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公开(公告)号：DE69119787T2
公开(公告)日：1997-01-23
申请号：DE69119787
申请日：1991-06-26
Applicant: BAXTER INT
Inventor： PRINCE PAUL R , MILLER WILLIAM , BENJAMIN GRANT S
Abstract: A simplified fluid separation method and device usable for various apheresis procedures, including plasmapheresis. At least one pump is utilized to draw a first fluid (e.g. whole blood) into a separation device. The separation device then operates to separate the fluid (e.g. whole blood) into first and second fluid fractions (e.g. a cell concentrate and blood plasma). The first and second fluid fractions are pumped from the separation device to separate first and second fluid fraction containers, both of which are positioned on a single weighing device, such as an electronic load cell. At least one of the fluid fractions is subsequently removed from its fluid fraction container and returned to the human subject or other fluid source. Weights recorded by the single weighing device are then utilized to calculate the actual weights of fluid and/or fluid fractions pumped by at least one pump during the procedure. Such actual weights of fluid and/or fluid fractions are then utilized to calculate new pump flow constants, thereby enabling the calibration of the pump(s) to be corrected, on the basis of such new pump flow constants, prior to subsequent utilization of the pump(s) for pumping the fluid and/or fluid fractions. The single weighing device may also be utilized to monitor the weight change or rate of weight change occurring as the fluid fractions are pumped into and/or out of the fluid fraction containers, thereby providing a means for monitoring and verifying the pressures and flow rates within the system.
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公开(公告)号：CA1324583C
公开(公告)日：1993-11-23
申请号：CA589889
申请日：1989-02-02
Applicant: BAXTER INT
Inventor： PRINCE PAUL R
Abstract: ADAPTIVE FILTRATE FLOW CONTROL SYSTEM USING CONTROLLED REDUCTION IN FILTER EFFICIENCY The efficiency of a blood plasmapheresis filter is purposefully reduced at low input blood flow rates so as to prevent possibly excessive hematocrit which may make it difficult or impossible to handle the resulting blood cell concentrate (e.g., for infusion purposes) and/or which may cause accompanying red cell damage. Where filter efficiency is a function of rpm of a spinning element, such controlled reduction may be achieved by simply controlling spinner rpm as a function (e.g., linear over at least some range) of the input blood flow rate.
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公开(公告)号：AU600711B2
公开(公告)日：1990-08-23
申请号：AU7085387
申请日：1987-02-25
Applicant: BAXTER INT
Inventor： IV WARREN P WILLIAMSON , PRINCE PAUL R
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公开(公告)号：AU3056989A
公开(公告)日：1989-08-25
申请号：AU3056989
申请日：1989-02-02
Applicant: BAXTER INT
Inventor： PRINCE PAUL R
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公开(公告)号：AU7121187A
公开(公告)日：1988-09-26
申请号：AU7121187
申请日：1987-02-25
Applicant: BAXTER INT
Inventor： PRINCE PAUL R
Abstract: A blood fractionating apparatus comprises a first length of tubing (112,116) connected between a needle and a blood first fraction outlet (118). A separator (130) is connected in the tubing (112,116) between the needle and outlet (118). A blood pump (101) and a first fraction pump (102) are connected in the tubing respectively upstream and downstream of the separator (130). A second length of tubing (120) is connected at one end with the separator (130) and at its other end has a second fraction outlet (121). A haemostat (122) is provided along the second tubing length (120), upstream of the second fraction outlet (121). A sensor (200), operable to sense fluid pressure or volume in the first tubing length (112,116), is connected to the first tubing length (112,116) upstream of the separator (130). A microprocessor is connected with the sensor (200) and pumps (101,102) to derive relative flow characteristics of the individual pumps (101,102).
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Patent Agency Ranking
公开(公告)号：DE69132942T2
公开(公告)日：2002-11-07
申请号：DE69132942
申请日：1991-03-28
Applicant: BAXTER INT
Inventor： FORD MICHAEL G , PRINCE PAUL R
Abstract: Fluid is flowed from a source container to a weighing container and from the weighing container, the flow to the weighing container being controlled to keep the weight of fluid in the weighing container within predetermined limits. A warning may be provided if the amount in the weighing container falls below a warning amount, fluid then being directed to the container from a different source. Flow from the weighing container may be shut down, if the weight falls below a fail safe amount.
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公开(公告)号：DE69132942D1
公开(公告)日：2002-04-04
申请号：DE69132942
申请日：1991-03-28
Applicant: BAXTER INT
Inventor： FORD MICHAEL G , PRINCE PAUL R
Abstract: Fluid is flowed from a source container to a weighing container and from the weighing container, the flow to the weighing container being controlled to keep the weight of fluid in the weighing container within predetermined limits. A warning may be provided if the amount in the weighing container falls below a warning amount, fluid then being directed to the container from a different source. Flow from the weighing container may be shut down, if the weight falls below a fail safe amount.
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公开(公告)号：DE3854927T2
公开(公告)日：1996-09-05
申请号：DE3854927
申请日：1988-11-22
Applicant: BAXTER INT
Inventor： SCHOENDORFER DONALD W , PRINCE PAUL R
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公开(公告)号：AU613148B2
公开(公告)日：1991-07-25
申请号：AU2944488
申请日：1988-11-22
Applicant: BAXTER INT
Inventor： SCHOENDORFER DONALD W , PRINCE PAUL R
IPC: A61M1/36
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公开(公告)号：AU597637B2
公开(公告)日：1990-06-07
申请号：AU7121187
申请日：1987-02-25
Applicant: BAXTER INT
Inventor： PRINCE PAUL R
Abstract: A blood fractionating apparatus comprises a first length of tubing (112,116) connected between a needle and a blood first fraction outlet (118). A separator (130) is connected in the tubing (112,116) between the needle and outlet (118). A blood pump (101) and a first fraction pump (102) are connected in the tubing respectively upstream and downstream of the separator (130). A second length of tubing (120) is connected at one end with the separator (130) and at its other end has a second fraction outlet (121). A haemostat (122) is provided along the second tubing length (120), upstream of the second fraction outlet (121). A sensor (200), operable to sense fluid pressure or volume in the first tubing length (112,116), is connected to the first tubing length (112,116) upstream of the separator (130). A microprocessor is connected with the sensor (200) and pumps (101,102) to derive relative flow characteristics of the individual pumps (101,102).
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