公开(公告)号：JP2001026527A

公开(公告)日：2001-01-30

申请号：JP2000164445

申请日：2000-06-01

Applicant: OREAL

Inventor： LANG GERARD ,  LAGRANGE ALAIN

IPC: C12N9/02 ,  A61K8/00 ,  A61K8/33 ,  A61K8/40 ,  A61K8/41 ,  A61K8/46 ,  A61K8/49 ,  A61K8/66 ,  A61K8/97 ,  A61K8/99 ,  A61Q5/10 ,  C07D249/18 ,  D06P3/08 ,  A61K7/13

Abstract: PROBLEM TO BE SOLVED: To obtain the subject composition which can non-selectively dye keratin fibers in a strong color exhibiting good durability against various damage factors without causing the large deterioration of the keratin fibers, by compounding a specific oxidizing base, a specified enzyme and a specific enzyme mediator. SOLUTION: This composition for oxidatively dyeing keratin fibers is prepared by dissolving (A) at least one oxidizing base selected from a para- phenylenediamine compound of formula I (R1, R2, R4 are each H, an alkyl, or the like; R3 is H, a halogen, or the like) (for example, para-phenylenediamine), a double base [for example, N,N'-bis(β-hydroxyethyl)-N,N'-bis(4'- aminophenyl)-1,3-diaminopropanol], a para-aminophenol compound of formula II (R5, R6 are each H, a halogen, or the like) (for example, para-aminophenol), and a heterocyclic base compound (for example, a pyridine derivative), (B) a four electron oxide reductase type enzyme (for example, laccase), and (C) an enzyme mediator (for example, hydroxylamine) capable of increasing the activity of the enzyme in a medium suitable for the dyeing.

公开(公告)号：JP2000086472A

公开(公告)日：2000-03-28

申请号：JP19681599

申请日：1999-07-09

Applicant: OREAL

Inventor： LANG GERARD ,  COTTERET JEAN

IPC: A61K8/00 ,  A45D20060101 ,  A45D19/00 ,  A61K20060101 ,  A61K8/33 ,  A61K8/35 ,  A61K8/36 ,  A61K8/37 ,  A61K8/41 ,  A61K8/49 ,  A61K8/58 ,  A61K8/73 ,  A61K8/87 ,  A61Q5/06 ,  A61Q5/10 ,  C07D207/00 ,  C09B44/00 ,  C09B44/10 ,  C09B44/12 ,  C09B44/14 ,  C09B44/16 ,  C09B44/18 ,  C09B44/20 ,  C09B67/42 ,  D06P1/08 ,  D06P3/04 ,  D06P3/08 ,  A61K7/13

Abstract: PROBLEM TO BE SOLVED: To obtain a composition capable of applying stronger coloration with scarcely any selectivity and useful for dyeing karatinous fibers such as human hair by including a specific direct dye and a specified thickening polymer in a medium. SOLUTION: This composition is obtained by including (B) a cationic direct dye selected from a compound represented by formula I D is N or the like; R1 and R2 are each H or the like; R3 and R3' are each cyano or the like; X- is an anion such as a chloride; A is a structure represented by formula II [R4 is an (OH-substituted) 1-4C alkyl or the like] or the like, with the proviso that R1 and R2 are not simultaneously H when D is CH; A is formula II or the like; R3 is other than an alkoxy}, a compound represented by formula III [R6 is a 1-4C alkyl or the like; R7 is H or the like; R8 and R9 are each a halogen or the like such as F; B is a structure represented by formula IV (R10 is a 1-4C alkyl) or the like] or the like and (C) a thickening polymer selected from a nonionic amphiphilic polymer containing a unit having an aliphatic chain and a hydrophilic unit, an anionic amphiphilic polymer containing a unit having an aliphatic chain and a hydrophilic unit or the like in (A) a medium.

公开(公告)号：JP2000007542A

公开(公告)日：2000-01-11

申请号：JP14501499

申请日：1999-05-25

Applicant: OREAL

Inventor： LANG GERARD ,  COTTERET JEAN

IPC: C07D277/82 ,  A61K8/00 ,  A61K8/33 ,  A61K8/35 ,  A61K8/41 ,  A61K8/49 ,  A61K8/84 ,  A61K8/88 ,  A61Q5/06 ,  A61Q5/10 ,  C07D213/76 ,  C07D213/89 ,  C07D235/30 ,  C07D401/12 ,  C07D413/12 ,  C07D417/12 ,  A61K7/13

Abstract: PROBLEM TO BE SOLVED: To obtain a dyeing composition for keratin fiber such as human hair exhibiting resistance to various attacking factors of hair by including a specific cationic direct dye and a specific polymer in a medium. SOLUTION: The objective dyeing composition is produced by incorporating (A) a medium with (B) a cationic direct dye of formula A-N=N-B A is a group of formula I [R1 is a (substituted) phenyl or a 1-4C alkyl; R2 is a 1-4C alkyl or phenyl; R3 and R4 are each a 1-4C alkyl, phenyl or the like; X is an anion] or the like; B is a group of formula II (R8 is a halogen such as Cl, H or the like; R9 is a halogen such as Cl, a 1-4C alkyl or the like; R10 is H, OH or the like) or the like} and (C) a cationic or ampholytic directly attachable polymer such as poly-quaternary ammonium polymer selected from a polymer composed of the repeating unit of formula III, a polymer composed of the repeating unit of formula IV and a polymer composed of the repeating unit of formula V [(p) is about 1-6; D is 0 or (CH2)r-CO ((r) is 4 or 7)].

公开(公告)号：JPH11292830A

公开(公告)日：1999-10-26

申请号：JP32792698

申请日：1998-11-18

Applicant: OREAL

Inventor： JUNINO ALEX ,  GENET ALAIN ,  LANG GERARD

IPC: A61K8/00 ,  A61K8/33 ,  A61K8/41 ,  A61K8/49 ,  A61Q5/10 ,  B01J27/24 ,  C07B61/00 ,  C07C67/00 ,  C07C209/00 ,  C07C209/10 ,  C07C209/36 ,  C07C209/76 ,  C07C211/49 ,  C07C211/51 ,  C07C211/52 ,  C07C211/53 ,  C07C213/02 ,  C07C215/14 ,  C07C215/16 ,  C07C215/18 ,  C09B67/42 ,  D06P3/08 ,  A61K7/13

Abstract: PROBLEM TO BE SOLVED: To provide a method for producing an aniline compound in high yield by condensing a dihalogenated hydrocarbon with an N-substituted aniline in a polar solvent in the presence of a basic compound, nitrosating the obtained compound, and reducing the nitrosated compound. SOLUTION: (A) A dihalogenated hydrocarbon of the formula X-CH2 -Y-CH2 -X Y is (CH2 )n [(n) is 0-8] or the like; X is a halogen} is condensed with (B) an N-substituted aniline of formula I (R is a 1-4C alkyl, a 2-4C hydroxyalkyl or the like; R1 is H, a halogen or the like) in a polar solvent (e.g. water) in the presence of a basic compound to provide (C) a compound of formula II, and the compound of formula II is nitrosated, preferably by the action of a mixture of sodium nitrite with hydrochloric acid in water at

公开(公告)号：FR2648131A1

公开(公告)日：1990-12-14

申请号：FR8907805

申请日：1989-06-13

Applicant: OREAL ,  OREAL

Inventor： MAIGNAN JEAN ,  JEAN MAIGNAN ,  MALLE GERARD ,  GERARD MALLE ,  DEFLANDRE ANDRE ,  ANDRE DEFLANDRE ,  LANG GERARD ,  GERARD LANG

IPC: A61K8/30 ,  A61K8/33 ,  A61K8/34 ,  A61K8/41 ,  A61K8/92 ,  A61K31/05 ,  A61K31/045 ,  A61K31/085 ,  A61K31/12 ,  A61K31/135 ,  A61K31/19 ,  A61K31/215 ,  A61K47/10 ,  A61P17/00 ,  A61P29/00 ,  A61P35/00 ,  A61P37/08 ,  A61Q17/00 ,  C07C37/06 ,  C07C39/08 ,  C07C39/17 ,  C07C41/26 ,  C07C41/30 ,  C07C43/21 ,  C07C43/23 ,  C07C45/27 ,  C07C45/46 ,  C07C45/68 ,  C07C49/83 ,  C07C49/84 ,  C07C50/10 ,  C07C65/17 ,  C07C65/26 ,  C09K15/08

Abstract: Dérivés de tétrahydro-5,6,7,8 naphtalénol-1. Ces dérivés répondent à la formule générale suivante : (CF DESSIN DANS BOPI) dans laquelle : R1 , R2 , R3 , R4 , R5 et R6 représentent un atome d'hydrogène ou un radical alkyle inférieur, R représente un atome d'hydrogène, un radical alkyle en C1 -C1 8 , un radical alkyle en C2 -C1 8 substitué par un ou plusieurs hydroxyle(s), un radical alkényle en C3 -C1 8 , un radical acyle en C2 -C1 8 , un radical benzyle, un radical benzoyle, un radical carboxyle et les sels carboxyliques d'un métal alcalin ou alcalino-terreux ou d'une amine organique. Ces dérivés trouvent une application en tant qu'agents antioxydants dans des compositions cosmétiques et dans des compositions pharmaceutiques pour le traitement préventif d'inflammations et allergies cutanées ou de certaines formes de cancers.

公开(公告)号：FR2607700A1

公开(公告)日：1988-06-10

申请号：FR8717001

申请日：1987-12-07

Applicant: OREAL ,  OREAL

Inventor： FORESTIER SERGE ,  SERGE FORESTIER ,  DEFLANDRE ANDRE ,  ANDRE DEFLANDRE ,  LANG GERARD ,  GERARD LANG ,  GROLLIER JEAN-FRANCOIS ,  JEAN-FRANCOIS GROLLIER ,  COTTERET JEAN ,  JEAN COTTERET

IPC: A61K20060101 ,  A61K8/33 ,  A61K8/00 ,  A61K8/34 ,  A61K8/35 ,  A61K8/36 ,  A61K8/37 ,  A61K8/92 ,  A61K9/02 ,  A61K9/06 ,  A61K9/08 ,  A61K9/10 ,  A61K9/107 ,  A61K9/12 ,  A61Q17/04 ,  C07C45/86 ,  C07C49/683 ,  C07C49/84 ,  A61K7/42

Abstract: L'INVENTION CONCERNE UNE COMPOSITION COSMETIQUE FILTRANTE PHOTOSTABLE POUR LA PROTECTION DE L'EPIDERME HUMAIN CONTRE LES RAYONS UV, COMPRENANT, DANS UN SUPPORT COSMETIQUEMENT ACCEPTABLE CONTENANT AU MOINS UNE PHASE GRASSE, 1 A 3 EN POIDS DE 4-(1,1-DIMETHYLETHYL)-4-METHOXY DIBENZOYLMETHANE ET AU MOINS 4,5 EN POIDS DE P-METHYLBENZYLIDENE CAMPHRE, LE RAPPORT EN POIDS DU P-METHYLBENZYLIDENE CAMPHRE AU 4-(1,1-DIMETHYLETHYL)-4-METHOXYDIBENZOYLMETHANE ETANT SUPERIEUR OU EGALE A 3. ELLE CONCERNE AUSSI UN PROCEDE DE PROTECTION DE LA PEAU CONTRE LE RAYONNEMENT UV AINSI QU'UN PROCEDE DE STABILISATION DU 4-(1,1-DIMETHYLETHYL)-4-METHOXY DIBENZOYLMETHANE VIS-A-VIS DU RAYONNEMENT UV.

公开(公告)号：FR2636062A1

公开(公告)日：1990-03-09

申请号：FR8811634

申请日：1988-09-06

Applicant: OREAL ,  OREAL

Inventor： JUNINO ALEX ,  ALEX JUNINO ,  GENET ALAIN ,  ALAIN GENET ,  LANG GERARD ,  GERARD LANG

IPC: A61K8/33 ,  A61K8/41 ,  A61K8/49 ,  A61Q5/10 ,  A61K8/00 ,  B01J27/24 ,  C07B61/00 ,  C07C67/00 ,  C07C209/00 ,  C07C209/10 ,  C07C209/36 ,  C07C209/76 ,  C07C211/49 ,  C07C211/51 ,  C07C211/52 ,  C07C211/53 ,  C07C213/02 ,  C07C215/14 ,  C07C215/16 ,  C07C215/18 ,  C09B67/42 ,  D06P3/08

Abstract: L'invention est relative à un procédé de préparation d'un composé répondant à la formule : (CF DESSIN DANS BOPI) dans laquelle R est alkyle, hydroxyalkyle ou amino alkyle; R1 est hydrogène, halogène ou alkyle; Y désigne -$SL (CH2 -$SL )n avec n ayant une valeur de 0 à 8, ou bien -$SL (CH2 -$SL )n , CHOH-$SL (CH2 -$SL )n , dans laquelle n' a une valeur de 0 à 4, consistant à (i) condenser un hydrocarbure dihalogéné sur une aniline N-substituée; (ii) à procéder à la nitrosation du composé en résultant; (iii) et à procéder à la réduction du composé ainsi obtenu et au composé nouveau constitué par le N,N'-bis-(beta-hydroxyéthyl)N,N'-bis-(amino-4'phényl) diamino-1,3 propanol-2 et aux intermédiaires nouveaux utilisés.

公开(公告)号：DE69920401T3

公开(公告)日：2015-10-22

申请号：DE69920401

申请日：1999-07-28

Applicant: OREAL

Inventor： LANG GERARD ,  COTTERET JEAN

IPC: A61K8/00 ,  A61K20060101 ,  A61K8/23 ,  A61K8/35 ,  A61K8/49 ,  A61K8/72 ,  A61K8/898 ,  A61Q5/06 ,  A61Q5/10

公开(公告)号：DE69925570T3

公开(公告)日：2010-08-12

申请号：DE69925570

申请日：1999-07-29

Applicant: OREAL

Inventor： RONDEAU CHRISTINE ,  LANG GERARD ,  COTTERET JEAN

IPC: A61K8/00 ,  A61Q5/06 ,  A61K20060101 ,  A61K8/35 ,  A61K8/41 ,  A61K8/49 ,  A61K8/89 ,  A61K8/891 ,  A61K8/894 ,  A61K8/898 ,  A61Q5/10 ,  C08L83/04 ,  C08L83/08 ,  C09B23/00 ,  C09B27/00 ,  D06P1/41 ,  D06P1/42 ,  D06P1/52 ,  D06P3/24

公开(公告)号：DE69823700T3

公开(公告)日：2009-08-27

申请号：DE69823700

申请日：1998-12-22

Applicant: OREAL

Inventor： LANG GERARD ,  COTTERET JEAN

IPC: A61K8/00 ,  A61K8/66 ,  A61K8/33 ,  A61K8/41 ,  A61K8/49 ,  A61Q5/10

Abstract: The invention concerns a ready-to-use composition for oxidation dyeing of keratinous fibres, and in particular human keratinous fibres such as hair comprising, in a medium suitable for dyeing, 3-methyl 4-amino phenol as oxidation base, and at least an enzyme such as laccase, as well as the dyeing method using said composition.