公开(公告)号：WO2009129256A8

公开(公告)日：2014-10-16

申请号：PCT/US2009040551

申请日：2009-04-14

Applicant: BATTELLE MEMORIAL INSTITUTE ,  HOLLADAY JOHNATHAN E ,  MUZATKO DANIELLE S ,  WHITE JAMES F ,  ZACHER ALAN H

Inventor： HOLLADAY JOHNATHAN E ,  MUZATKO DANIELLE S ,  WHITE JAMES F ,  ZACHER ALAN H

IPC: C07C29/60 ,  C07C31/20

CPC classification number: C07C29/132 ,  C07C29/60 ,  C07C31/205

Abstract: Hydrogenolysis systems are provided that can include a reactor housing an Ru-comprising hydrogenolysis catalyst and wherein the contents of the reactor is maintained at a neutral or acidic pH. Reactant reservoirs within the system can include a polyhydric alcohol compound and a base, wherein a weight ratio of the base to the compound is less than 0.05. Systems also include the product reservoir comprising a hydrogenolyzed polyhydric alcohol compound and salts of organic acids, and wherein the moles of base are substantially equivalent to the moles of salts or organic acids. Processes are provided that can include an Ru-comprising catalyst within a mixture having a neutral or acidic pH. A weight ratio of the base to the compound can be between 0.01 and 0.05 during exposing.

Abstract translation: 提供了氢解系统，其可以包括容纳含Ru的氢解催化剂的反应器，并且其中反应器的内容物保持在中性或酸性pH。 系统内的反应物储存器可以包括多元醇化合物和碱，其中碱与化合物的重量比小于0.05。 系统还包括包含氢解的多元醇化合物和有机酸的盐的产物储存器，其中碱的摩尔数基本上等于盐或有机酸的摩尔数。 提供了可以在具有中性或酸性pH的混合物中包含含Ru的催化剂的方法。 在曝光期间，碱与化合物的重量比可以在0.01和0.05之间。

公开(公告)号：WO2009029540A3

公开(公告)日：2009-09-17

申请号：PCT/US2008074090

申请日：2008-08-22

Applicant: BATTELLE MEMORIAL INSTITUTE ,  PETERSON THOMAS H ,  HOLLADAY JOHNATHAN E ,  ZACHER ALAN H ,  GRAY MICHEL J ,  WERPY TODD A ,  WHITE JAMES F

Inventor： PETERSON THOMAS H ,  HOLLADAY JOHNATHAN E ,  ZACHER ALAN H ,  GRAY MICHEL J ,  WERPY TODD A ,  WHITE JAMES F

IPC: C07C45/52 ,  B01J27/16 ,  C07C47/22

CPC classification number: C07C45/52 ,  C07C49/17 ,  C07C47/22

Abstract: Chemical production processes are provided that include exposing a reactant composition to a catalyst composition to form a product composition, with the reactant composition including a multihydric alcohol compound and the catalyst composition being effective to dehydrate at least a portion of the multihydric alcohol compound. Embodiments of the process provide that the reactant composition is exposed to the catalyst composition for less than about 0.25 seconds and/or that the catalyst is maintained at a temperature of from about 2800C to about 3200C. Processes utilizing a reactant composition including a multihydric alcohol compound and an inert compound are also provided.

Abstract translation: 提供化学生产方法，其包括将反应物组合物暴露于催化剂组合物以形成产物组合物，其中反应物组合物包含多元醇化合物并且催化剂组合物有效使至少一部分多元醇化合物脱水。 该方法的实施方案规定反应物组合物暴露于催化剂组合物小于约0.25秒和/或催化剂保持在约280℃至约320℃的温度。 还提供了利用包含多元醇化合物和惰性化合物的反应物组合物的方法。

公开(公告)号：WO2004058708B1

公开(公告)日：2004-09-23

申请号：PCT/US0340106

申请日：2003-12-16

Applicant: BATTELLE MEMORIAL INSTITUTE ,  WERPY TODD A ,  FRYE JOHN G JR ,  WHITE JAMES F ,  HOLLADAY JOHNATHAN E ,  ZACHER ALAN H

Inventor： WERPY TODD A ,  FRYE JOHN G JR ,  WHITE JAMES F ,  HOLLADAY JOHNATHAN E ,  ZACHER ALAN H

IPC: C07D207/40 ,  C07D207/404

CPC classification number: C07D207/404 ,  C07D207/267

Abstract: The invention includes methods of processing an initial di-carbonyl compound by conversion to a cyclic compound. The cyclic compound is reacted with an alkyating agent to form a derivative having an alkylated ring nitrogen. The invention encompasses a method of producing an N-alkyl product. Amonia content of a solution is adjusted to produce a ratio of ammonia to di-carboxylate compound of from about 1:1 to about 1.5:1. An alkylating agent is added and the initial compound is alkylated and cyclized. The invention includes methods of making N-methyl pyrrolidinone (NMP). Aqueous ammonia and succinate is introduced into a vessel and ammonia is adjusted to provide a ratio of ammonia to succinate of less than 2:1. A methylating agent is reacted with succinate at a temperature of from greater than 100 °C to about 400 °C to produce N-methyl succinimide which is purified and hydrogenated to form NMP.

Abstract translation: 本发明包括通过转化成环状化合物来处理初始二羰基化合物的方法。 该环状化合物与烷基化剂反应形成具有烷基化环氮的衍生物。 本发明包括生产N-烷基产物的方法。 调节溶液的氨含量以产生约1:1至约1.5:1的氨与二羧酸盐化合物的比率。 加入烷基化试剂并将初始化合物烷基化并环化。 本发明包括制备N-甲基吡咯烷酮（NMP）的方法。 将氨水和琥珀酸盐引入容器中并调节氨以提供小于2：1的氨与琥珀酸盐的比例。 使甲基化剂与琥珀酸酯在大于100℃至约400℃的温度下反应以产生N-甲基琥珀酰亚胺，将其纯化并氢化以形成NMP。