公开(公告)号：JP2003119164A

公开(公告)日：2003-04-23

申请号：JP2002209684

申请日：2002-07-18

Applicant: OREAL

Inventor： RICHARD HERVE

IPC: C07D453/02 ,  A61K8/00 ,  A61K8/04 ,  A61K8/29 ,  A61K8/33 ,  A61K8/35 ,  A61K8/37 ,  A61K8/46 ,  A61K8/49 ,  A61K8/58 ,  A61Q1/00 ,  A61Q5/00 ,  A61Q17/04 ,  C07C49/67 ,  C07C49/675 ,  C07C311/13 ,  C07F7/08 ,  C09K3/00 ,  A61K7/42

Abstract: PROBLEM TO BE SOLVED: To obtain an insoluble organic compound for shielding UV irradiation. SOLUTION: An insoluble organic compound for shielding UV irradiation, having at least one allyl vinyl ketone group and being in a shape of fine particle with 10 nm-5 μm particle size and a material sensitive to the UV irradiation are obtained and application of those as an agent for shielding the UV irradiation in order to protect the skin or hair or control skin color is provided. This organic UV shielding agent is obtained by grinding the insoluble organic compound or the material sensitive to the UV irradiation in the presence of one or more suitable surfactants. The term 'allyl vinylene ketone' includes all allyl vinylene derivatives containing a carbonyl group at α position to a double bond but free from amide group.

公开(公告)号：JPH10147589A

公开(公告)日：1998-06-02

申请号：JP29754197

申请日：1997-10-29

Applicant: OREAL

Inventor： LEDUC MADELEINE ,  RICHARD HERVE ,  LAGRANGE ALAIN

IPC: A61K8/00 ,  A61K8/35 ,  A61K8/40 ,  A61K8/58 ,  A61K8/89 ,  A61K8/893 ,  A61K8/895 ,  A61K8/896 ,  A61K8/898 ,  A61Q5/06 ,  A61Q5/10 ,  C07F7/08 ,  C07F7/10 ,  C07F7/18 ,  C07F7/21 ,  C08G77/04 ,  C08G77/14 ,  C08G77/26 ,  C08L83/06 ,  C08L83/08 ,  A61K7/13

Abstract: PROBLEM TO BE SOLVED: To obtain the subject new compound, comprising a specific silicon compound containing a quinone or an azo type chromophore, capable of manifesting an excellent nontoxic level without using an oxidizing agent and useful as a dyeing composition, etc., for human keratinous fiber such as hair. SOLUTION: This new silicone compound is represented by formula I [R is a 1-10C alkyl, phenyl or 3,3,3-trifluoropropyl and at least 80% of groups R are methyl; B is R or A A is a chromophore such as a quinone represented by formula II [R4 is a 1-6C alkyl, OH, a 1-4C alkoxy, etc.; (m) is 0-2; D is SO2 NH, CONH, O, etc., W is an alkylene, etc.; (n) is 2, etc.] or an azo type represented by formula III}, (r) is 0-50; (s) is 0-20], formula IV [(t) is 0-10; (u) is 1-6; (t+u) is >=3] and formula V and is useful as a direct dye, etc., for dyeing human keratinous fiber. The compound is obtained by carrying out the hydrosilylating reaction of a compound in which the group A is H with an unsaturated compound having the quinone or azo type chromophore.

公开(公告)号：JPH05504572A

公开(公告)日：1993-07-15

申请号：JP50496791

申请日：1991-02-13

Applicant: OREAL

Inventor： DEFLANDRE ANDRE ,  DUBOIS MICHEL ,  FORESTIER SERGE ,  RICHARD HERVE

IPC: A61K8/00 ,  A61K20060101 ,  A61K8/04 ,  A61K8/34 ,  A61K8/35 ,  A61K8/36 ,  A61K8/37 ,  A61K8/40 ,  A61K8/92 ,  A61K31/12 ,  A61K31/19 ,  A61Q17/04 ,  C07C49/784 ,  C07C69/618

公开(公告)号：JPH10120536A

公开(公告)日：1998-05-12

申请号：JP28093497

申请日：1997-10-14

Applicant: OREAL

Inventor： RICHARD HERVE ,  LAGRANGE ALAIN ,  DUBIEF CLAUDE ,  BRAIDA VALERIO DAMARYS

IPC: A61K8/00 ,  A61K8/49 ,  A61K8/58 ,  A61K8/89 ,  A61Q5/00 ,  A61Q5/02 ,  A61Q17/04 ,  C08G77/14 ,  C08G77/26 ,  C08G77/34 ,  C08G77/38 ,  C08L83/08 ,  A61K7/06 ,  A61K7/44

Abstract: PROBLEM TO BE SOLVED: To obtain a composition for cosmetic or skin treatment capable of protecting from detection of colored hair by sunlight by including a specific organosilixane as an effective ingredient into the composition. SOLUTION: This composition contains at least 0.001wt.% preferably 1-10wt.% (based on the total composition) of an organosiloxane having at least one UV- absorbing group. As the organosiloxane, a compound containing at least one unit expressed y formula I [R' is a 1-30C hydrocarbon, trimethylsiloxane, etc.; (a) is 1 or 2; T=-E-U (E is a divalent aliphatic hydrcarbon; U is the residue of a molecule which shields UV irradiations)] in the molecule, especially benzotriazolesilicone of formula II is preferable.

公开(公告)号：WO2012119861A3

公开(公告)日：2013-08-22

申请号：PCT/EP2012053067

申请日：2012-02-23

Applicant: OREAL ,  RICHARD HERVE ,  MULLER BENOIT

Inventor： RICHARD HERVE ,  MULLER BENOIT

IPC: A61K8/37 ,  A61K8/35 ,  A61K8/49 ,  A61Q17/04

CPC classification number: A61K8/37 ,  A61K2800/49 ,  A61Q17/04 ,  C07C69/40

Abstract: The present invention relates to the use of at least one 2-methylsuccinic acid diester derivative of formula (I), in a composition comprising, in a cosmetically acceptable medium, at least one liquid fatty phase and at least one lipophilic active agent, for dissolving the said active agent in the said liquid fatty phase and/or for improving the solubility of the said active agent in the said solid fatty phase. The present invention relates especially to a composition comprising, in a cosmetically acceptable medium, at least one liquid fatty phase, characterized in that it contains at least one 2-methylsuccinic acid ester derivative of formula (I) and at least one lipophilic active agent.

Abstract translation: 本发明涉及至少一种式（I）的2-甲基琥珀酸二酯衍生物在组合物中的用途，所述组合物在化妆品可接受的介质中包含至少一种液体脂肪相和至少一种亲脂性活性剂，用于溶解 所述活性剂在所述液体脂肪相中和/或用于改善所述活性剂在所述固体脂肪相中的溶解度。 本发明特别涉及在化妆品可接受的介质中包含至少一种液体脂肪相的组合物，其特征在于其含有至少一种式（I）的2-甲基琥珀酸酯衍生物和至少一种亲脂性活性剂。

公开(公告)号：WO2013011094A4

公开(公告)日：2013-07-11

申请号：PCT/EP2012064195

申请日：2012-07-19

Applicant: OREAL ,  RICHARD HERVE ,  MARAT XAVIER ,  L ALLORET FLORENCE ,  CANDAU DIDIER ,  SONGEUR-GENEY JULIE ,  GRUMELARD JULIE ,  WINKLER BARBARA ,  HUGLIN DIETMAR

Inventor： RICHARD HERVE ,  MARAT XAVIER ,  L ALLORET FLORENCE ,  CANDAU DIDIER ,  SONGEUR-GENEY JULIE ,  GRUMELARD JULIE ,  WINKLER BARBARA ,  HUGLIN DIETMAR

IPC: A61K8/41 ,  A61K8/42 ,  A61K8/49 ,  A61Q17/04

CPC classification number: A61K8/44 ,  A61K8/347 ,  A61K8/41 ,  A61K8/42 ,  A61K8/49 ,  A61K8/4926 ,  A61K8/4973 ,  A61Q17/04

Abstract: The present invention relates to a cosmetic and/or dermatologigal composition comprising in a physiologically acceptable medium at least one merocyanine derivative of formula (1) or (2) and/or its E,E-, E,Z- or Z,Z-geometrical isomer forms: comprising specific polar groups consisting of hydroxyl- and ether-functionalities. Another object of the present invention relates to a cosmetic process for controlling and/or improving the darkening of the skin under exposure to UV radiation and the homogeneity of the colour of the complexion which comprises the application onto the skin of a cosmetic composition as above defined. Another object of the present invention relates to a cosmetic process for protecting the keratinic materials and particularly the skin against photo-ageing which comprises the application onto the keratinic material of a cosmetic composition as above defined.

Abstract translation: （1）或（2）的部花青衍生物和/或其E，E-，E，Z-或Z，Z- 几何异构体形式：包含由羟基官能团和醚官能团组成的特定极性基团。 本发明的另一个目的涉及一种用于在暴露于UV辐射下控制和/或改善皮肤变黑的化妆方法和该肤色的均匀性，该方法包括将上述定义的化妆品组合物施用到皮肤上 。 本发明的另一个目的涉及一种用于保护角蛋白材料特别是皮肤免受光老化的美容方法，其包括将如上所定义的化妆品组合物施用到角蛋白材料上。

公开(公告)号：WO2013011094A3

公开(公告)日：2013-06-06

申请号：PCT/EP2012064195

申请日：2012-07-19

Applicant: OREAL ,  RICHARD HERVE ,  MARAT XAVIER ,  L ALLORET FLORENCE ,  CANDAU DIDIER ,  SONGEUR-GENEY JULIE ,  GRUMELARD JULIE ,  WINKLER BARBARA ,  HUGLIN DIETMAR

Inventor： RICHARD HERVE ,  MARAT XAVIER ,  L ALLORET FLORENCE ,  CANDAU DIDIER ,  SONGEUR-GENEY JULIE ,  GRUMELARD JULIE ,  WINKLER BARBARA ,  HUGLIN DIETMAR

IPC: A61K8/41 ,  A61K8/42 ,  A61K8/49 ,  A61Q17/04

CPC classification number: A61K8/44 ,  A61K8/347 ,  A61K8/41 ,  A61K8/42 ,  A61K8/49 ,  A61K8/4926 ,  A61K8/4973 ,  A61Q17/04

Abstract: The present invention relates to a cosmetic and/or dermatologigal composition comprising in a physiologically acceptable medium at least one merocyanine derivative of formula (1) or (2) and/or its E,E-, E,Z- or Z,Z-geometrical isomer forms: comprising specific polar groups consisting of hydroxyl- and ether-functionalities. Another object of the present invention relates to a cosmetic process for controlling and/or improving the darkening of the skin under exposure to UV radiation and the homogeneity of the colour of the complexion which comprises the application onto the skin of a cosmetic composition as above defined. Another object of the present invention relates to a cosmetic process for protecting the keratinic materials and particularly the skin against photo-ageing which comprises the application onto the keratinic material of a cosmetic composition as above defined.

Abstract translation: 本发明涉及化妆品和/或皮肤病学组合物，其包含在生理学上可接受的培养基中，至少一种式（1）或（2）的部花青衍生物和/或其E，E-，E，Z-或Z，Z- 几何异构体形式：包括由羟基和醚官能团组成的特定极性基团。 本发明的另一个目的涉及一种用于控制和/或改善在暴露于紫外线辐射下的皮肤变暗的化妆方法和肤色的均匀性，其包括如上所述在化妆品组合物的皮肤上施用 。 本发明的另一个目的涉及一种用于保护角质化材料，特别是皮肤抵抗光老化的美容方法，其包括将上述应用于上述化妆品组合物的角蛋白材料。

公开(公告)号：JP2003095909A

公开(公告)日：2003-04-03

申请号：JP2002179681

申请日：2002-06-20

Applicant: OREAL

Inventor： RICHARD HERVE ,  LUPPI BERNADETTE

IPC: A61K8/00 ,  A61K8/33 ,  A61K8/35 ,  A61K8/42 ,  A61K8/46 ,  A61K8/49 ,  A61K8/58 ,  A61K8/89 ,  A61K8/891 ,  A61P17/16 ,  A61Q1/00 ,  A61Q1/02 ,  A61Q1/04 ,  A61Q1/10 ,  A61Q1/12 ,  A61Q5/00 ,  A61Q5/02 ,  A61Q5/04 ,  A61Q17/04 ,  C07C255/44 ,  C07C317/50 ,  C07F7/08 ,  C09K3/00 ,  A61K7/42 ,  A61K7/021 ,  A61K7/06

Abstract: PROBLEM TO BE SOLVED: To obtain a cosmetic composition intended for photo-protection of the skin and/or the hair. SOLUTION: This invention relates to a cosmetic composition for topical use containing, in a cosmetically acceptable support, at least one compound of formula (1) or formula (2) [X1 represents R3 -(C=O), R3 -SO2 or R3 -O-(C=O); X2 represents (C=O)-R'3 -(C=O), SO2 -R'3 -SO2 or (C=O)-O-R'3 -O-(C=O); Y represents (C=O)-R4 or SO2 R5 ; R2 represents a 1-8C alkyl group; (n) is 0, 1 or 2; R3 represents a 1-30C alkyl or a 3-30C alkenyl; R'3 represents a single bond or a bivalent 1-30C alkylene or 3-30C alkenylene; R4 represents OR6 or NHR; R5 represents a 1-30C alkyl or phenyl nucleus; R6 represent a 1-30C alkyl or a 3-30C alkenyl]. The compound of formula (2) is a new compound.

公开(公告)号：JP2000136120A

公开(公告)日：2000-05-16

申请号：JP21432799

申请日：1999-07-28

Applicant: OREAL

Inventor： FORESTIER SERGE ,  RICHARD HERVE ,  ALLARD DELPHINE ,  CANDAU DIDIER

IPC: A61K8/00 ,  A61K8/35 ,  A61K8/58 ,  A61Q1/00 ,  A61Q1/02 ,  A61Q5/00 ,  A61Q17/04 ,  C07F7/08 ,  C09K3/00 ,  A61K7/42 ,  A61K7/02 ,  A61K7/06

Abstract: PROBLEM TO BE SOLVED: To obtain an easily applicable light-stability improving agent capable of substantially and remarkably improving a photochemical stability and useful for cosmetic use, etc., by combining a benzal malonate silane with a dibenzoylmethane derivative. SOLUTION: The objective agent is produced by adding an active amount of at least one kind of benzal malonate silane of formula I [R1 to R3 are each a (halogenated) 1-10C alkyl or phenyl; R4 and R5 are each H, hydroxyl, a 1-6C alkyl or the like; R6 and R7 are each a 1-8C alkyl; (a) is 0 or 1; Y is a bivalent group corresponding to formula II (R8 is H or a 1-5C alkyl; (p) is 1-10), etc.], to a light-shielding cosmetic composition containing a dibenzoylmethane derivative (preferably 2-methyldibenzoylmethane, 4-methyldibenzoylmethane, etc.).

公开(公告)号：JPH10324620A

公开(公告)日：1998-12-08

申请号：JP5549898

申请日：1998-03-06

Applicant: OREAL

Inventor： FORESTIER SERGE ,  RICHARD HERVE ,  ALLARD DELPHINE ,  CANDAU DIDIER

IPC: A61K8/00 ,  A61K8/35 ,  A61K8/58 ,  A61Q1/00 ,  A61Q1/02 ,  A61Q5/00 ,  A61Q17/04 ,  C07F7/08 ,  C09K3/00 ,  A61K7/42 ,  A61K7/44

Abstract: PROBLEM TO BE SOLVED: To obtain the subject composition useful as a cosmetic improved in the photochemical stabilization and/or a skin-scientific composition by using benzal malonate silane and dibenzoyl methane derivative in combination. SOLUTION: This composition is obtained by formulating a benzal malonate silane of the formula R , R and R are each a halogenated 1-10C alkyl or phenyl; R and R are each H, hydroxyl, etc.; R and R are each an 1-8C alkyl; (a) is 0 or 1; Y is a divalent group corresponding to -CR =CH-[C(R )2 ]p - (R is H and an 1-5 C alkyl; (p) is 1-10) and the like}, e.g. dimethyl 2-[3- methoxy-4-(3-trimethylsilanylpropyloxy)benzylidenelmalonate, in an amount of 0.01-10 wt.%, more suitably 0.03-5 wt.%, based on the whole weight of the composition containing a dibenzoylmethane derivative (e.g. 4-tert-butyl-4'- methoxybenzoylmethane).