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    CONTINUOUS PROCESS FOR THE SYNTHESIS OF GRAFT POLYMERS BASED ON POLYETHERS
    12.
    发明申请
    CONTINUOUS PROCESS FOR THE SYNTHESIS OF GRAFT POLYMERS BASED ON POLYETHERS 有权
    聚合物聚合物合成的连续工艺

    公开(公告)号：US20130253089A1

    公开(公告)日：2013-09-26

    申请号：US13787949

    申请日：2013-03-07

    Applicant: BASF SE

    Inventor： Faissal-Ali El-Toufaili ,  Michaela Heussler ,  Christian Schwede ,  Aaron Flores-Figueroa ,  Rainer Dobrawa ,  Dieter Boeckh ,  Wolfgang Loth ,  Gerd Konrad

    IPC: C08F2/01

    CPC classification number: C08F2/01 ,  C08F283/06 ,  C08F218/08

    Abstract: The invention relates to a continuous process for the preparation of amphiphilic graft polymers, wherein a vinyl ester component (B) composed of vinyl acetate and/or vinyl propionate (B1) and, if desired, a further ethylenically unsaturated monomer (B2), is polymerized in the presence of a polyalkylene oxide (A), a free radical-forming initiator (C) and, if desired, an additive (D), at a mean polymerization temperature at which the initiator (C) has a decomposition half-time of from 1 to 500 min, in at least one tubular reactor segment with a feed side and an outlet side, through which the reaction mixture comprising at least a part of component (A) to (C), and if desired (D), streams, a tubular reactor segment and the use of the inventive amphiphilic graft polymer. The invention further relates to an inventive amphiphilic graft polymer and the use thereof.

    Abstract translation: 本发明涉及制备两亲性接枝聚合物的连续方法，其中由乙酸乙烯酯和/或丙酸乙烯酯（B1）组成的乙烯基酯组分（B）和如果需要，另外的烯键式不饱和单体（B2）是 在聚亚烷基氧化物（A），自由基形成引发剂（C）和根据需要的情况下，在引发剂（C）具有分解半衰期的平均聚合温度下，如果需要，添加剂 在至少一个具有进料侧和出口侧的管状反应器段中，反应混合物通过该混合物至少包含组分（A）至（C）和（如果需要的话）（D）， 流，管式反应器段和本发明的两亲接枝聚合物的用途。 本发明还涉及本发明的两亲性接枝聚合物及其用途。

    Use Of Polyether-Based And Vinyl Monomer-Based Copolymers As Binders For Dosing Forms Comprising Solid Active Ingredients
    13.
    发明申请
    Use Of Polyether-Based And Vinyl Monomer-Based Copolymers As Binders For Dosing Forms Comprising Solid Active Ingredients 审中-公开
    使用基于聚醚和乙烯基单体的共聚物作为包含固体活性成分的剂型的粘合剂

    公开(公告)号：US20130123373A1

    公开(公告)日：2013-05-16

    申请号：US13732833

    申请日：2013-01-02

    Applicant: BASF SE

    Inventor： Kathrin Meyer-Böhm ,  Rainer Dobrawa ,  Angelika Maschke ,  Karl Kolter

    IPC: A61K47/34 ,  A61K9/20

    CPC classification number: A61K47/34 ,  A61K9/1641 ,  A61K9/2031 ,  A61K9/2095

    Abstract: The use of water-soluble or water-dispersible copolymers which are obtained by free radical-initiated polymerization of a mixture of i) 30 to 80% by weight N-vinyllactam, ii) 10 to 50% by weight vinylacetate and iii) 10 to 50% by weight of a polyether, with the proviso that the total of i), ii) and iii) is equal to 100% by weight, as binders for producing solid active ingredient-containing dosage forms.

    Abstract translation: 使用水溶性或水分散性共聚物，其通过i）30至80重量％的N-乙烯基内酰胺的混合物的自由基引发聚合获得，ii）10至50重量％的乙酸乙烯酯和iii）10至 50重量％的聚醚，条件是i），ii）和iii）的总量等于100重量％，作为用于生产含固体活性成分的剂型的粘合剂。

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