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公开(公告)号：CA2850911C
公开(公告)日：2017-04-18
申请号：CA2850911
申请日：2012-09-27
Applicant: ORIENTAL YEAST CO LTD
Inventor： KODOI RIE , TAKAHASHI TAKAYASU , OKA OSAMU , URASAKI HIROMI
Abstract: A method for producing a high-zinc-content yeast extract, including extracting the high-zinc-content yeast extract by suspending zinc-containing yeast into a solution containing a carboxylic acid, a carboxylic acid salt, or both thereof to thereby obtain a suspension liquid, and separating a solid component and a liquid component of the suspension liquid; the high-zinc-content yeast extract; food; and an agent for maintaining and restoring a green color of vegetables.
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公开(公告)号：AU2012319660A1
公开(公告)日：2014-04-24
申请号：AU2012319660
申请日：2012-09-27
Applicant: ORIENTAL YEAST CO LTD
Inventor： KODOI RIE , TAKAHASHI TAKAYASU , OKA OSAMU , URASAKI HIROMI
Abstract: A method for producing a zinc-rich yeast extract, the method comprising an extraction step for suspending a yeast containing zinc in a solution including carboxylic acid and/or carboxylic acid salt, and separating the solid component and liquid component of the resulting suspension; a zinc-rich yeast extract; and a green-retaining/-restoring agent for food and vegetables.
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公开(公告)号：DE69915416T2
公开(公告)日：2005-01-13
申请号：DE69915416
申请日：1999-07-28
Applicant: ORIENTAL YEAST CO LTD
Inventor： MATSUKAWA HIROKAZU , OKA OSAMU , FUJITA TUYOSI , SAKAKIBARA HITOSHI , SUGIYAMA TATSUO
Abstract: The present invention relates to an enzyme immunoassay method for assaying calcium ion, including putting calcium-dependent glutamate dehydrogenase, namely glutamate dehydrogenase (GLDH) never expressing its activity in the absence of calcium ion, in contact to the calcium ion in a sample to assay the enzyme activity of the GLDH, the activity changing depending on the calcium ion concentration in the sample; and the invention also relates to an assay reagent for use in the same. Because the reagent is very stable in a solution state under storage, the reagent can be incorporated in a liquid reagent. Thus, the calcium in a biological material or other samples can be assayed in a simple and accurate manner.
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公开(公告)号：DE69915416D1
公开(公告)日：2004-04-15
申请号：DE69915416
申请日：1999-07-28
Applicant: ORIENTAL YEAST CO LTD
Inventor： MATSUKAWA HIROKAZU , OKA OSAMU , FUJITA TUYOSI , SAKAKIBARA HITOSHI , SUGIYAMA TATSUO
Abstract: The present invention relates to an enzyme immunoassay method for assaying calcium ion, including putting calcium-dependent glutamate dehydrogenase, namely glutamate dehydrogenase (GLDH) never expressing its activity in the absence of calcium ion, in contact to the calcium ion in a sample to assay the enzyme activity of the GLDH, the activity changing depending on the calcium ion concentration in the sample; and the invention also relates to an assay reagent for use in the same. Because the reagent is very stable in a solution state under storage, the reagent can be incorporated in a liquid reagent. Thus, the calcium in a biological material or other samples can be assayed in a simple and accurate manner.
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公开(公告)号：SG11201508172PA
公开(公告)日：2015-11-27
申请号：SG11201508172P
申请日：2014-03-26
Applicant: ORIENTAL YEAST CO LTD
Inventor： YUKAWA MAI , KAWAI RYO , WADA KUNIKO , YAMADA SHIGERU , OKA OSAMU
IPC: A23L5/41
Abstract: Provided is a method for manufacturing a yeast extract containing copper includes an extraction step wherein yeast containing copper is suspended in a solution that contains an amino acid or a salt thereof and the solid components and liquid components of the suspension obtained are separated with the amino acid or salt thereof being water-soluble. Also provided are a yeast extract containing copper, a food product, and a green color preserving and restoring agent for vegetables.
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Patent Agency Ranking
公开(公告)号：DE3204569A1
公开(公告)日：1982-11-11
申请号：DE3204569
申请日：1982-02-10
Applicant: NISSHIN FLOUR MILLING CO , ORIENTAL YEAST CO LTD
Inventor： MAEDA KOJI , OKA OSAMU
IPC: C12N9/99 , A61K36/899 , A61K38/55 , A61K38/57 , C07K1/16 , C07K1/30 , C07K14/00 , C07K14/415 , C12Q1/40 , C07G7/00
Abstract: New alpha -amylase inhibitor from wheat (WAI-53). The inhibitor is characterized especially by having molecular weight of 24,000 as determined by gel filtration, giving a single band at an electrophoretic mobility of 0.53 on polyacrylamide gel electrophoresis according to the Davis Disc Electrophoresis Method and producing saturation curves of WAI-53 with human salivary alpha-amylase and with human pancreatic alpha-amylase with a ratio of the amount of WAI-53 required to produce 50% inhibition of human salivary alpha -amylase to that of human pancreatic amylase above 1:250. The alpha-amylase inhibitor is used for quantitative analysis of alpha-amylase isozymes in body fluid.
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公开(公告)号：JP2001061498A
公开(公告)日：2001-03-13
申请号：JP24464399
申请日：1999-08-31
Applicant: ORIENTAL YEAST CO LTD
Inventor： MINATO HIDEKI , MATSUKAWA HIROKAZU , KODA SEIICHI , OKA OSAMU
IPC: C12N9/02 , C12N9/08 , C12Q1/26 , C12Q1/28 , C12Q1/30 , C12Q1/32 , C12Q1/48 , C12Q1/52 , G01N33/68
Abstract: PROBLEM TO BE SOLVED: To obtain a reduced coenzyme solution capable of maintaining high stability for a long term and useful e.g. as a liquid reagent for clinical inspection by including an active oxygen-removing substance such as superoxide dismutase or catalase in a reduced coenzyme solution. SOLUTION: The objective stable reduced coenzyme solution useful e.g. for a reagent for clinical test for diagnosing various diseases e.g. as a liquid reagents for measuring aspartate aminotransferase (AST), alanine aminotransferase (ALT), a free fatty acid, urea nitrogen, creatinine, etc., which are metabolites and enzymes in blood, serum, blood plasma, body fluid and an urine specimen is obtained by adding at least one active oxygen-removing substance selected from superoxide dismutase and/or catalase in a solution of a reduced coenzyme such as a reduced nicotinamide-adenine dinucleotide (NADH) and/or a reduced nicotinamide adenine dinucleotide phosphate (NADPH).
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公开(公告)号：JPH11346781A
公开(公告)日：1999-12-21
申请号：JP17664398
申请日：1998-06-09
Applicant: AGENCY IND SCIENCE TECHN , MIYAZAKI KENTARO , ORIENTAL YEAST CO LTD
Inventor： MATSUKAWA HIROKAZU , OKA OSAMU , FUJITA TAKESHI , MIYAZAKI KENTARO
Abstract: PROBLEM TO BE SOLVED: To obtain an ammonia quenching liquid reagent capable of rapidly quenching ammonia by including thermoduric isocitrate dehydrogenase which not only responds to both NADP and NAD but also shows excellent stability at alkaline pH. SOLUTION: The objective ammonia quenching liquid reagent is obtained by including thermoduric isocitrate dehydrogenase which not only responds to both NADP and NAD but also shows excellent stability at alkaline pH and is at least one of recombinant enzymes or the like produced from a transformant obtained by inserting an expression vector having the gene information of an enzyme obtained by synthesis, an enzyme obtained by extracting from cultured products of bacteria belonging to the genus Thermus, e.g. Thermus thermophillus and/or Thermus aquaticus, or the enzyme arising from bacteria belonging to the genus Thermus. The reagent is used to quench ammonia in a test substance when urea, creatinine or creatine in the test substance, e.g. urine, serum or the like, is measured.
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公开(公告)号：JPS59163555A
公开(公告)日：1984-09-14
申请号：JP3673683
申请日：1983-03-08
Applicant: Oriental Denki Kk , Oriental Yeast Co Ltd
Inventor： OOHASHI MINORU , ARAKAWA NOBUHIKO , OKA OSAMU , NUMAZAWA KENICHI , UTSUKI YOSHIO
IPC: G01N27/416 , C12Q1/00 , C12Q1/26 , G01N33/487
CPC classification number: C12Q1/26 , C12Q1/001 , C12Q1/42 , C12Q1/48 , G01N27/327 , G01N2333/9029 , G01N2333/90694 , G01N2333/91142
Abstract: PURPOSE: To analyse qualitatively from the kind and the adding order of added catalysts and to analyze quantitatively from the decrease of the output by adding successively plural biocatalysts which initiate the absorption reaction of dissolved oxygen, oxidizing selectively and stepwise plural components, and obtaining a step-down curve of the dissolved oxygen.
CONSTITUTION: A DO sensor 2 is fixed to the side wall of a small vessel 1, and the upper part of the vessel is covered with a plug 4 provided with a small hole 3 to prevent the intrusion of oxygen from the outside. A reaction control agent can be injected with a microsyringe etc. through the hole. The reaction temp. is controlled by circulating the water 6 at constant temp. through a jacket 5, and the reaction liquid is mixed and stirred by a magnetic stirrer 7. Several oxidizing enzymes having different components to be expected are added successively, and a qualitative analysis is made by judging by which enzyme the oxygen absorption is initiated from the presence or the absence of a step-down phenomenon in the curve. Since the decrease of the output, between the time prior to the addition of the catalysts and the time when the oxygen absorbing reaction is stopped, corresponds to the concn. of the component which responds to the function of the catalyst, the quantitative analysis can be made simultaneously with the qualitative analysis.
COPYRIGHT: (C)1984,JPO&JapioAbstract translation: 目的：从添加催化剂的种类和添加顺序进行定性分析，并通过连续添加引发溶解氧吸收反应的多个生物催化剂，从产生量的降低定量分析，选择性和逐步氧化多种成分，并获得步骤 下降曲线的溶解氧。 构成：DO传感器2固定在小容器1的侧壁上，容器的上部被设置有小孔3的塞子4覆盖，以防止从外部侵入氧气。 反应控制剂可以通过孔注入微量注射器等。 反应温度 通过使恒定温度下的水6循环来控制。 通过夹套5将反应液体通过磁力搅拌器7进行混合搅拌。依次加入几种预期不同成分的氧化酶，通过判断从哪种酶开始氧吸收来进行定性分析 在曲线中存在或不存在降压现象。 由于输出的减少，在催化剂添加之前的时间与氧吸收反应停止的时间之间，相当于浓度。 的响应催化剂功能的组分，定量分析可以与定性分析同时进行。
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公开(公告)号：JPS58113385A
公开(公告)日：1983-07-06
申请号：JP21132781
申请日：1981-12-28
Applicant: ORIENTAL YEAST CO LTD
Inventor： NAITOU JIYUNICHI , OOHASHI MINORU , NUMAZAWA KENICHI , OKA OSAMU
IPC: C25B9/00 , C25B9/08 , C25B13/00 , G01N27/40 , G01N27/404
Abstract: PURPOSE:To produce a diaphragm holding body having no pinholes and creases inexpensively in high yields by melt sticking only the parts excluding the central hole of the holding body by heating and at the same time by grasping the diaphragm covering the central hole of said holding body flatly without applying heat thereto. CONSTITUTION:Beforehand, a thermocompression bonding end part 33 is heated up to the melt-sticking temp. of a diaphragm 1 by a heater 17, a temp. measuring body 18, and a temp. controller 19. Thereafter, the operator brings down a handle 22 by hand until a thermocompression bonding body 14 abuts on said end part, then a diaphragm 1 covering the central hole of a holding body 2 is grasped flatly by means of the 1st grasping plate 15 and the 2nd grasping plate 12. The part 33 presses and sticks the diaphragm provided in the parts excluding the central hole of the body 2 and the parts 11 near the central hole to the body 2 by heting, thereby melt-sticking the diaphragm 1 to the body 2. When the operatore leaves the hand from the handle 22 after the melt sticking, the dipharagm holding body having no pinholes and creases is obtained.
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