中科微点-全球专利检索

  1. Login
  2. Sign Up

Search Results

23 records (took 0.029 seconds)

    SAMPLE AND METHOD OF SAMPLE PREPARATION
    12.
    发明公开
    SAMPLE AND METHOD OF SAMPLE PREPARATION 审中-公开

    公开(公告)号：EP4075478A1

    公开(公告)日：2022-10-19

    申请号：EP22162263.2

    申请日：2013-10-22

    Applicant: Fluidigm Canada Inc.

    Inventor： BARANOV, Vladimir

    IPC: H01J49/04 ,  G01N15/10 ,  G01N33/48 ,  G01N1/04

    Abstract: A combination of mutually exclusive cell-based analytical techniques can be applied to the same group of cells for analysis. The same group of cells can be prepared for analysis by each technique resulting with candidate cells targeted for mass cytometry analysis. This configuration allows for the correlation of the information between each technique to produce a matrix of multi dimension of cellular information with the same group of cells.

    CELL ANALYSIS BY MASS CYTOMETRY
    14.
    发明公开
    CELL ANALYSIS BY MASS CYTOMETRY 审中-公开
    细胞色素细胞分析

    公开(公告)号：EP2912433A1

    公开(公告)日：2015-09-02

    申请号：EP13849206.1

    申请日：2013-10-22

    Applicant: Fluidigm Canada Inc.

    Inventor： BARANOV, Vladimir

    IPC: G01N15/10 ,  C12M1/34 ,  C12Q1/00 ,  C40B20/02 ,  C40B20/04 ,  H01J49/40

    CPC classification number: G01N15/10 ,  C12M1/343 ,  G01N1/04 ,  G01N33/4833 ,  G01N33/569 ,  G01N2001/045 ,  G01N2015/1006 ,  G01N2015/1093

    Abstract: A combination of mutually exclusive cell-based analytical techniques can be applied to the same group of cells for analysis. The same group of cells can be prepared for analysis by each technique resulting with candidate cells targeted for mass cytometry analysis. This configuration allows for the correlation of the information between each technique to produce a matrix of multi dimension of cellular information with the same group of cells.

    Abstract translation: 互相排斥的基于细胞的分析技术的组合可应用于同一组细胞进行分析。 可以制备相同组的细胞用于通过每种技术进行分析，从而产生靶向用于大规模细胞计数分析的候选细胞。 该配置允许每种技术之间的信息相关性，以产生具有相同组单元的多维蜂窝信息的矩阵。

    POLYMER BACKBONE ELEMENT TAGS
    15.
    发明公开
    POLYMER BACKBONE ELEMENT TAGS 有权
    POLYMERRÜCKGRATELEMENTETIKETTEN

    公开(公告)号：EP2960263A1

    公开(公告)日：2015-12-30

    申请号：EP15177058.3

    申请日：2007-05-28

    Applicant: Fluidigm Canada Inc.

    Inventor： WINNIK, Mitchell, A. ,  NITZ, Mark ,  BARANOV, Vladimir ,  LOU, Xudong

    IPC: C08F220/36 ,  C08F8/14 ,  C08F8/32 ,  C08F8/42 ,  G01N33/532 ,  G01N33/58

    CPC classification number: C08F8/32 ,  C08F8/14 ,  C08F8/42 ,  C08F220/36 ,  C08F220/56 ,  G01N33/532 ,  G01N33/57426 ,  G01N33/58 ,  Y10T436/24

    Abstract: Element tags based on novel metal-polymer conjugates are provided for elemental analysis of analytes, including ICP-MS. A polymer backbone is functionalized to irreversibly bind metals that are selected prior to use by the user. The polymer is further functionalized to attach a linker which allows for attachment to antibodies or other affinity reagents. The polymer format allows attachment of many copies of a given isotope, which linearly improves sensitivity. The metal-polymer conjugate tags enable multiplexed assay in two formats : bulk assay, where the average biomarker distribution in the sample is diagnostic, and single cell format to distinguish a rare (for example a diseased) cell in a complex sample (for example, blood).

    Abstract translation: 提供基于新型金属 - 聚合物共轭物的元件标签用于元素分析，包括ICP-MS。 聚合物骨架被官能化以不可逆地结合在使用者使用之前选择的金属。 该聚合物进一步官能化以连接允许附着于抗体或其它亲和试剂的接头。 聚合物形式允许附加许多拷贝的给定同位素，其线性地提高灵敏度。 金属 - 聚合物缀合物标签使得能够以两种形式进行多重测定：体积测定，其中样品中的平均生物标志物分布是诊断的，以及单细胞格式以区分复杂样品中的罕见（例如患病）细胞（例如， 血液）。

    MOLECULAR CYTOMETRY
    18.
    发明公开
    MOLECULAR CYTOMETRY 审中-公开
    MOLEKULARE ZYTOMETRIE

    公开(公告)号：EP3004860A1

    公开(公告)日：2016-04-13

    申请号：EP14804873.9

    申请日：2014-05-22

    Applicant: Fluidigm Canada Inc.

    Inventor： BANDURA, Dmitry ,  BARANOV, Vladimir ,  LOBODA, Alexander ,  ORNATSKY, Olga ,  TANNER, Scott

    IPC: G01N27/62 ,  G01N33/483

    CPC classification number: G01N33/54366 ,  G01N15/1031 ,  G01N15/1404 ,  G01N15/1459 ,  G01N27/622 ,  G01N27/624 ,  G01N33/483 ,  G01N33/532 ,  G01N33/54313 ,  G01N2015/1006 ,  G01N2458/15

    Abstract: The invention relates to methods and devices for molecular cytometry. The molecular cytometer is for use in the analysis of molecular tag labeled particles. In the molecular cytometer, volatile molecular tags attached to the particles, such as cells, are released as groups of molecular tags and ionized by the method of soft ionization to produce corresponding groups of molecular ions. The molecular cytometer has two detectors, one to detect the presence of the groups of molecular ions and the other to detect mobility separated molecular ions. The mobility separated molecular ions are synchronized to correspond with the groups of molecular ions.

    Abstract translation: 本发明涉及用于分子细胞计数的方法和装置。 分子细胞仪用于分子标签标记颗粒的分析。 在分子细胞仪中，附着于颗粒（如细胞）的挥发性分子标签作为分子标签的基团释放，并通过软电离方法离子化，产生相应的分子离子组。 分子细胞仪有两个检测器，一个用于检测分子离子组的存在，另一个用于检测迁移率分离的分子离子。 迁移率分离的分子离子被同步以与分子离子的组对应。

Patent Agency Ranking