-
公开(公告)号：EP3044329B1
公开(公告)日：2020-04-22
申请号：EP14777230.5
申请日：2014-09-12
Applicant: Life Technologies Corporation
Inventor： LUO, Guobin , SEDOVA, Marina , LIGHT, David , JONES, Ryan , ALANJARY, Mohammad
IPC: C12Q1/6806 , C12Q1/6874
-
12.发明公开SCAFFOLDED NUCLEIC ACID POLYMER PARTICLES AND METHODS OF MAKING AND USING 有权NUCLEIC STAND系聚合物粒子及其制造方法和使用
公开(公告)号：EP2435461A1
公开(公告)日：2012-04-04
申请号：EP10780934.5
申请日：2010-05-27
Applicant: Life Technologies Corporation
Inventor： HINZ, Wolfgang , LEAMON, John H. , LIGHT, David , ROTHBERG, Jonathan M.
CPC classification number: C12N15/1093 , C12Q1/6806 , C12Q1/6834 , C12Q1/6853 , C12Q2535/122 , C12Q2563/155 , C12Q2563/159 , C12Q2565/607 , C12Q2565/537 , C12Q2565/629
Abstract: The invention provides particle compositions having applications in nucleic acid analysis. Nucleic acid polymer particles of the invention allow polynucleotides to be attached throughout their volumes for higher loading capacities than those achievable solely with surface attachment. In one aspect, nucleic acid polymer particles of the invention comprise polyacrylamide particles with uniform size distributions having low coefficients of variations, which result in reduced particle-to-particle variation in analytical assays. Such particle compositions are used in various amplification reactions to make amplicon libraries from nucleic acid fragment libraries.
-
公开(公告)号：EP3249057A1
公开(公告)日：2017-11-29
申请号：EP17181624.2
申请日：2014-03-13
Applicant: Life Technologies Corporation
Inventor： LIGHT, David , HINZ, Wofgang , CICERO, Ronald , INMAN, Christina , KENNEY, Paul , MASTROIANNI, Alexander , ROZHKOV, Roman , WANG, Yufang , GRAY, Jeremy , GLAZER, Marc , GREMYACHINSKIY, Dmitriy
IPC: C12Q1/68
CPC classification number: C12Q1/6837 , C12Q1/6806 , C12Q1/6834 , C12Q1/6869 , C12Q2523/101 , C12Q2527/119 , C12Q2535/122 , C12Q2547/107 , C12Q2563/159 , C12Q2565/537 , C12Q2523/301 , C12Q2523/32
Abstract: A method of forming a polymer matrix array includes applying an aqueous solution into wells of a well array. The aqueous solution includes polymer precursors. The method further includes applying an immiscible fluid over the well array to isolate the aqueous solution within the wells of the well array and polymerizing the polymer precursors isolated in the wells of the well array to form the polymer matrix array. An apparatus includes a sensor array, a well array corresponding to the sensor array, and an array of polymer matrices disposed in the well array.
Abstract translation: 形成聚合物基质阵列的方法包括将水溶液施加到孔阵列的孔中。 水溶液包含聚合物前体。 该方法进一步包括在井阵列上施加不混溶流体以隔离井阵列的井内的水溶液，并聚合在井阵列的井中分离的聚合物前体以形成聚合物基质阵列。 一种装置包括传感器阵列，对应于传感器阵列的井阵列以及布置在井阵列中的聚合物矩阵的阵列。
-
公开(公告)号：EP4116338A1
公开(公告)日：2023-01-11
申请号：EP22192503.5
申请日：2013-02-08
Applicant: Life Technologies Corporation
Inventor： FONNUM, Geir , MODAHL, Grete , KJUS, Nini , MOLTEBERG, Astrid Evenroed , TRAN, Diem , AASERUD, Jo , GOKMEN, M. Talha , MENCHEN, Steven , FULLER, Carl , ANDRUZZI, Luisa , HINZ, Wolfgang , GREMYACHINSKIY, Dmitriy , LIGHT, David , MASTROIANNI, Alexander , ROSENBLUM, Barnett , KHAN, Shaheer , STOLARCZYK, Craig , SOKOLSKY, Tanya
IPC: C08F2/16 , C08F220/54 , C08F8/12 , C08F222/38 , C12Q1/68 , C09D5/00 , C08F2/20 , C08F2/26 , C08F230/08 , C08F257/02 , C08F220/58 , C08F220/60 , C08F8/34 , C08F130/08 , C07F7/18
Abstract: A method of forming a particle includes, in a disperse phase within an aqueous suspension, polymerizing a plurality of mer units of a hydrophilic monomer having a hydrophobic protection group, thereby forming a polymeric particle including a plurality of the hydrophobic protection groups. The method further includes converting the polymeric particle to a hydrophilic particle.
-
公开(公告)号：EP3164505B1
公开(公告)日：2018-06-27
申请号：EP15745292.1
申请日：2015-07-01
Applicant: Life Technologies Corporation
Inventor： LIGHT, David , CICERO, Ronald L. , WANG, Yufang , MASTROIANNI, Alexander , THWAR, Prasanna Krishnan , GRAY, Jeremy , GLAZER, Marc , LINCECUM, Tommie Lloyd Jr. , ALANJARY, Mohammad , KOSCINSKI, Joseph
IPC: C12Q1/68
CPC classification number: B01J19/0046 , B01J2219/00596 , B01J2219/00677 , C12Q1/6806 , C12Q1/6869 , C12Q2523/32 , C12Q2527/119 , C12Q2535/122 , C12Q2563/149 , C12Q2563/155 , C12Q2565/607 , C12Q2565/629
Abstract: A method of loading beads on a sensor substrate includes applying a suspension including beads to a flow cell defined over a sensor substrate. The sensor substrate includes a plurality of wells. The beads at least partially deposit into the plurality of wells. The method also includes removing liquid from the flow cell, evaporating liquid from the flow cell, for example, by drawing air through the flow cell; and applying a hydrating solution to the flow cell.
-
Patent Agency Ranking16.发明公开
公开(公告)号：EP2971089A1
公开(公告)日：2016-01-20
申请号：EP14716714.2
申请日：2014-03-13
Applicant: Life Technologies Corporation
Inventor： LIGHT, David , HINZ, Wolfgang , CICERO, Ronald , INMAN, Christina , KENNEY, Paul , MASTROIANNI, Alexander , ROZHKOV, Roman , WANG, Yufang , GRAY, Jeremy , GLAZER, Marc , GREMYACHINSKIY, Dmitriy
IPC: C12Q1/68
CPC classification number: C12Q1/6837 , C12Q1/6806 , C12Q1/6834 , C12Q2523/101
Abstract: A method of forming a polymer matrix array includes applying an aqueous solution into wells of a well array. The aqueous solution includes polymer precursors. The method further includes applying an immiscible fluid over the well array to isolate the aqueous solution within the wells of the well array and polymerizing the polymer precursors isolated in the wells of the well array to form the polymer matrix array. An apparatus includes a sensor array, a well array corresponding to the sensor array, and an array of polymer matrices disposed in the well array.
Abstract translation: 形成聚合物基质阵列的方法包括将水溶液施加到阱阵列的孔中。 水溶液包括聚合物前体。 该方法还包括在井阵列上施加不混溶流体以将井阵列中的水溶液隔离并聚合在井阵列的孔中分离的聚合物前体以形成聚合物基质阵列。 一种装置包括传感器阵列，对应于传感器阵列的阱阵列和布置在阱阵列中的聚合物阵列阵列。
-
公开(公告)号：EP3249057B1
公开(公告)日：2019-05-01
申请号：EP17181624.2
申请日：2014-03-13
Applicant: Life Technologies Corporation
Inventor： LIGHT, David , HINZ, Wofgang , CICERO, Ronald , INMAN, Christina , KENNEY, Paul , MASTROIANNI, Alexander , ROZHKOV, Roman , WANG, Yufang , GRAY, Jeremy , GLAZER, Marc , GREMYACHINSKIY, Dmitriy
IPC: C12Q1/68
-
18.发明授权
公开(公告)号：EP2588838B1
公开(公告)日：2018-03-21
申请号：EP11834771.5
申请日：2011-06-28
Applicant: Life Technologies Corporation
Inventor： LIGHT, David , HINZ, Wolfgang , REARICK, Todd , BALL, James
IPC: G01N27/414 , B01L3/00
CPC classification number: B01L3/502761 , B01L2200/0668 , B01L2300/0636 , B01L2300/0877 , B01L2400/0415 , G01N27/4145
Abstract: The disclosure relates to novel particle compositions and methods of making said compositions having applications in nucleic acid analysis, as well as apparatuses and systems for the same.
-
公开(公告)号：EP2435461B1
公开(公告)日：2017-08-09
申请号：EP10780934.5
申请日：2010-05-27
Applicant: Life Technologies Corporation
Inventor： HINZ, Wolfgang , LEAMON, John H. , LIGHT, David , ROTHBERG, Jonathan M.
CPC classification number: C12N15/1093 , C12Q1/6806 , C12Q1/6834 , C12Q1/6853 , C12Q2535/122 , C12Q2563/155 , C12Q2563/159 , C12Q2565/607 , C12Q2565/537 , C12Q2565/629
-
公开(公告)号：EP2971089B1
公开(公告)日：2017-07-19
申请号：EP14716714.2
申请日：2014-03-13
Applicant: Life Technologies Corporation
Inventor： LIGHT, David , HINZ, Wolfgang , CICERO, Ronald , INMAN, Christina , KENNEY, Paul , MASTROIANNI, Alexander , ROZHKOV, Roman , WANG, Yufang , GRAY, Jeremy , GLAZER, Marc , GREMYACHINSKIY, Dmitriy
IPC: C12Q1/68
CPC classification number: C12Q1/6837 , C12Q1/6806 , C12Q1/6834 , C12Q2523/101
-
-
-
-
-
-
-
-
-
Search Results
23
records
(took 0.028 seconds)
