epoxide- enantiomer mixtures, to a novel assay method for epoxide hydrolase activity, to a screening method for detecting epoxide hydrolase activity and to the us e of bacteria of the genus Streptomyces sp. and the epoxide hydrolases obtaine d from them for an enantio-selective epoxide hydrolysis.

公开(公告)号：DE19926770A1

公开(公告)日：2000-12-14

申请号：DE19926770

申请日：1999-06-11

Applicant: BASF AG

Inventor： PELZER STEFAN ,  HUBER PETRA ,  SUESSMUTH RODERICH ,  RECKTENWALD JUERGEN ,  HECKMANN DOROTHE ,  WOHLLEBEN WOLFGANG

IPC: C12N15/09 ,  C07H17/00 ,  C12N1/15 ,  C12N1/19 ,  C12N1/21 ,  C12N5/10 ,  C12N9/14 ,  C12N15/52 ,  C12N15/55 ,  C12P21/02 ,  C12N15/63 ,  C07H21/00

Abstract: The invention relates to a halogenation method characterized in that a chemical compound is halogenated in the presence of halogenase and in that (a) said halogenase is coded in the sequence indicated in SEQ ID NO: 1 or in a sequence derived therefrom on the basis of a degenerate genetic code or (b) in a nucleic acid sequence which is coded for a functional fragment of (a) or (c) in a hybridizing sequence with (a) or (b) in standard conditions or (d) coded by a sequence which has an identity of more than 30 % or more than 60 % similitude with the sequence indicated in (a).

公开(公告)号：DE19818665A1

公开(公告)日：1999-10-28

申请号：DE19818665

申请日：1998-04-27

Applicant: BASF AG

Inventor： HAUER BERNHARD ,  WOHLLEBEN WOLFGANG ,  FISCHER PETER ,  LUTZ-WAHL SABINE ,  SCHMIDT-DANNERT CLAUDIA ,  SCHMID ROLF D ,  SCHERR OLIVER

IPC: C07C403/16 ,  C12P1/06 ,  C12P7/02 ,  C12P7/26 ,  C12R1/465 ,  C07C45/64 ,  C07C49/242 ,  C07C45/28 ,  C07C49/603 ,  C07C49/647 ,  C07B41/02 ,  C07B41/06

Abstract: Hydroxy and/or oxo groups are introduced into trimethyl-cyclohexene compounds (I) by selective microbiological oxidation using Actinomycetales. Oxidation of trimethyl-cyclohexene derivatives of formula (I) to hydroxy and/or oxo derivatives of formula (II) is effected in presence of bacteria of the order Actinomycetales. R1 = optionally substituted, optionally unsaturated 1-8C alkyl; R2, R3 = H, =O or OH, provided that at least one is other than H; a, b = additional bond in one of the two indicated positions. AN Independent claim is included for the use of the above bacteria for the oxidation of (I).

公开(公告)号：NO20020379L

公开(公告)日：2002-03-19

申请号：NO20020379

申请日：2002-01-24

Applicant: BASF AG

Inventor： HAUER BERNHARD ,  WOHLLEBEN WOLFGANG ,  SCHMID ROLF D ,  ENZELBERGER MARKUS ,  ZOCHER FRANK

IPC: C12N9/14 ,  C12N1/20 ,  C12N15/31 ,  C12P7/02 ,  C12P41/00 ,  C12Q1/02 ,  C12Q1/34 ,  C12R1/465 ,  C12N

公开(公告)号：AU4758100A

公开(公告)日：2001-01-02

申请号：AU4758100

申请日：2000-05-19

Applicant: BASF AG

Inventor： PELZER STEFAN ,  HUBER PETRA ,  SUESSMUTH RODERICH ,  RECKTENWALD JUERGEN ,  HECKMANN DOROTHEE ,  WOHLLEBEN WOLFGANG

IPC: C12N15/09 ,  C07H17/00 ,  C12N1/15 ,  C12N1/19 ,  C12N1/21 ,  C12N5/10 ,  C12N9/14 ,  C12N15/52 ,  C12N15/55 ,  C12P21/02 ,  C07K9/00

Abstract: The invention relates to a process halogenation, which comprises halogenating a chemical compound in the presence of a halogenase, where the halogenase is(a) encoded by the sequence specified in SEQ ID NO: 1 or a sequence derived therefrom on the basis of the degeneracy of the genetic code, or is(b) encoded by a nucleic acid sequence which codes for a functional fragment of (a) or(c) by a sequence which hybridizes with (a) or (b) under standard conditions, or is(d) encoded by a sequence which has more than 30% identity or more than 60% similarity with the sequence specified under (a).