公开(公告)号：BR0012772A

公开(公告)日：2002-04-02

申请号：BR0012772

申请日：2000-07-27

Applicant: BASF AG

Inventor： HAUER BERNHARD ,  PLEISS JUERGEN ,  SCHWANEBERG ULRICH ,  SCHMITT JUTTA ,  FISCHER MARKUS ,  SCHMID ROLF ,  LI QING-SHAN ,  LUTZ-WAHL SABINE ,  APPEL DANIEL

IPC: C12N15/09 ,  C12M1/40 ,  C12N1/21 ,  C12N9/02 ,  C12N15/53 ,  C12P7/02 ,  C12P7/04 ,  C12P7/22 ,  C12P7/64 ,  C12P17/10 ,  C12P17/16 ,  C12Q1/26 ,  C12R1/19 ,  C12N15/70

Abstract: The invention relates to novel cytochrome P450 monooxygenases comprising a modified substrate specificity, to nucleotide sequences which code therefor, to expression constructs and vectors containing these sequences, and to microorganisms transformed therewith. The invention also relates to methods for microbiologically oxidizing different organic substrates, such as methods for producing indigo and indirubin.

公开(公告)号：EE200200048A

公开(公告)日：2003-04-15

申请号：EEP200200048

申请日：2000-07-27

Applicant: BASF AG

Inventor： HAUER BERNHARD ,  PLEISS JUERGEN ,  SCHWANEBERG ULRICH ,  SCHMITT JUTTA ,  FISCHER MARKUS ,  SCHMID ROLF ,  LI QING-SHAN ,  LUTZ-WAHL SABINE ,  APPEL DANIEL

IPC: C12N15/09 ,  C12M1/40 ,  C12N1/21 ,  C12N9/02 ,  C12N15/53 ,  C12P7/02 ,  C12P7/04 ,  C12P7/22 ,  C12P7/64 ,  C12P17/10 ,  C12P17/16 ,  C12Q1/26 ,  C12R1/19 ,  C12N15/70

Abstract: The invention relates to novel cytochrome P450 monooxygenases comprising a modified substrate specificity, to nucleotide sequences which code therefor, to expression constructs and vectors containing these sequences, and to microorganisms transformed therewith. The invention also relates to methods for microbiologically oxidizing different organic substrates, such as methods for producing indigo and indirubin.

公开(公告)号：HU0202074A2

公开(公告)日：2002-09-28

申请号：HU0202074

申请日：2000-07-27

Applicant: BASF AG

Inventor： APPEL DANIEL ,  FISCHER MARKUS ,  HAUER BERNHARD ,  LI QING-SHAN ,  LUTZ-WAHL SABINE ,  PLEISS JUERGEN ,  SCHMID ROLF ,  SCHMITT JUTTA ,  SCHWANEBERG ULRICH

IPC: C12N15/09 ,  C12M1/40 ,  C12N1/21 ,  C12N9/02 ,  C12N15/53 ,  C12P7/02 ,  C12P7/04 ,  C12P7/22 ,  C12P7/64 ,  C12P17/10 ,  C12P17/16 ,  C12Q1/26 ,  C12R1/19

Abstract: The invention relates to novel cytochrome P450 monooxygenases comprising a modified substrate specificity, to nucleotide sequences which code therefor, to expression constructs and vectors containing these sequences, and to microorganisms transformed therewith. The invention also relates to methods for microbiologically oxidizing different organic substrates, such as methods for producing indigo and indirubin.

公开(公告)号：CA2329992A1

公开(公告)日：1999-11-04

申请号：CA2329992

申请日：1999-04-13

Applicant: BASF AG

Inventor： WOHLLEBEN WOLFGANG ,  FISCHER PETER ,  HAUER BERNHARD ,  LUTZ-WAHL SABINE ,  SCHERR OLIVER ,  SCHMID ROLF D ,  SCHMIDT-DANNERT CLAUDIA

IPC: C07C403/16 ,  C12P1/06 ,  C12P7/02 ,  C12P7/26 ,  C12R1/465

Abstract: The invention relates to a method for oxidising substituted trimethylcyclohexenyl compounds in the presence of microorganisms of the actinomycetal order and to the use of microorganisms in oxidation reactions.

公开(公告)号：HU229450B1

公开(公告)日：2013-12-30

申请号：HU0202074

申请日：2000-07-27

Applicant: BASF AG

Inventor： HAUER BERNHARD ,  PLEISS JUERGEN ,  SCHWANEBERG ULRICH ,  SCHMITT JUTTA ,  FISCHER MARKUS ,  SCHMID ROLF ,  LI QING-SHAN ,  LUTZ-WAHL SABINE ,  APPEL DANIEL

IPC: C12N15/09 ,  C12N15/53 ,  C12M1/40 ,  C12N1/21 ,  C12N9/02 ,  C12N15/70 ,  C12P7/02 ,  C12P7/04 ,  C12P7/22 ,  C12P7/64 ,  C12P17/10 ,  C12P17/16 ,  C12Q1/26 ,  C12R1/19

公开(公告)号：CA2380186A1

公开(公告)日：2001-02-01

申请号：CA2380186

申请日：2000-07-27

Applicant: BASF AG

Inventor： PLEISS JUERGEN ,  HAUER BERNHARD ,  SCHWANEBERG ULRICH ,  SCHMITT JUTTA ,  FISCHER MARKUS ,  SCHMID ROLF ,  LI QING-SHAN ,  LUTZ-WAHL SABINE ,  APPEL DANIEL

IPC: C12N15/09 ,  C12M1/40 ,  C12N1/21 ,  C12N9/02 ,  C12N15/53 ,  C12P7/02 ,  C12P7/04 ,  C12P7/22 ,  C12P7/64 ,  C12P17/10 ,  C12P17/16 ,  C12Q1/26 ,  C12R1/19 ,  C12N15/70

Abstract: The invention relates to novel cytochrome P450 monooxygenases comprising a modified substrate specificity, to nucleotide sequences which code therefor, to expression constructs and vectors containing these sequences, and to microorganisms transformed therewith. The invention also relates to methods for microbiologically oxidizing different organic substrates, such as method s for producing indigo and indirubin.

公开(公告)号：DE19818665A1

公开(公告)日：1999-10-28

申请号：DE19818665

申请日：1998-04-27

Applicant: BASF AG

Inventor： HAUER BERNHARD ,  WOHLLEBEN WOLFGANG ,  FISCHER PETER ,  LUTZ-WAHL SABINE ,  SCHMIDT-DANNERT CLAUDIA ,  SCHMID ROLF D ,  SCHERR OLIVER

IPC: C07C403/16 ,  C12P1/06 ,  C12P7/02 ,  C12P7/26 ,  C12R1/465 ,  C07C45/64 ,  C07C49/242 ,  C07C45/28 ,  C07C49/603 ,  C07C49/647 ,  C07B41/02 ,  C07B41/06

Abstract: Hydroxy and/or oxo groups are introduced into trimethyl-cyclohexene compounds (I) by selective microbiological oxidation using Actinomycetales. Oxidation of trimethyl-cyclohexene derivatives of formula (I) to hydroxy and/or oxo derivatives of formula (II) is effected in presence of bacteria of the order Actinomycetales. R1 = optionally substituted, optionally unsaturated 1-8C alkyl; R2, R3 = H, =O or OH, provided that at least one is other than H; a, b = additional bond in one of the two indicated positions. AN Independent claim is included for the use of the above bacteria for the oxidation of (I).

公开(公告)号：CA2380186C

公开(公告)日：2012-03-13

申请号：CA2380186

申请日：2000-07-27

Applicant: BASF AG

Inventor： HAUER BERNHARD ,  PLEISS JUERGEN ,  SCHWANEBERG ULRICH ,  SCHMITT JUTTA ,  FISCHER MARKUS ,  SCHMID ROLF ,  LI QING-SHAN ,  LUTZ-WAHL SABINE ,  APPEL DANIEL

IPC: C12N15/09 ,  C12N15/53 ,  C12M1/40 ,  C12N1/21 ,  C12N9/02 ,  C12N15/70 ,  C12P7/02 ,  C12P7/04 ,  C12P7/22 ,  C12P7/64 ,  C12P17/10 ,  C12P17/16 ,  C12Q1/26 ,  C12R1/19

Abstract: The invention relates to novel cytochrome P450 monooxygenases comprising a modified substrate specificity, to nucleotide sequences which code therefor, to expression constructs and vectors containing these sequences, and to microorganisms transformed therewith. The invention also relates to methods for microbiologically oxidizing different organic substrates, such as methods for producing indigo and indirubin.

公开(公告)号：NO20020380L

公开(公告)日：2002-03-22

申请号：NO20020380

申请日：2002-01-24

Applicant: BASF AG

Inventor： HAUER BERNHARD ,  PLEISS JUERGEN ,  SCHWANNEBERG ULRICH ,  SCHMITT JUTTA ,  FISCHER MARKUS ,  SCHMID ROLF D ,  LI QING-SHAN ,  LUTZ-WAHL SABINE ,  APPEL DANIEL

IPC: C12N15/09 ,  C12M1/40 ,  C12N1/21 ,  C12N9/02 ,  C12N15/53 ,  C12P7/02 ,  C12P7/04 ,  C12P7/22 ,  C12P7/64 ,  C12P17/10 ,  C12P17/16 ,  C12Q1/26 ,  C12R1/19 ,  C12N

Abstract: The invention relates to novel cytochrome P450 monooxygenases comprising a modified substrate specificity, to nucleotide sequences which code therefor, to expression constructs and vectors containing these sequences, and to microorganisms transformed therewith. The invention also relates to methods for microbiologically oxidizing different organic substrates, such as methods for producing indigo and indirubin.

公开(公告)号：NO20020380D0

公开(公告)日：2002-01-24

申请号：NO20020380

申请日：2002-01-24

Applicant: BASF AG

Inventor： HAUER BERNHARD ,  PLEISS JUERGEN ,  SCHWANNEBERG ULRICH ,  SCHMITT JUTTA ,  FISCHER MARKUS ,  SCHMID ROLF D ,  LI QING-SHAN ,  LUTZ-WAHL SABINE ,  APPEL DANIEL

IPC: C12N15/09 ,  C12M1/40 ,  C12N1/21 ,  C12N9/02 ,  C12N15/53 ,  C12P7/02 ,  C12P7/04 ,  C12P7/22 ,  C12P7/64 ,  C12P17/10 ,  C12P17/16 ,  C12Q1/26 ,  C12R1/19 ,  C12N

Abstract: The invention relates to novel cytochrome P450 monooxygenases comprising a modified substrate specificity, to nucleotide sequences which code therefor, to expression constructs and vectors containing these sequences, and to microorganisms transformed therewith. The invention also relates to methods for microbiologically oxidizing different organic substrates, such as methods for producing indigo and indirubin.