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公开(公告)号:AT320444T
公开(公告)日:2006-04-15
申请号:AT92307785
申请日:1992-08-26
Applicant: SCRIPPS RESEARCH INST
Inventor: CHISARI FRANCIS V , FERRARI CARLO , PENNA AMALIA , MISSALE GABRIELE
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公开(公告)号:NZ270625A
公开(公告)日:1996-12-20
申请号:NZ27062595
申请日:1995-03-03
Applicant: SCRIPPS RESEARCH INST
Inventor: CHISARI FRANCIS V , FERRARI CARLO , PENNA AMALIA , MISSALE GABRIELE
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公开(公告)号:CZ42894A3
公开(公告)日:1995-02-15
申请号:CS4289492
申请日:1992-08-26
Applicant: SCRIPPS RESEARCH INST
Inventor: CHISARI FRANCIS V , FERRARI CARLO , PENNA AMALIA
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公开(公告)号:CA2115927A1
公开(公告)日:1993-03-04
申请号:CA2115927
申请日:1992-08-26
Applicant: SCRIPPS RESEARCH INST
Inventor: CHISARI FRANCIS V , FERRARI CARLO , PENNA AMALIA
IPC: C12N15/09 , A61K9/127 , A61K38/00 , A61K39/00 , A61K39/29 , A61P1/16 , A61P31/12 , A61P31/20 , C07K7/06 , C07K7/08 , C07K14/00 , C07K14/02 , C07K14/47 , C07K19/00 , C12N15/51 , C12Q1/02 , C12Q1/70 , A61K39/295 , A61K39/385 , A61K39/39
Abstract: 2115927 9303753 PCTABS00020 Peptides are used to define epitopes that stimulate HLA-restricted cytotoxic T lymphocyte activity against hepatitis B virus antigens. The peptides are derived from regions of HBV nucleocapsid, envelope, polymerase and the transcriptional transactivator X protein, and are particularly useful in treating or preventing HBV infection, including methods for stimulating the immune response of chronically infected individuals to respond to HBV antigens. Pharmaceutical compositions and hepatitis B vaccines which comprise the peptides and physiologically acceptable carriers can be employed in conjunction with other HBV vaccines to provide more effective immunity against the disease. Methods for identifying individuals who are particularly susceptible to developing chronic HBV infection and who can be targeted for treatment by the CTL peptides are also provided.
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公开(公告)号:HU9400582D0
公开(公告)日:1994-07-28
申请号:HU9400582
申请日:1992-08-26
Applicant: SCRIPPS RESEARCH INST
Inventor: CHISARI FRANCIS V , FERRARI CARLO , PENNA AMALIA
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公开(公告)号:NO940661L
公开(公告)日:1994-04-19
申请号:NO940661
申请日:1994-02-25
Applicant: SCRIPPS RESEARCH INST
Inventor: CHISARI FRANCIS V , FERRARI CARLO , PENNA AMALIA
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公开(公告)号:NO940661D0
公开(公告)日:1994-02-25
申请号:NO940661
申请日:1994-02-25
Applicant: SCRIPPS RESEARCH INST
Inventor: CHISARI FRANCIS V , FERRARI CARLO , PENNA AMALIA
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公开(公告)号:ZA926440B
公开(公告)日:1993-06-07
申请号:ZA926440
申请日:1992-08-26
Applicant: SCRIPPS RESEARCH INST
Inventor: CHISARI FRANCIS V , FERRARI CARLO , PENNA AMALIA , MISSALE GABRIELE
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公开(公告)号:DE69233607T2
公开(公告)日:2006-11-30
申请号:DE69233607
申请日:1992-08-26
Applicant: SCRIPPS RESEARCH INST
Inventor: CHISARI FRANCIS V , FERRARI CARLO , PENNA AMALIA , MISSALE GABRIELE
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公开(公告)号:DE69233607D1
公开(公告)日:2006-05-11
申请号:DE69233607
申请日:1992-08-26
Applicant: SCRIPPS RESEARCH INST
Inventor: CHISARI FRANCIS V , FERRARI CARLO , PENNA AMALIA , MISSALE GABRIELE
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