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公开(公告)号：CA2708782A1
公开(公告)日：2008-08-07
申请号：CA2708782
申请日：2008-01-18
Applicant: IBM
Inventor： POLONSKY STANISLAV , ROSSNAGEL STEPHEN , STOLOVITZKY GUSTAVO ALEJANDRO
Abstract: Techniques for controlling the position of a charged polymer (112) inside a nanopore (105) are provided. For example, one technique includes using electrostatic control to position a linear charged polymer inside a nanopore, and creating an electrostatic potential well (114) inside the nanopore, whereby the electrostatic potential well controls the position of the linear charged polymer inside the nanopore. By sequentially locking each monomer unit in the potential well (114), nanopore sequencing of DNA with single base resolution can be achieved.
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