公开(公告)号：US10143990B2

公开(公告)日：2018-12-04

申请号：US15203582

申请日：2016-07-06

Applicant: LIFE TECHNOLOGIES CORPORATION

Inventor： Alexander Mastroianni ,  Scott C. Benson ,  Steven M. Menchen ,  John Scott

IPC: B01J19/00 ,  C12Q1/6806 ,  C12Q1/6837 ,  C12Q1/6869

Abstract: A method of preparing a discrete polymer network array include mixing a plurality of nucleic acid polymer networks with a plurality of color-activated polymer networks to form a dispersion, applying the dispersion to an array of wells, the nucleic acid polymer networks selectively depositing into wells of the array of wells, and rinsing the array of wells to selectively remove the plurality of color-activated polymer networks.

公开(公告)号：US20180127811A1

公开(公告)日：2018-05-10

申请号：US15707157

申请日：2017-09-18

Applicant: Life Technologies Corporation

Inventor： Scott C. Benson ,  Cinna Monighetti ,  Sandy M. Koepf

IPC: C12Q1/6818 ,  C12Q1/6844 ,  C09B15/00 ,  C12Q1/6851

CPC classification number: C12Q1/6844 ,  C09B15/00 ,  C12Q1/6818 ,  C12Q1/6851 ,  C12Q2527/125 ,  C12Q2545/101 ,  C12Q2561/113 ,  C12Q2563/107

Abstract: According to the present teachings, methods and compositions are provided that utilize at least one reference dye of formula (I): In some embodiments, a method comprises measuring a detection signal of a reporter dye and at least one reference dye of formula (I). In some embodiments, a composition comprises a reference dye of formula (1), a buffer, a selection of nucleotides and a protein.

公开(公告)号：US09790544B2

公开(公告)日：2017-10-17

申请号：US15066248

申请日：2016-03-10

Applicant: LIFE TECHNOLOGIES CORPORATION

Inventor： Scott C. Benson ,  Cinna Monighetti ,  Sandy M. Koepf

IPC: C12Q1/68 ,  C12P19/34 ,  C09B15/00

CPC classification number: C12Q1/6818 ,  C09B15/00 ,  C12Q1/6844 ,  C12Q1/6851 ,  C12Q2527/125 ,  C12Q2545/101 ,  C12Q2561/113 ,  C12Q2563/107

Abstract: According to the present teachings, methods and compositions are provided that utilize at least one reference dye of formula (I): In some embodiments, a method comprises measuring a detection signal of a reporter dye and at least one reference dye of formula (I). In some embodiments, a composition comprises a reference dye of formula (1), a buffer, a selection of nucleotides and a protein.

公开(公告)号：US09315859B2

公开(公告)日：2016-04-19

申请号：US14071552

申请日：2013-11-04

Applicant: LIFE TECHNOLOGIES CORPORATION

Inventor： Scott C. Benson ,  Cinna Monighetti ,  Sandy M. Koepf

IPC: C12Q1/68 ,  C12P19/34 ,  C09B15/00 ,  C07H21/02 ,  C07H21/04

CPC classification number: C12Q1/6818 ,  C09B15/00 ,  C12Q1/6844 ,  C12Q1/6851 ,  C12Q2527/125 ,  C12Q2545/101 ,  C12Q2561/113 ,  C12Q2563/107

Abstract: According to the present teachings, methods and compositions are provided that utilize at least one reference dye of formula (I): In some embodiments, a method comprises measuring a detection signal of a reporter dye and at least one reference dye of formula (I). In some embodiments, a composition comprises a reference dye of formula (1), a buffer, a selection of nucleotides and a protein.

Abstract translation: 根据本教导，提供利用至少一种式（I）的参考染料的方法和组合物：在一些实施方案中，一种方法包括测量报道染料和至少一种式（I）的参考染料的检测信号， 。 在一些实施方案中，组合物包含式（1）的参考染料，缓冲液，核苷酸和蛋白质的选择。