公开(公告)号：WO2016050816A2

公开(公告)日：2016-04-07

申请号：PCT/EP2015/072506

申请日：2015-09-30

Applicant: BASF SE

Inventor： BUDDE, Michael ,  BRAUN, Michael ,  DAEUWEL, Juergen ,  OEDMAN, Peter ,  BALDENIUS, Kai-Uwe ,  KLEINER, Matthias ,  FREYER, Stephan

IPC: C12P13/02

CPC classification number: C12P13/02 ,  C12N9/78 ,  C12N9/80 ,  C12Y305/01004 ,  C12Y305/05001

Abstract: The present invention relates to means and methods for producing an amide compound from a nitrile compound with less acrylic acid as by-product using a Nitrile hydratase (NHase) and Amidase producing microorganism as biocatalyst. Also provided is an aqueous amide compound obtained by the methods of the invention as well as a composition comprising acrylamide or polyacrylamide as well as a dried microorganism exhibiting a NHase/Amidase activity ratio of at least 400 when being brought into contact with a nitrile compound to convert said nitrile compound into an amide compound.

Abstract translation: 本发明涉及使用腈水合酶（NHase）和产酰胺酶作为生物催化剂的腈水合酶作为副产物的腈化合物制备酰胺化合物的方法和方法。 还提供了通过本发明方法获得的酰胺化合物水溶液以及包含丙烯酰胺或聚丙烯酰胺的组合物以及当与腈化合物接触时显示出至少为400的NHase / Amidase活性比的干燥微生物， 将所述腈化合物转化为酰胺化合物。

公开(公告)号：WO2014090672A1

公开(公告)日：2014-06-19

申请号：PCT/EP2013/075618

申请日：2013-12-05

Applicant: BASF SE

Inventor： LANGE, Arno ,  CSIHONY, Szilard ,  KLEINER, Matthias

IPC: C08F8/02 ,  C08F2/42 ,  C08F110/10 ,  C08F8/10

CPC classification number: C08F110/10 ,  C08F2/42 ,  C08F8/02 ,  C08F8/10 ,  C08F2810/40 ,  C08G81/025 ,  C08F4/005

Abstract: Beschrieben wird ein Verfahren zur Herstellung von funktionalisierten Polyisobutenen, bei dem man Isobuten oder ein Isobuten-haltiges Monomerengemisch in Gegenwart einer Lewis-Säure und eines Initiators polymerisiert und wobei die Polymerisation mit einem Gemisch aus einem Phenol und einer Lewissäure und/oder einer Brönstedsäure abgebrochen wird. Die terminalen Phenolgruppen können derivatisiert oder zu Cyclohexanolsystemen reduziert werden.

Abstract translation: 公开了一种用于制备官能化聚异丁烯的方法，其中异丁烯或在路易斯酸和引发剂，并用苯酚和路易斯酸布朗斯台德酸的混合物和/或聚合的存在下含异丁烯的单体混合物聚合中止 ， 终端酚基团可以被衍生化或减小到Cyclohexanolsystemen。

公开(公告)号：EP3201349A2

公开(公告)日：2017-08-09

申请号：EP15794829.0

申请日：2015-09-30

Applicant: BASF SE

Inventor： BUDDE, Michael ,  BRAUN, Michael ,  DAEUWEL, Juergen ,  OEDMAN, Peter ,  BALDENIUS, Kai-Uwe ,  KLEINER, Matthias ,  FREYER, Stephan

IPC: C12P13/02

CPC classification number: C12P13/02 ,  C12N9/78 ,  C12N9/80 ,  C12Y305/01004 ,  C12Y305/05001

Abstract: The present invention relates to means and methods for producing an amide compound from a nitrile compound with less acrylic acid as by-product using a Nitrile hydratase (NHase) and Amidase producing microorganism as biocatalyst. Also provided is an aqueous amide compound obtained by the methods of the invention as well as a composition comprising acrylamide or polyacrylamide as well as a dried microorganism exhibiting a NHase/Amidase activity ratio of at least 400 when being brought into contact with a nitrile compound to convert said nitrile compound into an amide compound.

Abstract translation: 本发明涉及使用腈水合酶（NHase）和产酰胺酶微生物作为生物催化剂由腈化合物和少量丙烯酸副产物生产酰胺化合物的方法和方法。 还提供了通过本发明的方法获得的含水酰胺化合物以及包含丙烯酰胺或聚丙烯酰胺的组合物以及当与腈化合物接触时显示至少400的NHase /酰胺酶活性比的干燥微生物与 将所述腈化合物转化成酰胺化合物。

公开(公告)号：EP2928928A1

公开(公告)日：2015-10-14

申请号：EP13801573.0

申请日：2013-12-05

Applicant: BASF SE

Inventor： LANGE, Arno ,  CSIHONY, Szilard ,  KLEINER, Matthias

IPC: C08F8/02 ,  C08F2/42 ,  C08F110/10 ,  C08F8/10

CPC classification number: C08F110/10 ,  C08F2/42 ,  C08F8/02 ,  C08F8/10 ,  C08F2810/40 ,  C08G81/025 ,  C08F4/005

Abstract: The invention relates to a method for producing functionalized polyisobutylenes, wherein isobutylene or a monomer mixture containing isobutylene is polymerized in the presence of a Lewis acid and an initiator and wherein the polymerization is terminated by means of a mixture of a phenol and a Lewis acid and/or a Brønsted-Lowry acid. The terminal phenol groups can be derivatized, or reduced to cyclohexanol systems.

Abstract translation: 描述的是制备官能化的聚异丁烯的方法，其中异丁烯或含异丁烯的单体混合物在路易斯酸和引发剂的存在下聚合，并且用苯酚和路易斯酸的混合物终止聚合 和/或布朗斯台德酸。 末端苯酚基团可以被衍生化或还原成环己醇体系。

公开(公告)号：EP3201348B1

公开(公告)日：2019-01-23

申请号：EP15788335.6

申请日：2015-09-30

Applicant: BASF SE

Inventor： BRAUN, Michael ,  DAEUWEL, Juergen ,  LANG, Hans-Juergen ,  OEDMAN, Peter ,  BALDENIUS, Kai-Uwe ,  KLEINER, Matthias ,  KIEFER, Michael ,  FREYER, Stephan ,  BUDDE, Michael

IPC: C12P13/02

公开(公告)号：EP3741781A1

公开(公告)日：2020-11-25

申请号：EP19175602.2

申请日：2019-05-21

Applicant: BASF SE

Inventor： ROMEIS, Juergen ,  JANSSEN, Nicole ,  KLEINER, Matthias ,  KREMZOW-GRAW, Doris ,  ZIMMERMANN, Tobias Joacim

IPC: C08F2/40 ,  C08L33/26

Abstract: The presently claimed invention is directed to a method for the inhibition of the polymerization of a solution comprising acrylamide monomer comprising at least the steps of:
i) detecting a first initiation point and a second initiation point, and
ii) charging at least one polymerization inhibitor to the solution, when either one of the first initiation point and the second initiation point is met;
wherein the first initiation point is an oxygen content of ≤ 1.0 ppm in the solution and the second initiation point is an increase in the relative viscosity of the solution in the range from + 1.0 % to 80 %.

公开(公告)号：EP2906604A1

公开(公告)日：2015-08-19

申请号：EP13774402.5

申请日：2013-10-07

Applicant: BASF SE

Inventor： LANGE, Arno ,  KIEFER, Matthias ,  KLEINER, Matthias ,  CSIHONY, Szilard ,  POSSELT, Dietmar

IPC: C08F110/10 ,  C08F4/00

CPC classification number: C08F110/10 ,  C08F8/00 ,  C08F10/10 ,  C08F4/12 ,  C08F4/06 ,  C08F4/00

Abstract: A method for producing bifunctional polyisobutenes, according to which method isobutene or a monomer mixture containing isobutene is polymerized in the presence of a Lewis acid and a compound of formula (I), where X represents an acyl radical or the radical of an organic or inorganic acid group, R
1 to R
4 are identical or different and represent hydrogen or a hydrocarbyl.

公开(公告)号：EP3201348A1

公开(公告)日：2017-08-09

申请号：EP15788335.6

申请日：2015-09-30

Applicant: BASF SE

Inventor： BRAUN, Michael ,  DAEUWEL, Juergen ,  LANG, Hans-Juergen ,  OEDMAN, Peter ,  BALDENIUS, Kai-Uwe ,  KLEINER, Matthias ,  KIEFER, Michael ,  FREYER, Stephan ,  BUDDE, Michael

IPC: C12P13/02

CPC classification number: C12P13/02 ,  C07C233/09 ,  C08F20/56 ,  C08L33/26 ,  C08L2201/54 ,  C09K8/588 ,  C12Y402/01084 ,  D21H17/375

Abstract: The present invention relates to methods for preparing an aqueous acrylamide solution having a low acrylic acid concentration. In addition, the present invention relates to methods for reducing the acrylic acid concentration of an aqueous acrylamide solution. The methods involve a bioconversion of acrylonitrile to acrylamide in the presence of a biocatalyst, wherein during the bioconversion the content of acrylonitrile is maintained at 0.3 w/w % or more referred to the total weight of the composition in the reactor. Also provided is an aqueous acrylamide solution which is obtained by the methods of the present invention. Furthermore, the present invention is related to an acrylamide homopolymer or copolymer obtained by polymerizing the acrylamide of the aqueous solution.

Abstract translation: 本发明涉及制备具有低丙烯酸浓度的丙烯酰胺水溶液的方法。 另外，本发明涉及降低丙烯酰胺水溶液的丙烯酸浓度的方法。 该方法包括在生物催化剂存在下将丙烯腈生物转化成丙烯酰胺，其中在生物转化过程中丙烯腈的含量保持在反应器中组合物总重量的0.3w / w％或更多。 还提供了通过本发明的方法获得的丙烯酰胺水溶液。 此外，本发明涉及通过聚合水溶液的丙烯酰胺而获得的丙烯酰胺均聚物或共聚物。

公开(公告)号：EP2751143A1

公开(公告)日：2014-07-09

申请号：EP12753968.2

申请日：2012-08-30

Applicant: BASF SE

Inventor： HESSE, Pascal ,  FLEISChmann, Sven ,  BECKER, Florian ,  MÜHLBACH, Klaus ,  HUNGENBERG, Klaus-Dieter ,  BRYM, Markus ,  KLEINER, Matthias

IPC: C08F4/10 ,  C08F4/40 ,  C08F293/00 ,  C08F297/00

CPC classification number: C08F2/01 ,  C08F2/38 ,  C08F4/40 ,  C08F220/14 ,  C08F293/005 ,  C08F2220/1825 ,  C08F2438/01 ,  C08F2438/02

Abstract: Method for producing polymers by means of controlled radical polymerisation, wherein the polymerisation of one or several radically polymerisable monomers of general formula (I), where R
1 , R
2 , R
3 are H, C
1 -C
4 alkyl, R
4 is C(=O)OR
5 , C(=O)NHR
15 , C(=O)NR
5 R
6 , OC(=O)CH
3 , C(=O)OH, CN, aryl, hetaryl, C(=O)OR
5 OH, C(=O)OR
5 Si(OR
5 )
3 , halogen, NHC(O)H, P(=O)(OR
7 )
2 , R
5 is C
1 -C
20 alkyl, R
15 is C
1 -C
20 -alkyl, R
6 is C
1 -C
20 alkyl, and R
7 is H, C
1 -C
20 alkyl, occurs in the presence of a. one or several catalysts containing Cu in the form of Cu(0), Cu(l), Cu (II) or mixtures thereof, b. one or several initiators selected from the group of organic halogenides or pseudohalogenides, c. one or several ligands, d. optionally one or several solvents, and e. optionally one or several inorganic halogenide salts, said method consisting of the following steps i) addition of the catalyst a., ii) optional addition of monomers of general formula (I), iii) optional addition of solvent d., iv) addition of ligand c., v) addition of initiator b., vi) addition of monomers of general formula (I), and vii) optional addition of inorganic halogenide salts e., on the proviso that the addition of at least some of the monomers of general formula (I) occurs immediately before or shortly after the last of the steps i), iv) and v).

公开(公告)号：EP2496611A1

公开(公告)日：2012-09-12

申请号：EP10773307.3

申请日：2010-11-02

Applicant: BASF SE

Inventor： KLEINER, Matthias ,  LOTH, Wolfgang ,  BRYM, Markus ,  GÜTLICH-HAUK, Elke ,  URTEL, Bolette ,  WIRSCHEM, Ruth ,  DETERING, Jürgen

IPC: C08F6/00 ,  C08F6/06 ,  C08F6/10 ,  B01F5/06 ,  B01F13/00 ,  B01J19/00 ,  C08F20/06

CPC classification number: C08F6/06 ,  B01J19/0093 ,  B01J2219/00006 ,  B01J2219/00033 ,  B01J2219/00783 ,  B01J2219/00858 ,  B01J2219/00873 ,  B01J2219/00889 ,  C08F2/01 ,  C08F2/10 ,  C08F6/003 ,  C08F6/10 ,  C08F20/06 ,  C08L33/02

Abstract: The invention relates to a method for producing aqueous solutions of homo or copolymers of acrylic acid by means of radical polymerization of acrylic acid and optional water-soluble, monoethylene unsaturated comonomers in an aqueous medium in the presence of at least one water-soluble initiator and at least one water-soluble regulator, wherein the polymerization is performed by means of a continuous process, and wherein low-molecular components are at least partially separated out of the aqueous polymer solution obtained after polymerization. Microstructured mixers and reactors are preferably used for the polymerization. At least one reactor and/or mixer having microstructures are preferably used for the process.