公开(公告)号：AU5332300A

公开(公告)日：2000-12-28

申请号：AU5332300

申请日：2000-06-09

Applicant: MEDISPECTRA INC

Inventor： NORDSTROM ROBERT ,  BEE DAVID ,  MODELL MARK ,  HED ZE EV ,  KWO JENNIE ,  EMANS MATTHEW

IPC: A61B1/00 ,  A61B19/00

公开(公告)号：CA2359576A1

公开(公告)日：2000-07-20

申请号：CA2359576

申请日：2000-01-11

Applicant: MEDISPECTRA INC

Inventor： MODELL MARK ,  HED ZE EV A ,  EMANS MATTHEW ,  LIPSON DAVID ,  BEE DAVID ,  NORDSTROM ROBERT ,  KWO JENNIE

IPC: G01N21/64 ,  A61B1/00 ,  A61B5/00 ,  G01N21/47

Abstract: Methods and apparatus are provided for determining a characteristic of a sample of a material by the interaction of electromagnetic radiation with th e sample. The apparatus includes an optical assembly and a protective barrier. The optical assembly sequentially illuminates a plurality of volume elements in the sample with an intensity distribution in the sample that drops off substantially monotonically from a first region in a first optical path and collects electromagnetic radiation emanating from each of the volume element s. The optical assembly collects the electromagnetic radiation emanating from each of the volume elements with a collected distribution that drops off substantially monotonically from a second region in a second optical path. T he first and second regions at least partially overlap in each of the volume elements. The optical assembly can be configured as a probe, to be directed to the evaluation of a sample of a biological material. A protective barrier ca n be disposed between the optical assembly and a body tissue, to prevent contamination of the optical assembly by said body tissue.

公开(公告)号：AU2003254731A1

公开(公告)日：2003-11-13

申请号：AU2003254731

申请日：2003-10-15

Applicant: MEDISPECTRA INC

Inventor： HED ZE EV A ,  MODELL MARK ,  LIPSON DAVID ,  EMANS MATTHEW ,  KWO JENNIE ,  NORDSTROM ROBERT ,  BEE DAVID

IPC: G01N21/64 ,  A61B1/00 ,  A61B5/00 ,  G01N21/47

公开(公告)号：CA2375168A1

公开(公告)日：2000-12-14

申请号：CA2375168

申请日：2000-06-09

Applicant: MEDISPECTRA INC

Inventor： EMANS MATTHEW ,  KWO JENNIE ,  HED ZE EV ,  MODELL MARK ,  BEE DAVID ,  NORDSTROM ROBERT

IPC: A61B1/00 ,  A61B19/00 ,  A61B5/00

Abstract: The present invention recognizes that optical probes function both as medica l access devices and as instruments which collect complex optical data. The invention provides an optical probe accessory device which can access lumina l spaces within the body of a patient without sacrificing the quality of optic al data obtained. The accessory device further comprises either, singly, or in combination, selectable features or options which optimize light transmissio n, maximize patient comfort, and provide single-use capabilities.

公开(公告)号：AU2723600A

公开(公告)日：2000-08-01

申请号：AU2723600

申请日：2000-01-11

Applicant: MEDISPECTRA INC

Inventor： MODELL MARK ,  HED ZE EV A ,  BEE DAVID ,  NORDSTROM ROBERT ,  KWO JENNIE ,  EMANS MATTHEW ,  LIPSON DAVID

IPC: G01N21/64 ,  A61B1/00 ,  A61B5/00 ,  G01N21/47

公开(公告)号：AU2715300A

公开(公告)日：2000-07-12

申请号：AU2715300

申请日：1999-12-22

Applicant: MEDISPECTRA INC

Inventor： NORDSTROM ROBERT ,  MODELL MARK ,  ZELENCHUK ALEXANDER

IPC: G01N21/64 ,  A61B1/04 ,  A61B5/00 ,  A61B6/00 ,  A61B10/00 ,  G01N20060101 ,  G01N21/17 ,  G01N21/27 ,  G01N21/33 ,  G01N21/47

Abstract: The present invention relates to systems and methods for examining a sample using a substantially monostatic, substantially confocal optical system comprising transmitting optics that focus an illuminating light upon the sample and receiving optics that collect light emitted from the sample following illumination thereof. In certain embodiments, the receiving optics may be arranged circumferentially around the light path traversed by the illuminating light. In certain embodiments, video apparatus may be included to produce images or to align the system in proximity to the target tissue. The systems and methods of the present invention may be directed towards the examination of a body tissue to provide a medical diagnosis.

公开(公告)号：CA2356195A1

公开(公告)日：2000-06-29

申请号：CA2356195

申请日：1999-12-23

Applicant: MEDISPECTRA INC

Inventor： MODELL MARK ,  NORDSTROM ROBERT

IPC: G01N21/64 ,  A61B5/00 ,  A61B10/00 ,  G01N21/27 ,  G01N21/35

Abstract: A method and a system is provided for discriminating between healthy cervica l tissue and pathologic cervical tissue based on the fluorescence response of the tissue to laser excitation (LIF) and the backscatter response to illumination by white light (in the spectral range of 360 to 750 nm). Combining LIF and white light responses, as well as evaluating a spatial correlation between proximate cervical tissue sites in conjunction with a statistically significant "distance" algorithm, such as the Mahalanobis distance between data sets, can improve the discrimination between normal an d abnormal tissue. The results may be displayed in the form of a map of the cervix representing the suspected pathology.