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公开(公告)号：CA2523246A1
公开(公告)日：2004-11-11
申请号：CA2523246
申请日：2004-04-14
Applicant: KOS LIFE SCIENCES INC
Inventor： OMIDIAN HOSSEIN , GUTIERREZ-ROCCA JOSE
Abstract: The present invention features a method for the formation of superporous hydrogels using an ion-equilibration technique. Anionic polysaccharides are included in the hydrogel reaction mixture and cations are introduced either during or after hydrogel formation. Properties of the resulting hydrogel can be subsequently adjusted by treating the cation ~complexed gel with a different cation or cation mixture under equilibrating conditions. It has be en found that by properly adjusting the cations and the sequence in which they are used in the equilibration process, superporous hydrogels can be formed that are highly absorbent while maintaining favorable structural properties, including strength, ruggedness, and resiliency. It has also been found that applying appropriate dehydration conditions to them after their formation ca n further stabilize the superporous hydrogels formed by the method of the invention.
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公开(公告)号：EP1383375A4
公开(公告)日：2005-03-30
申请号：EP02725786
申请日：2002-04-23
Applicant: KOS LIFE SCIENCES INC
Inventor： GUTIERREZ-ROCCA JOSE , DUNNE JOSEPHINE , LALLY MATTHEW
IPC: A61K9/22 , A61K9/00 , A61K9/20 , A61K47/32 , A01N25/00 , A61K9/48 , A61K47/00 , A61K47/30 , A61K47/34
CPC classification number: A61K9/0065 , A61K9/209
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公开(公告)号：EP1620076A4
公开(公告)日：2010-08-25
申请号：EP04750099
申请日：2004-04-14
Applicant: KOS LIFE SCIENCES INC
Inventor： OMIDIAN HOSSEIN , GUTIERREZ-ROCCA JOSE
IPC: C08F251/00 , A61K9/22 , C08F2/44 , C08F8/44 , C08J9/08 , C08J9/28 , C08J9/40 , C08L1/28 , C08L33/14 , C08L101/14
CPC classification number: C08F251/00 , A61L27/20 , A61L27/52 , A61L27/56 , A61L31/042 , A61L31/145 , A61L31/146 , C08F2/44 , C08F8/44 , C08F251/02 , C08J3/075 , C08J9/08 , C08J9/28 , C08J9/40 , C08J2201/024 , C08J2201/0546 , C08J2203/02 , C08J2205/02 , C08J2205/022 , C08J2300/14 , C08J2301/28 , C08L2205/04
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